-
1
-
-
14644431156
-
Cardiac energetics and myocardial oxygen consumption
-
Williams and Wilkins. Baltimore, Maryland, USA
-
West, J.B. 1991. Cardiac energetics and myocardial oxygen consumption. Physiologic basis of medical practice. Williams and Wilkins. Baltimore, Maryland, USA. 250-260.
-
(1991)
Physiologic Basis of Medical Practice
, pp. 250-260
-
-
West, J.B.1
-
2
-
-
0003251788
-
Coronary blood flow and myocardial ischemia
-
W.B. Saunders Company. Philadelphia, Pennsylvania, USA.
-
Braunwald, E. 2001. Coronary blood flow and myocardial ischemia. Heart disease: a textbook of cardiovascular medicine. W.B. Saunders Company. Philadelphia, Pennsylvania, USA. 1161-1183.
-
(2001)
Heart Disease: A Textbook of Cardiovascular Medicine
, pp. 1161-1183
-
-
Braunwald, E.1
-
3
-
-
4444379952
-
Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart
-
Huang, Y., et al. 2004. Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart. FASEB J. 18:1138-1140.
-
(2004)
FASEB J.
, vol.18
, pp. 1138-1140
-
-
Huang, Y.1
-
4
-
-
0029439509
-
Oxidative stress: The paradox of aerobic life
-
Davies, KJ. 1995. Oxidative stress: the paradox of aerobic life. Biochem. Soc. Symp. 61:1-31.
-
(1995)
Biochem. Soc. Symp.
, vol.61
, pp. 1-31
-
-
Davies, K.J.1
-
5
-
-
0034814062
-
Cardiac energy metabolism: Models of cellular respiration
-
Jafri, M.S., Dudycha, S.J., and O'Rourke, B. 2001. Cardiac energy metabolism: models of cellular respiration. Annu. Rev. Biomed. Eng. 3:57-81.
-
(2001)
Annu. Rev. Biomed. Eng.
, vol.3
, pp. 57-81
-
-
Jafri, M.S.1
Dudycha, S.J.2
O'Rourke, B.3
-
6
-
-
0033588198
-
Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium
-
Ide, T., et al. 1999. Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. Circ. Res. 85:357-363.
-
(1999)
Circ. Res.
, vol.85
, pp. 357-363
-
-
Ide, T.1
-
7
-
-
0346788896
-
Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling
-
Miwa, S., and Brand, M.D. 2003. Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling. Biochem. Soc. Trans. 31:1300-1301.
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 1300-1301
-
-
Miwa, S.1
Brand, M.D.2
-
8
-
-
0141792570
-
Mitochondrial production of oxygen radical species and the role of Coenzyme Q as an antioxidant
-
Genova, M.L., et al. 2003. Mitochondrial production of oxygen radical species and the role of Coenzyme Q as an antioxidant. Exp. Biol. Med. (Maywood). 228:506-513.
-
(2003)
Exp. Biol. Med. (Maywood)
, vol.228
, pp. 506-513
-
-
Genova, M.L.1
-
9
-
-
0035080194
-
Cardiac toxicity of singlet oxygen: Implication in reperfusion injury
-
Toufektsian, M.C., Boucher, F.R., Tanguy, S., Morel, S., and de Leiris, J.G. 2001. Cardiac toxicity of singlet oxygen: implication in reperfusion injury. Antioxid. Redox. Signal. 3:63-69.
-
(2001)
Antioxid. Redox. Signal.
, vol.3
, pp. 63-69
-
-
Toufektsian, M.C.1
Boucher, F.R.2
Tanguy, S.3
Morel, S.4
De Leiris, J.G.5
-
10
-
-
0037032024
-
Angiotensin II stimulation of NAD(P)H oxidase activity: Upstream mediators
-
Seshiah, P.N., et al. 2002. Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators. Circ. Res. 91:406-413.
-
(2002)
Circ. Res.
, vol.91
, pp. 406-413
-
-
Seshiah, P.N.1
-
11
-
-
0032475865
-
Superoxide generation from endothelial nitricoxide synthase. A Ca2+/calmodulin-dependent and retrahydrobiopterin regularoiy process
-
Xia, Y., Tsai, A.L., Berka, V., and Zweier, J.L. 1998. Superoxide generation from endothelial nitricoxide synthase. A Ca2+/calmodulin-dependent and retrahydrobiopterin regularoiy process. J. Biol. Chem. 273:25804-25808.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25804-25808
-
-
Xia, Y.1
Tsai, A.L.2
Berka, V.3
Zweier, J.L.4
-
12
-
-
0032575598
-
Inducible nitric-oxide synthase generates Superoxide from the reductase domain
-
Xia, Y., Roman, L.J., Masters, B.S., and Zweier, J.L. 1998. Inducible nitric-oxide synthase generates Superoxide from the reductase domain. J. Biol. Chem. 273:22635-22639.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22635-22639
-
-
Xia, Y.1
Roman, L.J.2
Masters, B.S.3
Zweier, J.L.4
-
13
-
-
0034677947
-
NAD(P)H oxidase: Role in cardiovascular biology and disease
-
Griendling, K.K., Sorescu, D., and Ushio-Fukai, M. 2000. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ. Res. 86:494-501.
-
(2000)
Circ. Res.
, vol.86
, pp. 494-501
-
-
Griendling, K.K.1
Sorescu, D.2
Ushio-Fukai, M.3
-
14
-
-
0036545584
-
Role of oxidative stress in myocardial hypertrophy and failure
-
Sawyer, D.B., et al. 2002. Role of oxidative stress in myocardial hypertrophy and failure. J. Mol. Cell. Cantiol. 34:379-388.
-
(2002)
J. Mol. Cell. Cantiol.
, vol.34
, pp. 379-388
-
-
Sawyer, D.B.1
-
16
-
-
0037154308
-
Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice
-
Bendall, J.K., Cave, A.C., Heymes, C, Gall, N., and Shah, A.M. 2002. Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation. 105:293-296.
