DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy

Frontiers in Oncology

Volumn 3 MAY, Issue , 2013, Pages

  Mladenov, Emil ^a   Magin, Simon ^a   Soni, Aashish ^a   Iliakis, George ^a  

^a UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

Author keywords

Cancer; DNA double strand breaks; Homologous recombination repair; Ionizing radiation; Radiosensitization

Indexed keywords

3' ETHYNYLCYTIDINE; 5 (3 FLUOROPHENYL) N (3 PIPERIDINYL) 3 UREIDO 2 THIOPHENECARBOXAMIDE; ABEXINOSTAT; BCR ABL PROTEIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BRCA1 PROTEIN; BRCA2 PROTEIN; CAFFEINE; CHECKPOINT KINASE 1; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FLUOROURACIL; GIMERACIL; IMATINIB; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PENTOXIFYLLINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P21; PROTEIN P53; PROTEIN TYROSINE KINASE; RAD51 PROTEIN; RAD54 PROTEIN; TANESPIMYCIN; UNCLASSIFIED DRUG; VE 821;

CANCER RADIOTHERAPY; CARCINOGENESIS; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENE EXPRESSION; GENOMIC INSTABILITY; HUMAN; LETHALITY; NONHUMAN; RADIOSENSITIVITY; RADIOSENSITIZATION; RECOMBINATION REPAIR; REVIEW; SIGNAL TRANSDUCTION;

EID: 84879953282     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2013.00113     Document Type: Review

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