-
1
-
-
0037237927
-
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
-
Ischiropoulos, H.; Beckman, J. S., Oxidative stress and nitration in neurodegeneration: cause, effect, or association? J. Clin. Invest., 2003, 111, 163-169.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 163-169
-
-
Ischiropoulos, H.1
Beckman, J.S.2
-
2
-
-
52049099354
-
Role of oxidative stress and nitric oxide in atherothrombosis
-
Lubos, E.; Handy, D. E.; Loscalzo, J. Role of oxidative stress and nitric oxide in atherothrombosis. Front Biosci., 2008, 13, 5323-5344.
-
(2008)
Front Biosci.
, vol.13
, pp. 5323-5344
-
-
Lubos, E.1
Handy, D.E.2
Loscalzo, J.3
-
3
-
-
33745039466
-
Nitric oxide cell bioenergetics and neurodegeneration
-
Moncada, S.; Bolanos, J. P. Nitric oxide cell bioenergetics and neurodegeneration. J. Neurochem., 2006, 97, 1676-1689.
-
(2006)
J. Neurochem.
, vol.97
, pp. 1676-1689
-
-
Moncada, S.1
Bolanos, J.P.2
-
4
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
Pacher, P.; Beckman, J. S.; Liaudet, L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev., 2007, 87, 315-424.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
5
-
-
33644834586
-
Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes
-
DOI 10.1016/j.coph.2006.01.001, PII S147148920600018X
-
Pacher, P.; Szabo, C. Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes. Curr. Opin. Pharmacol., 2006, 6, 136-141. (Pubitemid 43362126)
-
(2006)
Current Opinion in Pharmacology
, vol.6
, Issue.2
, pp. 136-141
-
-
Pacher, P.1
Szabo, C.2
-
6
-
-
41349096436
-
Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension
-
Schulz, E.; Jansen, T.; Wenzel, P.; Daiber, A.; Munzel, T. Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension. Antioxid. Redox. Signal., 2008, 10, 1115-1126.
-
(2008)
Antioxid. Redox. Signal.
, vol.10
, pp. 1115-1126
-
-
Schulz, E.1
Jansen, T.2
Wenzel, P.3
Daiber, A.4
Munzel, T.5
-
7
-
-
34547673497
-
Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
-
Szabo, C.; Ischiropoulos, H.; Radi, R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat. Rev. Drug Discov., 2007, 6, 662-680.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 662-680
-
-
Szabo, C.1
Ischiropoulos, H.2
Radi, R.3
-
8
-
-
0036391974
-
Poly (ADP-ribose) polymerase is a regulator of chemokine production: Relevance for the pathogenesis of shock and inflammation
-
Hasko, G.; Mabley, J. G.; Nemeth, Z. H.; Pacher, P.; Deitch, E. A.; Szabo, C. Poly (ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation. Mol. Med., 2002, 8, 283-289.
-
(2002)
Mol. Med.
, vol.8
, pp. 283-289
-
-
Hasko, G.1
Mabley, J.G.2
Nemeth, Z.H.3
Pacher, P.4
Deitch, E.A.5
Szabo, C.6
-
9
-
-
14544297961
-
Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies
-
Pacher, P.; Obrosova, I. G.; Mabley, J. G.; Szabo, C. Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies. Curr. Med. Chem., 2005, 12, 267-275.
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 267-275
-
-
Pacher, P.1
Obrosova, I.G.2
Mabley, J.G.3
Szabo, C.4
-
10
-
-
63849103058
-
Role of peroxynitrite in the redox regulation of cell signal transduction pathways
-
Liaudet, L.; Vassalli, G.; Pacher, P. Role of peroxynitrite in the redox regulation of cell signal transduction pathways. Front Biosci., 2009, 14, 4809-4814.
-
(2009)
Front Biosci.
, vol.14
, pp. 4809-4814
-
-
Liaudet, L.1
Vassalli, G.2
Pacher, P.3
-
11
-
-
0025189864
-
Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
-
Beckman, J. S.; Beckman, T. W.; Chen, J.; Marshall, P. A.; Freeman, B. A. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U. S. A., 1990, 87, 1620-1624.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 1620-1624
-
-
Beckman, J.S.1
Beckman, T.W.2
Chen, J.3
Marshall, P.A.4
Freeman, B.A.5
-
13
-
-
0032789444
-
Nitric oxide: A unique endogenous signaling molecule in vascular biology
-
Ignarro, L. J. Nitric oxide: a unique endogenous signaling molecule in vascular biology. Biosci. Rep., 1999, 19, 51-71.
-
(1999)
Biosci. Rep.
, vol.19
, pp. 51-71
-
-
Ignarro, L.J.1
-
14
-
-
0032707717
-
Nitric oxide as a signaling molecule in the vascular system: An overview
-
Ignarro, L. J.; Cirino, G.; Casini, A.; Napoli, C. Nitric oxide as a signaling molecule in the vascular system: an overview. J. Cardiovasc. Pharmacol., 1999, 34, 879-886.
-
(1999)
J. Cardiovasc. Pharmacol.
, vol.34
, pp. 879-886
-
-
Ignarro, L.J.1
Cirino, G.2
Casini, A.3
Napoli, C.4
-
15
-
-
0036677518
-
Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions
-
Joshi, M. S.; Ferguson, T. B., Jr.; Han, T. H.; Hyduke, D. R.; Liao, J. C.; Rassaf, T.; Bryan, N.; Feelisch, M.; Lancaster, J. R., Jr. Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions. Proc. Natl. Acad. Sci. U. S. A., 2002, 99, 10341-10346.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 10341-10346
-
-
Joshi, M.S.1
Ferguson Jr., T.B.2
Han, T.H.3
Hyduke, D.R.4
Liao, J.C.5
Rassaf, T.6
Bryan, N.7
Feelisch, M.8
Lancaster Jr., J.R.9
-
16
-
-
0037172177
-
The rate constant of the reaction of superoxide with nitrogen monoxide: Approaching the diffusion limit
-
Nauser, T.; Koppenol, W. H. The rate constant of the reaction of superoxide with nitrogen monoxide: Approaching the diffusion limit. J. Phys. Chem. A., 2002, 106, 4084-4086.
-
(2002)
J. Phys. Chem. A.
, vol.106
, pp. 4084-4086
-
-
Nauser, T.1
Koppenol, W.H.2
-
17
-
-
0026500329
-
Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide
-
Hogg, N.; Darley-Usmar, V. M.; Wilson, M. T.; Moncada, S. Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide. Biochem. J., 1992, 281, 419-424.
-
(1992)
Biochem. J.
, vol.281
, pp. 419-424
-
-
Hogg, N.1
Darley-Usmar, V.M.2
Wilson, M.T.3
Moncada, S.4
-
18
-
-
0031816583
-
Formation of spin trap adducts during the decomposition of peroxynitrite
-
Gatti, R. M.; Alvarez, B.; Vasquez-Vivar, J.; Radi, R.; Augusto, O. Formation of spin trap adducts during the decomposition of peroxynitrite. Arch. Biochem. Biophys., 1998, 349, 36-46.
-
(1998)
Arch. Biochem. Biophys.
, vol.349
, pp. 36-46
-
-
Gatti, R.M.1
Alvarez, B.2
Vasquez-Vivar, J.3
Radi, R.4
Augusto, O.5
-
19
-
-
0033567373
-
Radical mechanisms of the decomposition of peroxynitrite and the peroxynitrite-CO (2) adduct and of reactions with L-tyrosine and related compounds as studied by (15) N chemically induced dynamic nuclear polarization
-
Lehnig, M. Radical mechanisms of the decomposition of peroxynitrite and the peroxynitrite-CO (2) adduct and of reactions with L-tyrosine and related compounds as studied by (15) N chemically induced dynamic nuclear polarization. Arch. Biochem. Biophys., 1999, 368, 303-318.
-
(1999)
Arch. Biochem. Biophys.
, vol.368
, pp. 303-318
-
-
Lehnig, M.1
-
21
-
-
0031826286
-
Peroxynitrite reactions and diffusion in biology
-
Radi, R. Peroxynitrite reactions and diffusion in biology. Chem. Res. Toxicol., 1998, 11, 720-721.
-
(1998)
Chem. Res. Toxicol.
, vol.11
, pp. 720-721
-
-
Radi, R.1
-
22
-
-
0032147208
-
Biological tyrosine nitration: A pathophysiological function of nitric oxide and reactive oxygen species
-
Ischiropoulos, H. Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch. Biochem. Biophys., 1998, 356, 1-11.
-
(1998)
Arch. Biochem. Biophys.
, vol.356
, pp. 1-11
-
-
Ischiropoulos, H.1
-
23
-
-
0038731081
-
Biological selectivity and functional aspects of protein tyrosine nitration
-
Ischiropoulos, H. Biological selectivity and functional aspects of protein tyrosine nitration. Biochem. Biophys. Res. Commun., 2003, 305, 776-783.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.305
, pp. 776-783
-
-
Ischiropoulos, H.1
-
24
-
-
0025363999
-
Ischaemic injury mediator
-
Beckman, J. S. Ischaemic injury mediator. Nature, 1990, 345, 27-28.
-
(1990)
Nature
, vol.345
, pp. 27-28
-
-
Beckman, J.S.1
-
25
-
-
0029682870
-
Oxidative damage and tyrosine nitration from peroxynitrite
-
Beckman, J. S. Oxidative damage and tyrosine nitration from peroxynitrite. Chem. Res. Toxicol., 1996, 9, 836-844.
-
(1996)
Chem. Res. Toxicol.
, vol.9
, pp. 836-844
-
-
Beckman, J.S.1
-
26
-
-
0026676388
-
The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein
-
Darley-Usmar, V. M.; Hogg, N.; O'Leary, V. J.; Wilson, M. T.; Moncada, S. The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein. Free Radic. Res. Commun., 1992, 17, 9-20.
-
(1992)
Free Radic. Res. Commun.
, vol.17
, pp. 9-20
-
-
Darley-Usmar, V.M.1
Hogg, N.2
O'Leary, V.J.3
Wilson, M.T.4
Moncada, S.5
-
27
-
-
0035282582
-
Unraveling peroxynitrite formation in biological systems
-
Radi, R.; Peluffo, G.; Alvarez, M. N.; Naviliat, M.; Cayota, A. Unraveling peroxynitrite formation in biological systems. Free. Radic. Biol. Med., 2001, 30, 463-488.