-
(2002)
Circulation
, vol.105
, pp. 293-296
-
-
Bendall, J.K.1
Cave, A.C.2
Heymes, C.3
Gall, N.4
Shah, A.M.5
-
17
-
-
0034681218
-
Possible mechanism(s) of arachidonic acid-induced intracellular acidosis in rat cardiac myocyres
-
Wu, M.L., Chan, C.C., and Su, M.J. 2000. Possible mechanism(s) of arachidonic acid-induced intracellular acidosis in rat cardiac myocyres. Circ. Res. 86:E55-E62.
-
(2000)
Circ. Res.
, vol.86
-
-
Wu, M.L.1
Chan, C.C.2
Su, M.J.3
-
18
-
-
1542358889
-
Involvement of reactive oxygen species in cardiotrophin-1-induced proliferation of cardiomyocytes differentiated from murine embryonic srem cells
-
Sauer, H., et al. 2004. Involvement of reactive oxygen species in cardiotrophin-1-induced proliferation of cardiomyocytes differentiated from murine embryonic srem cells. Exp. Cell Res. 294:313-324.
-
(2004)
Exp. Cell Res.
, vol.294
, pp. 313-324
-
-
Sauer, H.1
-
19
-
-
0037699981
-
Increased myocardial NADPH oxidase activity in human heart failure
-
Heymes, C., et al. 2003. Increased myocardial NADPH oxidase activity in human heart failure. J. Am. Coll Cardial. 41:2164-2171.
-
(2003)
J. Am. Coll Cardial.
, vol.41
, pp. 2164-2171
-
-
Heymes, C.1
-
20
-
-
0345258510
-
Regulation of hypertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes
-
Sabri, A., Hughie, H.H., and Lucchesi, P.A. 2003. Regulation of hypertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes. Antioxid. Redox Signal. 5:731-740.
-
(2003)
Antioxid. Redox Signal.
, vol.5
, pp. 731-740
-
-
Sabri, A.1
Hughie, H.H.2
Lucchesi, P.A.3
-
21
-
-
0035584857
-
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
-
Nordberg, J., and Arner, E.S. 2001. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol. Med. 31:1287-1312.
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 1287-1312
-
-
Nordberg, J.1
Arner, E.S.2
-
22
-
-
0009424743
-
Catalase: A tetrameric enzyme with four tightly bound molecules of NADPH
-
Kirkman, H.N., and Gaetani, G.F. 1984. Catalase: a tetrameric enzyme with four tightly bound molecules of NADPH. Proc. Natl. Acad. Sci. U. S. A. 81:4343-4347.
-
(1984)
Proc. Natl. Acad. Sci. U. S. A.
, vol.81
, pp. 4343-4347
-
-
Kirkman, H.N.1
Gaetani, G.F.2
-
23
-
-
0033553562
-
Mechanisms of protection of catalase by NADPH. Kinetics and stoichiometry
-
Kirkman, H.N., Rolfo, M., Ferraris, A.M., and Gaetani, G.F. 1999. Mechanisms of protection of catalase by NADPH. Kinetics and stoichiometry. J. Biol. Chem. 274:13908-13914.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13908-13914
-
-
Kirkman, H.N.1
Rolfo, M.2
Ferraris, A.M.3
Gaetani, G.F.4
-
24
-
-
0029187630
-
Diversity of glutathione peroxidases
-
Ursini, F., et al. 1995. Diversity of glutathione peroxidases. Methods Enzymol 252:38-53.
-
(1995)
Methods Enzymol.
, vol.252
, pp. 38-53
-
-
Ursini, F.1
-
25
-
-
0346687676
-
Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death
-
de Haan, J.B., et al. 2004. Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death. Free. Radic. Biol. Med. 36:53-64.
-
(2004)
Free. Radic. Biol. Med.
, vol.36
, pp. 53-64
-
-
De Haan, J.B.1
-
26
-
-
6344277918
-
Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function
-
Conrad, M., et al. 2004. Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function. Mol. Cell. Biol. 24:9414-9423.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 9414-9423
-
-
Conrad, M.1
-
27
-
-
0034656849
-
Reactive oxygen species, cell signaling, and cell injury
-
Hensley, K., Robinson, K.A., Gabbita, S.P., Salsman, S., and Floyd, R.A. 2000. Reactive oxygen species, cell signaling, and cell injury. Free Radic. Biol. Med. 28:1456-1462.
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 1456-1462
-
-
Hensley, K.1
Robinson, K.A.2
Gabbita, S.P.3
Salsman, S.4
Floyd, R.A.5
-
28
-
-
0034707049
-
G alpha(i) and G alpha(o) are target proteins of reactive oxygen species
-
Nishida, M., et al. 2000. G alpha(i) and G alpha(o) are target proteins of reactive oxygen species. Nature. 408:492-495.
-
(2000)
Nature
, vol.408
, pp. 492-495
-
-
Nishida, M.1
-
29
-
-
0142055950
-
Oxidative stress and cardiovascular injury: Part I: Basic mechanisms and in vivo monitoring of ROS
-
Griendling, K.K., and FitzGerald, G.A. 2003, Oxidative stress and cardiovascular injury: part I: basic mechanisms and in vivo monitoring of ROS. Circulation. 108:1912-1916.
-
(2003)
Circulation
, vol.108
, pp. 1912-1916
-
-
Griendling, K.K.1
FitzGerald, G.A.2
-
30
-
-
0037307184
-
Overexpression of tumor necrosis factor-alpha increases production of hydroxyl radical in murine myocardium
-
Machida, Y., et al. 2003. Overexpression of tumor necrosis factor-alpha increases production of hydroxyl radical in murine myocardium. Am. J. Physiol. Heart Circ. Physiol. 284:H449-H455.
