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Volumn 26, Issue , 2016, Pages 81-95

Nrf2 signaling and redox homeostasis in the aging heart: A potential target to prevent cardiovascular diseases?

Author keywords

Aging; Cardiovascular system; Nrf2; Oxidative stress

Indexed keywords

ANTIOXIDANT; ARGINASE; ARGINASE II; C REACTIVE PROTEIN; CURCUMIN; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 6; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN; REACTIVE NITROGEN SPECIES; RESVERATROL; S6K1 PROTEIN; SULFORAPHANE; TERT BUTYLHYDROQUINONE; TRANSCRIPTION FACTOR NRF2; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; NFE2L2 PROTEIN, HUMAN;

EID: 84959339029     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2015.12.005     Document Type: Review
Times cited : (69)

References (204)
  • 1
    • 84902546044 scopus 로고    scopus 로고
    • Evaluation of lovastatin effects on expression of anti-apoptotic Nrf2 and PGC-1α genes in neural stem cells treated with hydrogen peroxide
    • Abdanipour A., Tiraihi T., Noori-Zadeh A., Majdi A., Gosaili R. Evaluation of lovastatin effects on expression of anti-apoptotic Nrf2 and PGC-1α genes in neural stem cells treated with hydrogen peroxide. Mol. Neurobiol. 2014, 49:1364-1372. http://dx.doi.org/10.1007/s12035-013-8613-5.
    • (2014) Mol. Neurobiol. , vol.49 , pp. 1364-1372
    • Abdanipour, A.1    Tiraihi, T.2    Noori-Zadeh, A.3    Majdi, A.4    Gosaili, R.5
  • 2
    • 79959523055 scopus 로고    scopus 로고
    • Effects of calorie restriction on cardioprotection and cardiovascular health
    • Ahmet I., Tae H.J., de Cabo R., Lakatta E.G., Talan M.I. Effects of calorie restriction on cardioprotection and cardiovascular health. J. Mol. Cell. Cardiol. 2011, 51:263-271. http://dx.doi.org/10.1016/j.yjmcc.2011.04.015.
    • (2011) J. Mol. Cell. Cardiol. , vol.51 , pp. 263-271
    • Ahmet, I.1    Tae, H.J.2    de Cabo, R.3    Lakatta, E.G.4    Talan, M.I.5
  • 5
    • 84867966112 scopus 로고    scopus 로고
    • Does inflammation determine whether obesity is metabolically healthy or unhealthy? The aging perspective
    • Alam I., Ng T.P., Larbi A. Does inflammation determine whether obesity is metabolically healthy or unhealthy? The aging perspective. Mediat. Inflamm. 2012, 2012:456456. http://dx.doi.org/10.1155/2012/456456.
    • (2012) Mediat. Inflamm. , vol.2012 , pp. 456456
    • Alam, I.1    Ng, T.P.2    Larbi, A.3
  • 8
    • 84883780769 scopus 로고    scopus 로고
    • Proteomic analysis of mature adipocytes from obese patients in relation to aging
    • Alfadda A.A., Benabdelkamel H., Masood A., Moustafa A., Sallam R., Bassas A., Duncan M. Proteomic analysis of mature adipocytes from obese patients in relation to aging. Exp. Gerontol. 2013, 48:1196-1203. http://dx.doi.org/10.1016/j.exger.2013.07.008.
    • (2013) Exp. Gerontol. , vol.48 , pp. 1196-1203
    • Alfadda, A.A.1    Benabdelkamel, H.2    Masood, A.3    Moustafa, A.4    Sallam, R.5    Bassas, A.6    Duncan, M.7
  • 9
    • 15944425804 scopus 로고    scopus 로고
    • Mechanism underlying oxidative stress-mediated lipotoxicity: exposure of J774. 2 Macrophages to triacylglycerols facilitates mitochondrial reactive oxygen species production and cellular necrosis
    • Aronis A., Madar Z., Tirosh O. Mechanism underlying oxidative stress-mediated lipotoxicity: exposure of J774. 2 Macrophages to triacylglycerols facilitates mitochondrial reactive oxygen species production and cellular necrosis. Free Radic. Biol. Med. 2005, 38:1221-1230.
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 1221-1230
    • Aronis, A.1    Madar, Z.2    Tirosh, O.3
  • 10
    • 84922250325 scopus 로고    scopus 로고
    • Involvement of nitric oxide and caveolins in the age-associated functional and structural changes in a heart under osmotic stress
    • Arza P., Netti V., Perosi F., Cernadas G., Ochoa F., Magnani N., Evelson P., Zotta E., Fellet A., Balaszczuk A.M. Involvement of nitric oxide and caveolins in the age-associated functional and structural changes in a heart under osmotic stress. Biomed. Pharmacother. 2015, 69:380-387. http://dx.doi.org/10.1016/j.biopha.2014.12.026.
    • (2015) Biomed. Pharmacother. , vol.69 , pp. 380-387
    • Arza, P.1    Netti, V.2    Perosi, F.3    Cernadas, G.4    Ochoa, F.5    Magnani, N.6    Evelson, P.7    Zotta, E.8    Fellet, A.9    Balaszczuk, A.M.10
  • 11
    • 84892506656 scopus 로고    scopus 로고
    • Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure
    • Asselin C., Ducharme A., Ntimbane T., Ruiz M., Fortier A., Guertin M.C., Lavoie J., Diaz A., Levy E., Tardif J.C., Des-Rosiers C. Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure. Redox Biol. 2013, 2:148-155. http://.dx.doi.org/10.1016/j.redox.2013.12.009.
    • (2013) Redox Biol. , vol.2 , pp. 148-155
    • Asselin, C.1    Ducharme, A.2    Ntimbane, T.3    Ruiz, M.4    Fortier, A.5    Guertin, M.C.6    Lavoie, J.7    Diaz, A.8    Levy, E.9    Tardif, J.C.10    Des-Rosiers, C.11
  • 12
    • 84928751411 scopus 로고    scopus 로고
    • Differences in ischemic damage between young and old hearts-effects of blood cardioplegia
    • Böning A., Rohrbach S., Kohlhepp L., Heep M., Hagmüller S., Niemann B., Mühlfeld C. Differences in ischemic damage between young and old hearts-effects of blood cardioplegia. Exp. Gerontol. 2015, 67:3-8. http://dx.doi.org/10.1016/j.exger.2015.04.012.
    • (2015) Exp. Gerontol. , vol.67 , pp. 3-8
    • Böning, A.1    Rohrbach, S.2    Kohlhepp, L.3    Heep, M.4    Hagmüller, S.5    Niemann, B.6    Mühlfeld, C.7
  • 16
    • 84923233755 scopus 로고    scopus 로고
    • Curcumin binds to the pre-fibrillar aggregates of Cu/Zn superoxide dismutase (SOD1) and alters its amyloidogenic pathway resulting in reduced cytotoxicity
    • Bhatia N.K., Srivastava A., Katyal N., Jain N., Khan M.A., Kundu B., Deep S. Curcumin binds to the pre-fibrillar aggregates of Cu/Zn superoxide dismutase (SOD1) and alters its amyloidogenic pathway resulting in reduced cytotoxicity. Biochim. Biophys. Acta 2015, 1854:426-436. http://dx.doi.org/10.1016/j.bbapap.2015.01.014.
    • (2015) Biochim. Biophys. Acta , vol.1854 , pp. 426-436
    • Bhatia, N.K.1    Srivastava, A.2    Katyal, N.3    Jain, N.4    Khan, M.A.5    Kundu, B.6    Deep, S.7
  • 17
    • 82955248175 scopus 로고    scopus 로고
    • Role of oxidative stress in disease progression in stage B, a pre-cursor of heart failure
    • Bhimaraj A., Tang W.H. Role of oxidative stress in disease progression in stage B, a pre-cursor of heart failure. Heart Fail. Clin. 2012, 8:101-111. arxiv:/http//dx.doi.org/10.1016/j.hfc.2011.08.003.
    • (2012) Heart Fail. Clin. , vol.8 , pp. 101-111
    • Bhimaraj, A.1    Tang, W.H.2
  • 19
    • 84884247290 scopus 로고    scopus 로고
    • Cardiac aging and insulin resistance: could insulin/insulin-like growth factor (IGF) signaling be used as a therapeutic target?
    • Boudina S. Cardiac aging and insulin resistance: could insulin/insulin-like growth factor (IGF) signaling be used as a therapeutic target?. Curr. Pharm. Des. 2013, 19:5684-5694.
    • (2013) Curr. Pharm. Des. , vol.19 , pp. 5684-5694
    • Boudina, S.1
  • 20
    • 84878182000 scopus 로고    scopus 로고
    • Cardiac myocyte-fibroblast interactions and the coronary vasculature
    • Bowers S.L., Baudino T.A. Cardiac myocyte-fibroblast interactions and the coronary vasculature. J. Cardiovasc. Transl. Res. 2012, 5:783-793. http://dx.doi.org/10.1007/s12265-012-9407-2.
    • (2012) J. Cardiovasc. Transl. Res. , vol.5 , pp. 783-793
    • Bowers, S.L.1    Baudino, T.A.2
  • 21
  • 22
    • 84884344861 scopus 로고    scopus 로고
    • Redox activation of Nrf2 & NF-κB: a double end sword?
    • Buelna-Chontal M., Zazueta C. Redox activation of Nrf2 & NF-κB: a double end sword?. Cell Signal. 2013, 25:2548-2557. http://dx.doi.org/10.1016/j.cellsig.2013.08.007.
    • (2013) Cell Signal. , vol.25 , pp. 2548-2557
    • Buelna-Chontal, M.1    Zazueta, C.2
  • 24
    • 38949135755 scopus 로고    scopus 로고
    • Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome
    • Bugger H., Abel E.D. Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome. Clin. Sci. (Lond.) 2008, 114:195-210. http://dx.doi.org/10.1042/cs20070166.
