메뉴 건너뛰기




Volumn 17, Issue 18, 1998, Pages 5497-5508

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

Author keywords

Homologous recombination; Ku; Non homologous end joining; Rad54; Spontaneous chromosomal break

Indexed keywords

DOUBLE STRANDED DNA;

EID: 0032530658     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.18.5497     Document Type: Article
Times cited : (1047)

References (78)
  • 1
    • 0021972902 scopus 로고
    • Cell lines derived from avian lymphomas exhibit two distinct phenotypes
    • Baba, T.W., Giroir, B.P. and Humphries, E.H. (1985) Cell lines derived from avian lymphomas exhibit two distinct phenotypes. Virology, 144, 139-151.
    • (1985) Virology , vol.144 , pp. 139-151
    • Baba, T.W.1    Giroir, B.P.2    Humphries, E.H.3
  • 2
    • 0025945665 scopus 로고
    • A system for assaying homologous recombination at the endogenous human thymidine kinase gene
    • Benjamin, M.B., Potter, H., Yandell, D.W. and Little, J.B. (1991) A system for assaying homologous recombination at the endogenous human thymidine kinase gene. Proc. Natl Acad. Sci. USA, 88, 6652-6656.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 6652-6656
    • Benjamin, M.B.1    Potter, H.2    Yandell, D.W.3    Little, J.B.4
  • 3
    • 0028208636 scopus 로고
    • Gene conversion in the chicken immunoglobulin locus: A paradigm of homologous recombination in higher eukaryotes
    • Bezzubova, O.Y. and Buerstedde, J.M. (1994) Gene conversion in the chicken immunoglobulin locus: a paradigm of homologous recombination in higher eukaryotes. Experientia, 50, 270-276.
    • (1994) Experientia , vol.50 , pp. 270-276
    • Bezzubova, O.Y.1    Buerstedde, J.M.2
  • 4
    • 0027243832 scopus 로고
    • A chicken RAD51 homologue is expressed at high levels in lymphoid and reproductive organs
    • Bezzubova, O., Shinohara, A., Mueller, R.G., Ogawa, H. and Buerstedde, J.M. (1993a) A chicken RAD51 homologue is expressed at high levels in lymphoid and reproductive organs. Nucleic Acids Res., 21, 1577-1580.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1577-1580
    • Bezzubova, O.1    Shinohara, A.2    Mueller, R.G.3    Ogawa, H.4    Buerstedde, J.M.5
  • 5
    • 0027722245 scopus 로고
    • Identification of a chicken RAD52 homologue suggests conservation of the RAD52 recombination pathway throughout the evolution of higher eukaryotes
    • Bezzubova, O.Y., Schmidt, H., Ostermann, K., Heyer, W.D. and Buerstedde, J.M. (1993b) Identification of a chicken RAD52 homologue suggests conservation of the RAD52 recombination pathway throughout the evolution of higher eukaryotes. Nucleic Acids Res., 21, 5945-5949.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5945-5949
    • Bezzubova, O.Y.1    Schmidt, H.2    Ostermann, K.3    Heyer, W.D.4    Buerstedde, J.M.5
  • 7
    • 0029843408 scopus 로고    scopus 로고
    • Identification of a Saccharomyces cerevisiae Ku80 homologue: Roles in DNA double strand break rejoining and in telomeric maintenance
    • Boulton, S.J. and Jackson, S.P. (1996a) Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res., 24, 4639-4648.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4639-4648
    • Boulton, S.J.1    Jackson, S.P.2
  • 8
    • 0029791694 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
    • Boulton, S.J. and Jackson, S.P. (1996b) Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J., 15, 5093-5103.
    • (1996) EMBO J. , vol.15 , pp. 5093-5103
    • Boulton, S.J.1    Jackson, S.P.2
  • 9
    • 0025936509 scopus 로고
    • Increased ratio of targeted to random integration after transfection of chicken B cell lines
    • Buerstedde, J.M. and Takeda, S. (1991) Increased ratio of targeted to random integration after transfection of chicken B cell lines. Cell, 67, 179-188.