-
(2003)
Am. J. Physiol. Heart Circ. Physiol.
, vol.284
-
-
Machida, Y.1
-
31
-
-
0037192342
-
Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy
-
Hirotani, S., et al. 2002. Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy. Circulation. 105:509-515.
-
(2002)
Circulation
, vol.105
, pp. 509-515
-
-
Hirotani, S.1
-
32
-
-
0034190272
-
Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis
-
Hsu, T.C, Young, M.R., Cmarik, J., and Colburn, N.H. 2000. Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis. Free Radic. Biol. Med. 28:1338-1348.
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 1338-1348
-
-
Hsu, T.C.1
Young, M.R.2
Cmarik, J.3
Colburn, N.H.4
-
33
-
-
0036511547
-
Reactive oxygen species and regulation of gene expression
-
Turpaev, K.T. 2002. Reactive oxygen species and regulation of gene expression. Biochemistry Mosc. 67:281-292.
-
(2002)
Biochemistry Mosc.
, vol.67
, pp. 281-292
-
-
Turpaev, K.T.1
-
34
-
-
0037189946
-
Proteasome inhibitors stimulate activator protein-1 pathway via reactive oxygen species production
-
Wu, H.M., Chi, K.H., and Lin, W.W. 2002. Proteasome inhibitors stimulate activator protein-1 pathway via reactive oxygen species production. FEBS Lett. 526:101-105.
-
(2002)
FEBS Lett.
, vol.526
, pp. 101-105
-
-
Wu, H.M.1
Chi, K.H.2
Lin, W.W.3
-
35
-
-
0031792920
-
Reactive oxygen species and oxidative DNA damage
-
Hemnani, T., and Parihar, M.S. 1998. Reactive oxygen species and oxidative DNA damage. Indian J. Physiol. Pharmacol. 42:440-452.
-
(1998)
Indian J. Physiol. Pharmacol.
, vol.42
, pp. 440-452
-
-
Hemnani, T.1
Parihar, M.S.2
-
36
-
-
0037453028
-
Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes
-
Suematsu, N., et al. 2003. Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes. Circulation. 107:1418-1423.
-
(2003)
Circulation
, vol.107
, pp. 1418-1423
-
-
Suematsu, N.1
-
37
-
-
0032189851
-
Lipid peroxidation and antioxidant enzymes in isoproterenol induced oxidative stress in rat tissues
-
Rathore, N., John, S., Kale, M., and Bhatnagar, D. 1998. Lipid peroxidation and antioxidant enzymes in isoproterenol induced oxidative stress in rat tissues. Pharmacol. Res. 38:297-303.
-
(1998)
Pharmacol. Res.
, vol.38
, pp. 297-303
-
-
Rathore, N.1
John, S.2
Kale, M.3
Bhatnagar, D.4
-
38
-
-
0028844279
-
Nature of the cardiomyocyte injury induced by lipid hydroperoxides
-
Thollon, C., Iliou, J.P., Cambarrat, C., Robin, F., and Vilaine, J.P. 1995. Nature of the cardiomyocyte injury induced by lipid hydroperoxides. Cardiovasc. Res. 30:648-655.
-
(1995)
Cardiovasc. Res.
, vol.30
, pp. 648-655
-
-
Thollon, C.1
Iliou, J.P.2
Cambarrat, C.3
Robin, F.4
Vilaine, J.P.5
-
39
-
-
0038544188
-
Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases
-
Rahman, I.2003. Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases. J. Biochem. Mol. Biol. 36:95-109.
-
(2003)
J. Biochem. Mol. Biol.
, vol.36
, pp. 95-109
-
-
Rahman, I.1
-
40
-
-
0037331390
-
H2O2-induced higher order chromatin degradation: A novel mechanism of oxidative genotoxicity
-
Konat, G.W. 2003. H2O2-induced higher order chromatin degradation: a novel mechanism of oxidative genotoxicity. J. Biosci. 28:57-60.
-
(2003)
J. Biosci.
, vol.28
, pp. 57-60
-
-
Konat, G.W.1
-
41
-
-
0034527742
-
Redox control of protein degradation
-
Lockwood, T.D. 2000. Redox control of protein degradation. Antioxid. Redox Signal. 2:851-878.
-
(2000)
Antioxid. Redox Signal.
, vol.2
, pp. 851-878
-
-
Lockwood, T.D.1
-
42
-
-
0346100345
-
Free radical-mediated oxidation of free amino acids and amino acid residues in proteins
-
Stadtman, E.R., and Levine, R.L. 2003. Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino Acids. 25:207-218.
-
(2003)
Amino Acids.
, vol.25
, pp. 207-218
-
-
Stadtman, E.R.1
Levine, R.L.2
-
43
-
-
0037198057
-
Paradigms and pitfalls of yeast longevity research
-
Sinclair, D.A. 2002. Paradigms and pitfalls of yeast longevity research. Mech. Ageing Dev. 123:857-867.
-
(2002)
Mech. Ageing Dev.
, vol.123
, pp. 857-867
-
-
Sinclair, D.A.1
-
44
-
-
0037469206
-
Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part III: Cellular and molecular clues to heart and arterial aging
-
Lakatta, E.G. 2003. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part III: cellular and molecular clues to heart and arterial aging. Circulation. 107:490-497.
-
(2003)
Circulation
, vol.107
, pp. 490-497
-
-
Lakatta, E.G.1
-
45
-
-
0034956656
-
Mouse models for mitochondrial disease
-
Wallace, D.C. 2001. Mouse models for mitochondrial disease, Am. J. Med. Genet. 106:71-93.
-
(2001)
Am. J. Med. Genet.
, vol.106
, pp. 71-93
-
-
Wallace, D.C.1
-
46
-
-
0344826529
-
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice
-
Scortegagna, M., et al. 2003. Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice. Nat. Genet. 35:331-340.