    • (2008) Clin. Sci. (Lond.) , vol.114 , pp. 195-210
    • Bugger, H.1    Abel, E.D.2
  • 30
    • 84947914546 scopus 로고    scopus 로고
    • Activation of endogenous antioxidants as a common therapeutic strategy against cancer, neurodegeneration and cardiovascular diseases: a lesson learnt from DJ-1
    • Chan J.Y., Chan S.H. Activation of endogenous antioxidants as a common therapeutic strategy against cancer, neurodegeneration and cardiovascular diseases: a lesson learnt from DJ-1. Pharmacol. Ther. 2015, 156:69-74. http://dx.doi.org/10.1016/j.pharmthera.2015.09.005.
    • (2015) Pharmacol. Ther. , vol.156 , pp. 69-74
    • Chan, J.Y.1    Chan, S.H.2
  • 31
    • 84861464050 scopus 로고    scopus 로고
    • Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging
    • Chapple S.J., Siow R.C., Mann G.E. Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging. Int. J. Biochem. Cell Biol. 2012, 44:1315-1320. http://dx.doi.org/10.1016/j.biocel.2012.04.021.
    • (2012) Int. J. Biochem. Cell Biol. , vol.44 , pp. 1315-1320
    • Chapple, S.J.1    Siow, R.C.2    Mann, G.E.3
  • 32
    • 84932110967 scopus 로고    scopus 로고
    • The role of Nrf2 in oxidative stress-induced endothelial injuries
    • Chen B., Lu Y., Chen Y., Cheng J. The role of Nrf2 in oxidative stress-induced endothelial injuries. J. Endocrinol. 2015, 225:R83-R99.
    • (2015) J. Endocrinol. , vol.225 , pp. R83-R99
    • Chen, B.1    Lu, Y.2    Chen, Y.3    Cheng, J.4
  • 34
    • 84927915781 scopus 로고    scopus 로고
    • Resveratrol protects against methylglyoxal-induced hyperglycemia and pancreatic damage in vivo
    • Cheng A.S., Cheng Y.H., Lee C.Y., Chung C.Y., Chang W.C. Resveratrol protects against methylglyoxal-induced hyperglycemia and pancreatic damage in vivo. Nutrients 2015, 7:2850-2865. http://dx.doi.org/10.1530/JOE-14-0662.
    • (2015) Nutrients , vol.7 , pp. 2850-2865
    • Cheng, A.S.1    Cheng, Y.H.2    Lee, C.Y.3    Chung, C.Y.4    Chang, W.C.5
  • 36
    • 84920374751 scopus 로고    scopus 로고
    • Curcumin and epigallocatechin gallate inhibit the cancer stem cell phenotype via down-regulation of STAT3-NFκB signaling
    • Chung S.S., Vadgama J.V. Curcumin and epigallocatechin gallate inhibit the cancer stem cell phenotype via down-regulation of STAT3-NFκB signaling. Anticancer Res. 2015, 35:39-46.
    • (2015) Anticancer Res. , vol.35 , pp. 39-46
    • Chung, S.S.1    Vadgama, J.V.2
  • 37
    • 84892470019 scopus 로고    scopus 로고
    • Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway
    • Colín-González A.L., Luna-López A., Königsberg M., Ali S.F., Pedraza-Chaverrí J., Santamaría A. Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway. Neuroscience 2014, 260:130-139. http://dx.doi.org/10.1016/j.neuroscience.2013.12.025.
    • (2014) Neuroscience , vol.260 , pp. 130-139
    • Colín-González, A.L.1    Luna-López, A.2    Königsberg, M.3    Ali, S.F.4    Pedraza-Chaverrí, J.5    Santamaría, A.6
  • 40
    • 21644475628 scopus 로고    scopus 로고
    • Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging
    • Csiszar A., Pacher P., Kaley G., Ungvari Z. Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. Curr. Vasc. Pharmacol. 2005, 3:285-291.
    • (2005) Curr. Vasc. Pharmacol. , vol.3 , pp. 285-291
    • Csiszar, A.1    Pacher, P.2    Kaley, G.3    Ungvari, Z.4
  • 41
    • 84861865625 scopus 로고    scopus 로고
    • Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment
    • Csiszar A., Sosnowska D., Wang M., Lakatta E.G., Sonntag W.E., Ungvari Z. Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment. Gerontol. A Biol. Sci. Med. Sci. 2012, 67:811-820. http://dx.doi.org/10.1093/gerona/glr228.
    • (2012) Gerontol. A Biol. Sci. Med. Sci. , vol.67 , pp. 811-820
    • Csiszar, A.1    Sosnowska, D.2    Wang, M.3    Lakatta, E.G.4    Sonntag, W.E.5    Ungvari, Z.6
  • 42
    • 84942236506 scopus 로고    scopus 로고
    • Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats
    • Csiszar A., Csiszar A., Pinto J.T., Gautam T., Kleusch C., Hoffmann B., Tucsek Z., Toth P., Sonntag W.E., Ungvari Z. Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats. J. Gerontol. A Biol. Sci. Med. Sci. 2015, 70:303-313. http://dx.doi.org/10.1093/gerona/glu029.
    • (2015) J. Gerontol. A Biol. Sci. Med. Sci. , vol.70 , pp. 303-313
    • Csiszar, A.1    Csiszar, A.2    Pinto, J.T.3    Gautam, T.4    Kleusch, C.5    Hoffmann, B.6    Tucsek, Z.7    Toth, P.8    Sonntag, W.E.9    Ungvari, Z.10
  • 44
    • 84928911735 scopus 로고    scopus 로고
    • Long term effect of curcumin in restoration of tumour suppressor p53 and phase-II antioxidant enzymes via activation of nrf2 signalling and modulation of inflammation in prevention of cancer
    • Das L., Vinayak M. Long term effect of curcumin in restoration of tumour suppressor p53 and phase-II antioxidant enzymes via activation of nrf2 signalling and modulation of inflammation in prevention of cancer. PLoS One 2015, 10:e0124000. http://dx.doi.org/10.1371/journal.pone.0124000.
    • (2015) PLoS One , vol.10
    • Das, L.1    Vinayak, M.2
  • 45
    • 77955711544 scopus 로고    scopus 로고
    • Role of autophagy in heart failure associated with aging
    • De Meyer G.R., De Keulenaer G.W., Martinet W. Role of autophagy in heart failure associated with aging. Heart Fail. Rev. 2010, 15:423-430. http://dx.doi.org/10.1007/s10741-010-9166-6.
    • (2010) Heart Fail. Rev. , vol.15 , pp. 423-430
    • De Meyer, G.R.1    De Keulenaer, G.W.2    Martinet, W.3
  • 47
    • 84873298811 scopus 로고    scopus 로고
    • MicroRNAs in age-related diseases
    • Dimmeler S., Nicotera P. MicroRNAs in age-related diseases. EMBO Mol. Med. 2013, 5:180-190. http://dx.doi.org/10.1002/emmm.201201986.
    • (2013) EMBO Mol. Med. , vol.5 , pp. 180-190
    • Dimmeler, S.1    Nicotera, P.2
  • 48
    • 52649084275 scopus 로고    scopus 로고
    • The pathophysiology of cardiovascular disease and diabetes: beyond blood pressure and lipids
    • Dokken B.B. The pathophysiology of cardiovascular disease and diabetes: beyond blood pressure and lipids. Diabetes Spectr. 2008, 21:160-165.
    • (2008) Diabetes Spectr. , vol.21 , pp. 160-165
    • Dokken, B.B.1
  • 49
    • 77649194068 scopus 로고    scopus 로고
    • Prematurely aged children: molecular alterations leading to Hutchinson-Gilford progeria and Werner syndromes
    • Dominguez-Gerpe L., Araujo-Vilar D. Prematurely aged children: molecular alterations leading to Hutchinson-Gilford progeria and Werner syndromes. Curr. Aging Sci. 2008, 1:202-212.
    • (2008) Curr. Aging Sci. , vol.1 , pp. 202-212
    • Dominguez-Gerpe, L.1    Araujo-Vilar, D.2
  • 50
    • 34250216014 scopus 로고    scopus 로고
    • Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB
    • Donato A.J., Eskurza I., Silver A.E., Levy A.S., Pierce G.l., Gates P.E., Seals D.R. Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB. Circ. Res. 2007, 100:1659-1666.
    • (2007) Circ. Res. , vol.100 , pp. 1659-1666
    • Donato, A.J.1    Eskurza, I.2    Silver, A.E.3    Levy, A.S.4    Pierce, G.5    Gates, P.E.6    Seals, D.R.7
  • 51
    • 84934906739 scopus 로고    scopus 로고
    • Cellular and molecular biology of aging endothelial cells
    • Donato A.J., Morgan R.G., Walker A.E., Lesniewski L.A. Cellular and molecular biology of aging endothelial cells. J. Mol. Cell. Cardiol. 2015, 34-36. pii: S0022-2828(15). http://dx.doi.org/10.1016/j.yjmcc.2015.01.021.
    • (2015) J. Mol. Cell. Cardiol. , pp. 34-36
    • Donato, A.J.1    Morgan, R.G.2    Walker, A.E.3    Lesniewski, L.A.4
  • 52
    • 84929657335 scopus 로고    scopus 로고
    • Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized, double-blind, placebo-controlled, crossover trial
    • Dower J.I., Geleijnse J.M., Gijsbers L., Zock P.L., Kromhout D., Hollman P.C. Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized, double-blind, placebo-controlled, crossover trial. Am. J. Clin. Nutr. 2015, 101:914-921. http://.dx.doi.org/10.3945/ajcn.114.098590.
    • (2015) Am. J. Clin. Nutr. , vol.101 , pp. 914-921
    • Dower, J.I.1    Geleijnse, J.M.2    Gijsbers, L.3    Zock, P.L.4    Kromhout, D.5    Hollman, P.C.6
  • 55
    • 84877342029 scopus 로고    scopus 로고
    • Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity
    • Dutta D., Xu J., Kim J.S., Dunn W.A., Leeuwenburgh C. Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity. Autophagy 2013, 9:328-344. http://dx.doi.org/10.4161/auto.22971.
