메뉴 건너뛰기




Volumn 8, Issue 3, 2013, Pages

DNA Ligases I and III Cooperate in Alternative Non-Homologous End-Joining in Vertebrates

Author keywords

[No Author keywords available]

Indexed keywords

DNA LIGASE I; DNA LIGASE II; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG;

EID: 84875484920     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059505     Document Type: Article
Times cited : (66)

References (46)
  • 1
    • 77953229115 scopus 로고    scopus 로고
    • The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
    • Lieber MR, (2010) The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway. Annual Review of Biochemistry 79: 1.1-1.31.
    • (2010) Annual Review of Biochemistry , vol.79 , pp. 1-31
    • Lieber, M.R.1
  • 2
    • 79956215808 scopus 로고    scopus 로고
    • Induction and Repair of DNA Double Strand Breaks: The Increasing Spectrum of Non-homologous End Joining Pathways
    • Mladenov E, Iliakis G, (2011) Induction and Repair of DNA Double Strand Breaks: The Increasing Spectrum of Non-homologous End Joining Pathways. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 711: 61-72.
    • (2011) Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis , vol.711 , pp. 61-72
    • Mladenov, E.1    Iliakis, G.2
  • 3
    • 54849404458 scopus 로고    scopus 로고
    • MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings
    • McVey M, Lee SE, (2008) MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. Trends in Genetics 24: 529-538.
    • (2008) Trends in Genetics , vol.24 , pp. 529-538
    • McVey, M.1    Lee, S.E.2
  • 4
    • 59849089955 scopus 로고    scopus 로고
    • Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
    • Mahaney BL, Meek K, Lees-Miller SP, (2009) Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochemical Journal 417: 639-650.
    • (2009) Biochemical Journal , vol.417 , pp. 639-650
    • Mahaney, B.L.1    Meek, K.2    Lees-Miller, S.P.3
  • 5
    • 0034162719 scopus 로고    scopus 로고
    • DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus
    • DiBiase SJ, Zeng Z-C, Chen R, Hyslop T, Curran WJ, et al. (2000) DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus. Cancer Research 60: 1245-1253.
    • (2000) Cancer Research , vol.60 , pp. 1245-1253
    • DiBiase, S.J.1    Zeng, Z.-C.2    Chen, R.3    Hyslop, T.4    Curran, W.J.5
  • 6
    • 55249116558 scopus 로고    scopus 로고
    • γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
    • Kinner A, Wu W, Staudt C, Iliakis G, (2008) γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin. Nucleic Acids Research 36: 5678-5694.
    • (2008) Nucleic Acids Research , vol.36 , pp. 5678-5694
    • Kinner, A.1    Wu, W.2    Staudt, C.3    Iliakis, G.4
  • 9
    • 84860172038 scopus 로고    scopus 로고
    • Backup Pathways of Nonhomologous End Joining May Have a Dominant Role in the Formation of Chromosome Aberrations
    • Obe G, Vijayalaxmi, editor, Berlin, Heidelberg, New York: Springer Verlag
    • Iliakis G, Wu W, Wang M, Terzoudi GI, Pantelias GE (2007) Backup Pathways of Nonhomologous End Joining May Have a Dominant Role in the Formation of Chromosome Aberrations. In: Obe G, Vijayalaxmi, editor. Chromosomal Alterations. Berlin, Heidelberg, New York: Springer Verlag. 67-85.
    • (2007) Chromosomal Alterations , pp. 67-85
    • Iliakis, G.1    Wu, W.2    Wang, M.3    Terzoudi, G.I.4    Pantelias, G.E.5
  • 11
    • 78650995499 scopus 로고    scopus 로고
    • An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
    • Zhang Y, Jasin M, (2011) An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway. Nature Structural & Molecular Biology 18: 80-84.
    • (2011) Nature Structural & Molecular Biology , vol.18 , pp. 80-84
    • Zhang, Y.1    Jasin, M.2
  • 12
    • 80655140620 scopus 로고    scopus 로고
    • DNA ligase III: A spotty presence in eukaryotes, but an essential function where tested
    • Simsek D, Jasin M, (2011) DNA ligase III: A spotty presence in eukaryotes, but an essential function where tested. Cell Cycle 10: 3636-3644.
    • (2011) Cell Cycle , vol.10 , pp. 3636-3644
    • Simsek, D.1    Jasin, M.2
  • 13
    • 79959814259 scopus 로고    scopus 로고
    • DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation
    • Simsek D, Brunet E, Wong SY-W, Katyal S, Gao Y, et al. (2011) DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation. PLoS Genetics 7: e1002080.
    • (2011) PLoS Genetics , vol.7
    • Simsek, D.1    Brunet, E.2    Wong, S.Y.-W.3    Katyal, S.4    Gao, Y.5
  • 14
    • 79952368682 scopus 로고    scopus 로고
    • DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair
    • Gao Y, Katyal S, Lee Y, Zhao J, Rehg JE, et al. (2011) DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair. Nature 471: 240-244.
    • (2011) Nature , vol.471 , pp. 240-244
    • Gao, Y.1    Katyal, S.2    Lee, Y.3    Zhao, J.4    Rehg, J.E.5
  • 15
    • 79952426030 scopus 로고    scopus 로고
    • Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair
    • Simsek D, Furda A, Gao Y, Artus J, Brunet E, et al. (2011) Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature 471: 245-248.
    • (2011) Nature , vol.471 , pp. 245-248
    • Simsek, D.1    Furda, A.2    Gao, Y.3    Artus, J.4    Brunet, E.5
  • 17
    • 45549094090 scopus 로고    scopus 로고
    • Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks
    • Liang L, Deng L, Nguyen SC, Zhao X, Maulion CD, et al. (2008) Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks. Nucleic Acids Research 36: 3297-3310.
    • (2008) Nucleic Acids Research , vol.36 , pp. 3297-3310
    • Liang, L.1    Deng, L.2    Nguyen, S.C.3    Zhao, X.4    Maulion, C.D.5
  • 18
    • 84859336816 scopus 로고    scopus 로고
    • Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells
    • Arakawa H, Bednar T, Wang M, Paul K, Mladenov E, et al. (2012) Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells. Nucleic Acids Research 40: 2599-2610.
    • (2012) Nucleic Acids Research , vol.40 , pp. 2599-2610
    • Arakawa, H.1    Bednar, T.2    Wang, M.3    Paul, K.4    Mladenov, E.5
  • 19
    • 0025739820 scopus 로고
    • Kinetics of DNA double strand breaks throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells
    • Metzger L, Iliakis G, (1991) Kinetics of DNA double strand breaks throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells. International Journal of Radiation Biology 59: 1325-1339.
    • (1991) International Journal of Radiation Biology , vol.59 , pp. 1325-1339
    • Metzger, L.1    Iliakis, G.2
  • 20
    • 37549006429 scopus 로고    scopus 로고
    • Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2
    • Wu W, Wang M, Wu W, Singh SK, Mussfeldt T, et al. (2008) Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2. DNA Repair 7: 329-338.
    • (2008) DNA Repair , vol.7 , pp. 329-338
    • Wu, W.1    Wang, M.2    Wu, W.3    Singh, S.K.4    Mussfeldt, T.5
  • 21
    • 55249102702 scopus 로고    scopus 로고
    • Enhanced Use of Backup Pathways of NHEJ in G2 in Chinese Hamster Mutant Cells with Defects in the Classical Pathway of NHEJ
    • Wu W, Wang M, Mussfeldt T, Iliakis G, (2008) Enhanced Use of Backup Pathways of NHEJ in G2 in Chinese Hamster Mutant Cells with Defects in the Classical Pathway of NHEJ. Radiation Research 170: 512-520.
    • (2008) Radiation Research , vol.170 , pp. 512-520
    • Wu, W.1    Wang, M.2    Mussfeldt, T.3    Iliakis, G.4
  • 22
    • 69949173301 scopus 로고    scopus 로고
    • Backup pathways of NHEJ in cells of higher eukaryotes: Cell cycle dependence
    • Iliakis G, (2009) Backup pathways of NHEJ in cells of higher eukaryotes: Cell cycle dependence. Radiotherapy and Oncology 92: 310-315.
    • (2009) Radiotherapy and Oncology , vol.92 , pp. 310-315
    • Iliakis, G.1
  • 23
    • 0035953402 scopus 로고    scopus 로고
    • Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group
    • Wang H, Zeng Z-C, Bui T-A, Sonoda E, Takata M, et al. (2001) Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group. Oncogene 20: 2212-2224.
    • (2001) Oncogene , vol.20 , pp. 2212-2224
    • Wang, H.1    Zeng, Z.-C.2    Bui, T.-A.3    Sonoda, E.4    Takata, M.5
  • 24
    • 77953166592 scopus 로고    scopus 로고
    • γH2AX foci analysis for monitoring DNA double-strand break repair - Strengths, limitations and optimization