-
(2003)
Nat. Genet.
, vol.35
, pp. 331-340
-
-
Scortegagna, M.1
-
47
-
-
0035800882
-
Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy
-
Cesselli, D., et al. 2001. Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy. Circ. Res. 89:279-286.
-
(2001)
Circ. Res.
, vol.89
, pp. 279-286
-
-
Cesselli, D.1
-
48
-
-
0031761127
-
The nature of antioxidant defense mechanisms: A lesson from transgenic studies
-
Ho, Y.S., Magnenat, J.L., Gargano, M., and Cao, J. 1998. The nature of antioxidant defense mechanisms: a lesson from transgenic studies. Environ. Health Perspect. 106(Suppl. 5):1219-1228.
-
(1998)
Environ. Health Perspect.
, vol.106
, Issue.5 SUPPL.
, pp. 1219-1228
-
-
Ho, Y.S.1
Magnenat, J.L.2
Gargano, M.3
Cao, J.4
-
49
-
-
0029781555
-
The protective role of manganese Superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice
-
Yen, H.C., Oberley, T.D., Vichitbandha, S., Ho, Y.S., and St. Clair, D.K. 1996. The protective role of manganese Superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice. J. Clin. Invest. 98:1253-1260.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1253-1260
-
-
Yen, H.C.1
Oberley, T.D.2
Vichitbandha, S.3
Ho, Y.S.4
St. Clair, D.K.5
-
50
-
-
0010117025
-
Extracellular Superoxide dismutase transgene overexpression preserves postischemic myocardial function in isolated murine hearts
-
Chen, E.P., Bittner, H.B., Davis, R.D., Folz, R.J., and Van Trigt, P. 1996. Extracellular Superoxide dismutase transgene overexpression preserves postischemic myocardial function in isolated murine hearts. Circulation. 94:II412-II417.
-
(1996)
Circulation
, vol.94
-
-
Chen, E.P.1
Bittner, H.B.2
Davis, R.D.3
Folz, R.J.4
Van Trigt, P.5
-
51
-
-
0035057229
-
A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease
-
Pennathur, S., Wagner, J.D., Leeuwenburgh, C., Litwak, K.N., and Heinecke, J.W. 2001. A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease. J. Clin. Invest. 107:853-860.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 853-860
-
-
Pennathur, S.1
Wagner, J.D.2
Leeuwenburgh, C.3
Litwak, K.N.4
Heinecke, J.W.5
-
52
-
-
10744227294
-
Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma
-
Khatti, J.J., et al. 2004. Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma. Circulation. 109:520-525.
-
(2004)
Circulation
, vol.109
, pp. 520-525
-
-
Khatti, J.J.1
-
53
-
-
0026333959
-
Role of oxidized low density lipoprotein in atherogenesis
-
Witztum, J.L, and Steinberg, D. 1991. Role of oxidized low density lipoprotein in atherogenesis. J. Clin. Invest. 88:1785-1792.
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 1785-1792
-
-
Witztum, J.L.1
Steinberg, D.2
-
54
-
-
10544246489
-
Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability
-
Rajagopaian, S., Meng, X.P., Ramasamy, S., Harrison, D.G., and Galis, Z.S. 1996. Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. J. Clin. Invest. 98:2572-2579.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2572-2579
-
-
Rajagopaian, S.1
Meng, X.P.2
Ramasamy, S.3
Harrison, D.G.4
Galis, Z.S.5
-
55
-
-
0037176994
-
Postischemic recovery of contractile function is impaired in SOD2(+/-) but not SOD1(+/-) mouse hearts
-
Asimakis, G.K., Lick, S., and Patterson, C. 2002. Postischemic recovery of contractile function is impaired in SOD2(+/-) but not SOD1(+/-) mouse hearts. Circulation. 105:981-986.
-
(2002)
Circulation
, vol.105
, pp. 981-986
-
-
Asimakis, G.K.1
Lick, S.2
Patterson, C.3
-
56
-
-
0033967008
-
Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury
-
Yoshida, T., Maulik, N., Engelman, R.M., Ho, Y.S., and Das, D.K. 2000. Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury. Circ. Res. 86:264-269.
-
(2000)
Circ. Res.
, vol.86
, pp. 264-269
-
-
Yoshida, T.1
Maulik, N.2
Engelman, R.M.3
Ho, Y.S.4
Das, D.K.5
-
57
-
-
0031849502
-
Causative role of oxyradicals in myocardial stunning: A proven hypothesis. A brief review of the evidence demonstrating a major role of reactive oxygen species in several forms of postischemic dysfunction
-
Bolli, R. 1998. Causative role of oxyradicals in myocardial stunning: a proven hypothesis. A brief review of the evidence demonstrating a major role of reactive oxygen species in several forms of postischemic dysfunction. Basic Res. Cardiol. 93:156-162.
-
(1998)
Basic Res. Cardiol.
, vol.93
, pp. 156-162
-
-
Bolli, R.1
-
58
-
-
0032563386
-
Novel myofilament Ca2+-sensitizing property of xanthine oxidase inhibitors
-
Perez, N.G., Gao, W.D., and Marban, E. 1998. Novel myofilament Ca2+-sensitizing property of xanthine oxidase inhibitors. Circ. Res. 83:423-430.
-
(1998)
Circ. Res.
, vol.83
, pp. 423-430
-
-
Perez, N.G.1
Gao, W.D.2
Marban, E.3
-
59
-
-
0023219426
-
Evidence for a pathogenetic role of xanthine oxidase in the "stunned" myocardium
-
Charlat, M.I., et al. 1987. Evidence for a pathogenetic role of xanthine oxidase in the "stunned" myocardium. Am. J. Physiol. 252:H566-H577.
-
(1987)
Am. J. Physiol.
