-
1
-
-
0019374013
-
Characterization of a high molecular weight acidic nuclear protein recognised by antibodies in sera from patients with polymyositis-scleroderma overlap
-
Mimori, T. et al. Characterization of a high molecular weight acidic nuclear protein recognised by antibodies in sera from patients with polymyositis-scleroderma overlap. J. Clin. Invest. 68, 611-620 (1981).
-
(1981)
J. Clin. Invest.
, vol.68
, pp. 611-620
-
-
Mimori, T.1
-
2
-
-
0023018810
-
Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders
-
Mimori, T., Hardin, J. A. & Steitz, J. A. Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders. J. Biol. Chem. 261, 2274-2278 (1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 2274-2278
-
-
Mimori, T.1
Hardin, J.A.2
Steitz, J.A.3
-
3
-
-
0022610113
-
Identification of KI [KU, P70/P80] autoantigens and analysis of anti-KI autoantibody reactivity
-
Francoeur, A. M., Peebles, C. L., Gompper, P. T. & Tan, E. M. Identification of KI [KU, P70/P80] autoantigens and analysis of anti-KI autoantibody reactivity. J. Immunol. 136, 1648-1653 (1986).
-
(1986)
J. Immunol.
, vol.136
, pp. 1648-1653
-
-
Francoeur, A.M.1
Peebles, C.L.2
Gompper, P.T.3
Tan, E.M.4
-
4
-
-
0033612287
-
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
-
Martin, S. G., Laroche, T., Suka, N., Grunstein, M. & Gasser, S. M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97, 621-633 (1999). This paper shows that Ku dynamically associates with sites of DNA damage in vivo.
-
(1999)
Cell
, vol.97
, pp. 621-633
-
-
Martin, S.G.1
Laroche, T.2
Suka, N.3
Grunstein, M.4
Gasser, S.M.5
-
5
-
-
0035815607
-
Dimerization and nuclear localization of Ku proteins
-
Koike, M., Shiomi, T. & Koike, A. Dimerization and nuclear localization of Ku proteins. J. Biol. Chem. 276, 11167-11173 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11167-11173
-
-
Koike, M.1
Shiomi, T.2
Koike, A.3
-
6
-
-
0033539095
-
DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p
-
McAinsh, A. D., Scott-Drew, S., Murray, J. A. H. & Jackson, S. P. DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p. Curr. Biol. 9, 963-966 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 963-966
-
-
McAinsh, A.D.1
Scott-Drew, S.2
Murray, J.A.H.3
Jackson, S.P.4
-
7
-
-
0040077747
-
Dimerization, translocation and localization of Ku70 and Ku80 proteins
-
Koike, M. Dimerization, translocation and localization of Ku70 and Ku80 proteins. J. Radiat. Res. 43, 223-236 (2002).
-
(2002)
J. Radiat. Res.
, vol.43
, pp. 223-236
-
-
Koike, M.1
-
8
-
-
0029884756
-
Intracellular redistribution of Ku immunoreactivity in response to cell-cell contact and growth modulating components in the medium
-
Fewell, J. W. & Kuff, E. L. Intracellular redistribution of Ku immunoreactivity in response to cell-cell contact and growth modulating components in the medium. J. Cell Sci. 109, 1937-1946 (1996).
-
(1996)
J. Cell Sci.
, vol.109
, pp. 1937-1946
-
-
Fewell, J.W.1
Kuff, E.L.2
-
9
-
-
0037385609
-
Ku70 suppresses the apoptotic translocation of Bax to mitochrondria
-
Sawada, M. et al. Ku70 suppresses the apoptotic translocation of Bax to mitochrondria. Nature Cell Biol. 5, 320-329 (2003).
-
(2003)
Nature Cell Biol.
, vol.5
, pp. 320-329
-
-
Sawada, M.1
-
10
-
-
0033199987
-
Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb
-
Morio, T. et al. Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb. Immunity 11, 339-348 (1999).
-
(1999)
Immunity
, vol.11
, pp. 339-348
-
-
Morio, T.1
-
11
-
-
0030858967
-
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination
-
Gu, Y., Jin, S., Gao, Y., Weaver, D. & Alt, F. W. Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc. Natl Acad. Sci. USA 94, 8076-8081 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 8076-8081
-
-
Gu, Y.1
Jin, S.2
Gao, Y.3
Weaver, D.4
Alt, F.W.5
-
12
-
-
0031030095
-
Molecular and biochemical characterization of xrs mutants defective in Ku80
-
Singleton, B. K. et al. Molecular and biochemical characterization of xrs mutants defective in Ku80. Mol. Cell. Biol. 17, 1264-1273 (1997).
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1264-1273
-
-
Singleton, B.K.1
-
13
-
-
0029928176
-
Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants
-
Errami, A. et al. Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants. Mol. Cell. Biol. 16, 1519-1526 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1519-1526
-
-
Errami, A.1
-
14
-
-
0031433517
-
Growth retardation and leaky SCID phenotype of Ku70-deficient mice
-
Gu, Y. et al. Growth retardation and leaky SCID phenotype of Ku70-deficient mice. Immunity 7, 653-665 (1997).
-
(1997)
Immunity
, vol.7
, pp. 653-665
-
-
Gu, Y.1
-
15
-
-
0032113987
-
Ku70: A candidate tumor suppressor gene for murine T cell lymphoma
-
Li, G. C. et al. Ku70: a candidate tumor suppressor gene for murine T cell lymphoma. Mol. Cell 2, 1-8 (1998).