-
(2001)
Free. Radic. Biol. Med.
, vol.30
, pp. 463-488
-
-
Radi, R.1
Peluffo, G.2
Alvarez, M.N.3
Naviliat, M.4
Cayota, A.5
-
28
-
-
0032171410
-
Oxidative chemistry of nitric oxide: The roles of superoxide, peroxynitrite, and carbon dioxide
-
Squadrito, G. L.; Pryor, W. A. Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide. Free. Radic. Biol. Med., 1998, 25, 392-403.
-
(1998)
Free. Radic. Biol. Med.
, vol.25
, pp. 392-403
-
-
Squadrito, G.L.1
Pryor, W.A.2
-
29
-
-
0036569412
-
Nitrogen dioxide and carbonate radical anion: Two emerging radicals in biology
-
Augusto, O.; Bonini, M. G.; Amanso, A. M.; Linares, E.; Santos, C. C.; De Menezes, S. L. Nitrogen dioxide and carbonate radical anion: two emerging radicals in biology. Free Radic. Biol. Med., 2002, 32, 841-859.
-
(2002)
Free Radic. Biol. Med.
, vol.32
, pp. 841-859
-
-
Augusto, O.1
Bonini, M.G.2
Amanso, A.M.3
Linares, E.4
Santos, C.C.5
De Menezes, S.L.6
-
30
-
-
0030249458
-
Peroxynitrite reaction with carbon dioxide/bicarbonate: Kinetics and influence on peroxynitrite-mediated oxidations
-
Denicola, A.; Freeman, B. A.; Trujillo, M.; Radi, R. Peroxynitrite reaction with carbon dioxide/bicarbonate: kinetics and influence on peroxynitrite-mediated oxidations. Arch. Biochem. Biophys., 1996, 333, 49-58.
-
(1996)
Arch. Biochem. Biophys.
, vol.333
, pp. 49-58
-
-
Denicola, A.1
Freeman, B.A.2
Trujillo, M.3
Radi, R.4
-
31
-
-
0029680493
-
Carbon dioxide: Physiological catalyst for peroxynitrite-mediated cellular damage or cellular protectant?
-
Lymar, S. V.; Hurst, J. K. Carbon dioxide: physiological catalyst for peroxynitrite-mediated cellular damage or cellular protectant? Chem. Res. Toxicol., 1996, 9, 845-850.
-
(1996)
Chem. Res. Toxicol.
, vol.9
, pp. 845-850
-
-
Lymar, S.V.1
Hurst, J.K.2
-
32
-
-
0027413240
-
Peroxynitrite-induced luminol chemiluminescence
-
Radi, R.; Cosgrove, T. P.; Beckman, J. S.; Freeman, B. A. Peroxynitrite-induced luminol chemiluminescence. Biochem. J., 1993, 290, 51-57.
-
(1993)
Biochem. J.
, vol.290
, pp. 51-57
-
-
Radi, R.1
Cosgrove, T.P.2
Beckman, J.S.3
Freeman, B.A.4
-
33
-
-
0029953744
-
Mechanism of carbon dioxidecatalyzed oxidation of tyrosine by peroxynitrite
-
Lymar, S. V.; Jiang, Q.; Hurst, J. K. Mechanism of carbon dioxidecatalyzed oxidation of tyrosine by peroxynitrite. Biochemistry, 1996, 35, 7855-7861.
-
(1996)
Biochemistry
, vol.35
, pp. 7855-7861
-
-
Lymar, S.V.1
Jiang, Q.2
Hurst, J.K.3
-
34
-
-
0035971225
-
Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite
-
Bonini, M. G.; Augusto, O. Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite. J. Biol. Chem., 2001, 276, 9749-9754.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9749-9754
-
-
Bonini, M.G.1
Augusto, O.2
-
35
-
-
0034603053
-
Tyrosine nitration by simultaneous generation of (.) NO and O-(2) under physiological conditions. How the radicals do the job
-
Goldstein, S.; Czapski, G.; Lind, J.; Merenyi, G. Tyrosine nitration by simultaneous generation of (.) NO and O-(2) under physiological conditions. How the radicals do the job. J. Biol. Chem., 2000, 275, 3031-3036.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3031-3036
-
-
Goldstein, S.1
Czapski, G.2
Lind, J.3
Merenyi, G.4
-
36
-
-
0034193163
-
Role of the carbonate radical anion in tyrosine nitration and hydroxylation by peroxynitrite
-
Santos, C. X.; Bonini, M. G.; Augusto, O. Role of the carbonate radical anion in tyrosine nitration and hydroxylation by peroxynitrite. Arch. Biochem. Biophys., 2000, 377, 146-152.
-
(2000)
Arch. Biochem. Biophys.
, vol.377
, pp. 146-152
-
-
Santos, C.X.1
Bonini, M.G.2
Augusto, O.3
-
37
-
-
0031460696
-
Peroxynitrite rapidly permeates phospholipid membranes
-
Marla, S. S.; Lee, J.; Groves, J. T. Peroxynitrite rapidly permeates phospholipid membranes. Proc. Natl. Acad. Sci. U. S. A., 1997, 94, 14243-14248.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 14243-14248
-
-
Marla, S.S.1
Lee, J.2
Groves, J.T.3
-
38
-
-
0033179574
-
Diffusion of peroxynitrite in the presence of carbon dioxide
-
Romero, N.; Denicola, A.; Souza, J. M.; Radi, R. Diffusion of peroxynitrite in the presence of carbon dioxide. Arch. Biochem. Biophys., 1999, 368, 23-30.
-
(1999)
Arch. Biochem. Biophys.
, vol.368
, pp. 23-30
-
-
Romero, N.1
Denicola, A.2
Souza, J.M.3
Radi, R.4
-
39
-
-
0034700236
-
Permeation of phospholipid membranes by peroxynitrite
-
Khairutdinov, R. F.; Coddington, J. W.; Hurst, J. K. Permeation of phospholipid membranes by peroxynitrite. Biochemistry., 2000, 39, 14238-14249.
-
(2000)
Biochemistry.
, vol.39
, pp. 14238-14249
-
-
Khairutdinov, R.F.1
Coddington, J.W.2
Hurst, J.K.3
-
40
-
-
0035955646
-
EPR detection of glutathionyl and protein-tyrosyl radicals during the interaction of peroxynitrite with macrophages (J774)
-
Lopes de Menezes, S.; Augusto, O. EPR detection of glutathionyl and protein-tyrosyl radicals during the interaction of peroxynitrite with macrophages (J774). J. Biol. Chem., 2001, 276, 39879-39884.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39879-39884
-
-
Lopes De Menezes, S.1
Augusto, O.2
-
41
-
-
0032584141
-
Diffusion of peroxynitrite across erythrocyte membranes
-
Denicola, A.; Souza, J. M.; Radi, R. Diffusion of peroxynitrite across erythrocyte membranes. Proc. Natl. Acad. Sci. U. S. A., 1998, 95, 3566-3571.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 3566-3571
-
-
Denicola, A.1
Souza, J.M.2
Radi, R.3
-
42
-
-
0033017612
-
A novel superoxide dismutase-based trap for peroxynitrite used to detect entry of peroxynitrite into erythrocyte ghosts
-
Macfadyen, A. J.; Reiter, C.; Zhuang, Y.; Beckman, J. S. A novel superoxide dismutase-based trap for peroxynitrite used to detect entry of peroxynitrite into erythrocyte ghosts. Chem. Res. Toxicol., 1999, 12, 223-229.
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 223-229
-
-
Macfadyen, A.J.1
Reiter, C.2
Zhuang, Y.3
Beckman, J.S.4
-
43
-
-
33749005136
-
Nitroxidative, nitrosative, and nitrative stress: Kinetic predictions of reactive nitrogen species chemistry under biological conditions
-
Lancaster, J. R., Jr. Nitroxidative, nitrosative, and nitrative stress: kinetic predictions of reactive nitrogen species chemistry under biological conditions. Chem. Res. Toxicol., 2006, 19, 1160-1174.
-
(2006)
Chem. Res. Toxicol.
, vol.19
, pp. 1160-1174
-
-
Lancaster Jr., J.R.1
-
44
-
-
0035954378
-
Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: Comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution
-
Zhang, H.; Joseph, J.; Feix, J.; Hogg, N.; Kalyanaraman, B. Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution. Biochemistry, 2001, 40, 7675-7686.
-
(2001)
Biochemistry
, vol.40
, pp. 7675-7686
-
-
Zhang, H.1
Joseph, J.2
Feix, J.3
Hogg, N.4
Kalyanaraman, B.5
-
45
-
-
0036890524
-
Peroxynitrite reactions and formation in mitochondria
-
Radi, R.; Cassina, A.; Hodara, R.; Quijano, C.; Castro, L. Peroxynitrite reactions and formation in mitochondria. Free Radic. Biol. Med., 2002, 33, 1451-1464.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1451-1464
-
-
Radi, R.1
Cassina, A.2
Hodara, R.3
Quijano, C.4
Castro, L.5
-
46
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
-
Wild, S.; Roglic, G.; Green, A.; Sicree, R.; King, H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care, 2004, 27, 1047-1053.
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
47
-
-
28844466951
-
Diabetic retinopathy: Mitochondrial dysfunction and retinal capillary cell death
-
Kowluru, R. A. Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death. Antioxid. Redox. Signal., 2005, 7, 1581-1587.
-
(2005)
Antioxid. Redox. Signal.
, vol.7
, pp. 1581-1587
-
-
Kowluru, R.A.1
-
48
-
-
34247394257
-
Oxidative stress and diabetic retinopathy
-
Kowluru, R. A.; Chan, P. S. Oxidative stress and diabetic retinopathy. Exp. Diabetes Res., 2007, 2007, 43603.
-
(2007)
Exp. Diabetes Res.
, vol.2007
, pp. 43603
-
-
Kowluru, R.A.1
Chan, P.S.2
-
49
-
-
30344486998
-
Oxidative stress and diabetic cardiovascular complications
-
Jay, D.; Hitomi, H.; Griendling, K. K. Oxidative stress and diabetic cardiovascular complications. Free Radic. Biol. Med., 2006, 40, 183-192.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 183-192
-
-
Jay, D.1
Hitomi, H.2
Griendling, K.K.3
-
50
-
-
21644484482
-
Role of nitrosative stress and poly (ADP-ribose) polymerase activation in diabetic vascular dysfunction
-
Mabley, J. G.; Soriano, F. G. Role of nitrosative stress and poly (ADP-ribose) polymerase activation in diabetic vascular dysfunction. Curr. Vasc. Pharmacol., 2005, 3, 247-252.
