Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes

Journal of Lipid Research

Volumn 38, Issue 7, 1997, Pages 1384-1394

  De Vries, Johan E ^a   Vork, Michael M ^a   Roemen, Theo H M ^a   De Jong, Yvonne F ^a   Cleutjens, Jack P M ^a   Van Der Vusse, Ger J ^a   Van Bilsen, Marc ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Apoptosis; Cardiomyocytes; Fatty acid binding protein; Fatty acids; Lactate dehydrogenase

Indexed keywords

BOVINE SERUM ALBUMIN; DNA; FATTY ACID BINDING PROTEIN; LACTATE DEHYDROGENASE; MONOUNSATURATED FATTY ACID; SATURATED FATTY ACID; TRIACYLGLYCEROL;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; HEART MUSCLE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CARRIER PROTEINS; CELLS, CULTURED; CULTURE MEDIA; FATTY ACID-BINDING PROTEINS; FATTY ACIDS; FATTY ACIDS, MONOUNSATURATED; GLUCOSE; KINETICS; L-LACTATE DEHYDROGENASE; MYELIN P2 PROTEIN; MYOCARDIUM; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PHOSPHOLIPIDS; RATS; RATS, INBRED WKY; SERUM ALBUMIN, BOVINE; TRIGLYCERIDES;

