-
1
-
-
0032704549
-
Influence of age on hypoxia/reoxygenation-induced DNA fragmentation and bcl-2, bcl-xl, bax and fas in the rat heart and brain
-
Azhar G., Liu L., Zhang X., Wei J.Y. Influence of age on hypoxia/reoxygenation-induced DNA fragmentation and bcl-2, bcl-xl, bax and fas in the rat heart and brain. Mech. Ageing Dev. 1999, 112:5-25.
-
(1999)
Mech. Ageing Dev.
, vol.112
, pp. 5-25
-
-
Azhar, G.1
Liu, L.2
Zhang, X.3
Wei, J.Y.4
-
2
-
-
34147188924
-
Loss of ischemic preconditioning's cardioprotection in aged mouse hearts is associated with reduced gap junctional and mitochondrial levels of connexin 43
-
Boengler K., Konietzka I., Buechert A., Heinen Y., Garcia-Dorado D., Heusch G., Schulz R. Loss of ischemic preconditioning's cardioprotection in aged mouse hearts is associated with reduced gap junctional and mitochondrial levels of connexin 43. Am. J. Physiol. Heart Circ. Physiol. 2007, 292:H1764-H1769.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.292
-
-
Boengler, K.1
Konietzka, I.2
Buechert, A.3
Heinen, Y.4
Garcia-Dorado, D.5
Heusch, G.6
Schulz, R.7
-
4
-
-
78349313123
-
Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms
-
Brinks H., Boucher M., Gao E., Chuprun J.K., Pesant S., Raake P.W., Huang Z.M., Wang X., Qiu G., Gumpert A., Harris D.M., Eckhart A.D., Most P., Koch W.J. Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms. Circ. Res. 2010, 107:1140-1149.
-
(2010)
Circ. Res.
, vol.107
, pp. 1140-1149
-
-
Brinks, H.1
Boucher, M.2
Gao, E.3
Chuprun, J.K.4
Pesant, S.5
Raake, P.W.6
Huang, Z.M.7
Wang, X.8
Qiu, G.9
Gumpert, A.10
Harris, D.M.11
Eckhart, A.D.12
Most, P.13
Koch, W.J.14
-
6
-
-
84876413668
-
Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting
-
Chen M., Sato P.Y., Chuprun J.K., Peroutka R.J., Otis N.J., Ibetti J., Pan S., Sheu S.S., Gao E., Koch W.J. Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting. Circ. Res. 2013, 112:1121-1134.
-
(2013)
Circ. Res.
, vol.112
, pp. 1121-1134
-
-
Chen, M.1
Sato, P.Y.2
Chuprun, J.K.3
Peroutka, R.J.4
Otis, N.J.5
Ibetti, J.6
Pan, S.7
Sheu, S.S.8
Gao, E.9
Koch, W.J.10
-
7
-
-
10944220835
-
Caveolin-1 as a prime modulator of aging: a new modality for phenotypic restoration?
-
Cho K.A., Park S.C. Caveolin-1 as a prime modulator of aging: a new modality for phenotypic restoration?. Mech. Ageing Dev. 2005, 126:105-110.
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 105-110
-
-
Cho, K.A.1
Park, S.C.2
-
8
-
-
84859896427
-
Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities
-
Dutta D., Calvani R., Bernabei R., Leeuwenburgh C., Marzetti E. Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities. Circ. Res. 2012, 110:1125-1138.
-
(2012)
Circ. Res.
, vol.110
, pp. 1125-1138
-
-
Dutta, D.1
Calvani, R.2
Bernabei, R.3
Leeuwenburgh, C.4
Marzetti, E.5
-
10
-
-
26444551639
-
Inhibition of phosphatase activity enhances preconditioning and limits cell death in the ischemic/reperfused aged rat heart
-
Fenton R.A., Dickson E.W., Dobson J.G. Inhibition of phosphatase activity enhances preconditioning and limits cell death in the ischemic/reperfused aged rat heart. Life Sci. 2005, 77:3375-3388.
-
(2005)
Life Sci.
, vol.77
, pp. 3375-3388
-
-
Fenton, R.A.1
Dickson, E.W.2
Dobson, J.G.3
-
11
-
-
77952634878
-
1-receptor-mediated adenoprotection involves phospholipase C, PKC-epsilon, and p38 MAPK, but not HSP27
-
1-receptor-mediated adenoprotection involves phospholipase C, PKC-epsilon, and p38 MAPK, but not HSP27. Am. J. Physiol. Heart Circ. Physiol. 2010, 298:H1671-H1678.
