-
2
-
-
0037422592
-
Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises. Part I: Aging arteries: A set up" for vascular disease
-
Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. Part I: aging arteries: a "set up" for vascular disease. Circulation. 2003;107:139-146.
-
(2003)
Circulation
, vol.107
, pp. 139-146
-
-
Lakatta, E.G.1
Levy, D.2
-
3
-
-
1942438660
-
Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing
-
Eskurza I, Monahan KD, Robinson JA, Seals DR. Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol (Lond). 2004;556(pt 1):315-324.
-
(2004)
J Physiol (Lond
, vol.556
, Issue.PART 1
, pp. 315-324
-
-
Eskurza, I.1
Monahan, K.D.2
Robinson, J.A.3
Seals, D.R.4
-
4
-
-
0028134614
-
Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction
-
Celermajer DS, Sorensen KE, Bull C, Robinson J, Deanfield JE. Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction. J Am Coll Cardiol. 1994;24:1468-1474.
-
(1994)
J Am Coll Cardiol
, vol.24
, pp. 1468-1474
-
-
Celermajer, D.S.1
Sorensen, K.E.2
Bull, C.3
Robinson, J.4
Deanfield, J.E.5
-
5
-
-
27444437661
-
Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-α activators
-
Han SH, Quon MJ, Koh KK. Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-α activators. Hypertension. 2005;46:1086-1092.
-
(2005)
Hypertension
, vol.46
, pp. 1086-1092
-
-
Han, S.H.1
Quon, M.J.2
Koh, K.K.3
-
6
-
-
34248662090
-
Fenofibrate improves age-related endothelial dysfunction in rat resistance arteries
-
Alvarez de Sotomayor M, Mingorance C, Andriantsitohaina R. Fenofibrate improves age-related endothelial dysfunction in rat resistance arteries. Atherosclerosis. 2007;193:112-120.
-
(2007)
Atherosclerosis
, vol.193
, pp. 112-120
-
-
Alvarez De Sotomayor, M.1
Mingorance, C.2
Andriantsitohaina, R.3
-
7
-
-
0035570723
-
Age-related reduction of NO availability and oxidative stress in humans
-
Taddei S, Virdis A, Ghiadoni L, Salvetti G, Bernini G, Magagna A, Salvetti A. Age-related reduction of NO availability and oxidative stress in humans. Hypertension. 2001;38:274-279.
-
(2001)
Hypertension
, vol.38
, pp. 274-279
-
-
Taddei, S.1
Virdis, A.2
Ghiadoni, L.3
Salvetti, G.4
Bernini, G.5
Magagna, A.6
Salvetti, A.7
-
8
-
-
11144355198
-
Peroxisome proliferator-activated receptor α agonists increase nitric oxide synthase expression in vascular endothelial cells
-
Goya K, Sumitani S, Xu X, Kitamura T, Yamamoto H, Kurebayashi S, Saito H, Kouhara H, Kasayama S, Kawase I. Peroxisome proliferator-activated receptor α agonists increase nitric oxide synthase expression in vascular endothelial cells. Arterioscler Thromb Vasc Biol. 2004;24:658-663.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 658-663
-
-
Goya, K.1
Sumitani, S.2
Xu, X.3
Kitamura, T.4
Yamamoto, H.5
Kurebayashi, S.6
Saito, H.7
Kouhara, H.8
Kasayama, S.9
Kawase, I.10
-
9
-
-
34250704851
-
Long-term fenofibrate treatment impairs endothelium-dependent dilation to acetylcholine by altering the cyclooxygenase pathway
-
Blanco-Rivero J, Márquez-Rodas I, Xavier FE, Aras-López R, Arroyo-Villa I, Ferrer M, Balfagón G. Long-term fenofibrate treatment impairs endothelium-dependent dilation to acetylcholine by altering the cyclooxygenase pathway. Cardiovasc Res. 2007;75:398-407.
-
(2007)
Cardiovasc Res
, vol.75
, pp. 398-407
-
-
Blanco-Rivero, J.1
Márquez-Rodas, I.2
Xavier, F.E.3
Aras-López, R.4
Arroyo-Villa, I.5
Ferrer, M.6
Balfagón, G.7
-
10
-
-
27844587829
-
Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults
-
Eskurza I, Myerburgh LA, Kahn ZD, Seals DR. Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults. J Physiol (Lond). 2005;568(pt 3):1057-1065.