, vol.252
-
-
Charlat, M.I.1
-
60
-
-
0025266820
-
Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications
-
Pfeffer, M.A., and Braunwald, E. 1990. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circculation. 81:1161-1172.
-
(1990)
Circculation
, vol.81
, pp. 1161-1172
-
-
Pfeffer, M.A.1
Braunwald, E.2
-
61
-
-
0032573115
-
Activation of matrix metalloproteinases in the failing human heart: Breaking the tie that binds
-
Mann, D.L., and Spinale, F.G. 1998. Activation of matrix metalloproteinases in the failing human heart: breaking the tie that binds. Circulation. 98:1699-1702.
-
(1998)
Circulation
, vol.98
, pp. 1699-1702
-
-
Mann, D.L.1
Spinale, F.G.2
-
62
-
-
0033535974
-
Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis
-
von Harsdorf, R., Li, P.F., and Dietz, R. 1999. Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation. 99:2934-2941.
-
(1999)
Circulation
, vol.99
, pp. 2934-2941
-
-
Von Harsdorf, R.1
Li, P.F.2
Dietz, R.3
-
63
-
-
20844461656
-
Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: A new action for an old drug?
-
Engberding, N., et al. 2004. Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: a new action for an old drug? Circulation. 110:2175-2179.
-
(2004)
Circulation
, vol.110
, pp. 2175-2179
-
-
Engberding, N.1
-
64
-
-
0037905740
-
H(2)O(2) regulates cardiac myocyte phenotype via concentrationdependent activation of distinct kinase pathways
-
Kwon, S.H., Pimentel, D.R., Remondino, A., Sawyer, D.B., and Colucci, W.S. 2003. H(2)O(2) regulates cardiac myocyte phenotype via concentrationdependent activation of distinct kinase pathways. J. Mol. Cell. Cardiol. 35:615-621.
-
(2003)
J. Mol. Cell. Cardiol.
, vol.35
, pp. 615-621
-
-
Kwon, S.H.1
Pimentel, D.R.2
Remondino, A.3
Sawyer, D.B.4
Colucci, W.S.5
-
65
-
-
0036791698
-
Activation of NADPH oxidase during progression of cardiac hypertrophy to failure
-
Li, J.M., Gall, N.P., Grieve, D.J., Chen, M., and Shah, A.M. 2002. Activation of NADPH oxidase during progression of cardiac hypertrophy to failure. Hypertension. 40:477-484.
-
(2002)
Hypertension
, vol.40
, pp. 477-484
-
-
Li, J.M.1
Gall, N.P.2
Grieve, D.J.3
Chen, M.4
Shah, A.M.5
-
66
-
-
0037028866
-
The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model
-
Date, M.O., et al. 2002. The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model J. Am. Coll. Cardiol. 39:907-912.
-
(2002)
J. Am. Coll. Cardiol.
, vol.39
, pp. 907-912
-
-
Date, M.O.1
-
67
-
-
0036487320
-
Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy
-
Higuchi, Y., et al. 2002. Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy. J. Mol. Cell. Cardiol. 34:233-240.
-
(2002)
J. Mol. Cell. Cardiol.
, vol.34
, pp. 233-240
-
-
Higuchi, Y.1
-
68
-
-
0035980171
-
Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes
-
Pimentel, D.R., et al. 2001. Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circ. Res. 89:453-460.
-
(2001)
Circ. Res.
, vol.89
, pp. 453-460
-
-
Pimentel, D.R.1
-
69
-
-
0344665681
-
Regulation of calcineurin by oxidative stress
-
Ghosh, M.C., Wang, X., Li, S., and Klee, C. 2003. Regulation of calcineurin by oxidative stress. Methods Enzymol. 366:289-304.
-
(2003)
Methods Enzymol.
, vol.366
, pp. 289-304
-
-
Ghosh, M.C.1
Wang, X.2
Li, S.3
Klee, C.4
-
70
-
-
0031543318
-
Cancer-preventive selenocompounds induce a specific redox modification of cysteine-rich regions in Ca(2+)-dependent isoenzymes of protein kinase C
-
Gopalakrishna, R., Gundimeda, U., and Chen, Z.H. 1997. Cancer-preventive selenocompounds induce a specific redox modification of cysteine-rich regions in Ca(2+)-dependent isoenzymes of protein kinase C. Arch. Biochem. Biophys. 348:25-36.
-
(1997)
Arch. Biochem. Biophys.
, vol.348
, pp. 25-36
-
-
Gopalakrishna, R.1
Gundimeda, U.2
Chen, Z.H.3
-
71
-
-
0032566405
-
Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II
-
Nakamura, K., et al. 1998. Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II. Circulation. 98:794-799.
-
(1998)
Circulation
, vol.98
, pp. 794-799
-
-
Nakamura, K.1
-
72
-
-
0036323450
-
Simvastatin prevents angiotensin II-induced cardiac alteration and oxidative stress
-
Delbosc, S., Cristol, J.P., Descomps, B., Mimran, A., and Jover, B. 2002. Simvastatin prevents angiotensin II-induced cardiac alteration and oxidative stress. Hypertension. 40:142-147.
-
(2002)
Hypertension
, vol.40
, pp. 142-147
-
-
Delbosc, S.1
Cristol, J.P.2
Descomps, B.3
Mimran, A.4
Jover, B.5
-
73
-
-
0032563677
-
"Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium
-
Sugden, P.H., and Clerk, A. 1998. "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ. Res. 83:345-352.
-
(1998)
Circ. Res.
, vol.83
, pp. 345-352
-
-
Sugden, P.H.1
Clerk, A.2
-
74
-
-
0035186999
-
Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy
-
doi:10.1172/JCI200113350
-
Takemoto, M., et al. 2001. Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy. J. Clin. Invest. 108:1429-1437. doi:10.1172/JCI200113350.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1429-1437
-
-
Takemoto, M.1
-
75
-
-
0242266963
-
Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling
-
Izumiya, Y., et al. 2003. Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling. Circ. Res. 93:874-883.