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.298
-
-
Fenton, R.A.1
Shea, L.G.2
Doddi, C.3
Dobson, J.G.4
-
12
-
-
37549038706
-
Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning
-
Ferdinandy P., Schulz R., Baxter G.F. Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning. Pharmacol. Rev. 2007, 59:418-458.
-
(2007)
Pharmacol. Rev.
, vol.59
, pp. 418-458
-
-
Ferdinandy, P.1
Schulz, R.2
Baxter, G.F.3
-
13
-
-
33745234137
-
NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase
-
Förster K., Paul I., Solenkova N., Staudt A., Cohen M.V., Downey J.M., Felix S.B., Krieg T. NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Basic Res. Cardiol. 2006, 101:319-326.
-
(2006)
Basic Res. Cardiol.
, vol.101
, pp. 319-326
-
-
Förster, K.1
Paul, I.2
Solenkova, N.3
Staudt, A.4
Cohen, M.V.5
Downey, J.M.6
Felix, S.B.7
Krieg, T.8
-
14
-
-
84868278452
-
Mitochondria-localized caveolin in adaptation to cellular stress and injury
-
Fridolfsson H.N., Kawaraguchi Y., Ali S.S., Panneerselvam M., Niesman I.R., Finley J.C., Kellerhals S.E., Migita M.Y., Okada H., Moreno A.L., Jennings M., Kidd M.W., Bonds J.A., Balijepalli R.C., Ross R.S., Patel P.M., Miyanohara A., Chen Q., Lesnefsky E.J., Head B.P., Roth D.M., Insel P.A., Patel H.H. Mitochondria-localized caveolin in adaptation to cellular stress and injury. FASEB J. 2012, 26:4637-4649.
-
(2012)
FASEB J.
, vol.26
, pp. 4637-4649
-
-
Fridolfsson, H.N.1
Kawaraguchi, Y.2
Ali, S.S.3
Panneerselvam, M.4
Niesman, I.R.5
Finley, J.C.6
Kellerhals, S.E.7
Migita, M.Y.8
Okada, H.9
Moreno, A.L.10
Jennings, M.11
Kidd, M.W.12
Bonds, J.A.13
Balijepalli, R.C.14
Ross, R.S.15
Patel, P.M.16
Miyanohara, A.17
Chen, Q.18
Lesnefsky, E.J.19
Head, B.P.20
Roth, D.M.21
Insel, P.A.22
Patel, H.H.23
more..
-
15
-
-
84878970264
-
Caveolin and caveolae in age associated cardiovascular disease
-
Fridolfsson H.N., Patel H.H. Caveolin and caveolae in age associated cardiovascular disease. J Geriatr. Cardiol. 2013, 10:66-74.
-
(2013)
J Geriatr. Cardiol.
, vol.10
, pp. 66-74
-
-
Fridolfsson, H.N.1
Patel, H.H.2
-
16
-
-
33748345801
-
2+-dependent manner
-
2+-dependent manner. J. Cell. Mol. Med. 2006, 10:216-224.
-
(2006)
J. Cell. Mol. Med.
, vol.10
, pp. 216-224
-
-
Fujita, T.1
Otsu, K.2
Oshikawa, J.3
Hori, H.4
Kitamura, H.5
Ito, T.6
Umemura, S.7
Minamisawa, S.8
Ishikawa, Y.9
-
17
-
-
79957865612
-
Institute of Medicine (US) Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries. Promoting Cardiovascular Health in the Developing World: A Critical Challenge to Achieve Global Health
-
National Academies Press (US), Washington (DC), V. Fuster, B.B. Kelly (Eds.)
-
Institute of Medicine (US) Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries. Promoting Cardiovascular Health in the Developing World: A Critical Challenge to Achieve Global Health. Epidemiology of Cardiovascular Disease 2010, 2. National Academies Press (US), Washington (DC). V. Fuster, B.B. Kelly (Eds.).
-
(2010)
Epidemiology of Cardiovascular Disease
, vol.2
-
-
-
18
-
-
12344309431
-
Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?
-
Gems D., McElwee J.J. Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?. Mech. Ageing Dev. 2005, 126:381-387.
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 381-387
-
-
Gems, D.1
McElwee, J.J.2
-
19
-
-
1842841258
-
Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts
-
Gross E.R., Hsu A.K., Gross G.J. Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts. Circ. Res. 2004, 94:960-966.
-
(2004)
Circ. Res.