-
(2005)
J Physiol (Lond
, vol.568
, Issue.PART 3
, pp. 1057-1065
-
-
Eskurza, I.1
Myerburgh, L.A.2
Kahn, Z.D.3
Seals, D.R.4
-
11
-
-
43049181357
-
Methodological approaches to optimize reproducibility and power in clinical studies of flow-mediated dilation
-
Donald AE, Halcox JP, Charakida M, Storry C, Wallace SM, Cole TJ, Friberg P, Deanfield JE. Methodological approaches to optimize reproducibility and power in clinical studies of flow-mediated dilation. J Am Coll Cardiol. 2008;51:1959-1964.
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 1959-1964
-
-
Donald, A.E.1
Halcox, J.P.2
Charakida, M.3
Storry, C.4
Wallace, S.M.5
Cole, T.J.6
Friberg, P.7
Deanfield, J.E.8
-
12
-
-
68349106834
-
Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins
-
Silver AE, Christou DD, Donato AJ, Beske SD, Moreau KL, Magerko KA, Seals DR. Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins. J Vasc Res. 2010;47:1-8.
-
(2010)
J Vasc Res
, vol.47
, pp. 1-8
-
-
Silver, A.E.1
Christou, D.D.2
Donato, A.J.3
Beske, S.D.4
Moreau, K.L.5
Magerko, K.A.6
Seals, D.R.7
-
13
-
-
67650073156
-
Vascular endothelial dysfunction with aging: Endothelin-1 and endothelial nitric oxide synthase
-
Donato AJ, Gano LB, Eskurza I, Silver AE, Gates PE, Jablonski K, Seals DR. Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol. 2009;297:H425-H432.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Donato, A.J.1
Gano, L.B.2
Eskurza, I.3
Silver, A.E.4
Gates, P.E.5
Jablonski, K.6
Seals, D.R.7
-
14
-
-
0036890093
-
Effect of fenofibrate on brachial artery flow-mediated dilatation in type 2 diabetes mellitus
-
Playford DA, Watts GF, Best JD, Burke V. Effect of fenofibrate on brachial artery flow-mediated dilatation in type 2 diabetes mellitus. Am J Cardiol. 2002;90:1254-1257.
-
(2002)
Am J Cardiol
, vol.90
, pp. 1254-1257
-
-
Playford, D.A.1
Watts, G.F.2
Best, J.D.3
Burke, V.4
-
15
-
-
77954078831
-
Fenofibrate improves endothelial function in the brachial artery and forearm resistance arterioles of statin-treated type 2 diabetic patients
-
Hamilton SJ, Chew GT, Davis TM, Watts GF. Fenofibrate improves endothelial function in the brachial artery and forearm resistance arterioles of statin-treated type 2 diabetic patients. Clin Sci. 2010;118:607-615.
-
(2010)
Clin Sci
, vol.118
, pp. 607-615
-
-
Hamilton, S.J.1
Chew, G.T.2
Davis, T.M.3
Watts, G.F.4
-
16
-
-
0037324362
-
Short-term triglyceride lowering with fenofibrate improves vasodilator function in subjects with hypertriglyceridemia
-
Capell WH, DeSouza CA, Poirier P, Bell ML, Stauffer BL, Weil KM, Hernandez TL, Eckel RH. Short-term triglyceride lowering with fenofibrate improves vasodilator function in subjects with hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2003;23:307-313.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 307-313
-
-
Capell, W.H.1
Desouza, C.A.2
Poirier, P.3
Bell, M.L.4
Stauffer, B.L.5
Weil, K.M.6
Hernandez, T.L.7
Eckel, R.H.8
-
17
-
-
19944379835
-
Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia
-
Koh KK, Han SH, Quon MJ, Yeal Ahn J, Shin EK. Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia. Diabetes Care. 2005;28:1419-1424.
-
(2005)
Diabetes Care
, vol.28
, pp. 1419-1424
-
-
Koh, K.K.1
Han, S.H.2
Quon, M.J.3
Yeal Ahn, J.4
Shin, E.K.5
-
18
-
-
2342485967
-
Effects of fenofibrate on lipoproteins, vasomotor function, and serological markers of inflammation, plaque stabilization, and hemostasis
-
Kon Koh K, Yeal Ahn J, Hwan Han S, Kyu Jin D, Sik Kim H, Cheon Lee K, Kyun Shin E, Sakuma I. Effects of fenofibrate on lipoproteins, vasomotor function, and serological markers of inflammation, plaque stabilization, and hemostasis. Atherosclerosis. 2004;174:379-383.