    • (2013) Autophagy , vol.9 , pp. 328-344
    • Dutta, D.1    Xu, J.2    Kim, J.S.3    Dunn, W.A.4    Leeuwenburgh, C.5
  • 56
    • 49949101867 scopus 로고    scopus 로고
    • Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomized controlled trial
    • Ebbing M., Bleie Ø., Ueland P.M., Nordrehaug J.E., Nilsen D.W., Vollset S.E., Refsum H., Pedersen E.K., Nygård Ø. Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomized controlled trial. JAMA 2008, 300:795-804. http://dx.doi.org/10.1001/jama.300.7.795.
    • (2008) JAMA , vol.300 , pp. 795-804
    • Ebbing, M.1    Bleie, Ø.2    Ueland, P.M.3    Nordrehaug, J.E.4    Nilsen, D.W.5    Vollset, S.E.6    Refsum, H.7    Pedersen, E.K.8    Nygård, Ø.9
  • 57
    • 34447299116 scopus 로고    scopus 로고
    • Ischemic preconditioning is lost in aging hypertensive rat heart: independent effects of aging and longstanding hypertension
    • Ebrahim Z., Yellon D.M., Baxter G.F. Ischemic preconditioning is lost in aging hypertensive rat heart: independent effects of aging and longstanding hypertension. Exp. Gerontol. 2007, 42:807-814.
    • (2007) Exp. Gerontol. , vol.42 , pp. 807-814
    • Ebrahim, Z.1    Yellon, D.M.2    Baxter, G.F.3
  • 58
    • 84881187196 scopus 로고    scopus 로고
    • Oxidative stress and vascular inflammation in aging
    • El Assar M., Angulo J., Rodríguez-Mañas L. Oxidative stress and vascular inflammation in aging. Free Radic. Biol. Med. 2013, 65:380-401. http://dx.doi.org/10.1016/j.freeradbiomed.2013.07.003.
    • (2013) Free Radic. Biol. Med. , vol.65 , pp. 380-401
    • El Assar, M.1    Angulo, J.2    Rodríguez-Mañas, L.3
  • 59
    • 84865864438 scopus 로고    scopus 로고
    • Hesperidin-mediated expression of Nrf2 and upregulation of antioxidant status in senescent rat heart
    • Elavarasan J., Velusamy P., Ganesan T., Ramakrishnan S.K., Rajasekaran D., Periandavan K. Hesperidin-mediated expression of Nrf2 and upregulation of antioxidant status in senescent rat heart. J. Pharm. Pharmacol. 2012, 64:1472-1482. http://dx.doi.org/10.1111/j.2042-7158.2012.01512.x.
    • (2012) J. Pharm. Pharmacol. , vol.64 , pp. 1472-1482
    • Elavarasan, J.1    Velusamy, P.2    Ganesan, T.3    Ramakrishnan, S.K.4    Rajasekaran, D.5    Periandavan, K.6
  • 60
    • 84880814584 scopus 로고    scopus 로고
    • Aging might augment reactive oxygen species (ROS) formation and affect reactive nitrogen species (RNS) level after myocardial ischemia/reperfusion in both humans and ratsg might augment reactive oxygen species (ROS) formation and affect reactive nitrogen species (RNS) level after myocardial ischemia/reperfusion in both humans and rats
    • Fan Q., Chen M., Fang X., Lau W.B., Xue L., Zhao L., Zhang H., Liang Y.H., Bai X., Niu H.Y., Ye J., Chen Q., Yang X., Liu M. Aging might augment reactive oxygen species (ROS) formation and affect reactive nitrogen species (RNS) level after myocardial ischemia/reperfusion in both humans and ratsg might augment reactive oxygen species (ROS) formation and affect reactive nitrogen species (RNS) level after myocardial ischemia/reperfusion in both humans and rats. Age (Dordr.) 2013, 35:1017-1026. http://dx.doi.org/10.1007/s11357-012-9421-y.
    • (2013) Age (Dordr.) , vol.35 , pp. 1017-1026
    • Fan, Q.1    Chen, M.2    Fang, X.3    Lau, W.B.4    Xue, L.5    Zhao, L.6    Zhang, H.7    Liang, Y.H.8    Bai, X.9    Niu, H.Y.10    Ye, J.11    Chen, Q.12    Yang, X.13    Liu, M.14
  • 61
    • 85049254849 scopus 로고    scopus 로고
    • Role of glucose and lipids in the cardiovascular disease of patients with diabetes.
    • 2015. In: De Groot, L.J., Beck-Peccoz, P., Chrousos, G., Dungan, K., Grossman, A., Hershman, J.M., Koch, C., McLachlan, R., New, M., Rebar, R., Singer, F., Vinik, A., Weickert, M.O. (Eds), South Dartmouth (MA).
    • Feingold, K., Grunfeld, C., 2000-2015. Role of glucose and lipids in the cardiovascular disease of patients with diabetes. In: De Groot, L.J., Beck-Peccoz, P., Chrousos, G., Dungan, K., Grossman, A., Hershman, J.M., Koch, C., McLachlan, R., New, M., Rebar, R., Singer, F., Vinik, A., Weickert, M.O. (Eds), South Dartmouth (MA).
    • (2000)
    • Feingold, K.1    Grunfeld, C.2
  • 62
    • 0033843973 scopus 로고    scopus 로고
    • Aging reduces the cardioprotective effect of ischemic preconditioning in the rat heart
    • Fenton R.A., Dickson E.W., Meyer T.E., Dobson J.G. Aging reduces the cardioprotective effect of ischemic preconditioning in the rat heart. J. Mol. Cell. Cardiol. 2000, 32:1371-1375.
    • (2000) J. Mol. Cell. Cardiol. , vol.32 , pp. 1371-1375
    • Fenton, R.A.1    Dickson, E.W.2    Meyer, T.E.3    Dobson, J.G.4
  • 63
    • 0347252674 scopus 로고    scopus 로고
    • Endothelial cell oxidative stress and signal transduction
    • Foncea R., Carvajal C., Almarza C., Leighton F. Endothelial cell oxidative stress and signal transduction. Biol. Res. 2000, 33:89-96.
    • (2000) Biol. Res. , vol.33 , pp. 89-96
    • Foncea, R.1    Carvajal, C.2    Almarza, C.3    Leighton, F.4
  • 65
    • 65449125347 scopus 로고    scopus 로고
    • Changes in diastolic dysfunction in diabetes mellitus over time
    • From A.M., Scott C.G., Chen H.H. Changes in diastolic dysfunction in diabetes mellitus over time. Am. J. Cardiol. 2009, 103:1463-1466. http://dx.doi.org/10.1016/j.amjcard.2009.01.358.
    • (2009) Am. J. Cardiol. , vol.103 , pp. 1463-1466
    • From, A.M.1    Scott, C.G.2    Chen, H.H.3
  • 66
    • 0026597674 scopus 로고
    • Purification of senescence marker protein-30 (SMP30) and its androgen-independent decrease with age in the rat liver
    • Fujita T., Uchida K., Maruyama N. Purification of senescence marker protein-30 (SMP30) and its androgen-independent decrease with age in the rat liver. Biochim. Biophys. Acta 1992, 1116:122-128.
    • (1992) Biochim. Biophys. Acta , vol.1116 , pp. 122-128
    • Fujita, T.1    Uchida, K.2    Maruyama, N.3
  • 67
    • 34648816970 scopus 로고    scopus 로고
    • Cellular senescence and chromatin structure
    • Funayama R., Ishiwaka F. Cellular senescence and chromatin structure. Chromosome 2007, 116:431-440.
    • (2007) Chromosome , vol.116 , pp. 431-440
    • Funayama, R.1    Ishiwaka, F.2
  • 68
    • 79551499975 scopus 로고    scopus 로고
    • Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial
    • Galan P., Kesse-Guyot E., Czernichow S., Briancon S., Blacher J., Hercberg S. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial. BMJ 2010, 341:c6273. http://dx.doi.org/10.1136/bmj.c6273.
    • (2010) BMJ , vol.341 , pp. c6273
    • Galan, P.1    Kesse-Guyot, E.2    Czernichow, S.3    Briancon, S.4    Blacher, J.5    Hercberg, S.6
  • 69
    • 14644442283 scopus 로고    scopus 로고
    • Oxygen, oxidative stress, hypoxia, and heart failure
    • Giordano F.J. Oxygen, oxidative stress, hypoxia, and heart failure. J. Clin. Invest. 2005, 115:500-508.
    • (2005) J. Clin. Invest. , vol.115 , pp. 500-508
    • Giordano, F.J.1
  • 71
    • 0038526467 scopus 로고    scopus 로고
    • Cardiomyocyte death and the ageing and failing heart
    • Goldspink D.F., Burniston J.G., Tan L.B. Cardiomyocyte death and the ageing and failing heart. Exp. Physiol. 2003, 88:447-458.
    • (2003) Exp. Physiol. , vol.88 , pp. 447-458
    • Goldspink, D.F.1    Burniston, J.G.2    Tan, L.B.3
  • 72
    • 33846018602 scopus 로고    scopus 로고
    • Cell death by necrosis: towards a molecular definition
    • Goldstein P., Kroemer G. Cell death by necrosis: towards a molecular definition. Trends Biochem. Sci. 2007, 32:37-43.
    • (2007) Trends Biochem. Sci. , vol.32 , pp. 37-43
    • Goldstein, P.1    Kroemer, G.2
  • 73
    • 0036090689 scopus 로고    scopus 로고
    • Activation of the mouse heme oxygenase-1 gene by 15-deoxy-delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2
    • Gong P., Stewart D., Hu B., Li N., Cook J., Nel A., Alam J. Activation of the mouse heme oxygenase-1 gene by 15-deoxy-delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2. Antioxid. Redox Signal. 2002, 4:249-257.
    • (2002) Antioxid. Redox Signal. , vol.4 , pp. 249-257
    • Gong, P.1    Stewart, D.2    Hu, B.3    Li, N.4    Cook, J.5    Nel, A.6    Alam, J.7
  • 75
    • 84906924640 scopus 로고    scopus 로고
    • Understanding the type 2 diabetes mellitus and cardiovascular disease risk paradox
    • Green J.B. Understanding the type 2 diabetes mellitus and cardiovascular disease risk paradox. Postgrad. Med. 2014, 126:190-204. http://dx.doi.org/10.3810/pgm.2014.05.2767.
