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Volumn 32, Issue 5, 2013, Pages 1167-1177

Dietary curcumin ameliorates aging-related cerebrovascular dysfunction through the AMPK/uncoupling protein 2 pathway

Author keywords

5' AMP activated protein kinase; Aging; Cerebrovascular dysfunction; Curcumin; Uncoupling protein 2

Indexed keywords

ADENYLATE KINASE; CURCUMIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2;

EID: 84890741956     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000354516     Document Type: Article
Times cited : (98)

References (38)
  • 3
    • 78149274971 scopus 로고    scopus 로고
    • Aging and cerebrovascular dysfunction: Contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy
    • Vasilevko V, Passos GF, Quiring D, Head E, Kim RC, Fisher M, Cribbs DH: Aging and cerebrovascular dysfunction: Contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy. Ann N Y Acad Sci 2010;1207:58-70.
    • (2010) Ann N y Acad Sci , vol.1207 , pp. 58-70
    • Vasilevko, V.1    Passos, G.F.2    Quiring, D.3    Head, E.4    Kim, R.C.5    Fisher, M.6    Cribbs, D.H.7
  • 7
    • 25144476923 scopus 로고    scopus 로고
    • Physiological functions of the mitochondrial uncoupling proteins ucp2 and ucp3
    • Brand MD, Esteves TC: Physiological functions of the mitochondrial uncoupling proteins ucp2 and ucp3. Cell Metab 2005;2:85-93.
    • (2005) Cell Metab , vol.2 , pp. 85-93
    • Brand, M.D.1    Esteves, T.C.2
  • 8
    • 80051783174 scopus 로고    scopus 로고
    • Uncoupling proteins and the control of mitochondrial reactive oxygen species production
    • Mailloux RJ, Harper ME: Uncoupling proteins and the control of mitochondrial reactive oxygen species production. Free Radic Biol Med 2011;51:1106-1115.
    • (2011) Free Radic Biol Med , vol.51 , pp. 1106-1115
    • Mailloux, R.J.1    Harper, M.E.2
  • 9
    • 27644448810 scopus 로고    scopus 로고
    • Mitochondrial uncoupling proteins in the cns: In support of function and survival
    • Andrews ZB, Diano S, Horvath TL: Mitochondrial uncoupling proteins in the cns: In support of function and survival. Nat Rev Neurosci 2005;6:829-840.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 829-840
    • Andrews, Z.B.1    Diano, S.2    Horvath, T.L.3
  • 10
    • 46449089402 scopus 로고    scopus 로고
    • Anti-obesity effects of juniperus chinensis extract are associated with increased amp-activated protein kinase expression and phosphorylation in the visceral adipose tissue of rats
    • Kim SJ, Jung JY, Kim HW, Park T: Anti-obesity effects of juniperus chinensis extract are associated with increased amp-activated protein kinase expression and phosphorylation in the visceral adipose tissue of rats. Biol Pharm Bull 2008;31:1415-1421.
    • (2008) Biol Pharm Bull , vol.31 , pp. 1415-1421
    • Kim, S.J.1    Jung, J.Y.2    Kim, H.W.3    Park, T.4
  • 11
    • 38049120264 scopus 로고    scopus 로고
    • Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysisderived pyruvate utilization
    • Pecqueur C, Bui T, Gelly C, Hauchard J, Barbot C, Bouillaud F, Ricquier D, Miroux B, Thompson CB: Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysisderived pyruvate utilization. FASEB J 2008;22:9-18.
    • (2008) FASEB J , vol.22 , pp. 9-18
    • Pecqueur, C.1    Bui, T.2    Gelly, C.3    Hauchard, J.4    Barbot, C.5    Bouillaud, F.6    Ricquier, D.7    Miroux, B.8    Thompson, C.B.9
  • 12
    • 77955773056 scopus 로고    scopus 로고
    • Uncoupling protein 2 ablation exacerbates high-salt intakeinduced vascular dysfunction
    • Ma S, Ma L, Yang D, Luo Z, Hao X, Liu D, Zhu Z: Uncoupling protein 2 ablation exacerbates high-salt intakeinduced vascular dysfunction. Am J Hypertens 2010;23:822-828.
