DNA-PK autophosphorylation facilitates Artemis endonuclease activity

EMBO Journal

Volumn 25, Issue 16, 2006, Pages 3880-3889

  Goodarzi, Aaron A ^a   Yu, Yaping ^b   Riballo, Enriqueta ^a   Douglas, Pauline ^b   Walker, Sarah A ^a   Ye, Ruiqiong ^b   Härer, Christine ^a   Marchetti, Caterina ^a   Morrice, Nick ^c   Jeggo, Penny A ^a   Lees Miller, Susan P ^b  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Artemis; Autophosphorylation; DNA PK; Nonhomologous end joining

Indexed keywords

ATM PROTEIN; DNA DEPENDENT PROTEIN KINASE; DOUBLE STRANDED DNA; ENDONUCLEASE; ENZYME ARTEMIS; KU ANTIGEN; MUTANT PROTEIN; SERINE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME SUBUNIT; GENE TARGETING; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION;

CATALYTIC DOMAIN; DNA; DNA HELICASES; DNA REPAIR; DNA, SINGLE-STRANDED; DNA-ACTIVATED PROTEIN KINASE; ENDONUCLEASES; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN CONFORMATION; RECOMBINATION, GENETIC; SERINE;

EID: 33748089029     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601255     Document Type: Article

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