Pyrithiamine as a substrate for thiamine pyrophosphokinase

Journal of Biological Chemistry

Volumn 281, Issue 10, 2006, Pages 6601-6607

  Liu, Jing Yuan ^a   Timm, David E ^b   Hurley, Thomas D ^a,c  

^a INDIANA UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; ENZYMES; MASS SPECTROMETRY; METABOLISM; NEUROLOGY; PHOSPHATES; REACTION KINETICS;

ENZYMATIC PRODUCTION; NUCLEOSIDE TRIPHOSPHATE; PYROPHOSPHOKINASE; THIAMINE PYROPHOSPHOKINASE TRANSFERS;

AMINES;

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; COCARBOXYLASE; MAGNESIUM ION; PYRITHIAMINE; PYRITHIAMINE PYROPHOSPHATE; THIAMINE PYROPHOSPHOKINASE; UNCLASSIFIED DRUG; MAGNESIUM;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME BINDING; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SYNTHESIS; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY; ANIMAL; BINDING SITE; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ANIMALIA;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MAGNESIUM; MICE; PROTEIN STRUCTURE, TERTIARY; PYRITHIAMINE; SUBSTRATE SPECIFICITY; THIAMIN PYROPHOSPHOKINASE;

EID: 33646594715     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M510951200     Document Type: Article

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