CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination

EMBO Reports

Volumn 13, Issue 6, 2012, Pages 561-568

  Falck, Jacob ^a,b,d   Forment, Josep V ^a   Coates, Julia ^a   Mistrik, Martin ^b,c   Lukas, Jiri ^b   Bartek, Jiri ^b,c   Jackson, Stephen P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^c PALACKÝ UNIVERSITY   (Czech Republic)

^d NOVO NORDISK A S   (Denmark)

Author keywords

cyclin dependent kinase; end joining; homologous recombination; NBS1; replication restart

Indexed keywords

CYCLIN DEPENDENT KINASE; NIBRIN;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; DNA REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION;

AMINO ACID SUBSTITUTION; CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; DNA CLEAVAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA REPLICATION; DNA-BINDING PROTEINS; HOMOLOGOUS RECOMBINATION; HUMANS; MUTAGENESIS, SITE-DIRECTED; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE;

EID: 84861843272     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2012.58     Document Type: Article

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