-
(1998)
Mol. Cell
, vol.2
, pp. 1-8
-
-
Li, G.C.1
-
16
-
-
0032827888
-
Deletion of Ku86 causes early onset of senescence in mice
-
Vogel, H., Lim, D.-S., Karsenty, G., Finegold, M. & Hasty, P. Deletion of Ku86 causes early onset of senescence in mice. Proc. Natl Acad. Sci. USA 96, 10770-10775 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 10770-10775
-
-
Vogel, H.1
Lim, D.-S.2
Karsenty, G.3
Finegold, M.4
Hasty, P.5
-
17
-
-
0022827675
-
Mechanism of interaction between Ku protein and DNA
-
Mimori, T. & Hardin, J. A. Mechanism of interaction between Ku protein and DNA. J. Biol. Chem. 261, 10375-10379 (1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 10375-10379
-
-
Mimori, T.1
Hardin, J.A.2
-
18
-
-
0027156140
-
EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA
-
Falzon, M., Fewell, J. W., & Kuff, E. L. EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA. J. Biol. Chem. 268, 10546-10552 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10546-10552
-
-
Falzon, M.1
Fewell, J.W.2
Kuff, E.L.3
-
19
-
-
0030746109
-
Interaction of DNA-dependent protein kinase with DNA and with Ku: Biochemical and atomic-force microscopy studies
-
Yaneva, M., Kowalewski, T. & Lieber, M. R. Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J. 16, 5098-5112 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 5098-5112
-
-
Yaneva, M.1
Kowalewski, T.2
Lieber, M.R.3
-
20
-
-
0026045833
-
Analysis of the mechanism of interaction of simian Ku protein with DNA
-
Paillard, S., & Strauss, F. Analysis of the mechanism of interaction of simian Ku protein with DNA. Nucl. Acids Res. 19, 5619-5624 (1991).
-
(1991)
Nucl. Acids Res.
, vol.19
, pp. 5619-5624
-
-
Paillard, S.1
Strauss, F.2
-
21
-
-
0028147898
-
Production and characterization of recombinant human Ku antigen
-
Ono, M., Tucker, P. W. & Capra, J. D. Production and characterization of recombinant human Ku antigen. Nucl. Acids Res. 22, 3918-3924 (1994).
-
(1994)
Nucl. Acids Res.
, vol.22
, pp. 3918-3924
-
-
Ono, M.1
Tucker, P.W.2
Capra, J.D.3
-
22
-
-
0030907318
-
Ku proteins join DNA fragments as shown by atomic force microscopy
-
Pang, D. L., Yoo, S., Dynan, W. S., Jung, M. & Dritschilo, A. Ku proteins join DNA fragments as shown by atomic force microscopy. Cancer Res. 57, 1412-1415 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 1412-1415
-
-
Pang, D.L.1
Yoo, S.2
Dynan, W.S.3
Jung, M.4
Dritschilo, A.5
-
23
-
-
0027468265
-
Binding of Ku protein to DNA
-
Blier, P. R., Griffith, A. J., Craft, J. & Hardin, J. A. Binding of Ku protein to DNA. J. Biol. Chem. 268, 7594-7601 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 7594-7601
-
-
Blier, P.R.1
Griffith, A.J.2
Craft, J.3
Hardin, J.A.4
-
24
-
-
0024356877
-
HeLa nuclear-protein recognizing DNA termini and translocating on DNA forming a regular DNA multimeric complex
-
deVries, E., Vandriel, W., Bergsma, W. G., Amberg, A. C. & Vandervliet, P. C. HeLa nuclear-protein recognizing DNA termini and translocating on DNA forming a regular DNA multimeric complex. J. Mol. Biol. 208, 65-78 (1989).
-
(1989)
J. Mol. Biol.
, vol.208
, pp. 65-78
-
-
DeVries, E.1
Vandriel, W.2
Bergsma, W.G.3
Amberg, A.C.4
Vandervliet, P.C.5
-
25
-
-
0035833664
-
Direct transfer of Ku between DNA molecules with nonhomologous ends
-
Chiu, C.-F., Lin, T.-Y. & Chou, W.-G. Direct transfer of Ku between DNA molecules with nonhomologous ends. Mutat. Res. 486, 185-194 (2001).
-
(2001)
Mutat. Res.
, vol.486
, pp. 185-194
-
-
Chiu, C.-F.1
Lin, T.-Y.2
Chou, W.-G.3
-
26
-
-
0032052815
-
Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids
-
ca.
-
(1998)
Nucl. Acids Res.
, vol.26
, pp. 1551-1559
-
-
Dynan, W.S.1
Yoo, S.2
-
27
-
-
0033198709
-
Mapping of protein-protein interactions within the DNA-dependent protein kinase complex
-
Gell, D. & Jackson, S. P. Mapping of protein-protein interactions within the DNA-dependent protein kinase complex. Nucl. Acids Res. 27, 3494-3502 (1999).
-
(1999)
Nucl. Acids Res.
, vol.27
, pp. 3494-3502
-
-
Gell, D.1
Jackson, S.P.2
-
28
-
-
0034889360
-
Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system
-
Aravind, L. & Koonin, E. V. Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system. Genome Res. 11, 1365-1374 (2001). This report, in addition to reference 46, identified the presence of Ku homologues in prokaryotes.
-
(2001)
Genome Res.
, vol.11
, pp. 1365-1374
-
-
Aravind, L.1
Koonin, E.V.2
-
29
-
-
0034161452
-
SAP - A putative DNA-binding motif involved in chromosomal organization
-
Aravind, L. & Koonin, E. V. SAP - a putative DNA-binding motif involved in chromosomal organization. Trends Biochem. Sci. 25, 112-114 (2000).
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 112-114
-
-
Aravind, L.1
Koonin, E.V.2
-
30
-
-
0035833552
-
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
-
Walker, J. R., Corpina, R. A, & Goldberg, J. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature 412, 607-614 (2001). Report of the crystal structure of Ku alone and bound to DNA, which provided enormous insight into the biochemical properties of Ku including the mechanism of DNA binding.
-
(2001)
Nature
, vol.412
, pp. 607-614
-
-
Walker, J.R.1
Corpina, R.A.2
Goldberg, J.3
-
31
-
-
0028060111
-
Similar DNA binding properties of free p70 (KU) subunit and p70/p 80 heterodimer
-
Wang, J., Satoh, M., Chou, C. & Reeves, W. H. Similar DNA binding properties of free p70 (KU) subunit and p70/p80 heterodimer. FEBS Lets. 351, 219-224 (1994).
