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Volumn 22, Issue 6, 2006, Pages 719-729

Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

Author keywords

CELLCYCLE; DNA

Indexed keywords

BINDING PROTEIN; BRCA2 PROTEIN; PALB2 PROTEIN; UNCLASSIFIED DRUG;

EID: 33745200945     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2006.05.022     Document Type: Article
Times cited : (692)

References (56)
  • 3
    • 0032574733 scopus 로고    scopus 로고
    • The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment
    • Chen P.L., Chen C.F., Chen Y., Xiao J., Sharp Z.D., and Lee W.H. The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment. Proc. Natl. Acad. Sci. USA 95 (1998) 5287-5292
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5287-5292
    • Chen, P.L.1    Chen, C.F.2    Chen, Y.3    Xiao, J.4    Sharp, Z.D.5    Lee, W.H.6
  • 5
    • 7444222440 scopus 로고    scopus 로고
    • Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2
    • Daniels M.J., Wang Y., Lee M., and Venkitaraman A.R. Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2. Science 306 (2004) 876-879
    • (2004) Science , vol.306 , pp. 876-879
    • Daniels, M.J.1    Wang, Y.2    Lee, M.3    Venkitaraman, A.R.4
  • 7
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J., Muthuswamy S.K., and Brugge J.S. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30 (2003) 256-268
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 8
    • 15844373362 scopus 로고    scopus 로고
    • CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
    • Esashi F., Christ N., Gannon J., Liu Y., Hunt T., Jasin M., and West S.C. CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature 434 (2005) 598-604
    • (2005) Nature , vol.434 , pp. 598-604
    • Esashi, F.1    Christ, N.2    Gannon, J.3    Liu, Y.4    Hunt, T.5    Jasin, M.6    West, S.C.7
  • 11
    • 0032512067 scopus 로고    scopus 로고
    • BRCA2 associates with acetyltransferase activity when bound to P/CAF
    • Fuks F., Milner J., and Kouzarides T. BRCA2 associates with acetyltransferase activity when bound to P/CAF. Oncogene 17 (1998) 2531-2534
    • (1998) Oncogene , vol.17 , pp. 2531-2534
    • Fuks, F.1    Milner, J.2    Kouzarides, T.3
  • 12
    • 0037509859 scopus 로고    scopus 로고
    • The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage
    • Groisman R., Polanowska J., Kuraoka I., Sawada J., Saijo M., Drapkin R., Kisselev A.F., Tanaka K., and Nakatani Y. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. Cell 113 (2003) 357-367
    • (2003) Cell , vol.113 , pp. 357-367
    • Groisman, R.1    Polanowska, J.2    Kuraoka, I.3    Sawada, J.4    Saijo, M.5    Drapkin, R.6    Kisselev, A.F.7    Tanaka, K.8    Nakatani, Y.9
  • 14
    • 26444570009 scopus 로고    scopus 로고
    • Dynamics of DNA repair suggested by the subcellular localization of Brca1 and Brca2 proteins
    • Huber L.J., and Chodosh L.A. Dynamics of DNA repair suggested by the subcellular localization of Brca1 and Brca2 proteins. J. Cell. Biochem. 96 (2005) 47-55
    • (2005) J. Cell. Biochem. , vol.96 , pp. 47-55
    • Huber, L.J.1    Chodosh, L.A.2
  • 19
    • 1342280371 scopus 로고    scopus 로고
    • Phosphorylation of BRCA2 by the Polo-like kinase Plk1 is regulated by DNA damage and mitotic progression
    • Lee M., Daniels M.J., and Venkitaraman A.R. Phosphorylation of BRCA2 by the Polo-like kinase Plk1 is regulated by DNA damage and mitotic progression. Oncogene 23 (2004) 865-872
    • (2004) Oncogene , vol.23 , pp. 865-872
    • Lee, M.1    Daniels, M.J.2    Venkitaraman, A.R.3
  • 20
    • 0347991859 scopus 로고    scopus 로고
    • Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein
    • Lomonosov M., Anand S., Sangrithi M., Davies R., and Venkitaraman A.R. Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein. Genes Dev. 17 (2003) 3017-3022
    • (2003) Genes Dev. , vol.17 , pp. 3017-3022
    • Lomonosov, M.1    Anand, S.2    Sangrithi, M.3    Davies, R.4    Venkitaraman, A.R.5
  • 22
    • 14044251525 scopus 로고    scopus 로고
    • The BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repair
    • Lu H., Guo X., Meng X., Liu J., Allen C., Wray J., Nickoloff J.A., and Shen Z. The BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repair. Mol. Cell. Biol. 25 (2005) 1949-1957