EID: 0030760230     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Bishop, W. R., and R. M. Bell. 1988. Assembly of phospholipids into cellular membranes: biosynthesis, transmembrane movement and intracellular translocation. Annu. Rev. Cell. Biol. 4: 579-610.
2. Liscovitch, M., and L. C. Cantley. 1994. Lipid second messengers. Cell. 77: 329-334.
3. Van Bilsen, M., and G. J. Van der Vusse. 1995. Phospholipase-A2-dependent signalling in the heart. Cardiovasc. Res. 30: 518-529.
4. Neely, J. R., and H. E. Morgan. 1974. Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle. Annu. Rev. Physiol. 36: 413-459.
5. Van der Vusse, G. J., J. F. C. Glatz, H. C. Stam, and R. S. Reneman. 1992. Fatty acid homeostasis in the normoxic and ischemic heart. Physiol. Rev. 72: 881-940.
6. Rosenthal, M. D., and J. B. Warshaw. 1973. Interaction of fatty acid and glucose oxidation by cultured heart cells. J. Cell. Biol. 58: 332-339.
7. Rosenthal, M. D., and J. B. Warshaw. 1977. Fatty acid and glucose oxidation by cultured rat heart cells. J. Cell. Physiol. 93: 31-40.
8. Hexeberg, S., I. Hessevik, and E. Hexeberg. 1995. Intravenous lipid infusion results in myocardial lipid droplet accumulation combined with reduced myocardial performance in heparinized rabbits. Acta Physiol. Scand. 153: 159-168.
9. Moskowitz, M. S. 1907. Fatty acid-induced steatosis in monolayer cell cultures. In Lipid Metabolism in Tissue Culture Cells. G. H. Rothblat, and D. Kritchevsky, editors. The Wistar Institute Press, Philadelphia. Vol. 6. 49-59.
10. Rosenthal, M. D. 1981. Accumulation of neutral lipids by human skin fibroblasts: differential effects of saturated and unsaturated fatty acids. Lipids. 16: 173-182.
11. Buttke, T. M. 1984. Inhibition of lymphocyte proliferation by free fatty acids. I. Differential effects on mouse B and T lymphocytes. Immunology. 53: 235-242.
12. Zhang, C. L., V. Lyngmo, and A. Nordoy. 1992. The effects of saturated fatty acids on endothelial cells. Thromb. Res. 65: 65-75.
13. Doi, O., F. Doi, F. Schroeder, A. W. Alberts, and P. R. Vagelos. 1978. Manipulation of fatty acid composition of membrane phospholipid and its effects on cell growth in mouse LM cells. Biochim. Biophys. Acta. 509: 239-250.
14. Gordon, G. B. 1977. Saturated free fatty acid toxicity. II. Lipid accumulation, ultrastructural alterations, and toxicity in mammalian cells in culture. Exp. Mol. Pathol. 27: 262-276.
15. De Vries, J. E., T. H. M. Roemen, G. J. van der Vusse, and M. van Bilsen. 1995. Saturated, but not mono-unsaturated, fatty acids induce cell death in neonatal rat ventricular cardiomyocytes. Eur. J. Physiol. S430: R67.
16. Van der Vusse, G. J., T. H. M. Roemen, W. Flameng, and R. S. Reneman. 1983. Serum-myocardium gradients of non-esterified fatty acids in dogs, rat, and man. Biochim. Biophys. Acta. 752: 361-370.
17. Gavrieli, Y., Y. Sherman, and S. A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell. Biol. 119: 493-501.
18. Majno, G., and I. Joris. 1995. Apoptosis, oncosis, and necrosis: an overview of cell death. Am. J. Physiol. 146: 3-15.
19. Iwaki, K., V. P. Sukhatme, H. E. Shubeita, and K. R. Chien. 1990. Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response. J. Biol. Chem. 265: 13809-13817.
20. Van der Loop, F. T. L., G. J. J. M. Van Eys, G. Schaart, and F. C. S. Ramaekers. 1990. Titin expression as an early indication of heart and skeletal muscle differentiation in vitro. Developmental re-organization in relation to cytoskeletal constituents. J. Muscle Res. Cell Motil. 17: 1-14.
21. Clark, G., editor. 1981. Staining Procedures. 4th ed. Williams and Wilkins, Baltimore. 228-229.
22. Bergmeyer, H. U., and E. Bernt. 1974. UV assay for LDH with pyruvate and NADH. In Methods of Enzymatic Analysis. H. U. Bergmeyer, editor. 2nd ed. Vol. 2. Academic Press, Inc., New York. 574-579.
23. Vork, M. M., J. F. C. Glatz, D. A. M. Surtel, H. J. M. Knubben, and G. J. Van der Vusse. 1991. A sandwich enzyme-linked immuno-sorbent assay for the determination of rat heart fatty acid-binding protein using the streptavidin-biotin system. Application to tissue and effluent samples from normoxic rat heart perfusion. Biochim. Biophys. Acta. 1075: 199-205.
24. Coligan, J. E., A. M. Kruisbeek, D. H. Margulies, E. M. Shevarh, and W. Strober, editors. 1991. Current Protocols for Immunology. Greene Publishing Associates and Wiley-Interscience, New York. 3.17.7-3.17.8.
25. Van der Vusse, G. J., and T. H. Roemen. 1995. Gradient of fatty acids from blood plasma to skeletal muscle in dogs. J. Appl. Physiol. 78: 1839-1843.
26. Wallenstein, S., C. L. Zucker, and J. L. Fleiss. 1980. Some statistical methods useful in circulation research. Circ. Res. 47: 1-9.