-
(2005)
Curr. Vasc. Pharmacol.
, vol.3
, pp. 247-252
-
-
Mabley, J.G.1
Soriano, F.G.2
-
51
-
-
70349297369
-
Diabetes and the peripheral nerve
-
Obrosova, I. G. Diabetes and the peripheral nerve. Biochim. Biophys. Acta, 2009, 1792, 931-940.
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 931-940
-
-
Obrosova, I.G.1
-
52
-
-
33644681565
-
Oxidative-nitrosative stress and poly (ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: The relation is revisited
-
Obrosova, I. G.; Drel, V. R.; Pacher, P.; Ilnytska, O.; Wang, Z. Q.; Stevens, M. J.; Yorek, M. A. Oxidative-nitrosative stress and poly (ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited. Diabetes, 2005, 54, 3435-3441.
-
(2005)
Diabetes
, vol.54
, pp. 3435-3441
-
-
Obrosova, I.G.1
Drel, V.R.2
Pacher, P.3
Ilnytska, O.4
Wang, Z.Q.5
Stevens, M.J.6
Yorek, M.A.7
-
53
-
-
0032434935
-
Insulin secretion, DNA damage, and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite, and cytokines
-
Hadjivassiliou, V.; Green, M. H.; James, R. F.; Swift, S. M.; Clayton, H. A.; Green, I. C. Insulin secretion, DNA damage, and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite, and cytokines. Nitric Oxide, 1998, 2, 429-441.
-
(1998)
Nitric Oxide
, vol.2
, pp. 429-441
-
-
Hadjivassiliou, V.1
Green, M.H.2
James, R.F.3
Swift, S.M.4
Clayton, H.A.5
Green, I.C.6
-
54
-
-
0028283283
-
The effect of nitric oxide donors on insulin secretion, cyclic GMP and cyclic AMP in rat islets of Langerhans and the insulin-secreting cell lines HIT-T15 and RINm5F
-
Cunningham, J. M.; Mabley, J. G.; Delaney, C. A.; Green, I. C. The effect of nitric oxide donors on insulin secretion, cyclic GMP and cyclic AMP in rat islets of Langerhans and the insulin-secreting cell lines HIT-T15 and RINm5F. Mol. Cell Endocrinol., 1994, 102, 23-29.
-
(1994)
Mol. Cell. Endocrinol.
, vol.102
, pp. 23-29
-
-
Cunningham, J.M.1
Mabley, J.G.2
Delaney, C.A.3
Green, I.C.4
-
55
-
-
0029915909
-
Nitric oxide donors decrease the function and survival of human pancreatic islets
-
Eizirik, D. L.; Delaney, C. A.; Green, M. H.; Cunningham, J. M.; Thorpe, J. R.; Pipeleers, D. G.; Hellerstrom, C.; Green, I. C. Nitric oxide donors decrease the function and survival of human pancreatic islets. Mol. Cell Endocrinol., 1996, 118, 71-83.
-
(1996)
Mol. Cell. Endocrinol.
, vol.118
, pp. 71-83
-
-
Eizirik, D.L.1
Delaney, C.A.2
Green, M.H.3
Cunningham, J.M.4
Thorpe, J.R.5
Pipeleers, D.G.6
Hellerstrom, C.7
Green, I.C.8
-
56
-
-
0027536123
-
Islet cell DNA is a target of inflammatory attack by nitric oxide
-
Fehsel, K.; Jalowy, A.; Qi, S.; Burkart, V.; Hartmann, B.; Kolb, H. Islet cell DNA is a target of inflammatory attack by nitric oxide. Diabetes, 1993, 42, 496-500.
-
(1993)
Diabetes
, vol.42
, pp. 496-500
-
-
Fehsel, K.1
Jalowy, A.2
Qi, S.3
Burkart, V.4
Hartmann, B.5
Kolb, H.6
-
57
-
-
0033598713
-
Poly (ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
-
Ha, H. C.; Snyder, S. H. Poly (ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc. Natl. Acad. Sci. U. S. A., 1999, 96, 13978-13982.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 13978-13982
-
-
Ha, H.C.1
Snyder, S.H.2
-
58
-
-
0028276094
-
Nitric oxide toxicity in islet cells involves poly (ADP-ribose) polymerase activation and concomitant NAD+ depletion
-
Radons, J.; Heller, B.; Burkle, A.; Hartmann, B.; Rodriguez, M. L.; Kroncke, K. D.; Burkart, V.; Kolb, H. Nitric oxide toxicity in islet cells involves poly (ADP-ribose) polymerase activation and concomitant NAD+ depletion. Biochem. Biophys. Res. Commun., 1994, 199, 1270-1277.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.199
, pp. 1270-1277
-
-
Radons, J.1
Heller, B.2
Burkle, A.3
Hartmann, B.4
Rodriguez, M.L.5
Kroncke, K.D.6
Burkart, V.7
Kolb, H.8
-
59
-
-
19444377566
-
Roles of poly (ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications
-
Szabo, C. Roles of poly (ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications. Pharmacol. Res., 2005, 52, 60-71.
-
(2005)
Pharmacol. Res.
, vol.52
, pp. 60-71
-
-
Szabo, C.1
-
60
-
-
0029989197
-
Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: Identification of iNOS-expressing cells and relationships to cytokines expressed in the islets
-
Rabinovitch, A.; Suarez-Pinzon, W. L.; Sorensen, O.; Bleackley, R. C. Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: identification of iNOS-expressing cells and relationships to cytokines expressed in the islets. Endocrinology, 1996, 137, 2093-2099.
-
(1996)
Endocrinology
, vol.137
, pp. 2093-2099
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
Sorensen, O.3
Bleackley, R.C.4
-
61
-
-
0033041283
-
Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes
-
Flodstrom, M.; Tyrberg, B.; Eizirik, D. L.; Sandler, S. Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes. Diabetes, 1999, 48, 706-713.
-
(1999)
Diabetes
, vol.48
, pp. 706-713
-
-
Flodstrom, M.1
Tyrberg, B.2
Eizirik, D.L.3
Sandler, S.4
-
62
-
-
0030987135
-
Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells
-
Suarez-Pinzon, W. L.; Szabo, C.; Rabinovitch, A. Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells. Diabetes, 1997, 46, 907-911.
-
(1997)
Diabetes
, vol.46
, pp. 907-911
-
-
Suarez-Pinzon, W.L.1
Szabo, C.2
Rabinovitch, A.3
-
63
-
-
0034949349
-
An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice
-
Suarez-Pinzon, W. L.; Mabley, J. G.; Strynadka, K.; Power, R. F.; Szabo, C.; Rabinovitch, A. An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice. J. Autoimmun., 2001, 16, 449-455.
-
(2001)
J. Autoimmun.
, vol.16
, pp. 449-455
-
-
Suarez-Pinzon, W.L.1
Mabley, J.G.2
Strynadka, K.3
Power, R.F.4
Szabo, C.5
Rabinovitch, A.6
-
64
-
-
0036821898
-
Part I: Pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: Studies with FP15, a novel potent peroxynitrite decomposition catalyst
-
Szabo, C.; Mabley, J. G.; Moeller, S. M.; Shimanovich, R.; Pacher, P.; Virag, L.; Soriano, F. G.; Van Duzer, J. H.; Williams, W.; Salzman, A. L.; Groves, J. T. Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst. Mol. Med., 2002, 8, 571-580.
-
(2002)
Mol. Med.
, vol.8
, pp. 571-580
-
-
Szabo, C.1
Mabley, J.G.2
Moeller, S.M.3
Shimanovich, R.4
Pacher, P.5
Virag, L.6
Soriano, F.G.7
Van Duzer, J.H.8
Williams, W.9
Salzman, A.L.10
Groves, J.T.11
-
65
-
-
85047691537
-
Inhibition of GAPDH activity by poly (ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells
-
Du, X.; Matsumura, T.; Edelstein, D.; Rossetti, L.; Zsengeller, Z.; Szabo, C.; Brownlee, M. Inhibition of GAPDH activity by poly (ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J. Clin. Invest., 2003, 112, 1049-1057.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1049-1057
-
-
Du, X.1
Matsumura, T.2
Edelstein, D.3
Rossetti, L.4
Zsengeller, Z.5
Szabo, C.6
Brownlee, M.7
-
66
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee, M. Biochemistry and molecular cell biology of diabetic complications. Nature, 2001, 414, 813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
67
-
-
0032878326
-
Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes
-
Caballero, A. E.; Arora, S.; Saouaf, R.; Lim, S. C.; Smakowski, P.; Park, J. Y.; King, G. L.; Lo Gerfo, F. W.; Horton, E. S.; Veves, A. Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes. Diabetes, 1999, 48, 1856-1862.
-
(1999)
Diabetes
, vol.48
, pp. 1856-1862
-
-
Caballero, A.E.1
Arora, S.2
Saouaf, R.3
Lim, S.C.4
Smakowski, P.5
Park, J.Y.6
King, G.L.7
Lo Gerfo, F.W.8
Horton, E.S.9
Veves, A.10
-
68
-
-
0035116150
-
Diabetes and endothelial dysfunction: A clinical perspective
-
Calles-Escandon, J.; Cipolla, M. Diabetes and endothelial dysfunction: a clinical perspective. Endocr. Rev., 2001, 22, 36-52.
-
(2001)
Endocr. Rev.
, vol.22
, pp. 36-52
-
-
Calles-Escandon, J.1
Cipolla, M.2
-
69
-
-
4444265474
-
Antioxidant therapy in diabetic complications: What is new?
-
Da Ros, R.; Assaloni, R.; Ceriello, A. Antioxidant therapy in diabetic complications: what is new? Curr. Vasc. Pharmacol., 2004, 2, 335-341.
-
(2004)
Curr. Vasc. Pharmacol.
, vol.2
, pp. 335-341
-
-
Da Ros, R.1
Assaloni, R.2
Ceriello, A.3
-
70
-
-
28844505052
-
Increased sorbitol pathway activity generates oxidative stress in tissue sites for diabetic complications
-
Obrosova, I. G. Increased sorbitol pathway activity generates oxidative stress in tissue sites for diabetic complications. Antioxid. Redox. Signal., 2005, 7, 1543-1552.