    • (1991) Cell , vol.67 , pp. 179-188
    • Buerstedde, J.M.1    Takeda, S.2
  • 11
    • 0028366253 scopus 로고
    • Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays
    • Cheong, N., Wang, X., Wang, Y. and Iliakis, G. (1994) Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays. Mutat. Res., 314, 77-85.
    • (1994) Mutat. Res. , vol.314 , pp. 77-85
    • Cheong, N.1    Wang, X.2    Wang, Y.3    Iliakis, G.4
  • 12
    • 0031214080 scopus 로고    scopus 로고
    • Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV
    • Critchlow, S.E., Bowater, R.P. and Jackson, S.P. (1997) Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr. Biol., 7, 588-598.
    • (1997) Curr. Biol. , vol.7 , pp. 588-598
    • Critchlow, S.E.1    Bowater, R.P.2    Jackson, S.P.3
  • 13
    • 0023110664 scopus 로고
    • Cytological characterization of Chinese hamster ovary X-ray-sensitive mutant cells, xrs 5 and xrs 6. II. Induction of sister-chromatid exchanges and chromosomal aberrations by X-rays and UV-irradiation and their modulation by inhibitors of poly (ADP-ribose) synthetase and α-polymerase
    • Darroudi, F. and Natarajan, A.T. (1987) Cytological characterization of Chinese hamster ovary X-ray-sensitive mutant cells, xrs 5 and xrs 6. II. Induction of sister-chromatid exchanges and chromosomal aberrations by X-rays and UV-irradiation and their modulation by inhibitors of poly (ADP-ribose) synthetase and α-polymerase. Mutat. Res., 177, 149-160.
    • (1987) Mutat. Res. , vol.177 , pp. 149-160
    • Darroudi, F.1    Natarajan, A.T.2
  • 15
    • 0027288231 scopus 로고
    • A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae
    • Feldmann, H. and Winnacker, E.L. (1993) A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae. J. Biol. Chem., 268, 12895-12900.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12895-12900
    • Feldmann, H.1    Winnacker, E.L.2
  • 16
    • 0021328020 scopus 로고
    • Cell cycle parameters in radiation sensitive strains of Saccharomyces cerevisiae
    • Fingerhut, R., Kiefer, J. and Otto, F. (1984) Cell cycle parameters in radiation sensitive strains of Saccharomyces cerevisiae. Mol. Gen. Genet., 193, 192-194.
    • (1984) Mol. Gen. Genet. , vol.193 , pp. 192-194
    • Fingerhut, R.1    Kiefer, J.2    Otto, F.3
  • 17
    • 0027587771 scopus 로고
    • DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces
    • Game, J.C. (1993) DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces. Semin. Cancer Biol., 4, 73-83.
    • (1993) Semin. Cancer Biol. , vol.4 , pp. 73-83
    • Game, J.C.1
  • 18
    • 0016274036 scopus 로고
    • A genetic study of X-ray sensitive mutants in yeast
    • Game, J.C. and Mortimer, R.K. (1974) A genetic study of X-ray sensitive mutants in yeast. Mutat. Res., 24, 281-292.
    • (1974) Mutat. Res. , vol.24 , pp. 281-292
    • Game, J.C.1    Mortimer, R.K.2
  • 19
    • 0027955773 scopus 로고
    • Cloning and expression of the murine homologue of a putative human X-linked nuclear protein gene closely linked to PGK1 in Xq13.3
    • Gecz, J., Pollard, H., Consalez, G., Villard, L., Stayton, C., Millasseau, P. Khrestchatisky, M. and Fontes, M. (1994) Cloning and expression of the murine homologue of a putative human X-linked nuclear protein gene closely linked to PGK1 in Xq13.3. Hum. Mol. Genet., 3, 39-44.