-
(2003)
Circ. Res.
, vol.93
, pp. 874-883
-
-
Izumiya, Y.1
-
76
-
-
0032504189
-
Reactive oxygen, species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction
-
Gotoh, Y., and Cooper, J.A. 1998. Reactive oxygen, species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. J. Biol. Chem. 273:17477-17482.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17477-17482
-
-
Gotoh, Y.1
Cooper, J.A.2
-
77
-
-
9144231898
-
Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling
-
Yamaguchi, O., et al. 2003. Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling. Proc. Natl.. Acad. Sci. U. S. A. 100:15883-15888.
-
(2003)
Proc. Natl.. Acad. Sci. U. S. A.
, vol.100
, pp. 15883-15888
-
-
Yamaguchi, O.1
-
78
-
-
0033058929
-
Myocyte loss in chronic heart failure
-
Rayment, N.B., et al. 1999. Myocyte loss in chronic heart failure. J. Pathol. 188:213-219.
-
(1999)
J. Pathol.
, vol.188
, pp. 213-219
-
-
Rayment, N.B.1
-
79
-
-
3442884258
-
Molecular and cellular basis of the aetiology and management of diabetic cardiomyopathy: A short review
-
Adeghate, E. 2004. Molecular and cellular basis of the aetiology and management of diabetic cardiomyopathy: a short review. Mol. Cell. Biochem. 261:187-191.
-
(2004)
Mol. Cell. Biochem.
, vol.261
, pp. 187-191
-
-
Adeghate, E.1
-
80
-
-
0037423550
-
Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway
-
Remondino, A., et al. 2003. Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway. Circ. Res. 92:136-138.
-
(2003)
Circ. Res.
, vol.92
, pp. 136-138
-
-
Remondino, A.1
-
81
-
-
0031857290
-
Interaction of reactive oxygen species with ion transport mechanisms
-
Kourie, J.I. 1998. Interaction of reactive oxygen species with ion transport mechanisms. Am. J. Physiol. 275:C1-C24.
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Kourie, J.I.1
-
82
-
-
0030037436
-
The effect of oxygen free radicals on calcium current and dihydropyridine binding sites in guinea-pig ventricular myocytes
-
Guerra, L., Cerbai, E., Gessi, S., Borea, P.A., and Mugelli, A. 1996. The effect of oxygen free radicals on calcium current and dihydropyridine binding sites in guinea-pig ventricular myocytes. Br. J. Pharmacol. 118:1278-1284.
-
(1996)
Br. J. Pharmacol.
, vol.118
, pp. 1278-1284
-
-
Guerra, L.1
Cerbai, E.2
Gessi, S.3
Borea, P.A.4
Mugelli, A.5
-
83
-
-
0037628056
-
Free radical-induced protein modification and inhibition of Ca2+-ATPase of cardiac sarcoplasmic reticulum
-
Kaplan, P., Babusikova, E., Lehotsky, J., and Dobrota, D. 2003. Free radical-induced protein modification and inhibition of Ca2+-ATPase of cardiac sarcoplasmic reticulum. Mol. Cell. Biochem. 248:41-47.
-
(2003)
Mol. Cell. Biochem.
, vol.248
, pp. 41-47
-
-
Kaplan, P.1
Babusikova, E.2
Lehotsky, J.3
Dobrota, D.4
-
84
-
-
0026642949
-
Mechanism of the membrane depolarization induced by oxidative stress in guinea-pig ventricular cells
-
Nakaya, H., Takeda, Y., Tohse, N., and Kanno, M. 1992. Mechanism of the membrane depolarization induced by oxidative stress in guinea-pig ventricular cells. J. Mol. Cell. Cardiol. 24:523-534.
-
(1992)
J. Mol. Cell. Cardiol.
, vol.24
, pp. 523-534
-
-
Nakaya, H.1
Takeda, Y.2
Tohse, N.3
Kanno, M.4
-
85
-
-
33750740174
-
Free radicals enhance Na+/Ca2+ exchange in ventricular myocytes
-
Goldhaber, J.I. 1996. Free radicals enhance Na+/Ca2+ exchange in ventricular myocytes. Am. J. Physiol. 271:H823-H833.
-
(1996)
Am. J. Physiol.
, vol.271
-
-
Goldhaber, J.I.1
-
86
-
-
0037969707
-
ASK1 associates with troponin T and induces troponin T phosphorylation and contractile dysfunction in cardiomyocytes
-
He, X., et al. 2003. ASK1 associates with troponin T and induces troponin T phosphorylation and contractile dysfunction in cardiomyocytes. Am. J. Pathol. 163:243-251.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 243-251
-
-
He, X.1
-
87
-
-
0036182137
-
Lipotoxic diseases
-
Unger, R.H. 2002. Lipotoxic diseases. Annu. Rev. Med. 53:319-336.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
88
-
-
7744234747
-
Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart
-
Sharma, S., et al. 2004. Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart. FASEB J. 18:1692-1700.
-
(2004)
FASEB J.