-
(2005)
Antioxid. Redox. Signal.
, vol.7
, pp. 1543-1552
-
-
Obrosova, I.G.1
-
71
-
-
0037245335
-
Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation
-
Coppey, L. J.; Gellett, J. S.; Davidson, E. P.; Yorek, M. A. Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation. Free Radic. Res., 2003, 37, 33-40.
-
(2003)
Free Radic. Res.
, vol.37
, pp. 33-40
-
-
Coppey, L.J.1
Gellett, J.S.2
Davidson, E.P.3
Yorek, M.A.4
-
72
-
-
34547398616
-
A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice
-
Drel, V. R.; Pacher, P.; Vareniuk, I.; Pavlov, I.; Ilnytska, O.; Lyzogubov, V. V.; Tibrewala, J.; Groves, J. T.; Obrosova, I. G. A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice. Eur. J. Pharmacol., 2007, 569, 48-58.
-
(2007)
Eur. J. Pharmacol.
, vol.569
, pp. 48-58
-
-
Drel, V.R.1
Pacher, P.2
Vareniuk, I.3
Pavlov, I.4
Ilnytska, O.5
Lyzogubov, V.V.6
Tibrewala, J.7
Groves, J.T.8
Obrosova, I.G.9
-
73
-
-
42149132763
-
Evaluation of the peroxynitrite decomposition catalyst Fe (III) tetramesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes
-
Drel, V. R.; Pacher, P.; Vareniuk, I.; Pavlov, I. A.; Ilnytska, O.; Lyzogubov, V. V.; Bell, S. R.; Groves, J. T.; Obrosova, I. G. Evaluation of the peroxynitrite decomposition catalyst Fe (III) tetramesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes. Int. J. Mol. Med., 2007, 20, 783-792.
-
(2007)
Int. J. Mol. Med.
, vol.20
, pp. 783-792
-
-
Drel, V.R.1
Pacher, P.2
Vareniuk, I.3
Pavlov, I.A.4
Ilnytska, O.5
Lyzogubov, V.V.6
Bell, S.R.7
Groves, J.T.8
Obrosova, I.G.9
-
74
-
-
4744353904
-
Effects of the peroxynitrite decomposition catalyst, FeTMPyP, on function of corpus cavernosum from diabetic mice
-
Nangle, M. R.; Cotter, M. A.; Cameron, N. E. Effects of the peroxynitrite decomposition catalyst, FeTMPyP, on function of corpus cavernosum from diabetic mice. Eur. J. Pharmacol., 2004, 502, 143-148.
-
(2004)
Eur. J. Pharmacol.
, vol.502
, pp. 143-148
-
-
Nangle, M.R.1
Cotter, M.A.2
Cameron, N.E.3
-
75
-
-
37149032566
-
Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats
-
Obrosova, I. G.; Drel, V. R.; Oltman, C. L.; Mashtalir, N.; Tibrewala, J.; Groves, J. T.; Yorek, M. A. Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats. Am. J. Physiol. Endocrinol. Metab., 2007, 293, E1645-1655.
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.293
-
-
Obrosova, I.G.1
Drel, V.R.2
Oltman, C.L.3
Mashtalir, N.4
Tibrewala, J.5
Groves, J.T.6
Yorek, M.A.7
-
76
-
-
14644405532
-
Role for nitrosative stress in diabetic neuropathy: Evidence from studies with a peroxynitrite decomposition catalyst
-
Obrosova, I. G.; Mabley, J. G.; Zsengeller, Z.; Charniauskaya, T.; Abatan, O. I.; Groves, J. T.; Szabo, C. Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst. FASEB J., 2005, 19, 401-403.
-
(2005)
FASEB J.
, vol.19
, pp. 401-403
-
-
Obrosova, I.G.1
Mabley, J.G.2
Zsengeller, Z.3
Charniauskaya, T.4
Abatan, O.I.5
Groves, J.T.6
Szabo, C.7
-
77
-
-
34248560907
-
Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice
-
Vareniuk, I.; Pavlov, I. A.; Drel, V. R.; Lyzogubov, V. V.; Ilnytska, O.; Bell, S. R.; Tibrewala, J.; Groves, J. T.; Obrosova, I. G. Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice. Exp. Neurol., 2007, 205, 425-436.
-
(2007)
Exp. Neurol.
, vol.205
, pp. 425-436
-
-
Vareniuk, I.1
Pavlov, I.A.2
Drel, V.R.3
Lyzogubov, V.V.4
Ilnytska, O.5
Bell, S.R.6
Tibrewala, J.7
Groves, J.T.8
Obrosova, I.G.9
-
78
-
-
61849181013
-
Nitrosylated proteins in monocytes as a new marker of oxidative-nitrosative stress in diabetic subjects with macroangiopathy
-
Julius, U.; Drel, V. R.; Grassler, J.; Obrosova, I. G. Nitrosylated proteins in monocytes as a new marker of oxidative-nitrosative stress in diabetic subjects with macroangiopathy. Exp. Clin. Endocrinol. Diabetes, 2009, 117, 72-77.
-
(2009)
Exp. Clin. Endocrinol. Diabetes
, vol.117
, pp. 72-77
-
-
Julius, U.1
Drel, V.R.2
Grassler, J.3
Obrosova, I.G.4
-
79
-
-
53549112454
-
Inducible nitric oxide synthase gene deficiency counteracts multiple manifestations of peripheral neuropathy in a streptozotocin-induced mouse model of diabetes
-
Vareniuk, I.; Pavlov, I. A.; Obrosova, I. G. Inducible nitric oxide synthase gene deficiency counteracts multiple manifestations of peripheral neuropathy in a streptozotocin-induced mouse model of diabetes. Diabetologia, 2008, 51, 2126-2133.
-
(2008)
Diabetologia
, vol.51
, pp. 2126-2133
-
-
Vareniuk, I.1
Pavlov, I.A.2
Obrosova, I.G.3
-
80
-
-
33748292845
-
Poly (ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy
-
Ilnytska, O.; Lyzogubov, V. V.; Stevens, M. J.; Drel, V. R.; Mashtalir, N.; Pacher, P.; Yorek, M. A.; Obrosova, I. G. Poly (ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy. Diabetes, 2006, 55, 1686-1694.
-
(2006)
Diabetes
, vol.55
, pp. 1686-1694
-
-
Ilnytska, O.1
Lyzogubov, V.V.2
Stevens, M.J.3
Drel, V.R.4
Mashtalir, N.5
Pacher, P.6
Yorek, M.A.7
Obrosova, I.G.8
-
81
-
-
1442325591
-
Role of poly (ADP-ribose) polymerase activation in diabetic neuropathy
-
Obrosova, I. G.; Li, F.; Abatan, O. I.; Forsell, M. A.; Komjati, K.; Pacher, P.; Szabo, C.; Stevens, M. J. Role of poly (ADP-ribose) polymerase activation in diabetic neuropathy. Diabetes, 2004, 53, 711-720.
-
(2004)
Diabetes
, vol.53
, pp. 711-720
-
-
Obrosova, I.G.1
Li, F.2
Abatan, O.I.3
Forsell, M.A.4
Komjati, K.5
Pacher, P.6
Szabo, C.7
Stevens, M.J.8
-
82
-
-
0034078563
-
Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy
-
Thuraisingham, R. C.; Nott, C. A.; Dodd, S. M.; Yaqoob, M. M. Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy. Kidney Int., 2000, 57, 1968-1972.
-
(2000)
Kidney Int.
, vol.57
, pp. 1968-1972
-
-
Thuraisingham, R.C.1
Nott, C.A.2
Dodd, S.M.3
Yaqoob, M.M.4
-
83
-
-
0242352418
-
Increased nitric oxide levels as an early sign of premature aging in diabetes
-
Stadler, K.; Jenei, V.; von Bolcshazy, G.; Somogyi, A.; Jakus, J. Increased nitric oxide levels as an early sign of premature aging in diabetes. Free Radic. Biol. Med., 2003, 35, 1240-1251.
-
(2003)
Free Radic. Biol. Med.
, vol.35
, pp. 1240-1251
-
-
Stadler, K.1
Jenei, V.2
Von Bolcshazy, G.3
Somogyi, A.4
Jakus, J.5
-
84
-
-
18844395611
-
The pathogenesis of diabetic complications: The role of DNA injury and poly (ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity
-
Kiss, L.; Szabo, C. The pathogenesis of diabetic complications: the role of DNA injury and poly (ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity. Mem. Inst. Oswaldo Cruz, 2005, 100 (Suppl 1), 29-37.
-
(2005)
Mem. Inst. Oswaldo Cruz
, vol.100
, Issue.1 SUPPL.
, pp. 29-37
-
-
Kiss, L.1
Szabo, C.2
-
85
-
-
0041703027
-
Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly (ADP-ribose) polymerase activation
-
Minchenko, A. G.; Stevens, M. J.; White, L.; Abatan, O. I.; Komjati, K.; Pacher, P.; Szabo, C.; Obrosova, I. G. Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly (ADP-ribose) polymerase activation. FASEB J., 2003, 17, 1514-1516.
-
(2003)
FASEB J.
, vol.17
, pp. 1514-1516
-
-
Minchenko, A.G.1
Stevens, M.J.2
White, L.3
Abatan, O.I.4
Komjati, K.5
Pacher, P.6
Szabo, C.7
Obrosova, I.G.8
-
86
-
-
72149107087
-
Peroxynitrite plays a key role in glomerular lesions in diabetic rats
-
Xiao, H.; Li, Y.; Qi, J.; Wang, H.; Liu, K. Peroxynitrite plays a key role in glomerular lesions in diabetic rats. J. Nephrol., 2009, 22, 800-808.
-
(2009)
J. Nephrol.
, vol.22
, pp. 800-808
-
-
Xiao, H.1
Li, Y.2
Qi, J.3
Wang, H.4
Liu, K.5
-
87
-
-
77349127576
-
Peroxynitrite mediates glomerular lesion of diabetic rat via JAK/STAT signaling pathway
-
Wang, H.; Li, Y.; Liu, H.; Liu, S.; Liu, Q.; Wang, X. M.; Shi, Y.; Duan, H. Peroxynitrite mediates glomerular lesion of diabetic rat via JAK/STAT signaling pathway. J. Endocrinol. Invest., 2009, 32, 844-851.