    • (2010) Am J Hypertens , vol.23 , pp. 822-828
    • Ma, S.1    Ma, L.2    Yang, D.3    Luo, Z.4    Hao, X.5    Liu, D.6    Zhu, Z.7
  • 14
    • 63449141267 scopus 로고    scopus 로고
    • Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice
    • Moukdar F, Robidoux J, Lyght O, Pi J, Daniel KW, Collins S: Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice. J Lipid Res 2009;50:59-70.
    • (2009) J Lipid Res , vol.50 , pp. 59-70
    • Moukdar, F.1    Robidoux, J.2    Lyght, O.3    Pi, J.4    Daniel, K.W.5    Collins, S.6
  • 16
    • 84863115185 scopus 로고    scopus 로고
    • Discovery of curcumin, a component of golden spice, and its miraculous biological activities
    • Gupta SC, Patchva S, Koh W, Aggarwal BB: Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol 2012;39:283-299.
    • (2012) Clin Exp Pharmacol Physiol , vol.39 , pp. 283-299
    • Gupta, S.C.1    Patchva, S.2    Koh, W.3    Aggarwal, B.B.4
  • 18
    • 66049139240 scopus 로고    scopus 로고
    • Dietary curcumin supplementation counteracts reduction in levels of molecules involved in energy homeostasis after brain trauma
    • Sharma S, Zhuang Y, Ying Z, Wu A, Gomez-Pinilla F: Dietary curcumin supplementation counteracts reduction in levels of molecules involved in energy homeostasis after brain trauma. Neuroscience 2009;161:1037-1044.
    • (2009) Neuroscience , vol.161 , pp. 1037-1044
    • Sharma, S.1    Zhuang, Y.2    Ying, Z.3    Wu, A.4    Gomez-Pinilla, F.5
  • 19
    • 0346850976 scopus 로고    scopus 로고
    • Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats
    • Thiyagarajan M, Sharma SS: Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Life Sci 2004;74:969-985.
    • (2004) Life Sci , vol.74 , pp. 969-985
    • Thiyagarajan, M.1    Sharma, S.S.2
  • 21
    • 84861235129 scopus 로고    scopus 로고
    • Sustained activation of ampk ameliorates ageassociated vascular endothelial dysfunction via a nitric oxide-independent mechanism
    • Lesniewski LA, Zigler MC, Durrant JR, Donato AJ, Seals DR: Sustained activation of ampk ameliorates ageassociated vascular endothelial dysfunction via a nitric oxide-independent mechanism. Mech Ageing Dev 2012;133:368-371.
    • (2012) Mech Ageing Dev , vol.133 , pp. 368-371
    • Lesniewski, L.A.1    Zigler, M.C.2    Durrant, J.R.3    Donato, A.J.4    Seals, D.R.5
  • 23
    • 80054968152 scopus 로고    scopus 로고
    • Activation of transient receptor potential vanilloid 1 by dietary capsaicin delays the onset of stroke in stroke-prone spontaneously hypertensive rats
    • Xu X, Wang P, Zhao Z, Cao T, He H, Luo Z, Zhong J, Gao F, Zhu Z, Li L, Yan Z, Chen J, Ni Y, Liu D: Activation of transient receptor potential vanilloid 1 by dietary capsaicin delays the onset of stroke in stroke-prone spontaneously hypertensive rats. Stroke 2011;42:3245-3251.
    • (2011) Stroke , vol.42 , pp. 3245-3251
    • Xu, X.1    Wang, P.2    Zhao, Z.3    Cao, T.4    He, H.5    Luo, Z.6    Zhong, J.7    Gao, F.8    Zhu, Z.9    Li, L.10    Yan, Z.11    Chen, J.12    Ni, Y.13    Liu, D.14
  • 25
    • 84864377753 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1 activation enhances gut glucagon-like peptide-1 secretion and improves glucose homeostasis
    • Wang P, Yan Z, Zhong J, Chen J, Ni Y, Li L, Ma L, Zhao Z, Liu D, Zhu Z: Transient receptor potential vanilloid 1 activation enhances gut glucagon-like peptide-1 secretion and improves glucose homeostasis. Diabetes 2012;61:2155-2165.
    • (2012) Diabetes , vol.61 , pp. 2155-2165
    • Wang, P.1    Yan, Z.2    Zhong, J.3    Chen, J.4    Ni, Y.5    Li, L.6    Ma, L.7    Zhao, Z.8    Liu, D.9    Zhu, Z.10
  • 28
    • 77957363916 scopus 로고    scopus 로고