-
(1994)
FEBS Lets.
, vol.351
, pp. 219-224
-
-
Wang, J.1
Satoh, M.2
Chou, C.3
Reeves, W.H.4
-
32
-
-
0026570651
-
Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA
-
Griffith, A. J., Blier, P. R., Mimori, T. & Hardin, J. A. Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA. J. Biol. Chem. 267, 331-338 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 331-338
-
-
Griffith, A.J.1
Blier, P.R.2
Mimori, T.3
Hardin, J.A.4
-
33
-
-
0035851127
-
The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70
-
Zhang, Z. et al. The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70. J. Biol. Chem. 276, 38231-38236 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38231-38236
-
-
Zhang, Z.1
-
34
-
-
0347627530
-
The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR)
-
Harris, R. et al. The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR). J. Mol. Biol. 335, 573-582 (2004).
-
(2004)
J. Mol. Biol.
, vol.335
, pp. 573-582
-
-
Harris, R.1
-
35
-
-
0029988716
-
Sequence-specific DNA binding by Ku autoantigen and its effects on transcription
-
Giffen, W. et al. Sequence-specific DNA binding by Ku autoantigen and its effects on transcription. Nature 380, 265-268 (1996).
-
(1996)
Nature
, vol.380
, pp. 265-268
-
-
Giffen, W.1
-
36
-
-
0345701399
-
Differential DNA binding of Ku antigen determines its involvement in DNA replication
-
Schild-Poulter, C. et al. Differential DNA binding of Ku antigen determines its involvement in DNA replication. DNA Cell Biol. 22, 65-78 (2003).
-
(2003)
DNA Cell Biol.
, vol.22
, pp. 65-78
-
-
Schild-Poulter, C.1
-
37
-
-
0027397867
-
The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
-
Gottlieb, T. M. & Jackson, S. P. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72, 131-142 (1993).
-
(1993)
Cell
, vol.72
, pp. 131-142
-
-
Gottlieb, T.M.1
Jackson, S.P.2
-
38
-
-
0027048773
-
Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II
-
Dvir, A., Peterson, S. R., Knuth, M. W., Lu, H. & Dynan, W. S. Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II. Proc. Natl Acad. Sci. USA 89, 11920-11924 (1992). References 37 and 38 show that Ku is a part of the DNA-dependent protein kinase in higher eukaryotes.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 11920-11924
-
-
Dvir, A.1
Peterson, S.R.2
Knuth, M.W.3
Lu, H.4
Dynan, W.S.5
-
39
-
-
0028263785
-
DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA
-
Suwa, A. et al. DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA. Proc. Natl Acad. Sci. USA 91, 6904-6908 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 6904-6908
-
-
Suwa, A.1
-
40
-
-
0031930488
-
DNA-dependent protein kinase: DNA binding and activation in the absence of Ku
-
Hammarsten, O. & Chu, G. DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proc. Natl Acad. Sci. USA 95, 525-530 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 525-530
-
-
Hammarsten, O.1
Chu, G.2
-
41
-
-
0030009738
-
The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
-
Chan, D. W. & Lees-Miller, S. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J. Biol. Chem. 271, 8936-8941 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8936-8941
-
-
Chan, D.W.1
Lees-Miller, S.2
-
42
-
-
0030925492
-
KARP-1: A novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity
-
Myung, K., He, D. M., Lee, S. E. & Hendrickson, E. A. KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity. EMBO J. 18, 3172-3184 (1997).
-
(1997)
EMBO J.
, vol.18
, pp. 3172-3184
-
-
Myung, K.1
He, D.M.2
Lee, S.E.3
Hendrickson, E.A.4
-
43
-
-
0037090684
-
Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK
-
Hanakahi, L. A. & West, S. C. Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK. EMBO J. 21, 2038-2044 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 2038-2044
-
-
Hanakahi, L.A.1
West, S.C.2
-
44
-
-
0037192767
-
Binding of inositol hexakisphosphate (IP6) to Ku but not to DNA-PKcs
-
Ma, Y. & Lieber, M. R. Binding of inositol hexakisphosphate (IP6) to Ku but not to DNA-PKcs. J. Biol. Chem. 277, 10756-10759 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10756-10759
-
-
Ma, Y.1
Lieber, M.R.2
-
45
-
-
0034664805
-
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
-
Hanakahi, L. A., Bartlet-Jones, M., Chappell, C., Pappin, D. & West, S. C. Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair. Cell 102, 721-729 (2000).
-
(2000)
Cell
, vol.102
, pp. 721-729
-
-
Hanakahi, L.A.1
Bartlet-Jones, M.2
Chappell, C.3
Pappin, D.4
West, S.C.5
-
46
-
-
0035816444
-
Identification of bacterial homologes of the Ku DNA-repair proteins
-
Doherty, A. J., Jackson, S. P. & Weller, G. R. Identification of bacterial homologes of the Ku DNA-repair proteins. FEBS Lett. 500, 186-188 (2001).
-
(2001)
FEBS Lett.
, vol.500
, pp. 186-188
-
-
Doherty, A.J.1
Jackson, S.P.2
Weller, G.R.3
-
47
-
-
0038700698
-
Molecular views of recombination proteins and their control
-
West, S. C. Molecular views of recombination proteins and their control. Nature Rev. Mol. Cell Biol. 4, 1-11 (2003).
-
(2003)
Nature Rev. Mol. Cell Biol.
, vol.4
, pp. 1-11
-
-
West, S.C.1
-
48
-
-
0042839614
-
Mechanism and regulation of human non-homologous DNA end-joining
-
Lieber, M. R., Ma, Y., Pannicke, U. & Schwarz, K. Mechanism and regulation of human non-homologous DNA end-joining. Nature Rev. Mol. Cell Biol. 4, 712-720 (2003). A comprehensive review of NHEJ.