-
(2004)
Atherosclerosis
, vol.174
, pp. 379-383
-
-
Kon Koh, K.1
Yeal Ahn, J.2
Hwan Han, S.3
Kyu Jin, D.4
Sik Kim, H.5
Cheon Lee, K.6
Kyun Shin, E.7
Sakuma, I.8
-
19
-
-
0034782457
-
Both fenofibrate and atorvastatin improve vascular reactivity in combined hyperlipidaemia (fenofibrate versus atorvastatin trial-FAT
-
Malik J, Melenovsky V, Wichterle D, Haas T, Simek J, Ceska R, Hradec J. Both fenofibrate and atorvastatin improve vascular reactivity in combined hyperlipidaemia (fenofibrate versus atorvastatin trial-FAT). Cardiovasc Res. 2001;52:290-298.
-
(2001)
Cardiovasc Res
, vol.52
, pp. 290-298
-
-
Malik, J.1
Melenovsky, V.2
Wichterle, D.3
Haas, T.4
Simek, J.5
Ceska, R.6
Hradec, J.7
-
20
-
-
79151482401
-
Effects of fenofibrate on plasma oxidized LDL and 8-isoprostane in a sub-cohort of GOLDN participants
-
Dong Y, Steffen BT, Cao J, Tsai AK, Ordovas J, Straka R, Zhou X, Kabagambe E, Hanson NQ, Arnett D, Tsai MY. Effects of fenofibrate on plasma oxidized LDL and 8-isoprostane in a sub-cohort of GOLDN participants. Atherosclerosis. 2011;214:422-425.
-
(2011)
Atherosclerosis
, vol.214
, pp. 422-425
-
-
Dong, Y.1
Steffen, B.T.2
Cao, J.3
Tsai, A.K.4
Ordovas, J.5
Straka, R.6
Zhou, X.7
Kabagambe, E.8
Hanson, N.Q.9
Arnett, D.10
Tsai, M.Y.11
-
22
-
-
84862916369
-
PPAR-α agonist fenofibrate upregulates tetrahydrobiopterin level through increasing the expression of guanosine 5'-triphosphate cyclohydrolase-I in human umbilical vein endothelial cells
-
Liu J, Lu C, Li F, Wang H, He L, Hao Y, Chen AF, An H, Wang X, Hong T, Wang G. PPAR-α agonist fenofibrate upregulates tetrahydrobiopterin level through increasing the expression of guanosine 5'-triphosphate cyclohydrolase-I in human umbilical vein endothelial cells. PPAR Res. 2011;2011:523520.
-
(2011)
PPAR Res 2011
, pp. 523520
-
-
Liu, J.1
Lu, C.2
Li, F.3
Wang, H.4
He, L.5
Hao, Y.6
Chen, A.F.7
An, H.8
Wang, X.9
Hong, T.10
Wang, G.11
-
23
-
-
0035962077
-
Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: A randomized controlled trial
-
VA-HIT Study Group Veterans Affairs High-Density Lipoprotein Intervention Trial
-
Robins SJ, Collins D, Wittes JT, Papademetriou V, Deedwania PC, Schaefer EJ, McNamara JR, Kashyap ML, Hershman JM, Wexler LF, Rubins HB; VA-HIT Study Group. Veterans Affairs High-Density Lipoprotein Intervention Trial. Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial. JAMA. 2001;285:1585-1591.
-
(2001)
JAMA
, vol.285
, pp. 1585-1591
-
-
Robins, S.J.1
Collins, D.2
Wittes, J.T.3
Papademetriou, V.4
Deedwania, P.C.5
Schaefer, E.J.6
McNamara, J.R.7
Kashyap, M.L.8
Hershman, J.M.9
Wexler, L.F.10
Rubins, H.B.11
-
24
-
-
0035941990
-
Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: The diabetes atherosclerosis intervention study, a randomised study
-
Diabetes Atherosclerosis Intervention Study Investigators
-
Diabetes Atherosclerosis Intervention Study Investigators. Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the diabetes atherosclerosis intervention study, a randomised study. Lancet. 2001;357:905-910.
