Beneficial cardiac effects of caloric restriction are lost with age in a murine model of obesity

Journal of Cardiovascular Translational Research

Volumn 6, Issue 3, 2013, Pages 436-445

  Alghatrif, Majd ^a   Watts, Vabren L ^a   Niu, Xiaolin ^a,b   Halushka, Marc ^a   Miller, Karen L ^a   Vandegaer, Konrad ^a   Bedja, Djahida ^a   Fox Talbot, Karen ^a   Bielawska, Alicja ^c   Gabrielson, Kathleen L ^a   Barouch, Lili A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Caloric restriction; Diastolic dysfunction; Lipotoxicity; Obesity; Steatosis

Indexed keywords

CERAMIDE; FATTY ACID; NITRIC OXIDE SYNTHASE; PROTEIN KINASE B; SUPEROXIDE; TRIACYLGLYCEROL;

AGE DISTRIBUTION; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; HEART FUNCTION; HEART PROTECTION; HEART WEIGHT; HISTOPATHOLOGY; LIPID ANALYSIS; LIPOTOXICITY; MOUSE; MYOCARDIAL STEATOSIS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STEATOSIS; WESTERN BLOTTING;

AGE FACTORS; ANIMALS; CALORIC RESTRICTION; CERAMIDES; DIASTOLE; DISEASE MODELS, ANIMAL; FATTY ACIDS, NONESTERIFIED; MICE; MICE, INBRED C57BL; MYOCARDIUM; NITRIC OXIDE SYNTHASE; OBESITY; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SUPEROXIDE DISMUTASE; TIME FACTORS; TRIGLYCERIDES; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT; WEIGHT LOSS;

ANIMALIA; MURINAE; MUS;

EID: 84877731498     PISSN: 19375387     EISSN: 19375395     Source Type: Journal    
DOI: 10.1007/s12265-013-9453-4     Document Type: Article

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