Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway

Neuroscience

Volumn 260, Issue , 2014, Pages 130-139

  Colin Gonzalez A L ^a   Luna Lopez A ^b   Konigsberg M ^c   Ali, S F ^d   Pedraza Chaverri J ^e   Santamaria A ^a  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b INSTITUTO NACIONAL DE GERIATRÍA   (Mexico)

^c DEPARTAMENTO DE QUÍMICA   (Mexico)

^d NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^e UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Antioxidant defense; Excitotoxicity; Kynurenine pathway; Nrf2; Oxidative stress

Indexed keywords

GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; KYNURENINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; QUINOLINIC ACID; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DAMAGE; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS STRIATUM; INCUBATION TIME; KNOCKOUT MOUSE; LIPID PEROXIDATION; MALE; MOUSE; NEUROMODULATION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; SPECIES DIFFERENCE; TIME SERIES ANALYSIS; UPREGULATION; WILD TYPE;

ANTIOXIDANT DEFENSE; ANTIOXIDANT RESPONSE ELEMENT; ARE; DIMETHYLFUMARATE; DIZOCILPINE; DMF; EDTA; EGTA; ETHYLENE GLYCOL TETRAACETIC ACID; ETHYLENEDIAMINETETRAACETIC ACID; EXCITOTOXICITY; GAMMA-GLUTAMYLCYSTEINE LIGASE-C; HD; HEME OXYGENASE-1; HEPES; HO-1; HUNTINGTON'S DISEASE; HYDROXYETHYL PIPERAZINEETHANESULFONIC ACID; KP; KYNURENINE PATHWAY; MALONDIALDEHYDE; MDA; MK-801; N-METHYL-D-ASPARTATE RECEPTOR; NAD(P)H; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE-OXIDASE; NMDAR; NRF2; NUCLEAR FACTOR (ERYTHROID-DERIVED 2)-LIKE 2; OXIDATIVE STRESS; QUIN; QUINOLINIC ACID; REACTIVE OXYGEN SPECIES; ROS; S-ALLYL CYSTEINE; SAC; SOD; SUPEROXIDE DISMUTASE; TBARS; TBHQ; TERT-BUTYLHYDROQUINONE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; Γ-GCL-C;

ANIMALS; CORPUS STRIATUM; FEMALE; HUMANS; KYNURENINE; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; QUINOLINIC ACID; RATS; RATS, WISTAR;

EID: 84892470019     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.12.025     Document Type: Article

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