-
(2009)
J. Endocrinol. Invest.
, vol.32
, pp. 844-851
-
-
Wang, H.1
Li, Y.2
Liu, H.3
Liu, S.4
Liu, Q.5
Wang, X.M.6
Shi, Y.7
Duan, H.8
-
88
-
-
12144279066
-
Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly (ADP-ribose) polymerase activation in tissue sites for diabetes complications
-
Obrosova, I. G.; Pacher, P.; Szabo, C.; Zsengeller, Z.; Hirooka, H.; Stevens, M. J.; Yorek, M. A. Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly (ADP-ribose) polymerase activation in tissue sites for diabetes complications. Diabetes, 2005, 54, 234-242.
-
(2005)
Diabetes
, vol.54
, pp. 234-242
-
-
Obrosova, I.G.1
Pacher, P.2
Szabo, C.3
Zsengeller, Z.4
Hirooka, H.5
Stevens, M.J.6
Yorek, M.A.7
-
89
-
-
33646068113
-
Aldose reductase inhibition counteracts nitrosative stress and poly (ADP-ribose) polymerase activation in diabetic rat kidney and high-glucoseexposed human mesangial cells
-
Drel, V. R.; Pacher, P.; Stevens, M. J.; Obrosova, I. G. Aldose reductase inhibition counteracts nitrosative stress and poly (ADP-ribose) polymerase activation in diabetic rat kidney and high-glucoseexposed human mesangial cells. Free Radic. Biol. Med., 2006, 40, 1454-1465.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 1454-1465
-
-
Drel, V.R.1
Pacher, P.2
Stevens, M.J.3
Obrosova, I.G.4
-
90
-
-
0036334679
-
Time course of NADH oxidase, inducible nitric oxide synthase and peroxynitrite in diabetic retinopathy in the BBZ/WOR rat
-
Ellis, E. A.; Guberski, D. L.; Hutson, B.; Grant, M. B. Time course of NADH oxidase, inducible nitric oxide synthase and peroxynitrite in diabetic retinopathy in the BBZ/WOR rat. Nitric Oxide, 2002, 6, 295-304.
-
(2002)
Nitric Oxide
, vol.6
, pp. 295-304
-
-
Ellis, E.A.1
Guberski, D.L.2
Hutson, B.3
Grant, M.B.4
-
91
-
-
34547858127
-
Metabolic memory phenomenon and accumulation of peroxynitrite in retinal capillaries
-
Kowluru, R. A.; Kanwar, M.; Kennedy, A. Metabolic memory phenomenon and accumulation of peroxynitrite in retinal capillaries. Exp. Diabetes Res., 2007, 2007, 21976.
-
(2007)
Exp. Diabetes Res.
, vol.2007
, pp. 21976
-
-
Kowluru, R.A.1
Kanwar, M.2
Kennedy, A.3
-
92
-
-
0037562523
-
High glucose-induced tyrosine nitration in endothelial cells: Role of eNOS uncoupling and aldose reductase activation
-
El-Remessy, A. B.; Abou-Mohamed, G.; Caldwell, R. W.; Caldwell, R. B. High glucose-induced tyrosine nitration in endothelial cells: role of eNOS uncoupling and aldose reductase activation. Invest. Ophthalmol. Vis. Sci., 2003, 44, 3135-3143.
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 3135-3143
-
-
El-Remessy, A.B.1
Abou-Mohamed, G.2
Caldwell, R.W.3
Caldwell, R.B.4
-
93
-
-
0033373370
-
Significance of nitric oxide and peroxynitrite in permeability changes of the retinal microvascular endothelial cell monolayer induced by vascular endothelial growth factor
-
Marumo, T.; Noll, T.; Schini-Kerth, V. B.; Harley, E. A.; Duhault, J.; Piper, H. M.; Busse, R. Significance of nitric oxide and peroxynitrite in permeability changes of the retinal microvascular endothelial cell monolayer induced by vascular endothelial growth factor. J. Vasc. Res., 1999, 36, 510-515.
-
(1999)
J. Vasc. Res.
, vol.36
, pp. 510-515
-
-
Marumo, T.1
Noll, T.2
Schini-Kerth, V.B.3
Harley, E.A.4
Duhault, J.5
Piper, H.M.6
Busse, R.7
-
94
-
-
0033778872
-
Lipid peroxidation and peroxynitrite in retinal ischemia-reperfusion injury
-
Shibuki, H.; Katai, N.; Yodoi, J.; Uchida, K.; Yoshimura, N. Lipid peroxidation and peroxynitrite in retinal ischemia-reperfusion injury. Invest. Ophthalmol. Vis. Sci., 2000, 41, 3607-3614.
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 3607-3614
-
-
Shibuki, H.1
Katai, N.2
Yodoi, J.3
Uchida, K.4
Yoshimura, N.5
-
95
-
-
33748516742
-
Early diabetes-induced biochemical changes in the retina: Comparison of rat and mouse models
-
Obrosova, I. G.; Drel, V. R.; Kumagai, A. K.; Szabo, C.; Pacher, P.; Stevens, M. J. Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models. Diabetologia, 2006, 49, 2525-2533.
-
(2006)
Diabetologia
, vol.49
, pp. 2525-2533
-
-
Obrosova, I.G.1
Drel, V.R.2
Kumagai, A.K.3
Szabo, C.4
Pacher, P.5
Stevens, M.J.6
-
96
-
-
0036319333
-
Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine
-
Du, Y.; Smith, M. A.; Miller, C. M.; Kern, T. S. Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine. J. Neurochem., 2002, 80, 771-779.
-
(2002)
J. Neurochem.
, vol.80
, pp. 771-779
-
-
Du, Y.1
Smith, M.A.2
Miller, C.M.3
Kern, T.S.4
-
97
-
-
6344293916
-
Peroxynitrite decomposition catalyst, FP15, and poly (ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats
-
Sugawara, R.; Hikichi, T.; Kitaya, N.; Mori, F.; Nagaoka, T.; Yoshida, A.; Szabo, C. Peroxynitrite decomposition catalyst, FP15, and poly (ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats. Curr. Eye. Res., 2004, 29, 11-16.
-
(2004)
Curr. Eye. Res.
, vol.29
, pp. 11-16
-
-
Sugawara, R.1
Hikichi, T.2
Kitaya, N.3
Mori, F.4
Nagaoka, T.5
Yoshida, A.6
Szabo, C.7
-
98
-
-
12144254266
-
Poly (ADP-ribose) polymerase inhibitors counteract diabetes-and hypoxiainduced retinal vascular endothelial growth factor overexpression
-
Obrosova, I. G.; Minchenko, A. G.; Frank, R. N.; Seigel, G. M.; Zsengeller, Z.; Pacher, P.; Stevens, M. J.; Szabo, C. Poly (ADP-ribose) polymerase inhibitors counteract diabetes-and hypoxiainduced retinal vascular endothelial growth factor overexpression. Int. J. Mol. Med., 2004, 14, 55-64.
-
(2004)
Int. J. Mol. Med.
, vol.14
, pp. 55-64
-
-
Obrosova, I.G.1
Minchenko, A.G.2
Frank, R.N.3
Seigel, G.M.4
Zsengeller, Z.5
Pacher, P.6
Stevens, M.J.7
Szabo, C.8
-
99
-
-
0036230482
-
Acute hyperglycemia induces nitrotyrosine formation and apoptosis in perfused heart from rat
-
Ceriello, A.; Quagliaro, L.; D'Amico, M.; Di Filippo, C.; Marfella, R.; Nappo, F.; Berrino, L.; Rossi, F.; Giugliano, D. Acute hyperglycemia induces nitrotyrosine formation and apoptosis in perfused heart from rat. Diabetes., 2002, 51, 1076-1082.
-
(2002)
Diabetes.
, vol.51
, pp. 1076-1082
-
-
Ceriello, A.1
Quagliaro, L.2
D'Amico, M.3
Di Filippo, C.4
Marfella, R.5
Nappo, F.6
Berrino, L.7
Rossi, F.8
Giugliano, D.9
-
100
-
-
28044432087
-
Role of nitric oxide in diabetic complications
-
Cohen, R. A. Role of nitric oxide in diabetic complications. Am. J. Ther., 2005, 12, 499-502.
-
(2005)
Am. J. Ther.
, vol.12
, pp. 499-502
-
-
Cohen, R.A.1
-
101
-
-
0034623856
-
Myocardial cell death in human diabetes
-
Frustaci, A.; Kajstura, J.; Chimenti, C.; Jakoniuk, I.; Leri, A.; Maseri, A.; Nadal-Ginard, B.; Anversa, P. Myocardial cell death in human diabetes. Circ. Res., 2000, 87, 1123-1132.
-
(2000)
Circ. Res.
, vol.87
, pp. 1123-1132
-
-
Frustaci, A.1
Kajstura, J.2
Chimenti, C.3
Jakoniuk, I.4
Leri, A.5
Maseri, A.6
Nadal-Ginard, B.7
Anversa, P.8
-
102
-
-
19544392527
-
Nitrosative stress and pharmacological modulation of heart failure
-
Pacher, P.; Schulz, R.; Liaudet, L.; Szabo, C. Nitrosative stress and pharmacological modulation of heart failure. Trends. Pharmacol. Sci., 2005, 26, 302-310.
-
(2005)
Trends. Pharmacol. Sci.
, vol.26
, pp. 302-310
-
-
Pacher, P.1
Schulz, R.2
Liaudet, L.3
Szabo, C.4
-
103
-
-
4444236143
-
Peroxynitrite and vascular endothelial dysfunction in diabetes mellitus
-
Zou, M. H.; Cohen, R.; Ullrich, V. Peroxynitrite and vascular endothelial dysfunction in diabetes mellitus. Endothelium, 2004, 11, 89-97.
-
(2004)
Endothelium
, vol.11
, pp. 89-97
-
-
Zou, M.H.1
Cohen, R.2
Ullrich, V.3
-
104
-
-
0036098197
-
High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H (2) receptormediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells
-
Zou, M. H.; Shi, C.; Cohen, R. A. High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H (2) receptormediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells. Diabetes, 2002, 51, 198-203.