, vol.94
, pp. 960-966
-
-
Gross, E.R.1
Hsu, A.K.2
Gross, G.J.3
-
20
-
-
0020626413
-
The isolated human pectinate muscle: a reliable preparation of human cardiac tissue
-
Guo Z., Levi R., Aaronson L. The isolated human pectinate muscle: a reliable preparation of human cardiac tissue. J. Pharmacol. Toxicol. Methods 1983, 9:127-135.
-
(1983)
J. Pharmacol. Toxicol. Methods
, vol.9
, pp. 127-135
-
-
Guo, Z.1
Levi, R.2
Aaronson, L.3
-
21
-
-
0030826778
-
Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury
-
Halestrap A.P., Connern C.P., Griffiths E.J., Kerr P.M. Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury. Mol. Cell. Biochem. 1997, 174:167-172.
-
(1997)
Mol. Cell. Biochem.
, vol.174
, pp. 167-172
-
-
Halestrap, A.P.1
Connern, C.P.2
Griffiths, E.J.3
Kerr, P.M.4
-
22
-
-
33745216272
-
Stress resistance and aging: influence of genes and nutrition
-
Harper J.M., Salmon A.B., Chang Y., Bonkowski M., Bartke A., Miller R.A. Stress resistance and aging: influence of genes and nutrition. Mech. Ageing Dev. 2006, 127:687-694.
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 687-694
-
-
Harper, J.M.1
Salmon, A.B.2
Chang, Y.3
Bonkowski, M.4
Bartke, A.5
Miller, R.A.6
-
23
-
-
30744432149
-
Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium
-
Hassouna A., Loubani M., Matata B.M., Fowler A., Standen N.B., Galinanes M. Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium. Cardiovasc. Res. 2006, 69:450-458.
-
(2006)
Cardiovasc. Res.
, vol.69
, pp. 450-458
-
-
Hassouna, A.1
Loubani, M.2
Matata, B.M.3
Fowler, A.4
Standen, N.B.5
Galinanes, M.6
-
24
-
-
24144462378
-
G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes
-
Head B.P., Patel H.H., Roth D.M., Lai N.C., Niesman I.R., Farquhar M.G., Insel P.A. G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes. J. Biol. Chem. 2005, 280:31036-31044.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31036-31044
-
-
Head, B.P.1
Patel, H.H.2
Roth, D.M.3
Lai, N.C.4
Niesman, I.R.5
Farquhar, M.G.6
Insel, P.A.7
-
25
-
-
78650832142
-
Loss of caveolin-1 accelerates neurodegeneration and aging
-
Head B.P., Peart J.N., Panneerselvam M., Yokoyama T., Pearn M.L., Niesman I.R., Bonds J.A., Schilling J.M., Miyanohara A., Headrick J., Ali S.S., Roth D.M., Patel P.M., Patel H.H. Loss of caveolin-1 accelerates neurodegeneration and aging. PLoS One. 2010, 5(12):e15697.
-
(2010)
PLoS One.
, vol.5
, Issue.12
-
-
Head, B.P.1
Peart, J.N.2
Panneerselvam, M.3
Yokoyama, T.4
Pearn, M.L.5
Niesman, I.R.6
Bonds, J.A.7
Schilling, J.M.8
Miyanohara, A.9
Headrick, J.10
Ali, S.S.11
Roth, D.M.12
Patel, P.M.13
Patel, H.H.14
-
26
-
-
0032128428
-
Aging impairs functional, metabolic and ionic recovery from ischemia-reperfusion and hypoxia-reoxygenation
-
Headrick J.P. Aging impairs functional, metabolic and ionic recovery from ischemia-reperfusion and hypoxia-reoxygenation. J. Mol. Cell. Cardiol. 1998, 30:1415-1430.
-
(1998)
J. Mol. Cell. Cardiol.
, vol.30
, pp. 1415-1430
-
-
Headrick, J.P.1
-
28
-
-
37349065075
-
The regulation of mitochondrial respiration by opening of mKCa channels is age-dependent
-
Heinen A., Winning A., Schlack W., Hollmann M.W., Preckel B., Frässdorf J., Weber N.C. The regulation of mitochondrial respiration by opening of mKCa channels is age-dependent. Eur. J. Pharmacol. 2008, 578:108-113.
-
(2008)
Eur. J. Pharmacol.
