53BP1 inhibits homologous recombination in brca1-deficient cells by blocking resection of DNA breaks

Cell

Volumn 141, Issue 2, 2010, Pages 243-254

  Bunting, Samuel F ^a   Callén, Elsa ^a   Wong, Nancy ^a   Chen, Hua Tang ^a   Polato, Federica ^a   Gunn, Amanda ^d   Bothmer, Anne ^e   Feldhahn, Niklas ^e   Fernandez Capetillo, Oscar ^f   Cao, Liu ^b   Xu, Xiaoling ^c   Deng, Chu Xia ^c   Finkel, Toren ^b   Nussenzweig, Michel ^e   Stark, Jeremy M ^d   Nussenzweig, André ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

^f Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

DNA; Humdisease

Indexed keywords

ATM PROTEIN; BRCA1 PROTEIN; CELL PROTEIN; DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE 4; PROTEIN 53BP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BREAST CANCER; BREAST CARCINOGENESIS; CELL KILLING; CELL MUTANT; CELL PROTECTION; CHROMATID ABERRATION; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME INHIBITION; FEMALE; GENE DELETION; GENE MUTATION; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; INHIBITION KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SIGNAL TRANSDUCTION;

EID: 77950958141     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2010.03.012     Document Type: Article

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