Cardiac aging and insulin resistance: Could insulin/insulin-like growth factor (IGF) signaling be used as a therapeutic target?

Current Pharmaceutical Design

Volumn 19, Issue 32, 2013, Pages 5684-5694

  Boudina, Sihem ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Autophagy; Cardiac aging; Cardiac function; Fibrosis; Insulin signaling; Mitochondria; Reactive oxygen species

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; ADENINE NUCLEOTIDE TRANSLOCASE; AMINE OXIDASE (FLAVIN CONTAINING); CARNITINE PALMITOYLTRANSFERASE I; CITRATE SYNTHASE; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE; MATRIX METALLOPROTEINASE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN; XANTHINE OXIDASE;

AGING; AUTOPHAGY; CARDIAC AGING; CARDIOVASCULAR RISK; CARDIOVASCULAR SYSTEM; EXTRACELLULAR MATRIX; FATTY ACID OXIDATION; HEART; HEART FUNCTION; HEART MUSCLE; HEART PERFORMANCE; HUMAN; INSULIN RESISTANCE; MITOCHONDRION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

AGED; AGING; ANIMALS; CARDIOVASCULAR DISEASES; HUMANS; INSULIN; INSULIN RESISTANCE; MOLECULAR TARGETED THERAPY; RISK FACTORS; SIGNAL TRANSDUCTION; SOMATOMEDINS;

EID: 84884247290     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319320004     Document Type: Review

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