27. Kerr, J. F. R., G. C. Gobe, C. M. Winterford, and B. V. Harmon. 1995. Anatomical methods in cell death. In Methods in Cell Biology. L. M. Schwartz, and B. A. Osborne, editors. Vol. 46. Academic Press, San Diego. 1-27.
28. Van der Laarse, A., J. C. Altona, and C. H. F. Bloys van Treslong. 1985. Anoxia in neonatal rat heart cell cultures. Basic Res. Cardiol. 80S1: 137-142.
29. Galli, G., and M. Pratelli. 1993. Activation of apoptosis by serum deprivation in a teratocarcinoma cell line: inhibition by L-acetylcarnitine. Exp. Cell. Res. 204: 54-60.
30. Sheng, Z., D. Pennica, W. I. Wood, and K. R. Chien. 1996. Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival. Development. 122: 419-428.
31. Ohlrogge, J. B., E. A. Emken, and R. M. Gulley. 1981. Human tissue lipids: occurrence of fatty acid isomers from dietary hydrogenated oils. J. Lipid Res. 22: 955-960.
32. Ratnayake, W. M., Z. Y. Chen, G. Pelletier, and D. Weber. 1994. Occurrence of 5c,8c,11c,15t-eicosatetraenoic acid and other unusual polyunsaturated fatty acids in rats fed partially hydrogenated canola oil. Lipids. 29: 707-714.
33. Lanser, A. C., E. A. Emken, and J. B. Ohlrogge. 1986. Oxidation of oleic and elaidic acids in rat and human heart homogenates. Biochem. Biophys. Acta. 875: 510-515.
34. Kinsella, J. E., G. Bruckner, J. Mai, and J. Shimp. 1981. Metabolism of trans fatty acids with emphasis on the effects of trans, trans-octadecadienoate on lipid composition, essential fatly acid, and prostaglandins: an overview. Am. J. Clin. Nutr. 34: 2307-2318.
35. Ross, P. D., and R. L. McCarl. 1984. Oxidation of carbohydrates and palmitate by intact cultured neonatal rat heart cells. Am. J. Physiol. 246: H389-H397.
36. Stubbs, C. D., and A. D. Smith. 1984. The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function. Biochim. Biophys. Acta. 779: 89-137.
37. Hoffmann, P., D. Richards, I. Heinroth-Hoffmann, P. Matthias, H. Wey, and M. Toraason. 1995. Arachidonic acid disrupts calcium dynamics in neonatal rat cardiac myocytes. Cardiovasc. Res. 30: 889-898.
38. Richieri, G. V., A. Anel, and A. M. Kleinfeld. 1993. Interactions of long-chain fatty acids and albumin: determination of free fatty acid levels using the fluorescent probe ADIFAB. Biochemistry. 32: 7574-7580.
39. Richieri, G. V., R. T. Ogata, and A. M. Kleinfeld. 1992. A fluorescently labeled intestinal fatty acid binding protein. J. Biol. Chem. 267: 23495-23501.
40. Rose, H., M. Conventz, Y. Fischer, E. Jungling, T. Hennecke, and H. Kammermeier. 1994. Long-chain fatty acid-binding to albumin: re-evaluation with directly measured concentrations. Biochim. Biophys. Acta. 1215: 321-326.
41. Cistola, D. P., J. A. Hamilton, D. Jackson, and D. M. Small. 1988. Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule. Biochemistry. 27: 1881-1888.
42. Hawley, H. P., and G. B. Gordon. 1976. The effects of long chain free fatty acids on human neutrophil function and structure. Lab. Invest. 34: 216-222.
43. Krown, K. A., T. M. Page, C. Nguyen, D. Zechner, V. Gutierrez, K. L. Comstock, C. C. Glembotski, P. J. E. Quintana, and S. A. Sabbadini. 1996. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. J. Clin. Invest. 98: 2854-2865.
44. Paumen, M. B., Y. Ishida, M. Muramatsu, M. Yamamoto, and T. Honjo. 1997. Inhibition of carnitine palmitoyl-transferase I augments sphingolipid synthesis and palmitate-induced apoptosis. J. Biol. Chem. 271: 3324-3329.
45. Lenaz, G., and G. P. Castelli. 1985. Membrane fluidity. Molecular basis and physiological significance. In Structure and Properties of Cell Membranes. G. Benga, editor. Vol. 1. CRC Press Inc., Boca Raton, FL. 93-136.
46. Innis, S. M., and M. T. Clandinin. 1981. Dynamic modulation of mitochondrial membrane physical properties and ATPase activity by diet lipid. Biochem. J. 198: 167-175.
47. Gould, R. J., B. H. Ginsberg, and A. A. Spector. 1982. Lipid effects on the binding properties of a reconstituted insulin receptor. J. Biol. Chem. 257: 477-484.
48. Singh, J. K., A. Dasgupta, T. Adayev, S. A. Shahmehdi, D. Hammond, and P. Banerjee. 1996. Apoptosis is associated with an increase in saturated fatty acid-containing phospholipids in the neuronal cell line, HN2-5. Biochim. Biophys. Acta. 1304: 171-178.
49. Surette, M. E., J. D. Winkler, A. N. Fonteh, and F. H. Chilton. 1996. Relationship between arachidonate-phospholipid remodeling and apoptosis. Biochemistry. 35: 9187-9196.
50. Cui, Z., M. Houweling, M. H. Chen, M. Record, H. Chap, D. E. Vance, and F. Tercé. 1996. A genetic defect in phosphatidylcholine biosynthesis triggers apoptosis in Chinese Hamster Ovary cells. J. Biol. Chem. 271: 14668-14671.