, vol.578
, pp. 108-113
-
-
Heinen, A.1
Winning, A.2
Schlack, W.3
Hollmann, M.W.4
Preckel, B.5
Frässdorf, J.6
Weber, N.C.7
-
29
-
-
79957577739
-
Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling
-
Horikawa Y.T., Panneerselvam M., Kawaraguchi Y., Tsutsumi Y.M., Ali S.S., Balijepalli R.C., Murray F., Head B.P., Niesman I.R., Rieg T., Vallon V., Insel P.A., Patel H.H., Roth D.M. Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling. J. Am. Coll. Cardiol. 2011, 57:2273-2283.
-
(2011)
J. Am. Coll. Cardiol.
, vol.57
, pp. 2273-2283
-
-
Horikawa, Y.T.1
Panneerselvam, M.2
Kawaraguchi, Y.3
Tsutsumi, Y.M.4
Ali, S.S.5
Balijepalli, R.C.6
Murray, F.7
Head, B.P.8
Niesman, I.R.9
Rieg, T.10
Vallon, V.11
Insel, P.A.12
Patel, H.H.13
Roth, D.M.14
-
30
-
-
78649751904
-
Cyclosporine A administered during reperfusion fails to restore cardioprotection in prediabetic Zucker obese rats in vivo
-
Huhn R., Heinen A., Hollmann M.W., Schlack W., Preckel B., Weber N.C. Cyclosporine A administered during reperfusion fails to restore cardioprotection in prediabetic Zucker obese rats in vivo. Nutr. Metab. Cardiovasc. Dis. 2010, 20:706-712.
-
(2010)
Nutr. Metab. Cardiovasc. Dis.
, vol.20
, pp. 706-712
-
-
Huhn, R.1
Heinen, A.2
Hollmann, M.W.3
Schlack, W.4
Preckel, B.5
Weber, N.C.6
-
31
-
-
33846796290
-
Estrogen deficiency decreases ischemic tolerance in the aged rat heart: roles of PKCdelta, PKCepsilon, Akt, and GSK3beta
-
Hunter J.C., Kostyak J.C., Novotny J.L., Simpson A.M., Korzick D.H. Estrogen deficiency decreases ischemic tolerance in the aged rat heart: roles of PKCdelta, PKCepsilon, Akt, and GSK3beta. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292:R800-R809.
-
(2007)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.292
-
-
Hunter, J.C.1
Kostyak, J.C.2
Novotny, J.L.3
Simpson, A.M.4
Korzick, D.H.5
-
32
-
-
67649882599
-
Role of glycogen synthase kinase-3β in cardioprotection
-
Juhaszova M., Zorov D.B., Yaniv Y., Nuss H.B., Wang S., Sollott S.J. Role of glycogen synthase kinase-3β in cardioprotection. Circ. Res. 2009, 104:1240-1252.
-
(2009)
Circ. Res.
, vol.104
, pp. 1240-1252
-
-
Juhaszova, M.1
Zorov, D.B.2
Yaniv, Y.3
Nuss, H.B.4
Wang, S.5
Sollott, S.J.6
-
33
-
-
42549134137
-
GRK2-dependent desensitization downstream of G proteins
-
Jurado-Pueyo M., Campos P.M., Mayor F., Murga C. GRK2-dependent desensitization downstream of G proteins. J. Recept. Signal Transduct. Res. 2008, 28:59-70.
-
(2008)
J. Recept. Signal Transduct. Res.
, vol.28
, pp. 59-70
-
-
Jurado-Pueyo, M.1
Campos, P.M.2
Mayor, F.3
Murga, C.4
-
34
-
-
0035947398
-
Changes in caveolin subtype protein expression in aging rat organs
-
Kawabe J.I., Grant B.S., Yamamoto M., Schwencke C., Okumura S., Ishikawa Y. Changes in caveolin subtype protein expression in aging rat organs. Mol. Cell. Endocrinol. 2001, 176:91-95.
-
(2001)
Mol. Cell. Endocrinol.
, vol.176
, pp. 91-95
-
-
Kawabe, J.I.1
Grant, B.S.2
Yamamoto, M.3
Schwencke, C.4
Okumura, S.5
Ishikawa, Y.6
-
35
-
-
0025805520
-
The human atrial trabecula: effects of calcium and temperature
-
Keon W.J., Labow R.S., Hendry P.J., Barry Y.A. The human atrial trabecula: effects of calcium and temperature. J. Mol. Cell. Cardiol. 1991, 23:357-364.