-
(2002)
Diabetes
, vol.51
, pp. 198-203
-
-
Zou, M.H.1
Shi, C.2
Cohen, R.A.3
-
105
-
-
33747598024
-
Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo
-
Levrand, S.; Vannay-Bouchiche, C.; Pesse, B.; Pacher, P.; Feihl, F.; Waeber, B.; Liaudet, L. Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo. Free Radic. Biol. Med., 2006, 41, 886-895.
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 886-895
-
-
Levrand, S.1
Vannay-Bouchiche, C.2
Pesse, B.3
Pacher, P.4
Feihl, F.5
Waeber, B.6
Liaudet, L.7
-
106
-
-
0036199685
-
Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
-
Zou, M. H.; Shi, C.; Cohen, R. A. Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J. Clin. Invest., 2002, 109, 817-826.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 817-826
-
-
Zou, M.H.1
Shi, C.2
Cohen, R.A.3
-
107
-
-
33645806282
-
S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells
-
Clavreul, N.; Adachi, T.; Pimental, D. R.; Ido, Y.; Schoneich, C.; Cohen, R. A. S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells. FASEB J., 2006, 20, 518-520.
-
(2006)
FASEB J.
, vol.20
, pp. 518-520
-
-
Clavreul, N.1
Adachi, T.2
Pimental, D.R.3
Ido, Y.4
Schoneich, C.5
Cohen, R.A.6
-
108
-
-
33750217204
-
S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein
-
Clavreul, N.; Bachschmid, M. M.; Hou, X.; Shi, C.; Idrizovic, A.; Ido, Y.; Pimentel, D.; Cohen, R. A. S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein. Arterioscler. Thromb. Vasc. Biol., 2006, 26, 2454-2461.
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 2454-2461
-
-
Clavreul, N.1
Bachschmid, M.M.2
Hou, X.3
Shi, C.4
Idrizovic, A.5
Ido, Y.6
Pimentel, D.7
Cohen, R.A.8
-
109
-
-
0036215470
-
Endothelial dysfunction in aging animals: The role of poly (ADP-ribose) polymerase activation
-
Pacher, P.; Mabley, J. G.; Soriano, F. G.; Liaudet, L.; Komjati, K.; Szabo, C. Endothelial dysfunction in aging animals: the role of poly (ADP-ribose) polymerase activation. Br. J. Pharmacol., 2002, 135, 1347-1350.
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 1347-1350
-
-
Pacher, P.1
Mabley, J.G.2
Soriano, F.G.3
Liaudet, L.4
Komjati, K.5
Szabo, C.6
-
110
-
-
0036064154
-
The role of poly (ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes
-
Pacher, P.; Liaudet, L.; Soriano, F. G.; Mabley, J. G.; Szabo, E.; Szabo, C. The role of poly (ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes. Diabetes, 2002, 51, 514-521.
-
(2002)
Diabetes
, vol.51
, pp. 514-521
-
-
Pacher, P.1
Liaudet, L.2
Soriano, F.G.3
Mabley, J.G.4
Szabo, E.5
Szabo, C.6
-
111
-
-
0037137287
-
Poly (ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity
-
Szabo, C.; Zanchi, A.; Komjati, K.; Pacher, P.; Krolewski, A. S.; Quist, W. C.; Lo Gerfo, F. W.; Horton, E. S.; Veves, A. Poly (ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity. Circulation, 2002, 106, 2680-2686.
-
(2002)
Circulation
, vol.106
, pp. 2680-2686
-
-
Szabo, C.1
Zanchi, A.2
Komjati, K.3
Pacher, P.4
Krolewski, A.S.5
Quist, W.C.6
Lo Gerfo, F.W.7
Horton, E.S.8
Veves, A.9
-
112
-
-
0037019589
-
Pharmacologic inhibition of poly (adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure
-
Pacher, P.; Liaudet, L.; Mabley, J.; Komjati, K.; Szabo, C. Pharmacologic inhibition of poly (adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure. J. Am. Coll. Cardiol., 2002, 40, 1006-1016.
-
(2002)
J. Am. Coll. Cardiol.
, vol.40
, pp. 1006-1016
-
-
Pacher, P.1
Liaudet, L.2
Mabley, J.3
Komjati, K.4
Szabo, C.5
-
113
-
-
0036615996
-
Activation of poly (ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging
-
Pacher, P.; Mabley, J. G.; Soriano, F. G.; Liaudet, L.; Szabo, C. Activation of poly (ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging. Int. J. Mol. Med., 2002, 9, 659-664.
-
(2002)
Int. J. Mol. Med.
, vol.9
, pp. 659-664
-
-
Pacher, P.1
Mabley, J.G.2
Soriano, F.G.3
Liaudet, L.4
Szabo, C.5
-
114
-
-
28844462418
-
Role of poly (ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: Endothelial dysfunction, as a common underlying theme
-
Pacher, P.; Szabo, C. Role of poly (ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme. Antioxid. Redox. Signal., 2005, 7, 1568-1580.
-
(2005)
Antioxid. Redox. Signal.
, vol.7
, pp. 1568-1580
-
-
Pacher, P.1
Szabo, C.2
-
115
-
-
0034743753
-
IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress
-
Kajstura, J.; Fiordaliso, F.; Andreoli, A. M.; Li, B.; Chimenti, S.; Medow, M. S.; Limana, F.; Nadal-Ginard, B.; Leri, A.; Anversa, P. IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress. Diabetes, 2001, 50, 1414-1424.
-
(2001)
Diabetes
, vol.50
, pp. 1414-1424
-
-
Kajstura, J.1
Fiordaliso, F.2
Andreoli, A.M.3
Li, B.4
Chimenti, S.5
Medow, M.S.6
Limana, F.7
Nadal-Ginard, B.8
Leri, A.9
Anversa, P.10
-
116
-
-
16344393699
-
Beneficial effects of aminoguanidine on the cardiovascular system of diabetic rats
-
Stadler, K.; Jenei, V.; Somogyi, A.; Jakus, J. Beneficial effects of aminoguanidine on the cardiovascular system of diabetic rats. Diabetes Metab. Res. Rev., 2005, 21, 189-196.
-
(2005)
Diabetes Metab. Res. Rev.
, vol.21
, pp. 189-196
-
-
Stadler, K.1
Jenei, V.2
Somogyi, A.3
Jakus, J.4
-
117
-
-
0142125202
-
Role of nitric oxide, tetrahydrobiopterin and peroxynitrite in glucose toxicity-associated contractile dysfunction in ventricular myocytes
-
Esberg, L. B.; Ren, J. Role of nitric oxide, tetrahydrobiopterin and peroxynitrite in glucose toxicity-associated contractile dysfunction in ventricular myocytes. Diabetologia, 2003, 46, 1419-1427.
-
(2003)
Diabetologia
, vol.46
, pp. 1419-1427
-
-
Esberg, L.B.1
Ren, J.2
-
118
-
-
6344256347
-
A new, potent poly (ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging
-
Pacher, P.; Vaslin, A.; Benko, R.; Mabley, J. G.; Liaudet, L.; Hasko, G.; Marton, A.; Batkai, S.; Kollai, M.; Szabo, C. A new, potent poly (ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging. J. Pharmacol. Exp. Ther., 2004, 311, 485-491.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.311
, pp. 485-491
-
-
Pacher, P.1
Vaslin, A.2
Benko, R.3
Mabley, J.G.4
Liaudet, L.5
Hasko, G.6
Marton, A.7
Batkai, S.8
Kollai, M.9
Szabo, C.10
-
119
-
-
0035851210
-
Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly (ADP-ribose) polymerase
-
Soriano, F. G.; Pacher, P.; Mabley, J.; Liaudet, L.; Szabo, C. Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly (ADP-ribose) polymerase. Circ. Res., 2001, 89, 684-691.
-
(2001)
Circ. Res.
, vol.89
, pp. 684-691
-
-
Soriano, F.G.1
Pacher, P.2
Mabley, J.3
Liaudet, L.4
Szabo, C.5
-
120
-
-
46649090918
-
Protein tyrosine nitration-functional alteration or just a biomarker?
-
Souza, J. M.; Peluffo, G.; Radi, R. Protein tyrosine nitration-functional alteration or just a biomarker? Free Radic. Biol. Med., 2008, 45, 357-366.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 357-366
-
-
Souza, J.M.1
Peluffo, G.2
Radi, R.3
-
121
-
-
0035853685
-
Reaction of peroxynitrite with Mnsuperoxide dismutase. Role of the metal center in decomposition kinetics and nitration
-
Quijano, C.; Hernandez-Saavedra, D.; Castro, L.; McCord, J. M.; Freeman, B. A.; Radi, R. Reaction of peroxynitrite with Mnsuperoxide dismutase. Role of the metal center in decomposition kinetics and nitration. J. Biol. Chem., 2001, 276, 11631-11638.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11631-11638
-
-
Quijano, C.1
Hernandez-Saavedra, D.2
Castro, L.3
McCord, J.M.4
Freeman, B.A.5
Radi, R.6
-
122
-
-
0029862502
-
Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts
-
MacMillan-Crow, L. A.; Crow, J. P.; Kerby, J. D.; Beckman, J. S.; Thompson, J. A. Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts. Proc. Natl. Acad. Sci. U. S. A., 1996, 93, 11853-11858.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 11853-11858
-
-
MacMillan-Crow, L.A.1
Crow, J.P.2
Kerby, J.D.3
Beckman, J.S.4
Thompson, J.A.5
-
123
-
-
9144229591
-
Functional consequences of alpha-synuclein tyrosine nitration: Diminished binding to lipid vesicles and increased fibril formation
-
Hodara, R.; Norris, E. H.; Giasson, B. I.; Mishizen-Eberz, A. J.; Lynch, D. R.; Lee, V. M.; Ischiropoulos, H. Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. J. Biol. Chem., 2004, 279, 47746-47753.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47746-47753
-
-
Hodara, R.1
Norris, E.H.2
Giasson, B.I.3
Mishizen-Eberz, A.J.4
Lynch, D.R.5
Lee, V.M.6
Ischiropoulos, H.7
-
124
-
-
10744226883
-
Pro-thrombotic state induced by post-translational modification of fibrinogen by reactive nitrogen species
-
Vadseth, C.; Souza, J. M.; Thomson, L.; Seagraves, A.; Nagaswami, C.; Scheiner, T.; Torbet, J.; Vilaire, G.; Bennett, J. S.; Murciano, J. C.; Muzykantov, V.; Penn, M. S.; Hazen, S. L.; Weisel, J. W.; Ischiropoulos, H. Pro-thrombotic state induced by post-translational modification of fibrinogen by reactive nitrogen species. J. Biol. Chem., 2004, 279, 8820-8826.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 8820-8826
-
-
Vadseth, C.1
Souza, J.M.2
Thomson, L.3
Seagraves, A.4
Nagaswami, C.5
Scheiner, T.6
Torbet, J.7
Vilaire, G.8
Bennett, J.S.9
Murciano, J.C.10
Muzykantov, V.11
Penn, M.S.12
Hazen, S.L.13
Weisel, J.W.14
Ischiropoulos, H.15
-
125
-
-
0034647729
-
Cytochrome c nitration by peroxynitrite
-
Cassina, A. M.; Hodara, R.; Souza, J. M.; Thomson, L.; Castro, L.; Ischiropoulos, H.; Freeman, B. A.; Radi, R. Cytochrome c nitration by peroxynitrite. J. Biol. Chem., 2000, 275, 21409-21415.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21409-21415
-
-
Cassina, A.M.1
Hodara, R.2
Souza, J.M.3
Thomson, L.4
Castro, L.5
Ischiropoulos, H.6
Freeman, B.A.7
Radi, R.8
-
126
-
-
0034073045
-
Plasma proteins modified by tyrosine nitration in acute respiratory distress syndrome
-
Gole, M. D.; Souza, J. M.; Choi, I.; Hertkorn, C.; Malcolm, S.; Foust, R. F., 3rd; Finkel, B.; Lanken, P. N.; Ischiropoulos, H. Plasma proteins modified by tyrosine nitration in acute respiratory distress syndrome. Am. J. Physiol. Lung. Cell. Mol. Physiol., 2000, 278, L961-967.