-
(2003)
Nature Rev. Mol. Cell Biol.
, vol.4
, pp. 712-720
-
-
Lieber, M.R.1
Ma, Y.2
Pannicke, U.3
Schwarz, K.4
-
49
-
-
0029395076
-
Menage a trois: Double strand break repair, V(D)J recombination and DNA-PK
-
Jeggo, P. A., Taccioli, G. E. & Jackson, S. P. Menage a trois: double strand break repair, V(D)J recombination and DNA-PK. Bioessays 17, 949-957 (1995).
-
(1995)
Bioessays
, vol.17
, pp. 949-957
-
-
Jeggo, P.A.1
Taccioli, G.E.2
Jackson, S.P.3
-
50
-
-
0035839840
-
DNA double strand break repair and chromosomal translocation: Lessons from animal models
-
Ferguson, D. O. & Alt, F. W. DNA double strand break repair and chromosomal translocation: lessons from animal models. Oncogene 20, 5572-5579 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 5572-5579
-
-
Ferguson, D.O.1
Alt, F.W.2
-
51
-
-
0033560796
-
The DNA-dependent protein kinase
-
Smith, G. C. M. & Jackson, S. P. The DNA-dependent protein kinase. Genes Dev. 13, 916-934 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 916-934
-
-
Smith, G.C.M.1
Jackson, S.P.2
-
52
-
-
0032564469
-
DNA end-joining cayalyzed by human cell free extracts
-
Baumann, P. & West, S. C. DNA end-joining cayalyzed by human cell free extracts. Proc. Natl Acad. Sci. USA 95, 14066-14070 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 14066-14070
-
-
Baumann, P.1
West, S.C.2
-
53
-
-
0033231221
-
Nonhomologous DNA end joining in cell-free systems
-
Labhart, P. Nonhomologous DNA end joining in cell-free systems. Eur. J. Biochem. 265, 849-861 (1999).
-
(1999)
Eur. J. Biochem.
, vol.265
, pp. 849-861
-
-
Labhart, P.1
-
54
-
-
0032518680
-
Ku protein stimulates DNA end joining by mammalian DNA ligases: A direct role for Ku in repair of DNA double-strand breaks
-
Ramsden, D. A. & Gellert, M. Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks. EMBO J. 17, 609-614 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 609-614
-
-
Ramsden, D.A.1
Gellert, M.2
-
55
-
-
0034001205
-
Ku recruits the XRCC4-ligase IV complex to DNA ends
-
McElhinny, S. A. N., Snowden, C. M., McCarville, J. & Ramsden, D. A. Ku recruits the XRCC4-ligase IV complex to DNA ends. Mol. Cell. Biol. 20, 2996-3003 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2996-3003
-
-
McElhinny, S.A.N.1
Snowden, C.M.2
McCarville, J.3
Ramsden, D.A.4
-
56
-
-
0034714199
-
Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase
-
Chen, L., Trujillo, K., Sung, P. & Tomkinson, A. E. Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase. J. Biol. Chem. 275, 26196-26205 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26196-26205
-
-
Chen, L.1
Trujillo, K.2
Sung, P.3
Tomkinson, A.E.4
-
57
-
-
0027288231
-
A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae
-
Feldmann, H. & Winnacker, E. L. A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae. J. Biol. Chem. 268, 12895-12900 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12895-12900
-
-
Feldmann, H.1
Winnacker, E.L.2
-
58
-
-
0030033061
-
The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination
-
Siede, W., Friedl, A. A., Dianova, I., Eckardt-Schupp, F. & Friedberg, E. C. The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination. Genetics 142, 91-102 (1996).
-
(1996)
Genetics
, vol.142
, pp. 91-102
-
-
Siede, W.1
Friedl, A.A.2
Dianova, I.3
Eckardt-Schupp, F.4
Friedberg, E.C.5
-
59
-
-
0029791694
-
Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
-
Boulton, S. J. & Jackson, S. P. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J. 15, 5093-5103 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 5093-5103
-
-
Boulton, S.J.1
Jackson, S.P.2
-
60
-
-
0029971906
-
Hdf1, a yeast Ku protein homologue, is involved in illegitimate recombination, but not in homologous recombination
-
Tsukamoto, Y., Kato, J. & Ikeda, H. Hdf1, a yeast Ku protein homologue, is involved in illegitimate recombination, but not in homologous recombination. Nucl. Acids Res. 24, 2067-2072 (1996).
-
(1996)
Nucl. Acids Res.
, vol.24
, pp. 2067-2072
-
-
Tsukamoto, Y.1
Kato, J.2
Ikeda, H.3
-
61
-
-
0029954821
-
Mutations in two Ku homologues define a DNA end-joining repair pathway in Saccharomyces cerevisiae
-
Milne, G. T., Jin, S., Shannon, K. B. & Weaver, D. T. Mutations in two Ku homologues define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol. 16, 4189-4198 (1996). References 57-61 were instrumental in demonstrating Ku-dependent NHEJ in S. cerevisiae.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4189-4198
-
-
Milne, G.T.1
Jin, S.2
Shannon, K.B.3
Weaver, D.T.4
-
62
-
-
0031037649
-
DNA double-strand break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae
-
Barnes, G. & Rio, D. DNA double-strand break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA 94, 867-872 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 867-872
-
-
Barnes, G.1
Rio, D.2
-
63
-
-
0035930342
-
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf 2 complexes
-
Chen, L., Trujillo, K., Ramos, W., Sung, P. & Tomkinson, A. E. Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol. Cell 8, 1105-1115 (2001).
-
(2001)
Mol. Cell
, vol.8
, pp. 1105-1115
-
-
Chen, L.1
Trujillo, K.2
Ramos, W.3
Sung, P.4
Tomkinson, A.E.5
-
64
-
-
0036690874
-
Disruption of the Arabidopsis AtKu80 gene demonstrates an essential role for AtKu80 protein in efficient repair of DNA double-strand breaks in vivo
-
West, C. E. et al. Disruption of the Arabidopsis AtKu80 gene demonstrates an essential role for AtKu80 protein in efficient repair of DNA double-strand breaks in vivo. Plant J. 31, 517-528 (2002).