    • (2014) Postgrad. Med. , vol.126 , pp. 190-204
    • Green, J.B.1
  • 76
    • 84925934623 scopus 로고    scopus 로고
    • Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease
    • Guarner V., Rubio-Ruiz M.E. Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease. Interdiscip. Top. Gerontol. 2015, 40:99-106. http://dx.doi.org/10.1159/000364934.
    • (2015) Interdiscip. Top. Gerontol. , vol.40 , pp. 99-106
    • Guarner, V.1    Rubio-Ruiz, M.E.2
  • 79
    • 77049308856 scopus 로고
    • Aging: a theory based on free radical and radiation chemistry
    • Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 1956, 11:298-300.
    • (1956) J. Gerontol. , vol.11 , pp. 298-300
    • Harman, D.1
  • 81
    • 84873848690 scopus 로고    scopus 로고
    • Myocardial ischemia-reperfusion injury: a neglected therapeutic target
    • Hausenloy D.J., Yellon D.M. Myocardial ischemia-reperfusion injury: a neglected therapeutic target. J. Clin. Invest. 2013, 123:92-100. http://dx.doi.org/10.1172/jci62874.
    • (2013) J. Clin. Invest. , vol.123 , pp. 92-100
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 82
    • 0036890080 scopus 로고    scopus 로고
    • Left ventricular remodeling with age in normal men versus women: novel insights using three-dimensional magnetic resonance imaging
    • Hees P.S., Fleg J.L., Lakatta E.G., Shapiro E.P. Left ventricular remodeling with age in normal men versus women: novel insights using three-dimensional magnetic resonance imaging. Am. J. Cardiol. 2002, 90:1231-1236.
    • (2002) Am. J. Cardiol. , vol.90 , pp. 1231-1236
    • Hees, P.S.1    Fleg, J.L.2    Lakatta, E.G.3    Shapiro, E.P.4
  • 85
    • 84908465812 scopus 로고    scopus 로고
    • Effects of vitamin E, vitamin C and polyphenols on the rate of blood pressure variation: results of two randomised controlled trials
    • Hodgson J.M., Croft K.D., Woodman R.J., Puddey I.B., Bondonno C.P., Wu J.H., Beilin L.J., Lukoshkova E.V., Head G.A., Ward N.C. Effects of vitamin E, vitamin C and polyphenols on the rate of blood pressure variation: results of two randomised controlled trials. Br. J. Nutr. 2014, 112:1551-1561. http://dx.doi.org/10.1017/s0007114514002542.
    • (2014) Br. J. Nutr. , vol.112 , pp. 1551-1561
    • Hodgson, J.M.1    Croft, K.D.2    Woodman, R.J.3    Puddey, I.B.4    Bondonno, C.P.5    Wu, J.H.6    Beilin, L.J.7    Lukoshkova, E.V.8    Head, G.A.9    Ward, N.C.10
  • 86
    • 84939181087 scopus 로고    scopus 로고
    • Comparison of coenzyme Q10 versus placebo in chronic heart failure
    • Hosseini V.N. Comparison of coenzyme Q10 versus placebo in chronic heart failure. Res. J. Biol. Sci. 2008, 3:884-887. ISSN. 1815-8846.
    • (2008) Res. J. Biol. Sci. , vol.3 , pp. 884-887
    • Hosseini, V.N.1
  • 88
    • 84983150554 scopus 로고    scopus 로고
    • The complexity of the Nrf2 pathway: beyond the antioxidant response
    • pii:S0955-2863
    • Huang Y., Li W., Su Z.Y., Kong A.T. The complexity of the Nrf2 pathway: beyond the antioxidant response. J. Nutr. Biochem. 2015, 179-185. pii:S0955-2863. http://dx.doi.org/10.1016/j.jnutbio.2015.08.001.
    • (2015) J. Nutr. Biochem. , pp. 179-185
    • Huang, Y.1    Li, W.2    Su, Z.Y.3    Kong, A.T.4
  • 89
    • 84887562469 scopus 로고    scopus 로고
    • Update on heart failure with preserved ejection fraction
    • Hummel S.L., Kitzman D.W. Update on heart failure with preserved ejection fraction. Curr. Cardiovasc. Risk Rep. 2013, 7:495-502.
    • (2013) Curr. Cardiovasc. Risk Rep. , vol.7 , pp. 495-502
    • Hummel, S.L.1    Kitzman, D.W.2
  • 90
    • 67650828068 scopus 로고    scopus 로고
    • A comparative analysis of the cell biology of senescence and aging
    • Hwang E., Yoon G., Kang H. A comparative analysis of the cell biology of senescence and aging. Cell. Mol. Life Sci. 2009, 66:2503-2524. http://dx.doi.org/10.1007/s00018-009-0034-2.
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 2503-2524
    • Hwang, E.1    Yoon, G.2    Kang, H.3
  • 91
    • 84875209872 scopus 로고    scopus 로고
    • Renal denervation abolishes the age-dependent increase in blood pressure in female intrauterine growth-restricted rats at 12 months of age
    • Intapad S., Tull F.L., Brown A.D., Dasinger J.H., Ojeda N.B., Fahling J.M., Alexander B.T. Renal denervation abolishes the age-dependent increase in blood pressure in female intrauterine growth-restricted rats at 12 months of age. Hypertension 2013, 61:828-834. http://dx.doi.org/10.1161/hypertensionaha.111.00645.
    • (2013) Hypertension , vol.61 , pp. 828-834
    • Intapad, S.1    Tull, F.L.2    Brown, A.D.3    Dasinger, J.H.4    Ojeda, N.B.5    Fahling, J.M.6    Alexander, B.T.7
  • 92
    • 0035896220 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice
    • Ishikawa K., Sugawara D., Wang Xp., Suzuki K., Itabe H., Maruyama Y., Lusis A.J. Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice. Circ. Res. 2001, 88:506-512.
    • (2001) Circ. Res. , vol.88 , pp. 506-512
    • Ishikawa, K.1    Sugawara, D.2    Wang, X.3    Suzuki, K.4    Itabe, H.5    Maruyama, Y.6    Lusis, A.J.7
  • 94
    • 4143141119 scopus 로고    scopus 로고
    • Transport of resveratrol, a cancer chemopreventive agent, to cellular targets: plasmatic protein binding and cell uptake
    • Jannin B., Menzel M., Berlot J.P., Delmas D., Lancon A., Latruffe N. Transport of resveratrol, a cancer chemopreventive agent, to cellular targets: plasmatic protein binding and cell uptake. Biochem. Pharmacol. 2004, 68:1113-1118.
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 1113-1118
    • Jannin, B.1    Menzel, M.2    Berlot, J.P.3    Delmas, D.4    Lancon, A.5    Latruffe, N.6
  • 95
    • 30344486998 scopus 로고    scopus 로고
    • Oxidative stress and diabetic cardiovascular complications
    • Jay D., Hitomi H., Griendling K.K. Oxidative stress and diabetic cardiovascular complications. Free Radic. Biol. Med. 2006, 40:183-192.
    • (2006) Free Radic. Biol. Med. , vol.40 , pp. 183-192
    • Jay, D.1    Hitomi, H.2    Griendling, K.K.3
  • 97
    • 84906220144 scopus 로고    scopus 로고
    • Radicales Libres y Estrés Oxidativo: Aplicaciones Médicas.
    • In: Moderno, (), México.
    • Königsberg, M., 2008. Radicales Libres y Estrés Oxidativo: Aplicaciones Médicas. In: Moderno, (), México.
    • (2008)
    • Königsberg, M.1
  • 101
    • 0026648469 scopus 로고
    • Comparative life spans of species: why do species have the life spans they do?
    • Kirkwood T.B. Comparative life spans of species: why do species have the life spans they do?. Am. J. Clin. Nutr. 1992, 55:1191S-1195S.
    • (1992) Am. J. Clin. Nutr. , vol.55 , pp. 1191S-1195S
    • Kirkwood, T.B.1
  • 103
    • 84901425505 scopus 로고    scopus 로고
    • Aging, exercise, and extracellular matrix in the heart
    • Kwak H.B. Aging, exercise, and extracellular matrix in the heart. J. Exerc. Rehabil. 2013, 9:338-347. http://dx.doi.org/10.12965/jer.130049.
    • (2013) J. Exerc. Rehabil. , vol.9 , pp. 338-347
    • Kwak, H.B.1
  • 105
    • 0037469206 scopus 로고    scopus 로고
    • Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. Part III: cellular and molecular clues to heart and arterial aging
    • Lakatta E.G. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. Part III: cellular and molecular clues to heart and arterial aging. Circulation 2003, 107:490-497.
    • (2003) Circulation , vol.107 , pp. 490-497
    • Lakatta, E.G.1
  • 106
    • 21444438990 scopus 로고    scopus 로고
    • Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's health study: a randomized controlled trial
    • Lee I.M., Cook N.R., Gaziano J.M., Gordon D., Ridker P.M., Manson J.E., Hennekens C.H., Buring J.E. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's health study: a randomized controlled trial. JAMA 2005, 294:56-65.
    • (2005) JAMA , vol.294 , pp. 56-65
    • Lee, I.M.1    Cook, N.R.2    Gaziano, J.M.3    Gordon, D.4    Ridker, P.M.5    Manson, J.E.6    Hennekens, C.H.7    Buring, J.E.8
  • 107
    • 72049129981 scopus 로고    scopus 로고
    • Senescence of cultured porcine coronary arterial endothelial cells is associated with accelerated oxidative stress and activation of NFκB
    • Lee M.Y., Wang Y., Vanhoutte P.M. Senescence of cultured porcine coronary arterial endothelial cells is associated with accelerated oxidative stress and activation of NFκB. J. Vasc. Res. 2010, 47:287-298. http://dx.doi.org/10.1159/000265563.