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 1949-1957
    • Lu, H.1    Guo, X.2    Meng, X.3    Liu, J.4    Allen, C.5    Wray, J.6    Nickoloff, J.A.7    Shen, Z.8
  • 24
    • 0033026065 scopus 로고    scopus 로고
    • Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals
    • Marston N.J., Richards W.J., Hughes D., Bertwistle D., Marshall C.J., and Ashworth A. Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals. Mol. Cell. Biol. 19 (1999) 4633-4642
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4633-4642
    • Marston, N.J.1    Richards, W.J.2    Hughes, D.3    Bertwistle, D.4    Marshall, C.J.5    Ashworth, A.6
  • 26
    • 0035099044 scopus 로고    scopus 로고
    • BRCA2 is required for homology-directed repair of chromosomal breaks
    • Moynahan M.E., Pierce A.J., and Jasin M. BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell 7 (2001) 263-272
    • (2001) Mol. Cell , vol.7 , pp. 263-272
    • Moynahan, M.E.1    Pierce, A.J.2    Jasin, M.3
  • 28
    • 0347381286 scopus 로고    scopus 로고
    • Immunoaffinity purification of mammalian protein complexes
    • Nakatani Y., and Ogryzko V. Immunoaffinity purification of mammalian protein complexes. Methods Enzymol. 370 (2003) 430-444
    • (2003) Methods Enzymol. , vol.370 , pp. 430-444
    • Nakatani, Y.1    Ogryzko, V.2
  • 29
    • 0036488497 scopus 로고    scopus 로고
    • Modifiers of risk of hereditary breast and ovarian cancer
    • Narod S.A. Modifiers of risk of hereditary breast and ovarian cancer. Nat. Rev. Cancer 2 (2002) 113-123
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 113-123
    • Narod, S.A.1
  • 30
    • 0032054311 scopus 로고    scopus 로고
    • A large deletion disrupts the exon 3 transcription activation domain of the BRCA2 gene in a breast/ovarian cancer family
    • Nordling M., Karlsson P., Wahlstrom J., Engwall Y., Wallgren A., and Martinsson T. A large deletion disrupts the exon 3 transcription activation domain of the BRCA2 gene in a breast/ovarian cancer family. Cancer Res. 58 (1998) 1372-1375
    • (1998) Cancer Res. , vol.58 , pp. 1372-1375
    • Nordling, M.1    Karlsson, P.2    Wahlstrom, J.3    Engwall, Y.4    Wallgren, A.5    Martinsson, T.6
  • 33
    • 4344717012 scopus 로고    scopus 로고
    • BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage
    • Schoenfeld A.R., Apgar S., Dolios G., Wang R., and Aaronson S.A. BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage. Mol. Cell. Biol. 24 (2004) 7444-7455
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7444-7455
    • Schoenfeld, A.R.1    Apgar, S.2    Dolios, G.3    Wang, R.4    Aaronson, S.A.5
  • 34
    • 0030850047 scopus 로고    scopus 로고
    • Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
    • Scully R., Chen J., Ochs R.L., Keegan K., Hoekstra M., Feunteun J., and Livingston D.M. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 90 (1997) 425-435
    • (1997) Cell , vol.90 , pp. 425-435
    • Scully, R.1    Chen, J.2    Ochs, R.L.3    Keegan, K.4    Hoekstra, M.5    Feunteun, J.6    Livingston, D.M.7
  • 36
    • 0037795244 scopus 로고    scopus 로고
    • BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription
    • Shin S., and Verma I.M. BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription. Proc. Natl. Acad. Sci. USA 100 (2003) 7201-7206
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7201-7206
    • Shin, S.1    Verma, I.M.2
  • 38
    • 27144447689 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 as ovarian cancer susceptibility genes
    • Sowter H., and Ashworth A. BRCA1 and BRCA2 as ovarian cancer susceptibility genes. Carcinogenesis 26 (2005) 1651-1656
    • (2005) Carcinogenesis , vol.26 , pp. 1651-1656
    • Sowter, H.1    Ashworth, A.2
  • 40
    • 33744481750 scopus 로고    scopus 로고
    • The molecular pathogenesis of fanconi anemia: recent progress
    • Taniguchi T., and D'Andrea A.D. The molecular pathogenesis of fanconi anemia: recent progress. Blood 107 (2006) 4223-4233
    • (2006) Blood , vol.107 , pp. 4223-4233
    • Taniguchi, T.1    D'Andrea, A.D.2
  • 41
    • 0037468267 scopus 로고    scopus 로고
    • BRCA2-dependent and independent formation of RAD51 nuclear foci
    • Tarsounas M., Davies D., and West S.C. BRCA2-dependent and independent formation of RAD51 nuclear foci. Oncogene 22 (2003) 1115-1123
