DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells

DNA Repair

Volumn 21, Issue , 2014, Pages 97-110

  Oh, Sehyun ^a,b   Harvey, Adam ^a,c   Zimbric, Jacob ^a,d   Wang, Yongbao ^a   Nguyen, Thanh ^a   Jackson, Pauline J ^a   Hendrickson, Eric A ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c Cancer Diagnostics Service Quest Diagnostics Nichols Department of Microbiology and Immunology Columbia Uni versity ^*  (United States)

^d QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

Author keywords

A NHEJ; C NHEJ; Double strand break repair; Gene targeting; Homologous recombination; Ku; Ligase III; Ligase IV; Non homologous end joining

Indexed keywords

ANTIBIOTIC G 418; COMPLEMENTARY DNA; CRE RECOMBINASE; DNA LIGASE III; DNA LIGASE IV; ETOPOSIDE; GENOMIC DNA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; METHYL METHANE SULFONATE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SULFONIC ACID DERIVATIVE; TAMOXIFEN; UNCLASSIFIED DRUG; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; DNA LIGASE (ATP); KU ANTIGEN;

AGAR GEL ELECTROPHORESIS; ARTICLE; CELL SURVIVAL; DNA END JOINING REPAIR; EXON; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE ACTIVITY; GENE CONSTRUCT; GENE TARGETING; GENOTYPE; GROWTH RETARDATION; HCT116 CELL LINE; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; MITOCHONDRION; NULL CELL; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATIC CELL; SOMATIC CELL GENETICS; TISSUE CULTURE; CELL LINE; GENETICS; METABOLISM;

MAMMALIA;

ANTIGENS, NUCLEAR; CELL LINE; DNA END-JOINING REPAIR; DNA LIGASES; DNA-BINDING PROTEINS; HCT116 CELLS; HUMANS;

EID: 84905370561     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2014.04.015     Document Type: Article

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