-
(1991)
J. Mol. Cell. Cardiol.
, vol.23
, pp. 357-364
-
-
Keon, W.J.1
Labow, R.S.2
Hendry, P.J.3
Barry, Y.A.4
-
36
-
-
33646034941
-
Acute PKCδ inhibition limits ischaemia-reperfusion injury in the aged rat heart: role of GSK-3β
-
Kostyak J.C., Hunter J.C., Korzick D.H. Acute PKCδ inhibition limits ischaemia-reperfusion injury in the aged rat heart: role of GSK-3β. Cardiovasc. Res. 2006, 70:325-334.
-
(2006)
Cardiovasc. Res.
, vol.70
, pp. 325-334
-
-
Kostyak, J.C.1
Hunter, J.C.2
Korzick, D.H.3
-
37
-
-
0026052721
-
Validation of human trabecular preparation for evaluation of inotropic substances
-
Labow R., Desjardins S., Keon W. Validation of human trabecular preparation for evaluation of inotropic substances. J. Pharmacol. Toxicol. Methods. 1991, 26:257-268.
-
(1991)
J. Pharmacol. Toxicol. Methods.
, vol.26
, pp. 257-268
-
-
Labow, R.1
Desjardins, S.2
Keon, W.3
-
38
-
-
33845664452
-
Reversal of mitochondrial defects before ischemia protects the aged heart
-
Lesnefsky E.J., He D., Moghaddas S., Hoppel C.L. Reversal of mitochondrial defects before ischemia protects the aged heart. FASEB J. 2006, 20:1543-1545.
-
(2006)
FASEB J.
, vol.20
, pp. 1543-1545
-
-
Lesnefsky, E.J.1
He, D.2
Moghaddas, S.3
Hoppel, C.L.4
-
39
-
-
9344264666
-
Attenuation of antioxidative capacity enhances reperfusion injury in aged rat myocardium after MI/R
-
Liu P., Xu B., Cavalieri T.A., Hock C.E. Attenuation of antioxidative capacity enhances reperfusion injury in aged rat myocardium after MI/R. Am. J. Physiol. Heart Circ. Physiol. 2004, 287:H2719-H2727.
-
(2004)
Am. J. Physiol. Heart Circ. Physiol.
, vol.287
-
-
Liu, P.1
Xu, B.2
Cavalieri, T.A.3
Hock, C.E.4
-
40
-
-
79954509823
-
Age-associated differences in the inhibition of mitochondrial permeability transition pore opening by cyclosporine A
-
Liu L., Zhu J., Brink P.R., Glass P.S., Rebecchi M.J. Age-associated differences in the inhibition of mitochondrial permeability transition pore opening by cyclosporine A. Acta Anaesthesiol. Scand. 2011, 55:622-630.
-
(2011)
Acta Anaesthesiol. Scand.
, vol.55
, pp. 622-630
-
-
Liu, L.1
Zhu, J.2
Brink, P.R.3
Glass, P.S.4
Rebecchi, M.J.5
-
42
-
-
0033774930
-
Tolerance to ischemia and hypoxia is reduced in aged human myocardium
-
Mariani J., Ou R., Bailey M., Rowland M., Nagley P., Rosenfeldt F., Pepe S. Tolerance to ischemia and hypoxia is reduced in aged human myocardium. J. Thoracic Cardiovasc. Surg. 2000, 120:660-667.
-
(2000)
J. Thoracic Cardiovasc. Surg.
, vol.120
, pp. 660-667
-
-
Mariani, J.1
Ou, R.2
Bailey, M.3
Rowland, M.4
Nagley, P.5
Rosenfeldt, F.6
Pepe, S.7
-
43
-
-
84881656587
-
Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics
-
Marzetti E., Csiszar A., Dutta D., Balagopal G., Calvani R., Leeuwenburgh C. Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics. Am. J. Physiol. Heart Circ. Physiol. 2013, 305:H459-H476.
-
(2013)
Am. J. Physiol. Heart Circ. Physiol.
, vol.305
-
-
Marzetti, E.1
Csiszar, A.2
Dutta, D.3
Balagopal, G.4
Calvani, R.5
Leeuwenburgh, C.6
-
44
-
-
33745234267
-
NADPH oxidases are in part responsible for increased cardiovascular superoxide production during aging
-
Oudot A., Martin C., Busseuil D., Vergely C., Demaison L., Rochette L. NADPH oxidases are in part responsible for increased cardiovascular superoxide production during aging. Free Radic. Biol. Med. 2006, 40:2214-2222.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 2214-2222
-
-
Oudot, A.1
Martin, C.2
Busseuil, D.3
Vergely, C.4
Demaison, L.5
Rochette, L.6
-
45
-
-
0034665065
-
ATP channels triggers the preconditioned state by generating free radicals
-
ATP channels triggers the preconditioned state by generating free radicals. Circ. Res. 2000, 87:460-466.