-
(2000)
Am. J. Physiol. Lung. Cell. Mol. Physiol.
, vol.278
-
-
Gole, M.D.1
Souza, J.M.2
Choi, I.3
Hertkorn, C.4
Malcolm, S.5
Foust III, R.F.6
Finkel, B.7
Lanken, P.N.8
Ischiropoulos, H.9
-
127
-
-
46749118458
-
Role of the peroxynitrite-poly (ADP-ribose) polymerase pathway in human disease
-
Pacher, P.; Szabo, C. Role of the peroxynitrite-poly (ADP-ribose) polymerase pathway in human disease. Am. J. Pathol., 2008, 173, 2-13.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 2-13
-
-
Pacher, P.1
Szabo, C.2
-
128
-
-
64049094318
-
Poly (ADP-ribose) polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats
-
Drel, V. R.; Xu, W.; Zhang, J.; Kador, P. F.; Ali, T. K.; Shin, J.; Julius, U.; Slusher, B.; El-Remessy, A. B.; Obrosova, I. G. Poly (ADP-ribose) polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats. Invest. Ophthalmol. Vis. Sci., 2009, 50, 1778-1790.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 1778-1790
-
-
Drel, V.R.1
Xu, W.2
Zhang, J.3
Kador, P.F.4
Ali, T.K.5
Shin, J.6
Julius, U.7
Slusher, B.8
El-Remessy, A.B.9
Obrosova, I.G.10
-
129
-
-
70349261110
-
The aldose reductase inhibitor fidarestat suppresses ischemia- reperfusioninduced inflammatory response in rat retina
-
Agardh, C. D.; Agardh, E.; Obrosova, I. G.; Smith, M. L. The aldose reductase inhibitor fidarestat suppresses ischemia-reperfusioninduced inflammatory response in rat retina. Pharmacology, 2009, 84, 257-263.
-
(2009)
Pharmacology
, vol.84
, pp. 257-263
-
-
Agardh, C.D.1
Agardh, E.2
Obrosova, I.G.3
Smith, M.L.4
-
130
-
-
71949105951
-
Poly (Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy
-
Drel, V. R.; Xu, W.; Zhang, J.; Pavlov, I. A.; Shevalye, H.; Slusher, B.; Obrosova, I. G. Poly (Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy. Endocrinology, 2009, 150, 5273-5283.
-
(2009)
Endocrinology
, vol.150
, pp. 5273-5283
-
-
Drel, V.R.1
Xu, W.2
Zhang, J.3
Pavlov, I.A.4
Shevalye, H.5
Slusher, B.6
Obrosova, I.G.7
-
131
-
-
77449124908
-
Poly (ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model
-
Shevalye, H.; Stavniichuk, R.; Xu, W.; Zhang, J.; Lupachyk, S.; Maksimchyk, Y.; Drel, V. R.; Floyd, E. Z.; Slusher, B.; Obrosova, I. G. Poly (ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model. Biochem. Pharmacol., 2010, 79, 1007-1014.
-
(2010)
Biochem. Pharmacol.
, vol.79
, pp. 1007-1014
-
-
Shevalye, H.1
Stavniichuk, R.2
Xu, W.3
Zhang, J.4
Lupachyk, S.5
Maksimchyk, Y.6
Drel, V.R.7
Floyd, E.Z.8
Slusher, B.9
Obrosova, I.G.10
-
132
-
-
39849088155
-
PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy
-
Obrosova, I. G.; Xu, W.; Lyzogubov, V. V.; Ilnytska, O.; Mashtalir, N.; Vareniuk, I.; Pavlov, I. A.; Zhang, J.; Slusher, B.; Drel, V. R. PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy. Free Radic. Biol. Med., 2008, 44, 972-981.
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 972-981
-
-
Obrosova, I.G.1
Xu, W.2
Lyzogubov, V.V.3
Ilnytska, O.4
Mashtalir, N.5
Vareniuk, I.6
Pavlov, I.A.7
Zhang, J.8
Slusher, B.9
Drel, V.R.10
-
133
-
-
68449101576
-
Nitrative stress and poly (ADP-ribose) polymerase activation in healthy and gestational diabetic pregnancies
-
Horvath, E. M.; Magenheim, R.; Kugler, E.; Vacz, G.; Szigethy, A.; Levardi, F.; Kollai, M.; Szabo, C.; Lacza, Z. Nitrative stress and poly (ADP-ribose) polymerase activation in healthy and gestational diabetic pregnancies. Diabetologia, 2009, 52, 1935-1943.
-
(2009)
Diabetologia
, vol.52
, pp. 1935-1943
-
-
Horvath, E.M.1
Magenheim, R.2
Kugler, E.3
Vacz, G.4
Szigethy, A.5
Levardi, F.6
Kollai, M.7
Szabo, C.8
Lacza, Z.9
-
134
-
-
72949103912
-
Concurrent targeting of nitrosative stress-PARP pathway corrects functional, behavioral and biochemical deficits in experimental diabetic neuropathy
-
Negi, G.; Kumar, A.; Sharma, S. S. Concurrent targeting of nitrosative stress-PARP pathway corrects functional, behavioral and biochemical deficits in experimental diabetic neuropathy. Biochem. Biophys. Res. Commun., 2010, 391, 102-106.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 102-106
-
-
Negi, G.1
Kumar, A.2
Sharma, S.S.3
-
135
-
-
64149103180
-
Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction
-
Szabo, C. Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction. Br. J. Pharmacol., 2009, 156, 713-727.
-
(2009)
Br. J. Pharmacol.
, vol.156
, pp. 713-727
-
-
Szabo, C.1
-
136
-
-
33845523337
-
The leptin-deficient (ob/ob) mouse: A new animal model of peripheral neuropathy of type 2 diabetes and obesity
-
Drel, V. R.; Mashtalir, N.; Ilnytska, O.; Shin, J.; Li, F.; Lyzogubov, V. V.; Obrosova, I. G. The leptin-deficient (ob/ob) mouse: a new animal model of peripheral neuropathy of type 2 diabetes and obesity. Diabetes, 2006, 55, 3335-3343.
-
(2006)
Diabetes
, vol.55
, pp. 3335-3343
-
-
Drel, V.R.1
Mashtalir, N.2
Ilnytska, O.3
Shin, J.4
Li, F.5
Lyzogubov, V.V.6
Obrosova, I.G.7
-
137
-
-
34547399482
-
High-fat diet induced neuropathy of pre-diabetes and obesity: Effects of "healthy" diet and aldose reductase inhibition
-
Obrosova, I. G.; Ilnytska, O.; Lyzogubov, V. V.; Pavlov, I. A.; Mashtalir, N.; Nadler, J. L.; Drel, V. R. High-fat diet induced neuropathy of pre-diabetes and obesity: effects of "healthy" diet and aldose reductase inhibition. Diabetes, 2007, 56, 2598-2608.
-
(2007)
Diabetes
, vol.56
, pp. 2598-2608
-
-
Obrosova, I.G.1
Ilnytska, O.2
Lyzogubov, V.V.3
Pavlov, I.A.4
Mashtalir, N.5
Nadler, J.L.6
Drel, V.R.7
-
138
-
-
70349303776
-
Diabetic painful and insensate neuropathy: Pathogenesis and potential treatments
-
Obrosova, I. G. Diabetic painful and insensate neuropathy: pathogenesis and potential treatments. Neurotherapeutics, 2009, 6, 638-647.
-
(2009)
Neurotherapeutics
, vol.6
, pp. 638-647
-
-
Obrosova, I.G.1
-
139
-
-
53249085786
-
Amelioration of neurological and biochemical deficits by peroxynitrite decomposition catalysts in experimental diabetic neuropathy
-
Arora, M.; Kumar, A.; Kaundal, R. K.; Sharma, S. S. Amelioration of neurological and biochemical deficits by peroxynitrite decomposition catalysts in experimental diabetic neuropathy. Eur. J. Pharmacol., 2008, 596, 77-83.
-
(2008)
Eur. J. Pharmacol.
, vol.596
, pp. 77-83
-
-
Arora, M.1
Kumar, A.2
Kaundal, R.K.3
Sharma, S.S.4
-
140
-
-
63849118178
-
Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy
-
Zheng, L.; Kern, T. S. Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy. Front Biosci., 2009, 14, 3974-3987.
-
(2009)
Front Biosci.
, vol.14
, pp. 3974-3987
-
-
Zheng, L.1
Kern, T.S.2
-
141
-
-
73949127943
-
Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy
-
Abdelsaid, M. A.; Pillai, B. A.; Matragoon, S.; Prakash, R.; Al-Shabrawey, M.; El-Remessy, A. B. Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy. J. Pharmacol. Exp. Ther., 2010, 332, 125-134.