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 39-44
    • Gecz, J.1    Pollard, H.2    Consalez, G.3    Villard, L.4    Stayton, C.5    Millasseau, P.6    Khrestchatisky, M.7    Fontes, M.8
  • 20
    • 0028577296 scopus 로고
    • Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells
    • Godwin, A.R., Bollag, R.J., Christie, D.M. and Liskay, R.M. (1994) Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells. Proc. Natl Acad. Sci. USA, 91, 12554-12558.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 12554-12558
    • Godwin, A.R.1    Bollag, R.J.2    Christie, D.M.3    Liskay, R.M.4
  • 21
    • 0030743386 scopus 로고    scopus 로고
    • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
    • Grawunder, U., Wilm, M., Wu, X., Kulesza, P., Wilson, T.E., Mann, M. and Lieber, M.R. (1997) Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature, 388, 492-495.
    • (1997) Nature , vol.388 , pp. 492-495
    • Grawunder, U.1    Wilm, M.2    Wu, X.3    Kulesza, P.4    Wilson, T.E.5    Mann, M.6    Lieber, M.R.7
  • 22
    • 0030858967 scopus 로고    scopus 로고
    • Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity and inability to support V(D)J recombination
    • Gu, Y., Jin, S., Gao, Y., Weaver, D.T. and Alt, F.W. (1997) Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity and inability to support V(D)J recombination. Proc. Natl Acad. Sci. USA, 94, 8076-8081.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 8076-8081
    • Gu, Y.1    Jin, S.2    Gao, Y.3    Weaver, D.T.4    Alt, F.W.5
  • 23
    • 0030886602 scopus 로고    scopus 로고
    • A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae
    • Guacci, V., Koshland, D. and Strunnikov, A. (1997) A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae. Cell, 91, 47-57.
    • (1997) Cell , vol.91 , pp. 47-57
    • Guacci, V.1    Koshland, D.2    Strunnikov, A.3
  • 24
    • 0003592020 scopus 로고
    • Report of the Standing Commitee on Human Cytogenetic Nomenclature. Karger, Basel, Switzerland
    • ISCN1985 (1985) An International System for Human Cytogenetic Nomenclature. Report of the Standing Commitee on Human Cytogenetic Nomenclature. Karger, Basel, Switzerland.
    • (1985) An International System for Human Cytogenetic Nomenclature
  • 25
    • 0025368957 scopus 로고
    • Studies on mammalian mutants defective in rejoining double-strand breaks in DNA
    • Jeggo, P.A. (1990) Studies on mammalian mutants defective in rejoining double-strand breaks in DNA. Mutat. Res., 239, 1-16.
    • (1990) Mutat. Res. , vol.239 , pp. 1-16
    • Jeggo, P.A.1
  • 26
    • 0030922250 scopus 로고    scopus 로고
    • DNA-PK: At the cross-roads of biochemistry and genetics
    • Jeggo, P.A. (1997) DNA-PK: at the cross-roads of biochemistry and genetics. Mutat. Res., 384, 1-14.
    • (1997) Mutat. Res. , vol.384 , pp. 1-14
    • Jeggo, P.A.1
  • 27
    • 0026709385 scopus 로고
    • Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae
    • Kadyk, L.C. and Hartwell, L.H. (1992) Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae. Genetics, 132, 387-402.
    • (1992) Genetics , vol.132 , pp. 387-402
    • Kadyk, L.C.1    Hartwell, L.H.2
  • 28
    • 16044374874 scopus 로고    scopus 로고
    • Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: Evidence for functional conservation
    • Kanaar, R. et al. (1996) Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation. Curr. Biol., 6. 828-838.
    • (1996) Curr. Biol. , vol.6 , pp. 828-838
    • Kanaar, R.1
  • 29
    • 0022968662 scopus 로고
    • Radiation-induced chromosome damage in X-ray-sensitive mutants (xrs) of the Chinese hamster ovary cell line
    • Kemp, L.M. and Jeggo, P.A. (1986) Radiation-induced chromosome damage in X-ray-sensitive mutants (xrs) of the Chinese hamster ovary cell line. Mutat. Res., 166, 255-263.
    • (1986) Mutat. Res. , vol.166 , pp. 255-263
    • Kemp, L.M.1    Jeggo, P.A.2
  • 30
    • 0023054773 scopus 로고
    • Bifunctional messenger RNAs in eukaryotes
    • Kozak, M. (1986) Bifunctional messenger RNAs in eukaryotes. Cell, 47, 481-483.