-
(2000)
Circ. Res.
, vol.87
, pp. 460-466
-
-
Pain, T.1
Yang, X.M.2
Critz, S.D.3
Yue, Y.4
Nakano, A.5
Liu, G.S.6
Heusch, G.7
Cohen, M.V.8
Downey, J.M.9
-
46
-
-
0038545554
-
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects
-
Peart J., Headrick J.P. Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects. Cardiovasc. Res. 2003, 58:589-601.
-
(2003)
Cardiovasc. Res.
, vol.58
, pp. 589-601
-
-
Peart, J.1
Headrick, J.P.2
-
48
-
-
33749349574
-
Cardioprotective effects of acute and chronic opioid treatment are mediated via different signaling pathways
-
Peart J.N., Gross G.J. Cardioprotective effects of acute and chronic opioid treatment are mediated via different signaling pathways. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H1746-H1753.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.291
-
-
Peart, J.N.1
Gross, G.J.2
-
49
-
-
34247619761
-
Impaired p38-MAPK/HSP27 signaling underlies aging-related failure in opioid-mediated cardioprotection
-
Peart J.N., Gross E.R., Headrick J.P., Gross G.J. Impaired p38-MAPK/HSP27 signaling underlies aging-related failure in opioid-mediated cardioprotection. J. Mol. Cell. Cardiol. 2007, 42:972-980.
-
(2007)
J. Mol. Cell. Cardiol.
, vol.42
, pp. 972-980
-
-
Peart, J.N.1
Gross, E.R.2
Headrick, J.P.3
Gross, G.J.4
-
50
-
-
84857244369
-
Opposing effects of age and calorie restriction on molecular determinants of myocardial ischemic tolerance
-
Peart J.N., See Hoe L., Pepe S., Johnson P., Headrick J.P. Opposing effects of age and calorie restriction on molecular determinants of myocardial ischemic tolerance. Rejuvenation Res. 2012, 15:59-70.
-
(2012)
Rejuvenation Res.
, vol.15
, pp. 59-70
-
-
Peart, J.N.1
See Hoe, L.2
Pepe, S.3
Johnson, P.4
Headrick, J.P.5
-
52
-
-
48249109117
-
Effect of cyclosporine on reperfusion injury in acute myocardial infarction
-
Piot C., Croisille P., Staat P., Thibault H., Rioufol G., Mewton N., Elbelghiti R., Cung T.T., Bonnefoy E., Angoulvant D., Macia C., Raczka F., Sportouch C., Gahide G., Finet G., André-Fouët X., Revel D., Kirkorian G., Monassier J.P., Derumeaux G., Ovize M. Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N. Engl. J. Med. 2008, 359:473-481.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 473-481
-
-
Piot, C.1
Croisille, P.2
Staat, P.3
Thibault, H.4
Rioufol, G.5
Mewton, N.6
Elbelghiti, R.7
Cung, T.T.8
Bonnefoy, E.9
Angoulvant, D.10
Macia, C.11
Raczka, F.12
Sportouch, C.13
Gahide, G.14
Finet, G.15
André-Fouët, X.16
Revel, D.17
Kirkorian, G.18
Monassier, J.P.19
Derumeaux, G.20
Ovize, M.21
more..
-
53
-
-
0344413625
-
Mechanisms of myocardial ischemic preconditioning are age related: PKC-epsilon does not play a requisite role in old rabbits
-
Przyklenk K., Li G., Simkhovich B.Z., Kloner R.A. Mechanisms of myocardial ischemic preconditioning are age related: PKC-epsilon does not play a requisite role in old rabbits. J. Appl. Physiol. 2003, 95:2563-2569.
-
(2003)
J. Appl. Physiol.
, vol.95
, pp. 2563-2569
-
-
Przyklenk, K.1
Li, G.2
Simkhovich, B.Z.3
Kloner, R.A.4
-
54
-
-
41149127345
-
Aging mouse hearts are refractory to infarct size reduction with post-conditioning
-
Przyklenk K., Maynard M., Darling C.E., Whittaker P. Aging mouse hearts are refractory to infarct size reduction with post-conditioning. J. Am. Coll. Cardiol. 2008, 51:1393-1398.