    • (2010) J. Vasc. Res. , vol.47 , pp. 287-298
    • Lee, M.Y.1    Wang, Y.2    Vanhoutte, P.M.3
  • 108
    • 32444444967 scopus 로고    scopus 로고
    • Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury
    • Li D., Qu Y., Tao L., Liu H., Hu A., Gao F., Sharifi-Azad S., Grunwald Z., Ma X.L., Sun J.Z. Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury. J. Surg. Res. 2006, 131:64-72.
    • (2006) J. Surg. Res. , vol.131 , pp. 64-72
    • Li, D.1    Qu, Y.2    Tao, L.3    Liu, H.4    Hu, A.5    Gao, F.6    Sharifi-Azad, S.7    Grunwald, Z.8    Ma, X.L.9    Sun, J.Z.10
  • 110
    • 79955418633 scopus 로고    scopus 로고
    • Up-regulation of p27(kip1) contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy
    • Li J., Zhang C., Xing Y., Janicki J.S., Yamamoto M., Wang X.L., Tang D.Q., Cui T. Up-regulation of p27(kip1) contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy. Cardiovasc. Res. 2011, 90:315-324. http://dx.doi.org/10.1093/cvr/cvr010.
    • (2011) Cardiovasc. Res. , vol.90 , pp. 315-324
    • Li, J.1    Zhang, C.2    Xing, Y.3    Janicki, J.S.4    Yamamoto, M.5    Wang, X.L.6    Tang, D.Q.7    Cui, T.8
  • 111
    • 84897423410 scopus 로고    scopus 로고
    • Activating transcription factor 3 protects against pressure-overload heart failure via the autophagy molecule beclin-1 pathway
    • Lin H., Li H.F., Chen H.H., Lai P.F., Juan S.H., Chen J.J., Cheng C.F. Activating transcription factor 3 protects against pressure-overload heart failure via the autophagy molecule beclin-1 pathway. Mol. Pharmacol. 2014, 85:682-691. http://dx.doi.org/10.1124/mol.113.090092.
    • (2014) Mol. Pharmacol. , vol.85 , pp. 682-691
    • Lin, H.1    Li, H.F.2    Chen, H.H.3    Lai, P.F.4    Juan, S.H.5    Chen, J.J.6    Cheng, C.F.7
  • 112
    • 84947227218 scopus 로고    scopus 로고
    • Downregulation of nuclear factor erythroid 2-related factor and associated antioxidant genes contributes to redox-sensitive vascular dysfunction in hypertension
    • Lopes R.A., Neves K.B., Tostes R.C., Montezano A.C., Touyz R.M. Downregulation of nuclear factor erythroid 2-related factor and associated antioxidant genes contributes to redox-sensitive vascular dysfunction in hypertension. Hypertension 2015, 66:1240-1250. http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06163.
    • (2015) Hypertension , vol.66 , pp. 1240-1250
    • Lopes, R.A.1    Neves, K.B.2    Tostes, R.C.3    Montezano, A.C.4    Touyz, R.M.5
  • 113
    • 0029091366 scopus 로고
    • Nitric oxide and its role in the cardiovascular system
    • Loscalzo J., Welch G. Nitric oxide and its role in the cardiovascular system. Prog. Cardiovasc. Dis. 1995, 38:87-104.
    • (1995) Prog. Cardiovasc. Dis. , vol.38 , pp. 87-104
    • Loscalzo, J.1    Welch, G.2
  • 114
    • 0031930041 scopus 로고    scopus 로고
    • Cardiac reperfusion injury: aging, lipid peroxidation, and mitochondrial dysfunction
    • Lucas D.T., Szweda L.I. Cardiac reperfusion injury: aging, lipid peroxidation, and mitochondrial dysfunction. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:510-514.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 510-514
    • Lucas, D.T.1    Szweda, L.I.2
  • 116
    • 37549051753 scopus 로고    scopus 로고
    • Regulation of NADPH oxidase subunit p22(phox) by NF-kB in human aortic smooth muscle cells
    • Manea A., Manea S.A., Gafencu A.V., Raicu M. Regulation of NADPH oxidase subunit p22(phox) by NF-kB in human aortic smooth muscle cells. Arch. Physiol. Biochem. 2007, 113:163-172.
    • (2007) Arch. Physiol. Biochem. , vol.113 , pp. 163-172
    • Manea, A.1    Manea, S.A.2    Gafencu, A.V.3    Raicu, M.4
  • 117
    • 33746543323 scopus 로고    scopus 로고
    • Cellular and molecular events in ischemic preconditioning: potential therapeutic applications in cardioprotection
    • Marín-García J. Cellular and molecular events in ischemic preconditioning: potential therapeutic applications in cardioprotection. Future Cardiol. 2005, 1:111-122. http://dx.doi.org/10.1517/14796678.1.1.111.
    • (2005) Future Cardiol. , vol.1 , pp. 111-122
    • Marín-García, J.1
  • 122
    • 84866168708 scopus 로고    scopus 로고
    • Sulforaphane prevention of diabetes-induced aortic damage was associated with the up-regulation of Nrf2 and its down-stream antioxidants
    • Miao X., Bai Y., Sun W., Cui W., Xin Y., Wang Y., Tan Y., Miao L., Fu Y., Su G., Cai L. Sulforaphane prevention of diabetes-induced aortic damage was associated with the up-regulation of Nrf2 and its down-stream antioxidants. Nutr. Metab. (Lond.) 2012, 9:84. http://dx.doi.org/10.1186/1743-7075-9-84.
    • (2012) Nutr. Metab. (Lond.) , vol.9 , pp. 84
    • Miao, X.1    Bai, Y.2    Sun, W.3    Cui, W.4    Xin, Y.5    Wang, Y.6    Tan, Y.7    Miao, L.8    Fu, Y.9    Su, G.10    Cai, L.11
  • 128
    • 84923212398 scopus 로고    scopus 로고
    • Q-SYMBIO study investigators. the effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial
    • Mortensen S.A., Rosenfeldt F., Kumar A., Dolliner P., Filipiak K.J., Pella D., Alehagen U., Steurer G., Littarru G.P. Q-SYMBIO study investigators. the effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC Heart Fail. 2014, 2:641-649. http://dx.doi.org/10.1016/j.jchf.2014.06.008.
    • (2014) JACC Heart Fail. , vol.2 , pp. 641-649
    • Mortensen, S.A.1    Rosenfeldt, F.2    Kumar, A.3    Dolliner, P.4    Filipiak, K.J.5    Pella, D.6    Alehagen, U.7    Steurer, G.8    Littarru, G.P.9
  • 129
    • 84898790918 scopus 로고    scopus 로고
    • Mechanisms of load dependency of myocardial ischemia reperfusion injury
    • Mozaffari M.S., Liu J.Y., Abebe W., Baban B. Mechanisms of load dependency of myocardial ischemia reperfusion injury. Am. J. Cardiovasc. Dis. 2013, 3:180-196.
    • (2013) Am. J. Cardiovasc. Dis. , vol.3 , pp. 180-196
    • Mozaffari, M.S.1    Liu, J.Y.2    Abebe, W.3    Baban, B.4
  • 130
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium
    • Murry C.E., Jennings R.B., Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986, 74:1124-1136.
    • (1986) Circulation , vol.74 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 131
    • 84942897142 scopus 로고    scopus 로고
    • Resveratrol preconditioning protects against cerebral ischemic injury via nuclear erythroid 2-related factor 2
    • Narayanan S.V., Dave K.R., Saul I., Perez-Pinzon M.A. Resveratrol preconditioning protects against cerebral ischemic injury via nuclear erythroid 2-related factor 2. Stroke 2015, 46:1626-1632. http://dx.doi.org/10.1161/STROKEAHA.115.008921.
    • (2015) Stroke , vol.46 , pp. 1626-1632
    • Narayanan, S.V.1    Dave, K.R.2    Saul, I.3    Perez-Pinzon, M.A.4
  • 132
    • 84940866591 scopus 로고    scopus 로고
    • Calpain system and its involvement in myocardial ischemia and reperfusion injury
    • Neuhof C., Neuhof H. Calpain system and its involvement in myocardial ischemia and reperfusion injury. World J. Cardiol. 2014, 6:638-652. http://dx.doi.org/10.4330/wjc.v6.i7.638.
    • (2014) World J. Cardiol. , vol.6 , pp. 638-652
    • Neuhof, C.1    Neuhof, H.2
  • 133
    • 79251478801 scopus 로고    scopus 로고
    • Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria
    • Niemann B., Chen Y., Teschner M., Li L., Silber R.E., Rohrbach S. Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria. J. Am. Coll. Cardiol. 2011, 57:577-585. http://dx.doi.org/10.1016/j.jacc.2010.09.040.
    • (2011) J. Am. Coll. Cardiol. , vol.57 , pp. 577-585
    • Niemann, B.1    Chen, Y.2    Teschner, M.3    Li, L.4    Silber, R.E.5    Rohrbach, S.6
  • 135
    • 84859882975 scopus 로고    scopus 로고
    • The intersection between aging and cardiovascular disease
    • North B.J., Sinclair D.A. The intersection between aging and cardiovascular disease. Circ. Res. 2012, 110:1097-1108. http://dx.doi.org/10.1161/circresaha.111.246876.
    • (2012) Circ. Res. , vol.110 , pp. 1097-1108
    • North, B.J.1    Sinclair, D.A.2
  • 137
    • 84890798751 scopus 로고    scopus 로고
    • Cell death in the myocardium: my heart won't go on
    • Orongo A.M., Gustafsson A.B. Cell death in the myocardium: my heart won't go on. IUBMB Life 2013, 65:651-656. http://dx.doi.org/10.1002/iub.1180.
    • (2013) IUBMB Life , vol.65 , pp. 651-656
    • Orongo, A.M.1    Gustafsson, A.B.2
  • 140
    • 84879748718 scopus 로고    scopus 로고
    • A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation
    • Paulus W.J., Tschope C. A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J. Am. Coll. Cardiol. 2013, 62:263-271. http://dx.doi.org/10.1016/j.jacc.2013.02.092.