    • (1986) Cell , vol.47 , pp. 481-483
    • Kozak, M.1
  • 31
    • 0028914004 scopus 로고
    • Adherence to the first-AUG rule when a second AUG codon follows closely upon the first
    • Published erratum appears in Proc. Natl Acad. Sci. USA, 92, 7134
    • Kozak, M. (1995) Adherence to the first-AUG rule when a second AUG codon follows closely upon the first. [Published erratum appears in Proc. Natl Acad. Sci. USA, 92, 7134]. Proc. Natl Acad. Sci. USA, 92, 2662-2666.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 2662-2666
    • Kozak, M.1
  • 32
    • 0000391880 scopus 로고    scopus 로고
    • Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle
    • Lee, S.E., Mitchell, R.A., Cheng, A. and Hendrickson, E.A. (1997) Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle. Mol. Cell. Biol., 17, 1425-1433.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1425-1433
    • Lee, S.E.1    Mitchell, R.A.2    Cheng, A.3    Hendrickson, E.A.4
  • 33
    • 0029585872 scopus 로고
    • The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
    • Li, Z., Otevrel, T., Gao, Y., Cheng, H.L., Seed, B., Stamato, T.D., Taccioli, G.E. and Alt, F.W. (1995) The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell, 83, 1079-1089.
    • (1995) Cell , vol.83 , pp. 1079-1089
    • Li, Z.1    Otevrel, T.2    Gao, Y.3    Cheng, H.L.4    Seed, B.5    Stamato, T.D.6    Taccioli, G.E.7    Alt, F.W.8
  • 34
    • 0029909565 scopus 로고    scopus 로고
    • A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53
    • Lim, D.-S. and Hasty, P. (1996) A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol. Cell. Biol., 16, 7133-7143.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 7133-7143
    • Lim, D.-S.1    Hasty, P.2
  • 35
    • 0032061317 scopus 로고    scopus 로고
    • XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA crosslinks and other damages
    • Liu, N. et al. (1998) XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA crosslinks and other damages. Mol. Cell, 1, 783-793.
    • (1998) Mol. Cell , vol.1 , pp. 783-793
    • Liu, N.1
  • 36
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin, S.J., Reutelingsperger, C.P., McGahon, A.J., Rader, J.A., van-Schie, R.C., LaFace, D.M. and Green, D.R. (1995) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med., 182, 1545-1556.
    • (1995) J. Exp. Med. , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingsperger, C.P.2    McGahon, A.J.3    Rader, J.A.4    Van-Schie, R.C.5    LaFace, D.M.6    Green, D.R.7
  • 37
    • 0030885925 scopus 로고    scopus 로고
    • Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
    • Michaelis, C., Ciosk, R. and Nasmyth, K. (1997) Cohesins: chromosomal proteins that prevent premature separation of sister chromatids. Cell, 91, 35-45.
    • (1997) Cell , vol.91 , pp. 35-45
    • Michaelis, C.1    Ciosk, R.2    Nasmyth, K.3
  • 38
    • 0029954821 scopus 로고    scopus 로고
    • Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
    • Milne, G.T., Jin, S., Shannon, K.B. and Weaver, D.T. (1996) Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol., 16, 4189-4198.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4189-4198
    • Milne, G.T.1    Jin, S.2    Shannon, K.B.3    Weaver, D.T.4
  • 39
    • 0022827675 scopus 로고
    • Mechanism of interaction between Ku protein and DNA
    • Mimori, T. and Hardin, J.A. (1986) Mechanism of interaction between Ku protein and DNA. J. Biol. Chem., 261, 10375-10379.