, vol.18
, pp. 1692-1700
-
-
Sharma, S.1
-
89
-
-
0037417725
-
A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
-
Finck, B.N., et al. 2003. A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proc. Natl. Acad. Sci. U. S. A. 100:1226-1231.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 1226-1231
-
-
Finck, B.N.1
-
90
-
-
0027398455
-
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system
-
Balligand, J.L., Kelly, R.A., Marsden, P.A., Smith, T.W., and Michel, T. 1993. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc. Natl. Acad. Sci. U. S. A. 90:347-351.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 347-351
-
-
Balligand, J.L.1
Kelly, R.A.2
Marsden, P.A.3
Smith, T.W.4
Michel, T.5
-
91
-
-
9344267711
-
NO and superoxide: Opposite ends of the seesaw in cardiac contractility
-
Bonaventura, J., and Gow, A. 2004. NO and superoxide: opposite ends of the seesaw in cardiac contractility. Proc. Natl. Acad. Sci. U. S. A. 101:16403-16404.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 16403-16404
-
-
Bonaventura, J.1
Gow, A.2
-
92
-
-
8644244680
-
Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling
-
Khan, S.A., et al. 2004. Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling. Proc. Natl. Acad. Sci. U. S. A. 101:15944-15948.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15944-15948
-
-
Khan, S.A.1
-
93
-
-
2942675392
-
S-nitrosylation signaling in cell biology
-
Gaston, B.M., Carver, J., Doctor, A., and Palmer, L.A. 2003. S-nitrosylation signaling in cell biology. Mol. Interv. 3:253-263.
-
(2003)
Mol. Interv.
, vol.3
, pp. 253-263
-
-
Gaston, B.M.1
Carver, J.2
Doctor, A.3
Palmer, L.A.4
-
94
-
-
0033713239
-
cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: Potential role for nitrosylation
-
Paolocci, N., et al. 2000. cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation. Am. J. Physiol. Heart Circ. Physiol. 279:H1982-H1988.
-
(2000)
Am. J. Physiol. Heart Circ. Physiol.
, vol.279
-
-
Paolocci, N.1
-
95
-
-
8344233331
-
Nitroso-redox balance in the cardiovascular system
-
Hare, J.M. 2004. Nitroso-redox balance in the cardiovascular system. N. Engl. J. Med. 351:2112-2114.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2112-2114
-
-
Hare, J.M.1
-
96
-
-
0033900011
-
Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure
-
Ferdinandy, P., Danial, H., Ambrus, I., Rothery, R.A., and Schulz, R. 2000. Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure. Circ. Res. 87:241-247.
-
(2000)
Circ. Res.
, vol.87
, pp. 241-247
-
-
Ferdinandy, P.1
Danial, H.2
Ambrus, I.3
Rothery, R.A.4
Schulz, R.5
-
97
-
-
19644400578
-
Combination of isosorbide dinitrate and hydralazine in blacks with heart failure
-
Taylor, A.L., et al. 2004. Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. N. Engl. J. Med. 351:2049-2057.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2049-2057
-
-
Taylor, A.L.1
-
98
-
-
0141841614
-
Oxygen free radical release in human failing myocardium is associated wich increased activity of rac1-GTPase and represents a target for statin treatment
-
Maack, C., et al. 2003. Oxygen free radical release in human failing myocardium is associated wich increased activity of rac1-GTPase and represents a target for statin treatment. Circulation. 108:1567-1574.
-
(2003)
Circulation
, vol.108
, pp. 1567-1574
-
-
Maack, C.1
-
99
-
-
0035680903
-
The oxidative stress hypothesis of congestive heart failure: Radical thoughts
-
Mak, S., and Newton, G.E. 2001. The oxidative stress hypothesis of congestive heart failure: radical thoughts. Chest. 120:2035-2046.
-
(2001)
Chest
, vol.120
, pp. 2035-2046
-
-
Mak, S.1
Newton, G.E.2
-
100
-
-
0027369841
-
Chronic ethanol exposure increases lipopigment accumulation in human heart
-
Jaatinen, P., Saukko, P., and Hervonen, A. 1993. Chronic ethanol exposure increases lipopigment accumulation in human heart. Alcohol Alcohol. 28:559-569.
-
(1993)
Alcohol Alcohol
, vol.28
, pp. 559-569
-
-
Jaatinen, P.1
Saukko, P.2
Hervonen, A.3
-
101
-
-
0942265667
-
Redox modulation of the inotropic response to dobutamine is impaired in patients with heart failure
-
Mak, S., and Newton, G.E. 2004. Redox modulation of the inotropic response to dobutamine is impaired in patients with heart failure. Am. J. Physiol. Heart Circ. Physiol. 286:H789-H795.
-
(2004)
Am. J. Physiol. Heart Circ. Physiol.
, vol.286
-
-
Mak, S.1
Newton, G.E.2
-
102
-
-
0035856508
-
Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy
-
Cappola, T.P., et al. 2001. Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy. Circulation. 104:2407-2411.
-
(2001)
Circulation
, vol.104
, pp. 2407-2411
-
-
Cappola, T.P.1
-
103
-
-
0037024270
-
Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: Results from 2 placebo-controlled studies
-
Doehner, W., et al. 2002. Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies. Circulation. 105:2619-2624.
-
(2002)
Circulation
, vol.105
, pp. 2619-2624
-
-
Doehner, W.1
-
104
-
-
0035975943
-
Vitamin C inhibits endothelial cell apoptosis in congestive heart failure
-
Rossig, L., et al. 2001. Vitamin C inhibits endothelial cell apoptosis in congestive heart failure. Circulation. 104:2182-2187.
-
(2001)
Circulation
, vol.104
, pp. 2182-2187
-
-
Rossig, L.1
-
105
-
-
0035978763
-
Effect of carvedilol on survival in severe chronic heart failure
-
Packer, M., et al. 2001. Effect of carvedilol on survival in severe chronic heart failure. N. Engl. J. Med. 344:1651-1658.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1651-1658
-
-
Packer, M.1
-
106
-
-
0345157579
-
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease
-
Hennekens, C.H., et al. 1996. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N. Engl. J. Med. 334:1145-1149.