-
(2002)
Plant J.
, vol.31
, pp. 517-528
-
-
West, C.E.1
-
65
-
-
0141681150
-
Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis
-
Gallego, M. E., Bleuyard, J.-Y., Daoudal-Cotterell, S., Jallut, N. & White, C. I. Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis. Plant J. 35, 557-565 (2003).
-
(2003)
Plant J.
, vol.35
, pp. 557-565
-
-
Gallego, M.E.1
Bleuyard, J.-Y.2
Daoudal-Cotterell, S.3
Jallut, N.4
White, C.I.5
-
66
-
-
0032803238
-
The Drosophila melanogaster DmRAD54 gene plays a crucial role in double-strand break repair after P-element excision and acts synergistically with Ku70 in the repair of X-ray damage
-
Kooistra, R., Pastink, A., Zonneveld, J. B. M., Lohman, P. H. M. & Eeken, J. C. J. The Drosophila melanogaster DmRAD54 gene plays a crucial role in double-strand break repair after P-element excision and acts synergistically with Ku70 in the repair of X-ray damage. Mol. Cell. Biol. 19, 6269-6275 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6269-6275
-
-
Kooistra, R.1
Pastink, A.2
Zonneveld, J.B.M.3
Lohman, P.H.M.4
Eeken, J.C.J.5
-
67
-
-
0037077206
-
Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomes
-
Conway, C. et al. Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomes. J. Biol. Chem. 277, 21269-21277 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21269-21277
-
-
Conway, C.1
-
68
-
-
0037031655
-
Identification of a DNA nonhomologous end-joining complex in bacteria
-
Weller, G. R. et al. Identification of a DNA nonhomologous end-joining complex in bacteria. Science 297, 1686-1689 (2002). Shows that the putative Ku homologues from prokaryotes are functional homologues and are likely to have a role in NHEJ in bacteria.
-
(2002)
Science
, vol.297
, pp. 1686-1689
-
-
Weller, G.R.1
-
69
-
-
0032493889
-
Saccharomyces Ku70, Mre11/Rad50, and RPA proteins regulate adaptation to G2/M arrest after DNA damage
-
Lee, S. E. et al. Saccharomyces Ku70, Mre11/Rad50, and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94, 399-409 (1998).
-
(1998)
Cell
, vol.94
, pp. 399-409
-
-
Lee, S.E.1
-
70
-
-
15844385545
-
Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA
-
Liang, F. & Jasin, M. Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA. J. Biol. Chem. 271, 14405-14411 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14405-14411
-
-
Liang, F.1
Jasin, M.2
-
71
-
-
0037187199
-
Defining interactions between DNA-PK and ligase IV/XRCC4
-
Hsu, H.-L., Yannone, S. M. & Chen, D. J. Defining interactions between DNA-PK and ligase IV/XRCC4. DNA Repair 1, 225-235 (2002).
-
(2002)
DNA Repair
, vol.1
, pp. 225-235
-
-
Hsu, H.-L.1
Yannone, S.M.2
Chen, D.J.3
-
72
-
-
0037102588
-
Ku heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminus
-
Karmakar, P., Snowden, C. M., Ramsden, D. A. & Bohr, V. A. Ku heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminus. Nucl. Acids Res. 30, 3583-3591 (2002).
-
(2002)
Nucl. Acids Res.
, vol.30
, pp. 3583-3591
-
-
Karmakar, P.1
Snowden, C.M.2
Ramsden, D.A.3
Bohr, V.A.4
-
73
-
-
0034655912
-
Ku complex interacts with and stimulates the Werner protein
-
Cooper, M. P. et al. Ku complex interacts with and stimulates the Werner protein. Genes Dev. 14, 907-912 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 907-912
-
-
Cooper, M.P.1
-
74
-
-
0032859119
-
Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis
-
Goedecke, W., Eijpe, M., Offenberg, H. H., van Aalderen, M. & Heyting, C. Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis. Nature Genet. 23, 194-198 (1999).
-
(1999)
Nature Genet.
, vol.23
, pp. 194-198
-
-
Goedecke, W.1
Eijpe, M.2
Offenberg, H.H.3
Van Aalderen, M.4
Heyting, C.5
-
75
-
-
0033575278
-
Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences
-
Galande, S. & Kohwi-Shigematsu, T. Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences. J. Biol. Chem. 274, 20521-20528 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20521-20528
-
-
Galande, S.1
Kohwi-Shigematsu, T.2
-
76
-
-
0033594407
-
Binding of double-strand breaks in DNA by human Rad 52 protein
-
Van Dyck, E., Stasiak, A. Z., Stasiak, A. & West, S. C. Binding of double-strand breaks in DNA by human Rad52 protein. Nature 398, 728-731 (1999).
-
(1999)
Nature
, vol.398
, pp. 728-731
-
-
Van Dyck, E.1
Stasiak, A.Z.2
Stasiak, A.3
West, S.C.4
-
77
-
-
0035893363
-
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
-
Pierce, A. J., Hu, P., Han, M., Ellis, N. & Jasin, M. Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev. 15, 3237-3242 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 3237-3242
-
-
Pierce, A.J.1
Hu, P.2
Han, M.3
Ellis, N.4
Jasin, M.5
-
78
-
-
0037133699
-
DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination
-
Allen, C., Kurimasa, A., Brenneman, M. A., Chen, D. J. & Nickoloff, J. A. DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination. Proc. Natl Acad. Sci. USA 99, 3758-3763 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 3758-3763
-
-
Allen, C.1
Kurimasa, A.2
Brenneman, M.A.3
Chen, D.J.4
Nickoloff, J.A.5
-
79
-
-
0344012209
-
Rad52 and Ku bind to different DNA structures produced early in double-strand break repair
-
Ristic, D., Modesti, M., Kanaar, R. & Wyman, C. Rad52 and Ku bind to different DNA structures produced early in double-strand break repair. Nucl. Acids Res. 31, 5229-5237 (2003).