-
(2008)
J. Am. Coll. Cardiol.
, vol.51
, pp. 1393-1398
-
-
Przyklenk, K.1
Maynard, M.2
Darling, C.E.3
Whittaker, P.4
-
55
-
-
0032588766
-
Coenzyme Q10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: studies in rats and in human atrial tissue
-
Rosenfeldt F.L., Pepe S., Ou R., Mariani J.A., Rowland M.A., Nagley P., Linnane A.W. Coenzyme Q10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: studies in rats and in human atrial tissue. Biofactors 1999, 9:291-299.
-
(1999)
Biofactors
, vol.9
, pp. 291-299
-
-
Rosenfeldt, F.L.1
Pepe, S.2
Ou, R.3
Mariani, J.A.4
Rowland, M.A.5
Nagley, P.6
Linnane, A.W.7
-
56
-
-
0141674628
-
Protection of myocardium by cyclosporin A and insulin: in vitro simulated ischemia study in human myocardium
-
Schneider A., Ad N., Izhar U., Khaliulin I., Borman J.B., Schwalb H. Protection of myocardium by cyclosporin A and insulin: in vitro simulated ischemia study in human myocardium. Ann. Thorac. Surg. 2003, 76:1240-1245.
-
(2003)
Ann. Thorac. Surg.
, vol.76
, pp. 1240-1245
-
-
Schneider, A.1
Ad, N.2
Izhar, U.3
Khaliulin, I.4
Borman, J.B.5
Schwalb, H.6
-
57
-
-
0034795316
-
Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury
-
Schulman D., Latchman D.S., Yellon D.M. Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury. Am. J. Physiol. Heart Circ. Physiol. 2001, 281:H1630-H1636.
-
(2001)
Am. J. Physiol. Heart Circ. Physiol.
, vol.281
-
-
Schulman, D.1
Latchman, D.S.2
Yellon, D.M.3
-
58
-
-
84864622015
-
Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways
-
Shore D.E., Carr C.E., Ruvkun G. Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways. PLoS Genet. 2012, 8:e1002792.
-
(2012)
PLoS Genet.
, vol.8
-
-
Shore, D.E.1
Carr, C.E.2
Ruvkun, G.3
-
59
-
-
79551677684
-
Cells respond to mechanical stress by rapid disassembly of caveolae
-
Sinha B., Köster D., Ruez R., Gonnord P., Bastiani M., Abankwa D., Stan R.V., Butler-Browne G., Vedie B., Johannes L., Morone N., Parton R.G., Raposo G., Sens P., Lamaze C., Nassoy P. Cells respond to mechanical stress by rapid disassembly of caveolae. Cell. 2011, 144:402-413.
-
(2011)
Cell.
, vol.144
, pp. 402-413
-
-
Sinha, B.1
Köster, D.2
Ruez, R.3
Gonnord, P.4
Bastiani, M.5
Abankwa, D.6
Stan, R.V.7
Butler-Browne, G.8
Vedie, B.9
Johannes, L.10
Morone, N.11
Parton, R.G.12
Raposo, G.13
Sens, P.14
Lamaze, C.15
Nassoy, P.16
-
60
-
-
0027515127
-
Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling
-
Sutherland C., Leighton I.A., Cohen P. Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling. Biochem. J. 1993, 296:15-19.
-
(1993)
Biochem. J.
, vol.296
, pp. 15-19
-
-
Sutherland, C.1
Leighton, I.A.2
Cohen, P.3
-
61
-
-
0035208471
-
Differences in the expression of protein kinase C isoforms and its translocation after stimulation with phorbol ester between young-adult and middle-aged ventricular cardiomyocytes isolated from Fischer 344 rats
-
Takayama M., Ebihara Y., Tani M. Differences in the expression of protein kinase C isoforms and its translocation after stimulation with phorbol ester between young-adult and middle-aged ventricular cardiomyocytes isolated from Fischer 344 rats. Jpn. Circ. J. 2001, 65:1071-1076.
-
(2001)
Jpn. Circ. J.
, vol.65
, pp. 1071-1076
-
-
Takayama, M.1
Ebihara, Y.2
Tani, M.3
-
62
-
-
0034749272
-
ATP channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts
-
ATP channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts. Cardiovasc. Res. 2001, 49:56-68.
-
(2001)
Cardiovasc. Res.
, vol.49
, pp. 56-68
-
-
Tani, M.1
Honma, Y.2
Hasegawa, H.3
Tamaki, K.4
-
63
-
-
4043060632
-
Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway
-
Tsang A., Hausenloy D.J., Mocanu M.M., Yellon D.M. Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway. Circ. Res. 2004, 95:230-232.
-
(2004)
Circ. Res.