    • Löbrich M, Shibata A, Beucher A, Fisher A, Ensminger M, et al. (2010) γH2AX foci analysis for monitoring DNA double-strand break repair- Strengths, limitations and optimization. Cell Cycle 9: 662-669.
    • (2010) Cell Cycle , vol.9 , pp. 662-669
    • Löbrich, M.1    Shibata, A.2    Beucher, A.3    Fisher, A.4    Ensminger, M.5
  • 26
    • 0025330664 scopus 로고
    • Mammalian DNA ligases. Biosynthesis and Intracellular Localization of DNA Ligase I
    • Lasko DD, Tomkinson AE, Lindahl T, (1990) Mammalian DNA ligases. Biosynthesis and intracellular localization of DNA ligase I. Journal of Biological Chemistry 265: 12618-12622.
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 12618-12622
    • Lasko, D.D.1    Tomkinson, A.E.2    Lindahl, T.3
  • 27
    • 48249095920 scopus 로고    scopus 로고
    • Single-strand break repair and genetic disease
    • Caldecott KW, (2008) Single-strand break repair and genetic disease. Nature Reviews Genetics 9: 619-631.
    • (2008) Nature Reviews Genetics , vol.9 , pp. 619-631
    • Caldecott, K.W.1
  • 28
    • 34848828539 scopus 로고    scopus 로고
    • Low Levels of DNA Ligases III and IV Sufficient for Effective NHEJ
    • Windhofer F, Wu W, Iliakis G, (2007) Low Levels of DNA Ligases III and IV Sufficient for Effective NHEJ. Journal of Cellular Physiology 213: 475-483.
    • (2007) Journal of Cellular Physiology , vol.213 , pp. 475-483
    • Windhofer, F.1    Wu, W.2    Iliakis, G.3
  • 29
    • 0035870583 scopus 로고    scopus 로고
    • Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells
    • Wang H, Zhao-Chong Z, Perrault AR, Cheng X, Qin W, et al. (2001) Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells. Nucleic Acids Research 29: 1653-1660.
    • (2001) Nucleic Acids Research , vol.29 , pp. 1653-1660
    • Wang, H.1    Zhao-Chong, Z.2    Perrault, A.R.3    Cheng, X.4    Qin, W.5
  • 30
    • 20144363082 scopus 로고    scopus 로고
    • DNA Ligase III as a Candidate Component of Backup Pathways of Nonhomologous End Joining
    • Wang H, Rosidi B, Perrault R, Wang M, Zhang L, et al. (2005) DNA Ligase III as a Candidate Component of Backup Pathways of Nonhomologous End Joining. Cancer Research 65: 4020-4030.
    • (2005) Cancer Research , vol.65 , pp. 4020-4030
    • Wang, H.1    Rosidi, B.2    Perrault, R.3    Wang, M.4    Zhang, L.5
  • 31
    • 77954824233 scopus 로고    scopus 로고
    • Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States
    • Cotner-Gohara E, Kim I-K, Hammel M, Tainer JA, Tomkinson AE, et al. (2010) Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States. Biochemistry 49: 6165-6176.
    • (2010) Biochemistry , vol.49 , pp. 6165-6176
    • Cotner-Gohara, E.1    Kim, I.-K.2    Hammel, M.3    Tainer, J.A.4    Tomkinson, A.E.5
  • 32
    • 0033618289 scopus 로고    scopus 로고
    • DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly (ADP-ribose) Polymerase
    • Mackey ZB, Niedergang C, Menissier-de Murcia J, Leppard J, Au K, et al. (1999) DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly (ADP-ribose) Polymerase. Journal of Biological Chemistry 274: 21679-21687.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 21679-21687
    • Mackey, Z.B.1    Niedergang, C.2    Menissier-de Murcia, J.3    Leppard, J.4    Au, K.5
  • 33
    • 0000391880 scopus 로고    scopus 로고
    • Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle
    • Lee SE, Mitchell RA, Cheng A, Hendrickson EA, (1997) Evidence for DNA-PK-dependent and-independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle. Molecular and Cellular Biology 17: 1425-1433.
    • (1997) Molecular and Cellular Biology , vol.17 , pp. 1425-1433
    • Lee, S.E.1    Mitchell, R.A.2    Cheng, A.3    Hendrickson, E.A.4
  • 34
    • 0032916940 scopus 로고    scopus 로고
    • Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks
    • Chernikova SB, Wells RL, Elkind MM, (1999) Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks. Radiation Research 151: 159-166.
    • (1999) Radiation Research , vol.151 , pp. 159-166
    • Chernikova, S.B.1    Wells, R.L.2    Elkind, M.M.3
  • 35
    • 11244280890 scopus 로고    scopus 로고