    • (2013) J. Am. Coll. Cardiol. , vol.62 , pp. 263-271
    • Paulus, W.J.1    Tschope, C.2
  • 142
    • 84902687763 scopus 로고    scopus 로고
    • SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts
    • Porter G.A., Urciuoli W.R., Brookes P.S., Nadtochiy S.M. SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts. Am. J. Physiol. Heart Circ. Physiol. 2014, 306:H1602-H1609. http://dx.doi.org/10.1152/ajpheart.00027.2014.
    • (2014) Am. J. Physiol. Heart Circ. Physiol. , vol.306 , pp. H1602-H1609
    • Porter, G.A.1    Urciuoli, W.R.2    Brookes, P.S.3    Nadtochiy, S.M.4
  • 143
    • 84916940622 scopus 로고    scopus 로고
    • Aging and injury: alterations in cellular energetics and organ function
    • Poulose N., Raju R. Aging and injury: alterations in cellular energetics and organ function. Aging Dis. 2014, 5:101-108. http://dx.doi.org/10.14336/AD.2014.0500101.
    • (2014) Aging Dis. , vol.5 , pp. 101-108
    • Poulose, N.1    Raju, R.2
  • 144
    • 84890741956 scopus 로고    scopus 로고
    • Dietary curcumin ameliorates aging-related cerebrovascular dysfunction through the AMPK/uncoupling protein 2 pathway
    • Pu Y., Zhang H., Wang P., Zhao Y., Li Q., Wei X., Cui Y., Sun J., Shang Q., Liu D., Zhu Z. Dietary curcumin ameliorates aging-related cerebrovascular dysfunction through the AMPK/uncoupling protein 2 pathway. Cell. Physiol. Biochem. 2013, 32:1167-1177. http://dx.doi.org/10.1159/000354516.
    • (2013) Cell. Physiol. Biochem. , vol.32 , pp. 1167-1177
    • Pu, Y.1    Zhang, H.2    Wang, P.3    Zhao, Y.4    Li, Q.5    Wei, X.6    Cui, Y.7    Sun, J.8    Shang, Q.9    Liu, D.10    Zhu, Z.11
  • 145
    • 84924240679 scopus 로고    scopus 로고
    • Effects of prediabetes mellitus alone or plus hypertension on subsequent occurrence of cardiovascular disease and diabetes mellitus: longitudinal study
    • Qiu M., Shen W., Song X., Ju L., Tong W., Wang H., Zheng S., Jin Y., Wu Y., Wang W., Tian J. Effects of prediabetes mellitus alone or plus hypertension on subsequent occurrence of cardiovascular disease and diabetes mellitus: longitudinal study. Hypertension 2015, 65:525-530. http://dx.doi.org/10.1161/hypertensionaha.114.04632.
    • (2015) Hypertension , vol.65 , pp. 525-530
    • Qiu, M.1    Shen, W.2    Song, X.3    Ju, L.4    Tong, W.5    Wang, H.6    Zheng, S.7    Jin, Y.8    Wu, Y.9    Wang, W.10    Tian, J.11
  • 147
    • 79951918162 scopus 로고    scopus 로고
    • Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice
    • Rajasekaran N.S., Varadharaj S., Khanderao G.D., Davidson C.J., Kannan S., Firpo M.A., Zweier J.L., Benjamin I.J. Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice. Antioxid. Redox Signal. 2011, 14:957-971. http://dx.doi.org/10.1089/ars.2010.3587.
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 957-971
    • Rajasekaran, N.S.1    Varadharaj, S.2    Khanderao, G.D.3    Davidson, C.J.4    Kannan, S.5    Firpo, M.A.6    Zweier, J.L.7    Benjamin, I.J.8
  • 149
    • 84894227008 scopus 로고    scopus 로고
    • Genetics of oxidative stress in obesity
    • Rupérez A.I., Gil A., Aguilera C.M. Genetics of oxidative stress in obesity. Int. J. Mol. Sci. 2014, 15:3118-3144. http://dx.doi.org/10.3390/ijms15023118.
    • (2014) Int. J. Mol. Sci. , vol.15 , pp. 3118-3144
    • Rupérez, A.I.1    Gil, A.2    Aguilera, C.M.3
  • 151
    • 4243550127 scopus 로고    scopus 로고
    • Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance
    • Ryter S.W., Otterbein L.E., Morse D., Choi A.M. Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance. Mol. Cell Biochem. 2002, 234-235:249-263.
    • (2002) Mol. Cell Biochem. , pp. 249-263
    • Ryter, S.W.1    Otterbein, L.E.2    Morse, D.3    Choi, A.M.4
  • 152
    • 84868275732 scopus 로고    scopus 로고
    • Role of HO/CO in the control of peripheral circulation in humans
    • Sacerdoti D., Mania D., Pesce P., Gaiani S., Gatta A., Bolognesi M. Role of HO/CO in the control of peripheral circulation in humans. Int. J. Hypertens. 2012, 2012:236180. http://dx.doi.org/10.1155/2012/236180.
    • (2012) Int. J. Hypertens. , vol.2012 , pp. 236180
    • Sacerdoti, D.1    Mania, D.2    Pesce, P.3    Gaiani, S.4    Gatta, A.5    Bolognesi, M.6
  • 153
    • 0030969371 scopus 로고    scopus 로고
    • The cellular and molecular response of cardiac myocytes to mechanical stress
    • Sadoshima J., Izumo S. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu. Rev. Physiol. 1997, 59:551-571.
    • (1997) Annu. Rev. Physiol. , vol.59 , pp. 551-571
    • Sadoshima, J.1    Izumo, S.2
  • 154
    • 77957756428 scopus 로고    scopus 로고
    • Dysfunctional Nrf2-Keap1 redox signaling in skeletal muscle of the sedentary old
    • Safdar A., deBeer J., Tarnopolsky M.A. Dysfunctional Nrf2-Keap1 redox signaling in skeletal muscle of the sedentary old. Free Radic. Biol. Med. 2010, 49:1487-1493. http://dx.doi.org/10.1016/j.freeradbiomed.2010.08.010.
    • (2010) Free Radic. Biol. Med. , vol.49 , pp. 1487-1493
    • Safdar, A.1    deBeer, J.2    Tarnopolsky, M.A.3
  • 155
    • 84884799597 scopus 로고    scopus 로고
    • The senescence-accelerated mouse-prone 8 is not a suitable model for the investigation of cardiac inflammation and oxidative stress and their modulation by dietary phytochemicals
    • Schiborr C., Schwamm D., Kocher A., Rimbach G., Eckert G.P., Frank J. The senescence-accelerated mouse-prone 8 is not a suitable model for the investigation of cardiac inflammation and oxidative stress and their modulation by dietary phytochemicals. Pharmacol. Res. 2013, 74:113-120. http://dx.doi.org/10.1016/j.phrs.2013.06.004.
    • (2013) Pharmacol. Res. , vol.74 , pp. 113-120
    • Schiborr, C.1    Schwamm, D.2    Kocher, A.3    Rimbach, G.4    Eckert, G.P.5    Frank, J.6
  • 156
    • 77649232263 scopus 로고    scopus 로고
    • Energetic myocardial metabolism and oxidative stress: let's make them our friends in the fight against heart failure
    • Scolletta S., Biagioli B. Energetic myocardial metabolism and oxidative stress: let's make them our friends in the fight against heart failure. Biomed. Pharmacother. 2010, 64:203-207. http://dx.doi.org/10.1016/j.biopha.2009.10.002.
    • (2010) Biomed. Pharmacother. , vol.64 , pp. 203-207
    • Scolletta, S.1    Biagioli, B.2
  • 157
    • 84876522971 scopus 로고    scopus 로고
    • Effects of caloric restriction on cardiac oxidative stress and mitochondrial bioenergetics: potential role of cardiac sirtuins
    • Shinmura K. Effects of caloric restriction on cardiac oxidative stress and mitochondrial bioenergetics: potential role of cardiac sirtuins. Oxid. Med. Cell. Longev. 2013, 2013:528935. http://dx.doi.org/10.1155/2013/528935.
    • (2013) Oxid. Med. Cell. Longev. , vol.2013 , pp. 528935
    • Shinmura, K.1
  • 158
    • 84869086654 scopus 로고    scopus 로고
    • Aging as a substrate of heart failure
    • Shioi T., Inuzuka Y. Aging as a substrate of heart failure. J. Cardiol. 2012, 60:423-428. http://dx.doi.org/10.1016/j.jjcc.2012.07.015.
    • (2012) J. Cardiol. , vol.60 , pp. 423-428
    • Shioi, T.1    Inuzuka, Y.2
  • 159
    • 0028328777 scopus 로고
    • Determination of left ventricular mass by echocardiography in a normal population: effect of age and sex in addition to body size
    • Shub C., Klein A.L., Zachariah P.K., Bailey K.R., Tajik A.J. Determination of left ventricular mass by echocardiography in a normal population: effect of age and sex in addition to body size. Mayo Clin. Proc. 1994, 69:205-211.
    • (1994) Mayo Clin. Proc. , vol.69 , pp. 205-211
    • Shub, C.1    Klein, A.L.2    Zachariah, P.K.3    Bailey, K.R.4    Tajik, A.J.5
  • 160
    • 84906317267 scopus 로고    scopus 로고
    • Advances in the understanding of the pathophysiology and management of aortic stenosis: role of novel imaging techniques
    • Singh A., Steadman C.D., McCann G.P. Advances in the understanding of the pathophysiology and management of aortic stenosis: role of novel imaging techniques. Can. J. Cardiol. 2014, 30:994-1003. http://dx.doi.org/10.1016/j.cjca.2014.03.008.
    • (2014) Can. J. Cardiol. , vol.30 , pp. 994-1003
    • Singh, A.1    Steadman, C.D.2    McCann, G.P.3
  • 161
    • 84924227907 scopus 로고    scopus 로고
    • Nicotinamide adenine dinucleotide phosphate oxidase-4-dependent upregulation of nuclear factor erythroid-derived 2-like 2 protects the heart during chronic pressure overload
    • Smyrnias I., Zhang X., Zhang M., Murray T.V., Brandes R.P., Schröder K., Brewer A.C., Shah A.M. Nicotinamide adenine dinucleotide phosphate oxidase-4-dependent upregulation of nuclear factor erythroid-derived 2-like 2 protects the heart during chronic pressure overload. Hypertension 2015, 65:547-553. http://dx.doi.org/10.1161/hypertensionaha.114.04208.