-
(2003)
Nucl. Acids Res.
, vol.31
, pp. 5229-5237
-
-
Ristic, D.1
Modesti, M.2
Kanaar, R.3
Wyman, C.4
-
80
-
-
0036498909
-
Transient association of Ku with nuclear substrates characterized using fluorescence photobleaching
-
Rodgers, W., Jordan, S. J. & Capra, J. D. Transient association of Ku with nuclear substrates characterized using fluorescence photobleaching. J. Immunol. 168, 2348-2355 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 2348-2355
-
-
Rodgers, W.1
Jordan, S.J.2
Capra, J.D.3
-
81
-
-
0032528228
-
DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C 1D
-
Yavuzer, U., Smith, G. C. M., Bliss, T., Werner, D. & Jackson, S. P. DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D. Genes Dev. 12, 2188-2199 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 2188-2199
-
-
Yavuzer, U.1
Smith, G.C.M.2
Bliss, T.3
Werner, D.4
Jackson, S.P.5
-
82
-
-
0036828213
-
Ku affects the CHK1-dependent G2 checkpoint after ionizing radiation
-
Wang, X., Li, G. C., Iliakis, G. & Wang, Y. Ku affects the CHK1-dependent G2 checkpoint after ionizing radiation. Cancer Res. 62, 6031-6034 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 6031-6034
-
-
Wang, X.1
Li, G.C.2
Iliakis, G.3
Wang, Y.4
-
83
-
-
0037068770
-
Ku affects the ATM-dependent S phase checkpoint following ionizing radiation
-
Zhou, X.-Y. et al. Ku affects the ATM-dependent S phase checkpoint following ionizing radiation. Oncogene 21, 6377-6381 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 6377-6381
-
-
Zhou, X.-Y.1
-
84
-
-
0032522564
-
Ku80 is required for immunoglobulin isotype switching
-
Casellas, R. et al. Ku80 is required for immunoglobulin isotype switching. EMBO J. 17, 2404-2411 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 2404-2411
-
-
Casellas, R.1
-
85
-
-
0032526290
-
Ku70 is required for late B cell development and immunoglobulin heavy chain class switching
-
Manis, J. P. et al. Ku70 is required for late B cell development and immunoglobulin heavy chain class switching. J. Exp. Med. 187, 2081-2089 (1998).
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2081-2089
-
-
Manis, J.P.1
-
86
-
-
0028025020
-
Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
-
Taccioli, G. E. et al. Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 265, 1442-1445 (1994).
-
(1994)
Science
, vol.265
, pp. 1442-1445
-
-
Taccioli, G.E.1
-
87
-
-
0036240127
-
The mechanism and regulation of chromosomal V(D)J recombination
-
Bassing, C. H., Swat, W. & Alt, F. W. The mechanism and regulation of chromosomal V(D)J recombination. Cell 109, S45-S55 (2002).
-
(2002)
Cell
, vol.109
-
-
Bassing, C.H.1
Swat, W.2
Alt, F.W.3
-
88
-
-
0030576534
-
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
-
Zhu, C., Bogue, M. A., Lim, D., Hasty, P. & Roth, D. B. Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86, 379-389 (1996).
-
(1996)
Cell
, vol.86
, pp. 379-389
-
-
Zhu, C.1
Bogue, M.A.2
Lim, D.3
Hasty, P.4
Roth, D.B.5
-
89
-
-
0032168766
-
DNA-PK is essential only for coding joint formation in V(D)J recombination
-
Kulesza, P. & Lieber, M. R. DNA-PK is essential only for coding joint formation in V(D)J recombination. Nucl. Acids Res. 26, 3944-3948 (1998).
-
(1998)
Nucl. Acids Res.
, vol.26
, pp. 3944-3948
-
-
Kulesza, P.1
Lieber, M.R.2
-
90
-
-
0029778191
-
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination
-
Nussenzweig, A. et al. Requirement for Ku80 in growth and immunoglobulin V(D)J recombination. Nature 382, 551-555 (1996).
-
(1996)
Nature
, vol.382
, pp. 551-555
-
-
Nussenzweig, A.1
-
91
-
-
0032585526
-
Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
-
Barnes, D. E., Stamp, G., Rosewell, I., Denzel, A. & Lindahl, T. Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Curr. Biol. 8, 1395-1398 (1998).
-
(1998)
Curr. Biol.
, vol.8
, pp. 1395-1398
-
-
Barnes, D.E.1
Stamp, G.2
Rosewell, I.3
Denzel, A.4
Lindahl, T.5
-
92
-
-
0030934860
-
Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products
-
Han, J., Steen, S. B. & Roth, D. B. Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products. Mol. Cell. Biol. 17, 2226-2234 (1997).
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2226-2234
-
-
Han, J.1
Steen, S.B.2
Roth, D.B.3
-
93
-
-
0035312286
-
Ku80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferase
-
Purugganan, M. M., Shah, S., Kearney, J. F. & Roth, D. B. Ku80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferase. Nucl. Acids Res. 29, 1636-1646 (2001).
-
(2001)
Nucl. Acids Res.
, vol.29
, pp. 1636-1646
-
-
Purugganan, M.M.1
Shah, S.2
Kearney, J.F.3
Roth, D.B.4
-
94
-
-
0037660900
-
The role of DNA breaks in genomic instability and tumorigenesis
-
Mills, K. D., Ferguson, D. O. & Alt, F. W. The role of DNA breaks in genomic instability and tumorigenesis. Immunol. Rev. 194, 77-95 (2003).
-
(2003)
Immunol. Rev.
, vol.194
, pp. 77-95
-
-
Mills, K.D.1
Ferguson, D.O.2
Alt, F.W.3
-
95
-
-
0034732239
-
DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
-
Difilippantonio, M. J. et al. DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation. Nature 404, 510-514 (2000). The first demonstration that Ku functions to prevent tumourigenesis in mammals.