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1145-1149
-
-
Hennekens, C.H.1
-
107
-
-
0034688195
-
Vitamin E supplementation and cardiovascular events in high-risk patients
-
The Heart Outcomes Prevention Evaluation Study Investigators
-
Yusuf, S., Dagenais, G., Pogue, J., Bosch, J., and Sleight, P. 2000. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N. Engl. J. Med. 342:154-160.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 154-160
-
-
Yusuf, S.1
Dagenais, G.2
Pogue, J.3
Bosch, J.4
Sleight, P.5
-
108
-
-
0036834582
-
Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: Results of the HOPE study and MICRO-HOPE substudy
-
Lonn, E., et al. 2002. Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: results of the HOPE study and MICRO-HOPE substudy. Diabetes Care. 25:1919-1927.
-
(2002)
Diabetes Care
, vol.25
, pp. 1919-1927
-
-
Lonn, E.1
-
109
-
-
8844234928
-
Rationale, design and organisation of an efficacy and safety study of oxypurinol added to standard therapy in patients with NYHA class III - IV congestive heart failure
-
Freudenberger, R.S., et al. 2004. Rationale, design and organisation of an efficacy and safety study of oxypurinol added to standard therapy in patients with NYHA class III - IV congestive heart failure. Expert Opin. Investig. Drugs. 13:1509-1516.
-
(2004)
Expert Opin. Investig. Drugs.
, vol.13
, pp. 1509-1516
-
-
Freudenberger, R.S.1
-
110
-
-
0035253409
-
Angiogenesis: The role of the microenvironment in flipping the switch
-
Giordano, F.J., and Johnson, R.S. 2001. Angiogenesis: the role of the microenvironment in flipping the switch. Curr. Opin. Genet. Dev. 11:35-40.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 35-40
-
-
Giordano, F.J.1
Johnson, R.S.2
-
111
-
-
0032100732
-
HIF-1 alpha is required for solid tumor formation and embryonic vascularization
-
Ryan, H.E., Lo, J., and Johnson, R.S. 1998. HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J. 17:3005-3015.
-
(1998)
EMBO J.
, vol.17
, pp. 3005-3015
-
-
Ryan, H.E.1
Lo, J.2
Johnson, R.S.3
-
112
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet, P., et al. 1998. RoLe of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature. 394:485-490.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
-
113
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
-
Iyer, N.V., et al. 1998. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev. 12:149-162.
-
(1998)
Genes Dev.
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
-
114
-
-
0035812772
-
HIF-1, O(2), and the 3 PHDs: How animal cells signal hypoxia to the nucleus
-
Semenza, G.L. 2001. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell. 107:1-3.
-
(2001)
Cell
, vol.107
, pp. 1-3
-
-
Semenza, G.L.1
-
115
-
-
0036718539
-
Molecular basis of rhe VHL hereditary cancer syndrome
-
Kaelin, W.G., Jr. 2002. Molecular basis of rhe VHL hereditary cancer syndrome. Nat. Rev. Cancer. 2:673-682.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 673-682
-
-
Kaelin Jr., W.G.1
-
116
-
-
1642447143
-
A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression
-
Liu, Q., et al. 2004. A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression. Proc. Natl. Acad. Sci. U. S. A. 101:4302-4307.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 4302-4307
-
-
Liu, Q.1
-
117
-
-
0032504165
-
Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes
-
Cormier-Regard, S., Nguyen, S.V., and Claycomb, W.C. 1998. Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes. J. Biol. Chem. 273:17787-17792.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17787-17792
-
-
Cormier-Regard, S.1
Nguyen, S.V.2
Claycomb, W.C.3
-
118
-
-
0031041377
-
Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
-
Lee, P.J., et al. 1997. Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J. Biol. Chem. 272:5375-5381.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5375-5381
-
-
Lee, P.J.1
-
119
-
-
1342346637
-
O2-regulated gene expression: Transcriptional control of cardiorespiratory physiology by HIF-1
-
Semenza, G.L. 2004. O2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1. J. Appl. Physiol. 96:1173-1177; discussion 1170-1172.
-
(2004)
J. Appl. Physiol.
, vol.96
, pp. 1173-1177
-
-
Semenza, G.L.1
-
120
-
-
0034594876
-
Early expression of angiogenesis factors in acute myocardial ischemia and infarction
-
Lee, S.H., et al. 2000. Early expression of angiogenesis factors in acute myocardial ischemia and infarction. N. Engl. J. Med. 342:626-633.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 626-633
-
-
Lee, S.H.1
-
121
-
-
0038788826
-
Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): Role of cytoplasmic trapping of HIF-2alpha
-
Park, S.K., et al. 2003. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha. Mol. Cell. Biol. 23:4959-4971.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4959-4971
-
-
Park, S.K.1
-
122
-
-
14644426149
-
Malignant transformation of heart muscle in the absence of the von Hippel-Lindau protein
-
Lei, L., et al. 2004. Malignant transformation of heart muscle in the absence of the von Hippel-Lindau protein. Circulation. 110:III-45.
-
(2004)
Circulation
, vol.110
-
-
Lei, L.1
-
123
-
-
17444445711
-
Partial left ventriculectomy to treat end-stage heart disease
-
Batista, R.J., et al. 1997. Partial left ventriculectomy to treat end-stage heart disease. Ann. Thorac. Surg. 64:634-638.
-
(1997)
Ann. Thorac. Surg.
, vol.64
, pp. 634-638
-
-
Batista, R.J.1
-
124
-
-
1242316278
-
The potential role of ventricular compressive therapy
-
Gorman, R.C., Jackson, B.M., and Gorman, J.H. 2004. The potential role of ventricular compressive therapy. Surg. Clin. North Am. 84:45-59.
-
(2004)
Surg. Clin. North Am.
, vol.84
, pp. 45-59
-
-
Gorman, R.C.1
Jackson, B.M.2
Gorman, J.H.3
-
125
-
-
14344279280
-
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function
-
Giordano, F.J., et al. 2001. A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc. Natl. Acad. Sci. U. S. A. 98:5780-5785.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 5780-5785
-
-
Giordano, F.J.1
|