    • (1986) J. Biol. Chem. , vol.261 , pp. 10375-10379
    • Mimori, T.1    Hardin, J.A.2
  • 40
    • 0025216073 scopus 로고
    • Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome
    • Mimori, T., Ohosone, Y., Hama, N., Suwa, A., Akizuki, M., Homma, M., Griffith, A.J. and Hardin, J.A. (1990) Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome. Proc. Natl. Acad. Sci. USA, 87, 1777-1781.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1777-1781
    • Mimori, T.1    Ohosone, Y.2    Hama, N.3    Suwa, A.4    Akizuki, M.5    Homma, M.6    Griffith, A.J.7    Hardin, J.A.8
  • 42
    • 0029976325 scopus 로고    scopus 로고
    • Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
    • Moore, J.K. and Haber, J.E. (1996) Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol., 16, 2164-2173.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2164-2173
    • Moore, J.K.1    Haber, J.E.2
  • 44
    • 0030797563 scopus 로고    scopus 로고
    • Loss of heterozygosity induced by a chromosomal double-strand break
    • Moynahan, M.E. and Jasin, M. (1997) Loss of heterozygosity induced by a chromosomal double-strand break. Proc. Natl Acad. Sci. USA, 94, 8988-8993.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 8988-8993
    • Moynahan, M.E.1    Jasin, M.2
  • 46
    • 0030043199 scopus 로고    scopus 로고
    • Isolation of the Schizosaccharomyces pombe RAD54 homologue, rhp54+, a gene involved in the repair of radiation damage and replication fidelity
    • Muris, D.F.R., Vreeken, K., Carr, A.M., Murray, J.M., Smit, C., Lohman, P.H.M. and Pastink, A. (1996) Isolation of the Schizosaccharomyces pombe RAD54 homologue, rhp54+, a gene involved in the repair of radiation damage and replication fidelity. J. Cell Sci., 109, 73-81.
    • (1996) J. Cell Sci. , vol.109 , pp. 73-81
    • Muris, D.F.R.1    Vreeken, K.2    Carr, A.M.3    Murray, J.M.4    Smit, C.5    Lohman, P.H.M.6    Pastink, A.7
  • 48
    • 0030885974 scopus 로고    scopus 로고
    • Ku70 is required for DNA repair but not for T cell receptor gene recombination in vivo
    • Ouyang, H. et al. (1997) Ku70 is required for DNA repair but not for T cell receptor gene recombination in vivo. J. Exp. Med., 186, 921-929.
    • (1997) J. Exp. Med. , vol.186 , pp. 921-929
    • Ouyang, H.1
  • 49
    • 0000459439 scopus 로고
    • The molecular and cellular biology of the yeast Saccharomyces
    • Broach, J.R., Pringle, J.R. and Jones, E.W. (eds). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Petes, T.D., Malone, R.E. and Symington, L.S. (1991) The molecular and cellular biology of the yeast Saccharomyces. In Broach, J.R., Pringle, J.R. and Jones, E.W. (eds). Recombination in Yeast. Vol. 1. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 407-522.
    • (1991) Recombination in Yeast , vol.1 , pp. 407-522
    • Petes, T.D.1    Malone, R.E.2    Symington, L.S.3
  • 51
    • 0019172203 scopus 로고
    • Genetic control of diploid recovery after γ-irradiation in the yeast Saccharomyces cerevisiae
    • Saeki, T., Machida, I. and Nakai, S. (1980) Genetic control of diploid recovery after γ-irradiation in the yeast Saccharomyces cerevisiae. Mutat. Res., 73, 251-265.
    • (1980) Mutat. Res. , vol.73 , pp. 251-265
    • Saeki, T.1    Machida, I.2    Nakai, S.3
  • 52
    • 0030034110 scopus 로고    scopus 로고
    • Withdrawal of differentiation inhibitory activity/ leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells
    • Savatier, P., Lapillonne, H., van-Grunsven, L.A., Rudkin, B.B. and Samarut, J. (1996) Withdrawal of differentiation inhibitory activity/ leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Oncogene, 12, 309-322.
    • (1996) Oncogene , vol.12 , pp. 309-322
    • Savatier, P.1    Lapillonne, H.2    Van-Grunsven, L.A.3    Rudkin, B.B.4    Samarut, J.5
  • 54
    • 0030933762 scopus 로고    scopus 로고
    • Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
    • Sharan, S.K. et al. (1997) Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature, 386, 804-810.
    • (1997) Nature , vol.386 , pp. 804-810
    • Sharan, S.K.1
  • 55
    • 0028879965 scopus 로고
    • Homologous recombination and the roles of double-strand breaks
    • Shinohara, A. and Ogawa, T. (1995) Homologous recombination and the roles of double-strand breaks. Trends Biochem. Sci., 20, 387-391.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 387-391
    • Shinohara, A.1    Ogawa, T.2
  • 56
    • 0027325816 scopus 로고
    • Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA
    • Published erratum appears in Nature Genet., 5, 312.
