Long term effect of curcumin in restoration of tumour suppressor p53 and phase-II antioxidant enzymes via activation of Nrf2 signalling and modulation of inflammation in prevention of cancer

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Das, Laxmidhar ^a   Vinayak, Manjula ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CURCUMIN; CYCLOOXYGENASE 2; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA; ANTINEOPLASTIC AGENT; ANTIOXIDANT; AUTACOID; NFE2L2 PROTEIN, MOUSE; NOS2 PROTEIN, MOUSE; NQO1 PROTEIN, MOUSE; PROTEIN BINDING; PTGS2 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER PREVENTION; CONSENSUS SEQUENCE; CONTROLLED STUDY; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME REGULATION; INFLAMMATION; LIVER METASTASIS; LIVER PARENCHYMA; MALE; MOUSE; NONHUMAN; OXIDATION; OXIDATION REDUCTION STATE; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; T CELL LYMPHOMA; TUMOR MICROENVIRONMENT; UPREGULATION; AKR MOUSE; ANIMAL; DRUG EFFECTS; GENETICS; LIVER; LYMPHOMA, T-CELL; METABOLISM;

MUS;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; CONSENSUS SEQUENCE; CURCUMIN; CYCLOOXYGENASE 2; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; INFLAMMATION MEDIATORS; LIVER; LYMPHOMA, T-CELL; MALE; MICE; MICE, INBRED AKR; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN BINDING; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84928911735     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124000     Document Type: Article

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