DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation

Seminars in Cancer Biology

Volumn 37-38, Issue , 2016, Pages 51-64

  Mladenov, Emil ^a   Magin, Simon ^a   Soni, Aashish ^a   Iliakis, George ^a  

^a UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

Author keywords

alt EJ; c NHEJ; Cell cycle regulation; Cell growth regulation; DNA end resection; Double strand break repair; HRR; Pathway choice; SSA

Indexed keywords

CHEMICAL AGENT; DNA; DOUBLE STRANDED DNA; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; SINGLE STRANDED DNA;

ALTERNATIVE END JOINING; CELL CYCLE PHASE; CELL CYCLE REGULATION; CELL PROLIFERATION; DNA END JOINING REPAIR; DNA REPAIR; DNA STRAND BREAKAGE; DOUBLE STRANDED DNA BREAK; EUKARYOTE; EUKARYOTIC CELL; GENE LOCATION; GENOMIC INSTABILITY; GROWTH CURVE; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IONIZING RADIATION; NEOPLASM; NONHUMAN; PROTEIN FUNCTION; RADIATION RESPONSE; RECOMBINATION REPAIR; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SINGLE STRAND ANNEALING; CELL CYCLE; GENETICS; IMMUNOLOGY; PATHOLOGY;

CELL CYCLE; CELL PROLIFERATION; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; GENOMIC INSTABILITY; HUMANS; NEOPLASMS; RECOMBINATIONAL DNA REPAIR;

EID: 84969262470     PISSN: 1044579X     EISSN: 10963650     Source Type: Journal    
DOI: 10.1016/j.semcancer.2016.03.003     Document Type: Review

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