    • Shinohara, A., Ogawa, H., Matsuda, Y., Ushio, N., Ikeo, K. and Ogawa, T. (1993) Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA. [Published erratum appears in Nature Genet., 5, 312]. Nature Genet., 4, 239-243.
    • (1993) Nature Genet. , vol.4 , pp. 239-243
    • Shinohara, A.1    Ogawa, H.2    Matsuda, Y.3    Ushio, N.4    Ikeo, K.5    Ogawa, T.6
  • 57
    • 0028112944 scopus 로고
    • Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA
    • Smider, V., Rathmell, W.K., Lieber, M.R. and Chu, G. (1994) Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science, 266, 288-291.
    • (1994) Science , vol.266 , pp. 288-291
    • Smider, V.1    Rathmell, W.K.2    Lieber, M.R.3    Chu, G.4
  • 59
    • 0023720228 scopus 로고
    • Cell-cycle-dependent repair of potentially lethal damage in the XR-1 γ-ray-sensitive Chinese hamster ovary cell
    • Stamato, T.D., Dipatri, A. and Giaccia, A. (1988) Cell-cycle-dependent repair of potentially lethal damage in the XR-1 γ-ray-sensitive Chinese hamster ovary cell. Radiat. Res., 115. 325-333.
    • (1988) Radiat. Res. , vol.115 , pp. 325-333
    • Stamato, T.D.1    Dipatri, A.2    Giaccia, A.3
  • 60
    • 0029969418 scopus 로고    scopus 로고
    • p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction
    • Sturzbecher, H.W., Donzelmann, B., Henning, W., Knippschild, U. and Buchhop, S. (1996) p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction. EMBO J., 15, 1992-2002.
    • (1996) EMBO J. , vol.15 , pp. 1992-2002
    • Sturzbecher, H.W.1    Donzelmann, B.2    Henning, W.3    Knippschild, U.4    Buchhop, S.5
  • 61
    • 0002571634 scopus 로고
    • Homologous recombination in mitotically dividing mammalian cells
    • Kucherlapati, R. and Smith, G.R. (eds), American Society for Microbiology, Washington DC
    • Subramani, S. and Seaton, B.L. (1988) Homologous recombination in mitotically dividing mammalian cells. In Kucherlapati, R. and Smith, G.R. (eds), Genetic Recombination. American Society for Microbiology, Washington DC, pp. 549-573.
    • (1988) Genetic Recombination , pp. 549-573
    • Subramani, S.1    Seaton, B.L.2
  • 62
    • 0031007450 scopus 로고    scopus 로고
    • Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor
    • Sugawara, H., Kurosaki, M., Takata, M. and Kurosaki, T. (1997) Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor. EMBO J., 16, 3078-3088.
    • (1997) EMBO J. , vol.16 , pp. 3078-3088
    • Sugawara, H.1    Kurosaki, M.2    Takata, M.3    Kurosaki, T.4
  • 63
    • 0028025020 scopus 로고
    • Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
    • Taccioli, G.E. et al. (1994) Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science, 265, 1442-1445.
    • (1994) Science , vol.265 , pp. 1442-1445
    • Taccioli, G.E.1
  • 64
    • 0030018304 scopus 로고    scopus 로고
    • A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ 2
    • Takata, M. and Kurosaki, T. (1996) A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ 2. J. Exp. Med., 184, 31-40.
    • (1996) J. Exp. Med. , vol.184 , pp. 31-40
    • Takata, M.1    Kurosaki, T.2
  • 66
    • 0029949916 scopus 로고    scopus 로고
    • S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes
    • Tashiro, S., Kotomura, N., Shinohara, A., Tanaka, K., Ueda, K. and Kamada, N. (1996) S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes. Oncogene, 12, 2165-2170.