    • Exogenous antioxidants-double-edged swords in cellular redox state: Health beneficial effects at physiologic doses versus deleterious effects at high doses
    • Bouayed J, Bohn T: Exogenous antioxidants-double-edged swords in cellular redox state: Health beneficial effects at physiologic doses versus deleterious effects at high doses. Oxid Med Cell Longev 2010;3:228-237.
    • (2010) Oxid Med Cell Longev , vol.3 , pp. 228-237
    • Bouayed, J.1    Bohn, T.2
  • 29
    • 0033949848 scopus 로고    scopus 로고
    • Activation of amp-activated protein kinase increases mitochondrial enzymes in skeletal muscle
    • Winder WW, Holmes BF, Rubink DS, Jensen EB, Chen M, Holloszy JO: Activation of amp-activated protein kinase increases mitochondrial enzymes in skeletal muscle. J Appl Physiol 2000;88:2219-2226.
    • (2000) J Appl Physiol , vol.88 , pp. 2219-2226
    • Winder, W.W.1    Holmes, B.F.2    Rubink, D.S.3    Jensen, E.B.4    Chen, M.5    Holloszy, J.O.6
  • 31
    • 84855182851 scopus 로고    scopus 로고
    • Amp-activated protein kinase (ampk) controls the aging process via an integrated signaling network
    • Salminen A, Kaarniranta K: Amp-activated protein kinase (ampk) controls the aging process via an integrated signaling network. Ageing Res Rev 2012;11:230-241.
    • (2012) Ageing Res Rev , vol.11 , pp. 230-241
    • Salminen, A.1    Kaarniranta, K.2
  • 32
    • 77949318560 scopus 로고    scopus 로고
    • Metabolic reprogramming, caloric restriction and aging
    • Anderson RM, Weindruch R: Metabolic reprogramming, caloric restriction and aging. Trends Endocrinol Metab 2010;21:134-141.
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 134-141
    • Anderson, R.M.1    Weindruch, R.2
  • 33
    • 69849107217 scopus 로고    scopus 로고
    • Caloric restriction, sirt1 and longevity
    • Canto C, Auwerx J: Caloric restriction, sirt1 and longevity. Trends Endocrinol Metab 2009;20:325-331.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 325-331
    • Canto, C.1    Auwerx, J.2
  • 34
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span-from yeast to humans
    • Fontana L, Partridge L, Longo VD: Extending healthy life span-from yeast to humans. Science 2010;328:321-326.
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 35
    • 63549108476 scopus 로고    scopus 로고
    • Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in c
    • Greer EL, Brunet A: Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in c. Elegans. Aging Cell 2009;8:113-127.
    • (2009) Elegans. Aging Cell , vol.8 , pp. 113-127
    • Greer, E.L.1    Brunet, A.2
  • 36
    • 23944494249 scopus 로고    scopus 로고
    • Targeted expression of the human uncoupling protein 2 (hucp2) to adult neurons extends life span in the fly
    • Fridell YW, Sanchez-Blanco A, Silvia BA, Helfand SL: Targeted expression of the human uncoupling protein 2 (hucp2) to adult neurons extends life span in the fly. Cell metab 2005;1:145-152.
    • (2005) Cell Metab , vol.1 , pp. 145-152
    • Fridell, Y.W.1    Sanchez-Blanco, A.2    Silvia, B.A.3    Helfand, S.L.4
  • 37
    • 70350708314 scopus 로고    scopus 로고
    • Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension
    • Chan SH, Wu CA, Wu KL, Ho YH, Chang AY, Chan JY: Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension. Circ Res 2009;105:886-896.
    • (2009) Circ Res , vol.105 , pp. 886-896
    • Chan, S.H.1    Wu, C.A.2    Wu, K.L.3    Ho, Y.H.4    Chang, A.Y.5    Chan, J.Y.6
  • 38
    • 62749098304 scopus 로고    scopus 로고
    • Vascular action of polyphenols
    • Ghosh D, Scheepens A: Vascular action of polyphenols. Mol Nutr Food Res 2009;53:322-331.
    • (2009) Mol Nutr Food Res , vol.53 , pp. 322-331
    • Ghosh, D.1    Scheepens, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.