-
(2000)
Nature
, vol.404
, pp. 510-514
-
-
Difilippantonio, M.J.1
-
96
-
-
0032792105
-
Involvement of DNA end-binding protein Ku in Ty element retrotransposition
-
Downs, J. A. & Jackson, S. P. Involvement of DNA end-binding protein Ku in Ty element retrotransposition. Mol. Cell. Biol. 19, 6260-6268 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6260-6268
-
-
Downs, J.A.1
Jackson, S.P.2
-
97
-
-
0033597450
-
A role for DNA-PK in retroviral DNA integration
-
Daniel, R., Katz, R. A. & Skalka, A. M. A role for DNA-PK in retroviral DNA integration. Science 284, 644-647 (1999).
-
(1999)
Science
, vol.284
, pp. 644-647
-
-
Daniel, R.1
Katz, R.A.2
Skalka, A.M.3
-
98
-
-
0035876374
-
Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection
-
Li, L. et al. Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection. EMBO J. 20, 3272-3281 (2001). References 96, 97 and 98 show the involvement of Ku in retroelement integration, in which there is no DNA DSB created in the host genome.
-
(2001)
EMBO J.
, vol.20
, pp. 3272-3281
-
-
Li, L.1
-
99
-
-
0347927261
-
The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku
-
d'Adda di Fagagna, F., Weller, G. R., Doherty, A. J. & Jackson, S. P. The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku. EMBO Rep. 4, 47-52 (2003).
-
(2003)
EMBO Rep.
, vol.4
, pp. 47-52
-
-
D'Adda Di Fagagna, F.1
Weller, G.R.2
Doherty, A.J.3
Jackson, S.P.4
-
100
-
-
0022910893
-
Localization of the gam gene of bacteriophage Mu and characterisation of the gene product
-
Akroyd, J. & Symonds, N. Localization of the gam gene of bacteriophage Mu and characterisation of the gene product. Gene 49, 273-282 (1986).
-
(1986)
Gene
, vol.49
, pp. 273-282
-
-
Akroyd, J.1
Symonds, N.2
-
101
-
-
0025306759
-
Purification of overexpressed gam gene protein from bacteriophage Mu by denaturation-renaturation techniques and a study of its DNA-binding properties
-
Abraham, Z. H. L. & Symonds, N. Purification of overexpressed gam gene protein from bacteriophage Mu by denaturation-renaturation techniques and a study of its DNA-binding properties. Biochem. J. 269, 679-684 (1990).
-
(1990)
Biochem. J.
, vol.269
, pp. 679-684
-
-
Abraham, Z.H.L.1
Symonds, N.2
-
102
-
-
0037164718
-
Live imaging of telomeres: yKu and Slr proteins define redundant telomere-anchoring pathways
-
Hediger, F., Neumann, F. R., Van Houwe, G., Dubrana, K. & Gasser, S. M. Live imaging of telomeres: yKu and Slr proteins define redundant telomere-anchoring pathways. Curr. Biol. 12, 2076-2089 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 2076-2089
-
-
Hediger, F.1
Neumann, F.R.2
Van Houwe, G.3
Dubrana, K.4
Gasser, S.M.5
-
103
-
-
0032554797
-
Telomere maintenance is dependent on activities required for end repair of double-strand breaks
-
Nugent, C. I. et al. Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr. Biol. 8, 657-660 (1998).
-
(1998)
Curr. Biol.
, vol.8
, pp. 657-660
-
-
Nugent, C.I.1
-
104
-
-
0032536861
-
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
-
Boulton, S. J. & Jackson, S. P. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J. 17, 1819-1828 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 1819-1828
-
-
Boulton, S.J.1
Jackson, S.P.2
-
105
-
-
0032076127
-
Yeast Ku as a regulator of chromosomal DNA end structure
-
Gravel, S., Larrivee, M., Labrecque, P. & Wellinger, R. J. Yeast Ku as a regulator of chromosomal DNA end structure. Science 280, 741-744 (1998).
-
(1998)
Science
, vol.280
, pp. 741-744
-
-
Gravel, S.1
Larrivee, M.2
Labrecque, P.3
Wellinger, R.J.4
-
106
-
-
0029919650
-
The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae
-
Porter, S. E., Greenwell, P. W., Ritchie, K. B. & Petes, T. D. The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucl. Acids Res. 24, 582-585 (1996).
-
(1996)
Nucl. Acids Res.
, vol.24
, pp. 582-585
-
-
Porter, S.E.1
Greenwell, P.W.2
Ritchie, K.B.3
Petes, T.D.4
-
107
-
-
0036119253
-
Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku
-
Gravel, S. & Wellinger, R. J. Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku. Mol. Cell. Biol. 22, 2182-2193 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2182-2193
-
-
Gravel, S.1
Wellinger, R.J.2
-
108
-
-
0036791764
-
Ku complex controls the replication time of DNA in telomere regions
-
Cosgrove, A. J., Nieduszynski, C. A. & Donaldson, A. D. Ku complex controls the replication time of DNA in telomere regions. Genes Dev. 16, 2485-2490 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 2485-2490
-
-
Cosgrove, A.J.1
Nieduszynski, C.A.2
Donaldson, A.D.3
-
109
-
-
0141868298
-
The Ku heterodimer performs separable activities at double strand breaks and chromosome termini
-
Bertuch, A. A. & Lundblad, V. The Ku heterodimer performs separable activities at double strand breaks and chromosome termini. Mol. Cell. Biol. 23, 8202-8215 (2003).