    • (2015) Hypertension , vol.65 , pp. 547-553
    • Smyrnias, I.1    Zhang, X.2    Zhang, M.3    Murray, T.V.4    Brandes, R.P.5    Schröder, K.6    Brewer, A.C.7    Shah, A.M.8
  • 162
    • 78751512092 scopus 로고    scopus 로고
    • Peroxynitrite-driven mechanisms in diabetes and insulin resistance-the latest advances
    • Stadler K. Peroxynitrite-driven mechanisms in diabetes and insulin resistance-the latest advances. Curr. Med. Chem. 2011, 18:280-290.
    • (2011) Curr. Med. Chem. , vol.18 , pp. 280-290
    • Stadler, K.1
  • 163
    • 82955249843 scopus 로고    scopus 로고
    • Aging-associated cardiovascular changes and their relationship to heart failure
    • Strait J.B., Lakatta E.G. Aging-associated cardiovascular changes and their relationship to heart failure. Heart Fail. Clin. 2012, 8:143-164. http://dx.doi.org/10.1016/j.hfc.2011.08.011.
    • (2012) Heart Fail. Clin. , vol.8 , pp. 143-164
    • Strait, J.B.1    Lakatta, E.G.2
  • 164
    • 1542723493 scopus 로고    scopus 로고
    • Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
    • Suh J.H., Shenvi S.V., Dixon B.M., Liu H., Jaiswal A.K., Liu R.M., Hagen T.M. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:3381-3386.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 3381-3386
    • Suh, J.H.1    Shenvi, S.V.2    Dixon, B.M.3    Liu, H.4    Jaiswal, A.K.5    Liu, R.M.6    Hagen, T.M.7
  • 165
    • 84921538872 scopus 로고    scopus 로고
    • Aging, arterial stiffness, and hypertension
    • Sun Z. Aging, arterial stiffness, and hypertension. Hypertension 2015, 65:252-256. http://dx.doi.org/10.1161/hypertensionaha.114.03617.
    • (2015) Hypertension , vol.65 , pp. 252-256
    • Sun, Z.1
  • 166
    • 84897498823 scopus 로고    scopus 로고
    • Cardiac electrophysiological alterations in heart/muscle-specific manganese-superoxide dismutase-deficient mice: prevention by a dietary antioxidant polyphenol
    • Sunagawa T., Shimizu T., Matsumoto A., Tagashira M., Kanda T., Shirasawa T., Nakaya H. Cardiac electrophysiological alterations in heart/muscle-specific manganese-superoxide dismutase-deficient mice: prevention by a dietary antioxidant polyphenol. Biomed. Res. Int. 2014, 2014:704291. http://dx.doi.org/10.1155/2014/704291.
    • (2014) Biomed. Res. Int. , vol.2014 , pp. 704291
    • Sunagawa, T.1    Shimizu, T.2    Matsumoto, A.3    Tagashira, M.4    Kanda, T.5    Shirasawa, T.6    Nakaya, H.7
  • 167
    • 84862677856 scopus 로고    scopus 로고
    • Age-related cardiovascular disease and the beneficial effects of calorie restriction
    • Sung M.M., Dyck J.R. Age-related cardiovascular disease and the beneficial effects of calorie restriction. Heart Fail. Rev. 2012, 17:707-719. http://dx.doi.org/10.1007/s10741-011-9293-8.
    • (2012) Heart Fail. Rev. , vol.17 , pp. 707-719
    • Sung, M.M.1    Dyck, J.R.2
  • 168
    • 0029018755 scopus 로고
    • Basophilic degeneration of the myocardium: histological, immunohistochemical and immuno-electronmicroscopic studies
    • Tamura S., Takahashi M., Kawamura S., Ishihara T. Basophilic degeneration of the myocardium: histological, immunohistochemical and immuno-electronmicroscopic studies. Histopathology 1995, 26:501-508.
    • (1995) Histopathology , vol.26 , pp. 501-508
    • Tamura, S.1    Takahashi, M.2    Kawamura, S.3    Ishihara, T.4
  • 169
    • 77950901103 scopus 로고    scopus 로고
    • Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure
    • Tanno M., Kuno A., Yano T., Miura T., Hisahara S., Ishikawa S., Shimamoto K., Horio Y. Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure. J. Biol. Chem. 2010, 285:8375-8382. http://dx.doi.org/10.1074/jbc.m109.090266.
    • (2010) J. Biol. Chem. , vol.285 , pp. 8375-8382
    • Tanno, M.1    Kuno, A.2    Yano, T.3    Miura, T.4    Hisahara, S.5    Ishikawa, S.6    Shimamoto, K.7    Horio, Y.8
  • 173
    • 84922271976 scopus 로고    scopus 로고
    • Dietary broccoli mildly improves neuroinflammation in aged mice but does not reduce lipopolysaccharide-induced sickness behavior
    • Townsend B.E., Chen Y.J., Jeffery E.H., Johnson R.W. Dietary broccoli mildly improves neuroinflammation in aged mice but does not reduce lipopolysaccharide-induced sickness behavior. Nutr. Res. 2014, 34:990-999. http://dx.doi.org/10.1016/j.nutres.2014.10.001.
    • (2014) Nutr. Res. , vol.34 , pp. 990-999
    • Townsend, B.E.1    Chen, Y.J.2    Jeffery, E.H.3    Johnson, R.W.4
  • 174
    • 78049280211 scopus 로고    scopus 로고
    • Pathophysiological relevance of NO signaling in the cardiovascular system: novel insight from mice lacking all NO synthases
    • Tsutsui M., Shimokawa H., Otsuji Y., Yanagihara N. Pathophysiological relevance of NO signaling in the cardiovascular system: novel insight from mice lacking all NO synthases. Pharmacol. Ther. 2010, 128:499-508. http://dx.doi.org/10.1016/j.pharmthera.2010.08.010.
    • (2010) Pharmacol. Ther. , vol.128 , pp. 499-508
    • Tsutsui, M.1    Shimokawa, H.2    Otsuji, Y.3    Yanagihara, N.4
  • 178
    • 84920054130 scopus 로고    scopus 로고
    • The Keap1-Nrf2 system and diabetes mellitus
    • Uruno A., Yagishita Y., Yamamoto M. The Keap1-Nrf2 system and diabetes mellitus. Arch. Biochem. Biophys. 2015, 566:76-84. http://dx.doi.org/10.1016/j.abb.2014.12.012.
    • (2015) Arch. Biochem. Biophys. , vol.566 , pp. 76-84
    • Uruno, A.1    Yagishita, Y.2    Yamamoto, M.3
  • 179
    • 84919788547 scopus 로고    scopus 로고
    • Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy
    • Varga Z.V., Giricz Z., Liaudet L., Haskó G., Ferdinandy P., Pacher P. Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy. Biochim. Biophys. Acta 2015, 1852:232-242. http://dx.doi.org/10.1016/j.bbadis.2014.06.030.
    • (2015) Biochim. Biophys. Acta , vol.1852 , pp. 232-242
    • Varga, Z.V.1    Giricz, Z.2    Liaudet, L.3    Haskó, G.4    Ferdinandy, P.5    Pacher, P.6
  • 180
    • 84883616680 scopus 로고    scopus 로고
    • Oxidative stress in aging-matters of the heart and mind
    • Venkataraman K., Khurana S., Tai T. Oxidative stress in aging-matters of the heart and mind. Int. J. Mol. Sci. 2013, 14:17897-17925. http://dx.doi.org/10.3390/ijms140917897.
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 17897-17925
    • Venkataraman, K.1    Khurana, S.2    Tai, T.3
  • 181
    • 84870239255 scopus 로고    scopus 로고
    • Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults
    • Walker A.E., Kaplon R.E., Lucking S.M., Russell-Nowlan M.J., Eckel R.H., Seals D.R. Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults. Hypertension 2012, 60:1517-1523. http://dx.doi.org/10.1161/hypertensionaha.112.203661.
    • (2012) Hypertension , vol.60 , pp. 1517-1523
    • Walker, A.E.1    Kaplon, R.E.2    Lucking, S.M.3    Russell-Nowlan, M.J.4    Eckel, R.H.5    Seals, D.R.6
  • 182
    • 84867738060 scopus 로고    scopus 로고
    • Mitochondria as a drug target in ischemic heart disease and cardiomyopathy
    • Walters A.M., Porter G.A., Brookes P.S. Mitochondria as a drug target in ischemic heart disease and cardiomyopathy. Circ. Res. 2012, 111:1222-1236. http://dx.doi.org/10.1161/circresaha.112.265660.
    • (2012) Circ. Res. , vol.111 , pp. 1222-1236
    • Walters, A.M.1    Porter, G.A.2    Brookes, P.S.3
  • 184
    • 77349124428 scopus 로고    scopus 로고
    • Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury
    • Wang Y., Lau W.B., Gao E., Tao L., Yuan Y., Li R., Wang X., Koch W.J., Ma X.L. Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury. Am. J. Physiol. Endocrinol. Metab. 2010, 298:E663-E670. http://dx.doi.org/10.1152/ajpendo.00663.2009.
    • (2010) Am. J. Physiol. Endocrinol. Metab. , vol.298 , pp. E663-E670
    • Wang, Y.1    Lau, W.B.2    Gao, E.3    Tao, L.4    Yuan, Y.5    Li, R.6    Wang, X.7    Koch, W.J.8    Ma, X.L.9
  • 185
    • 84862509994 scopus 로고    scopus 로고
    • Resveratrol in cardiovascular disease: what is known from current research?
    • Wang H., Yang Y.J., Qian H.Y., Zhang Q., Xu H., Li J.J. Resveratrol in cardiovascular disease: what is known from current research?. Heart Fail. Rev. 2012, 17:437-448. http://dx.doi.org/10.1007/s10741-011-9260-4.