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, pp. 125-134
-
-
Abdelsaid, M.A.1
Pillai, B.A.2
Matragoon, S.3
Prakash, R.4
Al-Shabrawey, M.5
El-Remessy, A.B.6
-
142
-
-
67649415964
-
Peripheral neuropathy in mice with neuronal nitric oxide synthase gene deficiency
-
Vareniuk, I.; Pacher, P.; Pavlov, I. A.; Drel, V. R.; Obrosova, I. G. Peripheral neuropathy in mice with neuronal nitric oxide synthase gene deficiency. Int. J. Mol. Med., 2009, 23, 571-580.
-
(2009)
Int. J. Mol. Med.
, vol.23
, pp. 571-580
-
-
Vareniuk, I.1
Pacher, P.2
Pavlov, I.A.3
Drel, V.R.4
Obrosova, I.G.5
-
143
-
-
21844474541
-
Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy
-
Ii, M.; Nishimura, H.; Kusano, K. F.; Qin, G.; Yoon, Y. S.; Wecker, A.; Asahara, T.; Losordo, D. W. Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy. Circulation, 2005, 112, 93-102.
-
(2005)
Circulation
, vol.112
, pp. 93-102
-
-
Ii, M.1
Nishimura, H.2
Kusano, K.F.3
Qin, G.4
Yoon, Y.S.5
Wecker, A.6
Asahara, T.7
Losordo, D.W.8
-
144
-
-
42949117941
-
Analysis of NO-synthase expression and clinical risk factors in human diabetic nephropathy
-
Hohenstein, B.; Hugo, C. P.; Hausknecht, B.; Boehmer, K. P.; Riess, R. H.; Schmieder, R. E. Analysis of NO-synthase expression and clinical risk factors in human diabetic nephropathy. Nephrol. Dial. Transplant., 2008, 23, 1346-1354.
-
(2008)
Nephrol. Dial. Transplant.
, vol.23
, pp. 1346-1354
-
-
Hohenstein, B.1
Hugo, C.P.2
Hausknecht, B.3
Boehmer, K.P.4
Riess, R.H.5
Schmieder, R.E.6
-
145
-
-
54949144344
-
Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes
-
Stadler, K.; Bonini, M. G.; Dallas, S.; Jiang, J.; Radi, R.; Mason, R. P.; Kadiiska, M. B. Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes. Free Radic. Biol. Med., 2008, 45, 866-874.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 866-874
-
-
Stadler, K.1
Bonini, M.G.2
Dallas, S.3
Jiang, J.4
Radi, R.5
Mason, R.P.6
Kadiiska, M.B.7
-
146
-
-
0034770292
-
Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle
-
Perreault, M.; Marette, A. Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle. Nat. Med., 2001, 7, 1138-1143.
-
(2001)
Nat. Med.
, vol.7
, pp. 1138-1143
-
-
Perreault, M.1
Marette, A.2
-
147
-
-
50949133177
-
Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptorgamma agonism
-
Dallaire, P.; Bellmann, K.; Laplante, M.; Gelinas, S.; Centeno-Baez, C.; Penfornis, P.; Peyot, M. L.; Latour, M. G.; Lamontagne, J.; Trujillo, M. E.; Scherer, P. E.; Prentki, M.; Deshaies, Y.; Marette, A. Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptorgamma agonism. Diabetes, 2008, 57, 1999-2011.
-
(2008)
Diabetes
, vol.57
, pp. 1999-2011
-
-
Dallaire, P.1
Bellmann, K.2
Laplante, M.3
Gelinas, S.4
Centeno-Baez, C.5
Penfornis, P.6
Peyot, M.L.7
Latour, M.G.8
Lamontagne, J.9
Trujillo, M.E.10
Scherer, P.E.11
Prentki, M.12
Deshaies, Y.13
Marette, A.14
-
148
-
-
70350007177
-
Peroxynitrite mediates muscle insulin resistance in mice via nitration of IRbeta/IRS-1 and Akt
-
Zhou, J.; Huang, K. Peroxynitrite mediates muscle insulin resistance in mice via nitration of IRbeta/IRS-1 and Akt. Toxicol. Appl. Pharmacol., 2009, 241, 101-110.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.241
, pp. 101-110
-
-
Zhou, J.1
Huang, K.2
-
149
-
-
50049097616
-
Stimulation of peroxynitrite catalysis improves insulin sensitivity in high fat diet-fed mice
-
Duplain, H.; Sartori, C.; Dessen, P.; Jayet, P. Y.; Schwab, M.; Bloch, J.; Nicod, P.; Scherrer, U. Stimulation of peroxynitrite catalysis improves insulin sensitivity in high fat diet-fed mice. J. Physiol., 2008, 586, 4011-4016.
-
(2008)
J. Physiol.
, vol.586
, pp. 4011-4016
-
-
Duplain, H.1
Sartori, C.2
Dessen, P.3
Jayet, P.Y.4
Schwab, M.5
Bloch, J.6
Nicod, P.7
Scherrer, U.8
-
150
-
-
77951178397
-
INOS induction underlies lipidinduced hepatic insulin resistance in mice: Potential role of tyrosine nitration of insulin signaling proteins
-
Charbonneau, A.; Marette, A. iNOS induction underlies lipidinduced hepatic insulin resistance in mice: Potential role of tyrosine nitration of insulin signaling proteins. Diabetes, 2010, 59, 861-871.
-
(2010)
Diabetes
, vol.59
, pp. 861-871
-
-
Charbonneau, A.1
Marette, A.2
-
151
-
-
3042841983
-
Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1
-
Nomiyama, T.; Igarashi, Y.; Taka, H.; Mineki, R.; Uchida, T.; Ogihara, T.; Choi, J. B.; Uchino, H.; Tanaka, Y.; Maegawa, H.; Kashiwagi, A.; Murayama, K.; Kawamori, R.; Watada, H. Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1. Biochem. Biophys. Res. Commun., 2004, 320, 639-647.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 639-647
-
-
Nomiyama, T.1
Igarashi, Y.2
Taka, H.3
Mineki, R.4
Uchida, T.5
Ogihara, T.6
Choi, J.B.7
Uchino, H.8
Tanaka, Y.9
Maegawa, H.10
Kashiwagi, A.11
Murayama, K.12
Kawamori, R.13
Watada, H.14
-
152
-
-
15944378147
-
S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: A novel mechanism of insulin resistance
-
Carvalho-Filho, M. A.; Ueno, M.; Hirabara, S. M.; Seabra, A. B.; Carvalheira, J. B.; de Oliveira, M. G.; Velloso, L. A.; Curi, R.; Saad, M. J. S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes, 2005, 54, 959-967.
-
(2005)
Diabetes
, vol.54
, pp. 959-967
-
-
Carvalho-Filho, M.A.1
Ueno, M.2
Hirabara, S.M.3
Seabra, A.B.4
Carvalheira, J.B.5
De Oliveira, M.G.6
Velloso, L.A.7
Curi, R.8
Saad, M.J.9
-
153
-
-
33748470543
-
Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice
-
Carvalho-Filho, M. A.; Ueno, M.; Carvalheira, J. B.; Velloso, L. A.; Saad, M. J. Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice. Am. J. Physiol. Endocrinol. Metab., 2006, 291, E476-482.
-
(2006)
Am. J. Physiol. Endocrinol. Metab.
, vol.291
-
-
Carvalho-Filho, M.A.1
Ueno, M.2
Carvalheira, J.B.3
Velloso, L.A.4
Saad, M.J.5
-
154
-
-
0030002384
-
Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation
-
Gow, A. J.; Duran, D.; Malcolm, S.; Ischiropoulos, H. Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett., 1996, 385, 63-66.
-
(1996)
FEBS Lett.
, vol.385
, pp. 63-66
-
-
Gow, A.J.1
Duran, D.2
Malcolm, S.3
Ischiropoulos, H.4
-
155
-
-
0033559897
-
Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death
-
Brito, C.; Naviliat, M.; Tiscornia, A. C.; Vuillier, F.; Gualco, G.; Dighiero, G.; Radi, R.; Cayota, A. M. Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death. J. Immunol., 1999, 162, 3356-3366.
-
(1999)
J. Immunol.
, vol.162
, pp. 3356-3366
-
-
Brito, C.1
Naviliat, M.2
Tiscornia, A.C.3
Vuillier, F.4
Gualco, G.5
Dighiero, G.6
Radi, R.7
Cayota, A.M.8
-
156
-
-
0034657292
-
Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma
-
MacMillan-Crow, L. A.; Greendorfer, J. S.; Vickers, S. M.; Thompson, J. A. Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma. Arch. Biochem. Biophys., 2000, 377, 350-356.
-
(2000)
Arch. Biochem. Biophys.
, vol.377
, pp. 350-356
-
-
MacMillan-Crow, L.A.1
Greendorfer, J.S.2
Vickers, S.M.3
Thompson, J.A.4
-
157
-
-
52049125425
-
Tyrosine nitration, dimerization, and hydroxylation by peroxynitrite in membranes as studied by the hydrophobic probe N-t-BOC-l-tyrosine tert-butyl ester
-
Bartesaghi, S.; Peluffo, G.; Zhang, H.; Joseph, J.; Kalyanaraman, B.; Radi, R. Tyrosine nitration, dimerization, and hydroxylation by peroxynitrite in membranes as studied by the hydrophobic probe N-t-BOC-l-tyrosine tert-butyl ester. Methods Enzymol., 2008, 441, 217-236.
-
(2008)
Methods Enzymol.
, vol.441
, pp. 217-236
-
-
Bartesaghi, S.1
Peluffo, G.2
Zhang, H.3
Joseph, J.4
Kalyanaraman, B.5
Radi, R.6
-
158
-
-
77951216182
-
Lipid peroxyl radicals mediate tyrosine dimerization and nitration in membranes
-
Bartesaghi, S.; Wenzel, J.; Trujillo, M.; Lopez, M.; Joseph, J.; Kalyanaraman, B.; Radi, R. Lipid Peroxyl Radicals Mediate Tyrosine Dimerization and Nitration in Membranes. Chem. Res. Toxicol., 2010, 23, 821-835.
-
(2010)
Chem. Res. Toxicol.
, vol.23
, pp. 821-835
-
-
Bartesaghi, S.1
Wenzel, J.2
Trujillo, M.3
Lopez, M.4
Joseph, J.5
Kalyanaraman, B.6
Radi, R.7
|