, vol.95
, pp. 230-232
-
-
Tsang, A.1
Hausenloy, D.J.2
Mocanu, M.M.3
Yellon, D.M.4
-
64
-
-
57149139006
-
Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning
-
Tsutsumi Y.M., Horikawa Y.T., Jennings M.M., Kidd M.W., Niesman I.R., Yokoyama U., Head B.P., Hagiwara Y., Ishikawa Y., Miyanohara A., Patel P.M., Insel P.A., Patel H.H., Roth D.M. Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning. Circulation 2008, 118:1979-1988.
-
(2008)
Circulation
, vol.118
, pp. 1979-1988
-
-
Tsutsumi, Y.M.1
Horikawa, Y.T.2
Jennings, M.M.3
Kidd, M.W.4
Niesman, I.R.5
Yokoyama, U.6
Head, B.P.7
Hagiwara, Y.8
Ishikawa, Y.9
Miyanohara, A.10
Patel, P.M.11
Insel, P.A.12
Patel, H.H.13
Roth, D.M.14
-
65
-
-
66149090230
-
Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemia
-
Whittaker R., Glassy M.S., Gude N., Sussman M.A., Gottlieb R.A., Glembotski C.C. Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemia. Am. J. Physiol. Heart Circ. Physiol. 2009, 296:H1633-H1642.
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.296
-
-
Whittaker, R.1
Glassy, M.S.2
Gude, N.3
Sussman, M.A.4
Gottlieb, R.A.5
Glembotski, C.C.6
-
66
-
-
13444274721
-
Age-related changes in ischemic tolerance in male and female mouse hearts
-
Willems L., Zatta A., Holmgren K., Ashton K.J., Headrick J.P. Age-related changes in ischemic tolerance in male and female mouse hearts. J. Mol. Cell. Cardiol. 2005, 38:245-256.
-
(2005)
J. Mol. Cell. Cardiol.
, vol.38
, pp. 245-256
-
-
Willems, L.1
Zatta, A.2
Holmgren, K.3
Ashton, K.J.4
Headrick, J.P.5
-
67
-
-
78751705241
-
EGF signaling comes of age: promotion of healthy aging in C. elegans
-
Yu S., Driscoll M. EGF signaling comes of age: promotion of healthy aging in C. elegans. Exp. Gerontol. 2011, 46:129-134.
-
(2011)
Exp. Gerontol.
, vol.46
, pp. 129-134
-
-
Yu, S.1
Driscoll, M.2
-
68
-
-
33748177384
-
Ischemic postconditioning protects remodeled myocardium via the PI3K-PKB/Akt reperfusion injury salvage kinase pathway
-
Zhu M., Feng J., Lucchinetti E., Fischer G., Xu L., Pedrazzini T., Schaub M.C., Zaugg M. Ischemic postconditioning protects remodeled myocardium via the PI3K-PKB/Akt reperfusion injury salvage kinase pathway. Cardiovasc. Res. 2006, 72:152-162.
-
(2006)
Cardiovasc. Res.
, vol.72
, pp. 152-162
-
-
Zhu, M.1
Feng, J.2
Lucchinetti, E.3
Fischer, G.4
Xu, L.5
Pedrazzini, T.6
Schaub, M.C.7
Zaugg, M.8
-
69
-
-
77953001152
-
Age-associated differences in activation of Akt/GSK-3β signaling pathways and inhibition of mitochondrial permeability transition pore opening in the rat heart
-
Zhu J., Rebecchi M.J., Tan M., Glass P.S., Brink P.R., Liu L. Age-associated differences in activation of Akt/GSK-3β signaling pathways and inhibition of mitochondrial permeability transition pore opening in the rat heart. J. Gerontol. A Biol. Sci. Med. Sci. 2010, 65:611-619.
-
(2010)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.65
, pp. 611-619
-
-
Zhu, J.1
Rebecchi, M.J.2
Tan, M.3
Glass, P.S.4
Brink, P.R.5
Liu, L.6
-
70
-
-
84875164497
-
Interactions of GSK-3β with mitochondrial permeability transition pore modulators during preconditioning: age-associated differences
-
Zhu J., Rebecchi M.J., Glass P.S., Brink P.R., Liu L. Interactions of GSK-3β with mitochondrial permeability transition pore modulators during preconditioning: age-associated differences. J. Gerontol. A Biol. Sci. Med. Sci. 2013, 68:395-403.
-
(2013)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.68
, pp. 395-403
-
-
Zhu, J.1
Rebecchi, M.J.2
Glass, P.S.3
Brink, P.R.4
Liu, L.5
|