    • Involvement of Poly(ADP-ribose) Polymerase-1 and XRCC1/DNA Ligase III in an Alternative Route for DNA Double-strand Breaks Rejoining
    • Audebert M, Salles B, Calsou P, (2004) Involvement of Poly(ADP-ribose) Polymerase-1 and XRCC1/DNA Ligase III in an Alternative Route for DNA Double-strand Breaks Rejoining. Journal of Biological Chemistry 279: 55117-55126.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 55117-55126
    • Audebert, M.1    Salles, B.2    Calsou, P.3
  • 36
    • 41149176120 scopus 로고    scopus 로고
    • Histone H1 functions as a stimulatory factor in backup pathways of NHEJ
    • Rosidi B, Wang M, Wu W, Sharma A, Wang H, et al. (2008) Histone H1 functions as a stimulatory factor in backup pathways of NHEJ. Nucleic Acids Research 36: 1610-1623.
    • (2008) Nucleic Acids Research , vol.36 , pp. 1610-1623
    • Rosidi, B.1    Wang, M.2    Wu, W.3    Sharma, A.4    Wang, H.5
  • 37
    • 33845657443 scopus 로고    scopus 로고
    • PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
    • Wang M, Wu W, Wu W, Rosidi B, Zhang L, et al. (2006) PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways. Nucleic Acids Research 34: 6170-6182.
    • (2006) Nucleic Acids Research , vol.34 , pp. 6170-6182
    • Wang, M.1    Wu, W.2    Wu, W.3    Rosidi, B.4    Zhang, L.5
  • 38
    • 51649128895 scopus 로고    scopus 로고
    • Up-regulation of WRN and DNA ligase IIIα in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks
    • Sallmyr A, Tomkinson AE, Rassool FV, (2008) Up-regulation of WRN and DNA ligase IIIα in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks. Blood 112: 1413-1423.
    • (2008) Blood , vol.112 , pp. 1413-1423
    • Sallmyr, A.1    Tomkinson, A.E.2    Rassool, F.V.3
  • 39
    • 0041378046 scopus 로고    scopus 로고
    • XRCC1 and DNA strand break repair
    • Caldecott KW, (2003) XRCC1 and DNA strand break repair. DNA Repair 2: 955-969.
    • (2003) DNA Repair , vol.2 , pp. 955-969
    • Caldecott, K.W.1
  • 41
    • 0029791694 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone repair pathways
    • Boulton SJ, Jackson SP, (1996) Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone repair pathways. EMBO Journal 15: 5093-5103.
    • (1996) EMBO Journal , vol.15 , pp. 5093-5103
    • Boulton, S.J.1    Jackson, S.P.2
  • 42
    • 0242468933 scopus 로고    scopus 로고
    • Yeast Mre11 and Rad1 Proteins Define a Ku-Independent Mechanism To Repair Double-Strand Breaks Lacking Overlapping End Sequences
    • Ma J-L, Kim EM, Haber JE, Lee SE, (2003) Yeast Mre11 and Rad1 Proteins Define a Ku-Independent Mechanism To Repair Double-Strand Breaks Lacking Overlapping End Sequences. Molecular and Cellular Biology 23: 8820-8828.
    • (2003) Molecular and Cellular Biology , vol.23 , pp. 8820-8828
    • Ma, J.-L.1    Kim, E.M.2    Haber, J.E.3    Lee, S.E.4
  • 43
    • 34548401682 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Sae2- and Tel1-Dependent Single-Strand DNA Formation at DNA Break Promotes Microhomology-Mediated End Joining
    • Lee K, Lee SE, (2007) Saccharomyces cerevisiae Sae2- and Tel1-Dependent Single-Strand DNA Formation at DNA Break Promotes Microhomology-Mediated End Joining. Genetics 176: 2003-2014.
    • (2007) Genetics , vol.176 , pp. 2003-2014
    • Lee, K.1    Lee, S.E.2
  • 44
    • 3042559648 scopus 로고    scopus 로고
    • Mutant lox P vectors for selectable marker recycle and conditional knockouts
    • Arakawa H, Lodygin D, Buerstedde J-M, (2001) Mutant lox P vectors for selectable marker recycle and conditional knockouts. BMC Biotechnology 1: 7.
    • (2001) BMC Biotechnology , vol.1 , pp. 7
    • Arakawa, H.1    Lodygin, D.2    Buerstedde, J.-M.3
  • 45
    • 0037083364 scopus 로고    scopus 로고
    • Requirement of the Activation-Induced Deaminase (AID) Gene for Immunoglobulin Gene Conversion
    • Arakawa H, Hauschild J, Buerstedde J-M, (2002) Requirement of the Activation-Induced Deaminase (AID) Gene for Immunoglobulin Gene Conversion. Science 295: 1301-1306.
    • (2002) Science , vol.295 , pp. 1301-1306
    • Arakawa, H.1    Hauschild, J.2    Buerstedde, J.-M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.