    • (1996) Oncogene , vol.12 , pp. 2165-2170
    • Tashiro, S.1    Kotomura, N.2    Shinohara, A.3    Tanaka, K.4    Ueda, K.5    Kamada, N.6
  • 67
    • 0030849085 scopus 로고    scopus 로고
    • Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
    • Teo, S.-H. and Jackson, S.P. (1997) Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J., 16, 4788-4795.
    • (1997) EMBO J. , vol.16 , pp. 4788-4795
    • Teo, S.-H.1    Jackson, S.P.2
  • 68
    • 0030580940 scopus 로고    scopus 로고
    • Evidence that mammalian cells possess homologous recombinational repair pathways
    • Thompson, L.H. (1996) Evidence that mammalian cells possess homologous recombinational repair pathways. Mutat. Res., 363, 77-88.
    • (1996) Mutat. Res. , vol.363 , pp. 77-88
    • Thompson, L.H.1
  • 70
    • 0029838226 scopus 로고    scopus 로고
    • BTK as a mediator of radiation-induced apoptosis in DT-40 lymphoma B cells
    • Uckun, F.M., Waddick, K.G., Mahajan, S., Jun, X., Takata, M., Bolen, J. and Kurosaki, T. (1996) BTK as a mediator of radiation-induced apoptosis in DT-40 lymphoma B cells. Science, 273, 1096-1100.
    • (1996) Science , vol.273 , pp. 1096-1100
    • Uckun, F.M.1    Waddick, K.G.2    Mahajan, S.3    Jun, X.4    Takata, M.5    Bolen, J.6    Kurosaki, T.7
  • 71
    • 0029117310 scopus 로고
    • What to do at an end: DNA double-strand-break repair
    • Weaver, D.T. (1995) What to do at an end: DNA double-strand-break repair. Trends Genet., 11, 388-392.
    • (1995) Trends Genet. , vol.11 , pp. 388-392
    • Weaver, D.T.1
  • 72
    • 0030811523 scopus 로고    scopus 로고
    • Yeast DNA ligase IV mediates non-homologous DNA end joining
    • Wilson, T.E., Grawunder, U. and Lieber, M.R. (1997) Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature, 388, 495-498.
    • (1997) Nature , vol.388 , pp. 495-498
    • Wilson, T.E.1    Grawunder, U.2    Lieber, M.R.3
  • 74
    • 0029965507 scopus 로고    scopus 로고
    • Cell cycle-dependent expression of the mouse Rad51 gene in proliferating cells
    • Yamamoto, A. et al. (1996) Cell cycle-dependent expression of the mouse Rad51 gene in proliferating cells. Mol. Gen. Genet., 251, 1-12.
    • (1996) Mol. Gen. Genet. , vol.251 , pp. 1-12
    • Yamamoto, A.1
  • 75
    • 0030746109 scopus 로고    scopus 로고
    • Interaction of DNA-dependent protein kinase with DNA and with Ku: Biochemical and atomic-force microscopy studies
    • Yaneva, M., Kowalewski, T. and Lieber, M.R. (1997) Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J., 16, 5098-5112.
    • (1997) EMBO J. , vol.16 , pp. 5098-5112
    • Yaneva, M.1    Kowalewski, T.2    Lieber, M.R.3
  • 76
    • 0028960865 scopus 로고
    • Mammalian mutants defective in the response to ionizing radiation-induced DNA damage
    • Zdzienicka, M.Z. (1995) Mammalian mutants defective in the response to ionizing radiation-induced DNA damage. Mutat. Res., 336, 203-213.
    • (1995) Mutat. Res. , vol.336 , pp. 203-213
    • Zdzienicka, M.Z.1
  • 77
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • Zhu, C., Bogue, M.A., Lim, D.S., Hasty, P. and Roth, D.B. (1996) Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell, 86, 379-389.
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.1    Bogue, M.A.2    Lim, D.S.3    Hasty, P.4    Roth, D.B.5
  • 78
    • 0031444239 scopus 로고    scopus 로고
    • Holliday junctions accumulate in replication mutants via a Reca homolog-independent mechanism
    • Zou, H. and Rothstein, R. (1997) Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism. Cell, 90, 87-96.
    • (1997) Cell , vol.90 , pp. 87-96
    • Zou, H.1    Rothstein, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.