Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks

DNA Repair

Volumn 9, Issue 12, 2010, Pages 1299-1306

  Williams, Gareth J ^a   Lees Miller, Susan P ^b   Tainer, John A ^a,c  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Allostery; ATPase; BRCT domains; Crystal structures; FHA domain; Nuclease

Indexed keywords

ATM PROTEIN; DOUBLE STRANDED DNA; MRE11 PROTEIN; NIBRIN; RAD50 PROTEIN;

COMPLEX FORMATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; HOMOLOGOUS RECOMBINATION; HUMAN; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REVIEW;

CELL CYCLE PROTEINS; DIMERIZATION; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION;

EID: 78649445307     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2010.10.001     Document Type: Review

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