-
(2001)
Lancet
, vol.357
, pp. 905-910
-
-
-
25
-
-
75149128670
-
Effects of long-term fenofibrate treatment on markers of renal function in type 2 diabetes: The FIELD Helsinki substudy
-
Forsblom C, Hiukka A, Leinonen ES, Sundvall J, Groop PH, Taskinen MR. Effects of long-term fenofibrate treatment on markers of renal function in type 2 diabetes: the FIELD Helsinki substudy. Diabetes Care. 2010;33:215-220.
-
(2010)
Diabetes Care
, vol.33
, pp. 215-220
-
-
Forsblom, C.1
Hiukka, A.2
Leinonen, E.S.3
Sundvall, J.4
Groop, P.H.5
Taskinen, M.R.6
-
26
-
-
49649117315
-
Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction
-
Chew GT, Watts GF, Davis TM, Stuckey BG, Beilin LJ, Thompson PL, Burke V, Currie PJ. Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction. Diabetes Care. 2008;31:1502-1509.
-
(2008)
Diabetes Care
, vol.31
, pp. 1502-1509
-
-
Chew, G.T.1
Watts, G.F.2
Davis, T.M.3
Stuckey, B.G.4
Beilin, L.J.5
Thompson, P.L.6
Burke, V.7
Currie, P.J.8
-
27
-
-
33845462872
-
PPARα activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans
-
Subramanian S, DeRosa MA, Bernal-Mizrachi C, Laffely N, Cade WT, Yarasheski KE, Cryer PE, Semenkovich CF. PPARα activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans. Am J Physiol Endocrinol Metab. 2006;291:E1365-E1371.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
-
-
Subramanian, S.1
Derosa, M.A.2
Bernal-Mizrachi, C.3
Laffely, N.4
Cade, W.T.5
Yarasheski, K.E.6
Cryer, P.E.7
Semenkovich, C.F.8
-
28
-
-
84859709385
-
PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats
-
Rodríguez-Vilarrupla A, Laviña B, García- Calderó H, Russo L, Rosado E, Roglans N, Bosch J, García- Pagán JC. PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats. J Hepatol. 2012;56:1033-1039.
-
(2012)
J Hepatol
, vol.56
, pp. 1033-1039
-
-
Rodríguez-Vilarrupla, A.1
Laviña, B.2
García- Calderó, H.3
Russo, L.4
Rosado, E.5
Roglans, N.6
Bosch, J.7
García- Pagán, J.C.8
-
29
-
-
1042286369
-
PPARα activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats
-
Diep QN, Benkirane K, Amiri F, Cohn JS, Endemann D, Schiffrin EL. PPARα activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats. J Mol Cell Cardiol. 2004;36:295-304.
-
(2004)
J Mol Cell Cardiol
, vol.36
, pp. 295-304
-
-
Diep, Q.N.1
Benkirane, K.2
Amiri, F.3
Cohn, J.S.4
Endemann, D.5
Schiffrin, E.L.6
-
30
-
-
0038720453
-
Peroxisome proliferator-activated receptor-α activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment
-
Deplanque D, Gelé P, Pétrault O, Six I, Furman C, Bouly M, Nion S, Dupuis B, Leys D, Fruchart JC, Cecchelli R, Staels B, Duriez P, Bordet R. Peroxisome proliferator-activated receptor-α activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment. J Neurosci. 2003;23:6264-6271.
-
(2003)
J Neurosci
, vol.23
, pp. 6264-6271
-
-
Deplanque, D.1
Gelé, P.2
Pétrault, O.3
Six, I.4
Furman, C.5
Bouly, M.6
Nion, S.7
Dupuis, B.8
Leys, D.9
Fruchart, J.C.10
Cecchelli, R.11
Staels, B.12
Duriez, P.13
Bordet, R.14
-
31
-
-
77957985215
-
Chronic treatment with fibrates elevates superoxide dismutase in adult mouse brain microvessels
-
Wang G, Liu X, Guo Q, Namura S. Chronic treatment with fibrates elevates superoxide dismutase in adult mouse brain microvessels. Brain Res. 2010;1359:247-255.