    • (2012) Heart Fail. Rev. , vol.17 , pp. 437-448
    • Wang, H.1    Yang, Y.J.2    Qian, H.Y.3    Zhang, Q.4    Xu, H.5    Li, J.J.6
  • 186
    • 84864287866 scopus 로고    scopus 로고
    • Chronic matrix metalloproteinase inhibition retards age-associated arterial proinflammation and increase in blood pressure
    • Wang M., Zhang J., Telljohann R., Jiang L., Wu J., Monticone R.E., Kapoor K., Talan M., Lakatta E.G. Chronic matrix metalloproteinase inhibition retards age-associated arterial proinflammation and increase in blood pressure. Hypertension 2012, 60:459-466. http://dx.doi.org/10.1161/hypertensionaha.112.191270.
    • (2012) Hypertension , vol.60 , pp. 459-466
    • Wang, M.1    Zhang, J.2    Telljohann, R.3    Jiang, L.4    Wu, J.5    Monticone, R.E.6    Kapoor, K.7    Talan, M.8    Lakatta, E.G.9
  • 187
    • 79952600167 scopus 로고    scopus 로고
    • Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: influence of age at onset, diabetes duration, and established and novel risk factors
    • Wannamethee S.G., Shaper A.G., Whincup P.H., Lennon L., Sattar N. Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: influence of age at onset, diabetes duration, and established and novel risk factors. Arch. Intern. Med. 2011, 171:404-410. http://dx.doi.org/10.1001/archinternmed.2011.2.
    • (2011) Arch. Intern. Med. , vol.171 , pp. 404-410
    • Wannamethee, S.G.1    Shaper, A.G.2    Whincup, P.H.3    Lennon, L.4    Sattar, N.5
  • 188
    • 84884708928 scopus 로고    scopus 로고
    • Plasma vitamin C, but not vitamin E, is associated with reduced risk of heart failure in older men
    • Wannamethee S.G., Bruckdorfer K.R., Shaper A.G., Papacosta O., Lennon L., Whincup P.H. Plasma vitamin C, but not vitamin E, is associated with reduced risk of heart failure in older men. Circ. Heart Fail. 2013, 6:647-654. http://dx.doi.org/10.1161/circheartfailure.112.000281.
    • (2013) Circ. Heart Fail. , vol.6 , pp. 647-654
    • Wannamethee, S.G.1    Bruckdorfer, K.R.2    Shaper, A.G.3    Papacosta, O.4    Lennon, L.5    Whincup, P.H.6
  • 189
    • 84926188428 scopus 로고    scopus 로고
    • Evaluating the safety and efficacy of sodium-restricted/dietary approaches to stop hypertension diet after acute decompensated heart failure hospitalization: design and rationale for the geriatric out of hospital randomized meal trial in heart failure (GOURMET-HF)
    • e4
    • Wessler J.D., Maurer M.S., Hummel S.L. Evaluating the safety and efficacy of sodium-restricted/dietary approaches to stop hypertension diet after acute decompensated heart failure hospitalization: design and rationale for the geriatric out of hospital randomized meal trial in heart failure (GOURMET-HF). Am. Heart J. 2015, 169:342-348. e4. http://dx.doi.org/10.1016/j.ahj.2014.11.021.
    • (2015) Am. Heart J. , vol.169 , pp. 342-348
    • Wessler, J.D.1    Maurer, M.S.2    Hummel, S.L.3
  • 190
  • 191
    • 77649162855 scopus 로고    scopus 로고
    • Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease
    • Willis M.S., Townley-Tilson W.H., Kang E.Y., Homeister J.W., Patterson C. Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease. Circ. Res. 2010, 106:463-478. http://dx.doi.org/10.1161/circresaha.109.208801.
    • (2010) Circ. Res. , vol.106 , pp. 463-478
    • Willis, M.S.1    Townley-Tilson, W.H.2    Kang, E.Y.3    Homeister, J.W.4    Patterson, C.5
  • 193
    • 0141799801 scopus 로고    scopus 로고
    • Manifestations of aging at the cytogenetic level
    • Wojda A., Witt M. Manifestations of aging at the cytogenetic level. J. Appl. Genet. 2003, 44:383-399.
    • (2003) J. Appl. Genet. , vol.44 , pp. 383-399
    • Wojda, A.1    Witt, M.2
  • 194
    • 84155172822 scopus 로고    scopus 로고
    • Ischemic preconditioning: the role of mitochondria and aging
    • Wojtovich A.P., Nadtochiy S.M., Brookes P.S., Nehrke K. Ischemic preconditioning: the role of mitochondria and aging. Exp. Gerontol. 2012, 47:1-7. http://dx.doi.org/10.1016/j.exger.2011.11.001.
    • (2012) Exp. Gerontol. , vol.47 , pp. 1-7
    • Wojtovich, A.P.1    Nadtochiy, S.M.2    Brookes, P.S.3    Nehrke, K.4
  • 195
    • 84957550234 scopus 로고    scopus 로고
    • Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy
    • e0125726
    • Wu C.C., Huang Y.S., Chen J.S., Huang C.F., Su S.L., Lu K.C., Lin Y.F., Chu P., Lin S.H., Sytwu H.K. Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy. PLoS One 2015, 10:e0125726. http://dx.doi.org/10.1371/journal.pone.0125726.
    • (2015) PLoS One , vol.10
    • Wu, C.C.1    Huang, Y.S.2    Chen, J.S.3    Huang, C.F.4    Su, S.L.5    Lu, K.C.6    Lin, Y.F.7    Chu, P.8    Lin, S.H.9    Sytwu, H.K.10
  • 196
    • 84870361939 scopus 로고    scopus 로고
    • Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice
    • Xu J., Kulkarni S.R., Donepudi A.C., More V.R., Slitt A.L. Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice. Diabetes 2012, 61:3208-3218. http://dx.doi.org/10.2337/db11-1716.
    • (2012) Diabetes , vol.61 , pp. 3208-3218
    • Xu, J.1    Kulkarni, S.R.2    Donepudi, A.C.3    More, V.R.4    Slitt, A.L.5
  • 197
    • 84927650894 scopus 로고    scopus 로고
    • Role of the Keap1/Nrf2 pathway in neurodegenerative diseases
    • Yamazaki H., Tanji K., Wakabayashi K., Matsuura S., Itoh K. Role of the Keap1/Nrf2 pathway in neurodegenerative diseases. Pathol. Int. 2015, 65:210-219. http://dx.doi.org/10.1111/pin.12261.
    • (2015) Pathol. Int. , vol.65 , pp. 210-219
    • Yamazaki, H.1    Tanji, K.2    Wakabayashi, K.3    Matsuura, S.4    Itoh, K.5
  • 198
    • 84929166089 scopus 로고    scopus 로고
    • Evaluation of the protective effects of curcuminoid (curcumin and bisdemethoxycurcumin)-loaded liposomes against bone turnover in a cell-based model of osteoarthritis
    • Yeh C.C., Su Y.H., Lin Y.J., Chen P.J., Shi C.S., Chen C.N., Chang H.I. Evaluation of the protective effects of curcuminoid (curcumin and bisdemethoxycurcumin)-loaded liposomes against bone turnover in a cell-based model of osteoarthritis. Drug Des. Dev. Ther. 2015, 9:2285-2300. http://dx.doi.org/10.2147/DDDT.S78277.
    • (2015) Drug Des. Dev. Ther. , vol.9 , pp. 2285-2300
    • Yeh, C.C.1    Su, Y.H.2    Lin, Y.J.3    Chen, P.J.4    Shi, C.S.5    Chen, C.N.6    Chang, H.I.7
  • 199
    • 84869208408 scopus 로고    scopus 로고
    • Positive crosstalk between arginase-II and S6K1 in vascular endothelial inflammation and aging
    • Yepuri G., Velagapudi S., Xiong Y., Rajapakse A.G., Montani J.P., Ming X.F., Yang Z. Positive crosstalk between arginase-II and S6K1 in vascular endothelial inflammation and aging. Aging Cell 2012, 11:1005-1016. http://dx.doi.org/10.1111/acel.12001.
    • (2012) Aging Cell , vol.11 , pp. 1005-1016
    • Yepuri, G.1    Velagapudi, S.2    Xiong, Y.3    Rajapakse, A.G.4    Montani, J.P.5    Ming, X.F.6    Yang, Z.7
  • 200
    • 84931359321 scopus 로고    scopus 로고
    • Resveratrol attenuated low ambient temperature-induced myocardial hypertrophy via inhibiting cardiomyocyte apoptosis
    • Yin K., Zhao L., Feng D., Ma W., Liu Y., Wang Y., Liang J., Yang F., Bi C., Chen H., Li X., Lu Y., Cai B. Resveratrol attenuated low ambient temperature-induced myocardial hypertrophy via inhibiting cardiomyocyte apoptosis. Cell. Physiol. Biochem. 2015, 35:2451-2462. http://dx.doi.org/10.1159/000374045.
    • (2015) Cell. Physiol. Biochem. , vol.35 , pp. 2451-2462
    • Yin, K.1    Zhao, L.2    Feng, D.3    Ma, W.4    Liu, Y.5    Wang, Y.6    Liang, J.7    Yang, F.8    Bi, C.9    Chen, H.10    Li, X.11    Lu, Y.12    Cai, B.13
  • 201
    • 84942797497 scopus 로고    scopus 로고
    • The hippo pathway in heart development, regeneration, and diseases
    • Zhou Q., Li L., Zhao B., Guan K.L. The hippo pathway in heart development, regeneration, and diseases. Circ. Res. 2015, 116:1431-1447. http://dx.doi.org/10.1161/circresaha.116.303311.
    • (2015) Circ. Res. , vol.116 , pp. 1431-1447
    • Zhou, Q.1    Li, L.2    Zhao, B.3    Guan, K.L.4
  • 202
    • 33646055216 scopus 로고    scopus 로고
    • The role of oxidants and free radicals in reperfusion injury
    • Zweier J.L., Talukder M.A. The role of oxidants and free radicals in reperfusion injury. Cardiovasc. Res. 2006, 70:181-190.
    • (2006) Cardiovasc. Res. , vol.70 , pp. 181-190
    • Zweier, J.L.1    Talukder, M.A.2


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