SIRT3 deficiency exacerbates ischemia-reperfusion injury: Implication for aged hearts

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 12, 2014, Pages

  Porter, George A ^a   Urciuoli, William R ^a   Brookes, Paul S ^a   Nadtochiy, Sergiy M ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Acetylation; Aging; Heart; Ischemia; Mitochondria; Reperfusion; SIRT3

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SIRTUIN 3; SMALL INTERFERING RNA;

ACETYLATION; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENSITOMETRY; DISEASE EXACERBATION; EMBRYO; ENZYME ACTIVITY; ENZYME DEFICIENCY; GENE SILENCING; HEART MITOCHONDRION; IMMUNOBLOTTING; IN VITRO STUDY; ISOLATED HEART; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; WILD TYPE;

ACETYLATION; AGING; HEART; ISCHEMIA; MITOCHONDRIA; REPERFUSION; SIRT3;

AGING; ANIMALS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HEART RATE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; RISK FACTORS; SIRTUIN 3; VENTRICULAR FUNCTION, LEFT;

EID: 84902687763     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00027.2014     Document Type: Article

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