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8202-8215
-
-
Bertuch, A.A.1
Lundblad, V.2
-
110
-
-
0141525391
-
Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends
-
Stellwagen, A. E., Haimberger, Z. W., Veatch, J. R. & Gottschling, D. E. Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev. 17, 2384-2395 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 2384-2395
-
-
Stellwagen, A.E.1
Haimberger, Z.W.2
Veatch, J.R.3
Gottschling, D.E.4
-
111
-
-
0347683485
-
Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing
-
Roy, R., Meier, B., McAinsh, A. D., Feldmann, H. M. & Jackson, S. P. Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing. J. Biol. Chem. 279, 86-94 (2004). References 109, 110 and 111 report the identification of separation-of-function mutations in Ku80, which show separate roles for Ku in NHEJ and at telomeres.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 86-94
-
-
Roy, R.1
Meier, B.2
McAinsh, A.D.3
Feldmann, H.M.4
Jackson, S.P.5
-
112
-
-
0033783039
-
Protection of telomeres by the Ku protein in fission yeast
-
Baumann, P. & Cech, T. R. Protection of telomeres by the Ku protein in fission yeast. Mol. Biol. Cell 11, 3265-3275 (2000).
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 3265-3275
-
-
Baumann, P.1
Cech, T.R.2
-
113
-
-
0037013922
-
Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70
-
Riha, K., Watson, J. M., Parkey, J. & Shippen, D. E. Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70. EMBO J. 21, 2819-2826 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 2819-2826
-
-
Riha, K.1
Watson, J.M.2
Parkey, J.3
Shippen, D.E.4
-
114
-
-
0036682102
-
Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis KU70 mutant
-
Bundock, P., van Attikum, H. & Hooykaas, P. Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis KU70 mutant. Nucl. Acids Res. 30, 3395-3400 (2002).
-
(2002)
Nucl. Acids Res.
, vol.30
, pp. 3395-3400
-
-
Bundock, P.1
Van Attikum, H.2
Hooykaas, P.3
-
115
-
-
0037449712
-
Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast
-
Miyoshi, T., Sadaie, M., Kanoh, J. & Ishikawa, F. Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast. J. Biol. Chem. 278, 1924-1931 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1924-1931
-
-
Miyoshi, T.1
Sadaie, M.2
Kanoh, J.3
Ishikawa, F.4
-
116
-
-
0033607160
-
Ku is associated with the telomere in mammals
-
Hsu, H., Gilley, D., Blackbum, E. H. & Chen, D. J. Ku is associated with the telomere in mammals. Proc. Natl Acad. Sci. USA 96, 12454-12458 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 12454-12458
-
-
Hsu, H.1
Gilley, D.2
Blackbum, E.H.3
Chen, D.J.4
-
117
-
-
0035822641
-
Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
-
d'Adda di Fagagna, F. et al. Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells. Curr. Biol. 11, 1192-1196 (2001).
-
(2001)
Curr. Biol.
, vol.11
, pp. 1192-1196
-
-
D'Adda Di Fagagna, F.1
-
118
-
-
0037033062
-
Human Ku70/80 associates physically with telomerase through interaction with hTERT
-
Chai, W., Ford, L. P., Lenertz, L., Wright, W. E. & Shay, J. W. Human Ku70/80 associates physically with telomerase through interaction with hTERT. J. Biol. Chem. 277, 47242-47247 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47242-47247
-
-
Chai, W.1
Ford, L.P.2
Lenertz, L.3
Wright, W.E.4
Shay, J.W.5
-
119
-
-
0036566036
-
Mammalian Ku86 mediates chromosome fusions and apoptosis caused by critically short telomeres
-
Espejel, S. et al. Mammalian Ku86 mediates chromosome fusions and apoptosis caused by critically short telomeres. EMBO J. 21, 2207-2219 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 2207-2219
-
-
Espejel, S.1
-
120
-
-
0036792871
-
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2
-
Smogorzewska, A., Karlseder, J., Holtgreve-Grez, H., Jauch, A. & de Lange, T. DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2. Curr. Biol. 12, 1635-1644 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 1635-1644
-
-
Smogorzewska, A.1
Karlseder, J.2
Holtgreve-Grez, H.3
Jauch, A.4
De Lange, T.5
-
121
-
-
0036839642
-
Subnuclear localization of Ku protein: Functional association with RNA polymerase II elongation sites
-
Mo, X. & Dynan, W. S. Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites. Mol. Cell. Biol. 22, 8088-8099 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8088-8099
-
-
Mo, X.1
Dynan, W.S.2
-
122
-
-
0035805545
-
Distinct roles for Ku protein in transcriptional reinitiation and DNA repair
-
Woodard, R. L., Lee, K., Huang, J. & Dynan, W. S. Distinct roles for Ku protein in transcriptional reinitiation and DNA repair. J. Biol. Chem. 276, 15423-15433 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15423-15433
-
-
Woodard, R.L.1
Lee, K.2
Huang, J.3
Dynan, W.S.4
-
123
-
-
0028855064
-
DNA-dependent protein kinase: A potent inhibitor of transcription by RNA polymerase I
-
Kuhn, A., Gottleib, T. M., Jackson, S. P. & Grummt, I. DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I. Genes Dev. 9, 193-203 (1995).
-
(1995)
Genes Dev.
, vol.9
, pp. 193-203
-
-
Kuhn, A.1
Gottleib, T.M.2
Jackson, S.P.3
Grummt, I.4
-
124
-
-
0036152242
-
Mechanism and control of class-switch recombination
-
Manis, J., Tian, M. & Alt, F. W. Mechanism and control of class-switch recombination. Trends Immunol. 23, 31-39 (2002).
-
(2002)
Trends Immunol.
, vol.23
, pp. 31-39
-
-
Manis, J.1
Tian, M.2
Alt, F.W.3
-
125
-
-
0038713344
-
Immunity through DNA deamination
-
Neuberger, M. S., Harris, R. S., Di Noia, J. & Petersen-Mahrt, S. K. Immunity through DNA deamination. Trends Biochem. Sci. 28, 305-312 (2003).
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 305-312
-
-
Neuberger, M.S.1
Harris, R.S.2
Di Noia, J.3
Petersen-Mahrt, S.K.4
|