    • (2003) Oncogene , vol.22 , pp. 1115-1123
    • Tarsounas, M.1    Davies, D.2    West, S.C.3
  • 42
    • 21644482340 scopus 로고    scopus 로고
    • Targeting the DNA repair defect of BRCA tumours
    • Turner N., Tutt A., and Ashworth A. Targeting the DNA repair defect of BRCA tumours. Curr. Opin. Pharmacol. 5 (2005) 388-393
    • (2005) Curr. Opin. Pharmacol. , vol.5 , pp. 388-393
    • Turner, N.1    Tutt, A.2    Ashworth, A.3
  • 43
    • 0033533731 scopus 로고    scopus 로고
    • Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification
    • Tutt A., Gabriel A., Bertwistle D., Connor F., Paterson H., Peacock J., Ross G., and Ashworth A. Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification. Curr. Biol. 9 (1999) 1107-1110
    • (1999) Curr. Biol. , vol.9 , pp. 1107-1110
    • Tutt, A.1    Gabriel, A.2    Bertwistle, D.3    Connor, F.4    Paterson, H.5    Peacock, J.6    Ross, G.7    Ashworth, A.8
  • 44
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman A.R. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108 (2002) 171-182
    • (2002) Cell , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1
  • 45
    • 2942705849 scopus 로고    scopus 로고
    • Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin
    • Wang X., Andreassen P.R., and D'Andrea A.D. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol. Cell. Biol. 24 (2004) 5850-5862
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 5850-5862
    • Wang, X.1    Andreassen, P.R.2    D'Andrea, A.D.3
  • 46
    • 0035057806 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 and the genetics of breast and ovarian cancer
    • Welcsh P.L., and King M.C. BRCA1 and BRCA2 and the genetics of breast and ovarian cancer. Hum. Mol. Genet. 10 (2001) 705-713
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 705-713
    • Welcsh, P.L.1    King, M.C.2
  • 47
    • 0038700698 scopus 로고    scopus 로고
    • Molecular views of recombination proteins and their control
    • West S.C. Molecular views of recombination proteins and their control. Nat. Rev. Mol. Cell Biol. 4 (2003) 435-445
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 435-445
    • West, S.C.1
  • 48
    • 0031466027 scopus 로고    scopus 로고
    • RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2
    • Wong A.K., Pero R., Ormonde P.A., Tavtigian S.V., and Bartel P.L. RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2. J. Biol. Chem. 272 (1997) 31941-31944
    • (1997) J. Biol. Chem. , vol.272 , pp. 31941-31944
    • Wong, A.K.1    Pero, R.2    Ormonde, P.A.3    Tavtigian, S.V.4    Bartel, P.L.5
  • 49
    • 0037685164 scopus 로고    scopus 로고
    • Breast and ovarian cancer
    • Wooster R., and Weber B.L. Breast and ovarian cancer. N. Engl. J. Med. 348 (2003) 2339-2347
    • (2003) N. Engl. J. Med. , vol.348 , pp. 2339-2347
    • Wooster, R.1    Weber, B.L.2
  • 51
    • 0035902551 scopus 로고    scopus 로고
    • Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining
    • Xia F., Taghian D.G., DeFrank J.S., Zeng Z.C., Willers H., Iliakis G., and Powell S.N. Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining. Proc. Natl. Acad. Sci. USA 98 (2001) 8644-8649
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 8644-8649
    • Xia, F.1    Taghian, D.G.2    DeFrank, J.S.3    Zeng, Z.C.4    Willers, H.5    Iliakis, G.6    Powell, S.N.7
  • 53
    • 14144253224 scopus 로고    scopus 로고
    • The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
    • Yang H., Li Q., Fan J., Holloman W.K., and Pavletich N.P. The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction. Nature 433 (2005) 653-657
    • (2005) Nature , vol.433 , pp. 653-657
    • Yang, H.1    Li, Q.2    Fan, J.3    Holloman, W.K.4    Pavletich, N.P.5
  • 56
    • 0033179235 scopus 로고    scopus 로고
    • BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo
    • Yuan S.S., Lee S.Y., Chen G., Song M., Tomlinson G.E., and Lee E.Y. BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo. Cancer Res. 59 (1999) 3547-3551
    • (1999) Cancer Res. , vol.59 , pp. 3547-3551
    • Yuan, S.S.1    Lee, S.Y.2    Chen, G.3    Song, M.4    Tomlinson, G.E.5    Lee, E.Y.6


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