-
(2010)
Brain Res
, vol.1359
, pp. 247-255
-
-
Wang, G.1
Liu, X.2
Guo, Q.3
Namura, S.4
-
32
-
-
73949118640
-
Fenofibrate improves cerebral blood flow after middle cerebral artery occlusion in mice
-
Guo Q, Wang G, Namura S. Fenofibrate improves cerebral blood flow after middle cerebral artery occlusion in mice. J Cereb Blood Flow Metab. 2010;30:70-78.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 70-78
-
-
Guo, Q.1
Wang, G.2
Namura, S.3
-
33
-
-
84864956001
-
Age-related differences in the effects of α and γ peroxisome proliferator-activated receptor subtype agonists on endothelial vasodilation in human microvessels
-
Angulo J, Vallejo S, El Assar M, García-Septiem J, Sánchez-Ferrer CF, Rodríguez-Mañas L. Age-related differences in the effects of α and γ peroxisome proliferator-activated receptor subtype agonists on endothelial vasodilation in human microvessels. Exp Gerontol. 2012;47:734-740.
-
(2012)
Exp Gerontol
, vol.47
, pp. 734-740
-
-
Angulo, J.1
Vallejo, S.2
El Assar, M.3
García-Septiem, J.4
Sánchez-Ferrer, C.F.5
Rodríguez-Mañas, L.6
-
34
-
-
0032484123
-
Peroxisome proliferator-activated receptor α activation modulates cellular redox status, represses nuclear factor-κB signaling, and reduces inflammatory cytokine production in aging
-
Poynter ME, Daynes RA. Peroxisome proliferator-activated receptor α activation modulates cellular redox status, represses nuclear factor-κB signaling, and reduces inflammatory cytokine production in aging. J Biol Chem. 1998;273:32833-32841.
-
(1998)
J Biol Chem
, vol.273
, pp. 32833-32841
-
-
Poynter, M.E.1
Daynes, R.A.2
-
35
-
-
0036839504
-
Aging-induced decrease in the PPAR-α level in hearts is improved by exercise training
-
Iemitsu M, Miyauchi T, Maeda S, Tanabe T, Takanashi M, Irukayama-Tomobe Y, Sakai S, Ohmori H, Matsuda M, Yamaguchi I. Aging-induced decrease in the PPAR-α level in hearts is improved by exercise training. Am J Physiol Heart Circ Physiol. 2002;283:H1750-H1760.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Iemitsu, M.1
Miyauchi, T.2
Maeda, S.3
Tanabe, T.4
Takanashi, M.5
Irukayama-Tomobe, Y.6
Sakai, S.7
Ohmori, H.8
Matsuda, M.9
Yamaguchi, I.10
-
36
-
-
7444272441
-
Modulation of PPAR in aging, inflammation, and calorie restriction
-
Sung B, Park S, Yu BP, Chung HY. Modulation of PPAR in aging, inflammation, and calorie restriction. J Gerontol A Biol Sci Med Sci. 2004;59:997-1006.
-
(2004)
J Gerontol A Biol Sci Med Sci
, vol.59
, pp. 997-1006
-
-
Sung, B.1
Park, S.2
Yu, B.P.3
Chung, H.Y.4
-
37
-
-
2542461241
-
Optimal low-density lipoprotein is 50 to 70 mg/dl: Lower is better and physiologically normal
-
O'Keefe JH Jr, Cordain L, Harris WH, Moe RM, Vogel R. Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal. J Am Coll Cardiol. 2004;43:2142-2146.
-
(2004)
J Am Coll Cardiol
, vol.43
, pp. 2142-2146
-
-
O'Keefe Jr., J.H.1
Cordain, L.2
Harris, W.H.3
Moe, R.M.4
Vogel, R.5
-
38
-
-
56749106312
-
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
-
JUPITER Study Group
-
Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med. 2008;359:2195-2207.
-
(2008)
N Engl J Med
, vol.359
, pp. 2195-2207
-
-
Ridker, P.M.1
Danielson, E.2
Fonseca, F.A.3
Genest, J.4
Gotto Jr., A.M.5
Kastelein, J.J.6
Koenig, W.7
Libby, P.8
Lorenzatti, A.J.9
MacFadyen, J.G.10
Nordestgaard, B.G.11
Shepherd, J.12
Willerson, J.T.13
Glynn, R.J.14
|