Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: Influence of age at onset, diabetes duration, and established and novel risk factors

Archives of Internal Medicine

Volumn 171, Issue 5, 2011, Pages 404-410

  Wannamethee, S Goya ^a   Shaper, A Gerald ^a   Whincup, Peter H ^b   Lennon, Lucy ^a   Sattar, Naveed ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; VON WILLEBRAND FACTOR;

ADULT; AGED; ALL CAUSE MORTALITY; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONFIDENCE INTERVAL; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE DURATION; GLUCOSE BLOOD LEVEL; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; KIDNEY DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; ONSET AGE; PRIORITY JOURNAL;

AGE OF ONSET; AGED; COMORBIDITY; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PROSPECTIVE STUDIES; RISK;

EID: 79952600167     PISSN: 00039926     EISSN: 15383679     Source Type: Journal    
DOI: 10.1001/archinternmed.2011.2     Document Type: Article

References (33)

1. Noto D, Cefalù AB, Barbagallo CM, et al. Hypertension and diabetes mellitus are associated with cardiovascular events in the elderly without cardiovascular disease: results of a 15-year follow-up in a Mediterranean population. Nutr Metab Cardiovasc Dis. 2009;19(5):321-326.
2. Rashidi A, Sehgal AR, Rahman M, O'Connor AS. The case for chronic kidney disease, diabetes mellitus, and myocardial infarction being equivalent risk factors for cardiovascular mortality in patients older than 65 years. Am J Cardiol. 2008;102(12):1668-1673.
3. Booth GL, Kapral MK, Fung K, Tu JV. Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study. Lancet. 2006;368(9529):29-36. (Pubitemid 43947203)
4. Lotufo PA, Gaziano JM, Chae CU, et al. Diabetes and all-cause and coronary heart disease mortality among US male physicians. Arch Intern Med. 2001;161(2):242-247. (Pubitemid 32102391)
5. Woodward M, Zhang X, Barzi F, et al; Asia Pacific Cohort Studies Collaboration. The effects of diabetes on the risks of major cardiovascular diseases and death in the Asia-Pacific region. Diabetes Care. 2003;26(2):360-366.
6. Emerging Risk Factors Collaboration; Sarwar N, Gao P, Kondapally S, et al. Fasting glucose concentration, diabetes mellitus, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010;375:2215-2222.
7. Bulugahapitiya U, Siyambalapitiya S, Sithole J, Idris I. Is diabetes a coronary risk equivalent? systematic review and meta-analysis. Diabet Med. 2009;26(2):142-148.
8. Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998;339(4):229-234. (Pubitemid 28350165)
9. Natarajan S, Liao Y, Sinha D, Cao G, McGee DL, Lipsitz SR. Sex differences in the effect of diabetes duration on coronary heart disease mortality. Arch Intern Med. 2005;165(4):430-435. (Pubitemid 40280199)
10. Juutilainen A, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Type 2 diabetes as a "coronary heart disease equivalent": an 18-year prospective population-based study in Finnish subjects. Diabetes Care. 2005;28(12):2901-2907.
11. Dagenais GR, St-Pierre A, Gilbert P, et al. Comparison of prognosis for men with type 2 diabetes mellitus and men with cardiovascular disease. CMAJ. 2009;180(1):40-47.
12. Evans JM, Wang J, Morris AD. Comparison of cardiovascular risk between patients with type 2 diabetes and those who had had a myocardial infarction: cross sectional and cohort studies. BMJ. 2002;324(7343):939-942. (Pubitemid 34429872)
13. Gu K, Cowie CC, Harris MI. Mortality in adults with and without diabetes in a national cohort of the US population, 1971-1993. Diabetes Care. 1998;21(7):1138-1145.
14. Barnett KN, McMurdo MET, Ogston SA, Morris AD, Evans JM. Mortality in people diagnosed with type 2 diabetes at an older age: a systematic review. Age Ageing. 2006;35(5):463-468. (Pubitemid 44295632)
15. Kolb H, Schneider B, Heinemann L, et al. Type 2 diabetes phenotype and progression is significantly different if diagnosed before versus after 65 years of age. J Diabetes Sci Technol. 2008;2(1):82-90.
16. Tan HH, McAlpine RR, James P, et al; DARTS/MEMO Collaboration. Diagnosis of type 2 diabetes at an older age: effect on mortality in men and women. Diabetes Care. 2004;27(12):2797-2799.
17. Smith NL, Barzilay JI, Kronmal R, Lumley T, Enquobahrie D, Psaty BM. Newonset diabetes and risk of all-cause and cardiovascular mortality: the Cardiovascular Health Study. Diabetes Care. 2006;29(9):2012-2017. (Pubitemid 44871179)
18. Kronmal RA, Barzilay JI, Smith NL, et al. Mortality in pharmacologically treated older adults with diabetes: the Cardiovascular Health Study, 1989-2001. PLoS Med. 2006;3(10):e400. doi:10.1371/journal.pmed.0030400.
19. Guzder RN, Gatling W, Mullee MA, Byrne CD. Early mortality from the time of diagnosis of type 2 diabetes: a 5-year prospective cohort study with a local age-and sex-matched comparison cohort. Diabet Med. 2007;24(10):1164-1167. (Pubitemid 47437880)
20. Wannamethee SG, Whincup PH, Shaper AG, Rumley A, Lennon L, Lowe GDO. Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men. J Thromb Haemost. 2009;7(10):1605-1611.
21. Sattar N, Wannamethee SG, Forouhi NG. Novel biochemical risk factors for type 2 diabetes: pathogenic insights or prediction possibilities? Diabetologia. 2008;51(6):926-940.
22. Shaper AG, Pocock SJ, Walker M, Cohen NM, Wale CJ, Thomson AG. British Regional Heart Study: cardiovascular risk factors in middle-aged men in 24 towns. BMJ (Clin Res Ed). 1981;283(6285):179-186. (Pubitemid 11071686)
23. Wannamethee SG, Lowe GDO, Whincup PH, Rumley A, Walker M, Lennon L. Physical activity and hemostatic and inflammatory variables in elderly men. Circulation. 2002;105(15):1785-1790. (Pubitemid 34408887)
24. Emberson JR, Whincup PH, Walker M, Thomas M, Alberti KGM. Biochemical measures in a population-based study: effect of fasting duration and time of day. Ann Clin Biochem. 2002;39(pt 5):493-501. (Pubitemid 34983445)
25. Wannamethee SG, Shaper AG, Whincup PH. Body fat distribution, body composition, and respiratory function in elderly men. Am J Clin Nutr. 2005;82(5):996-1003. (Pubitemid 43779756)
26. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-419. (Pubitemid 15018832)
27. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D; Modification of Diet in Renal Disease Study Group. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Ann Intern Med. 1999;130(6):461-470.
28. Walker M, Shaper AG, Lennon L, Whincup PH. Twenty year follow-up of a cohort study based in general practices in 24 British towns. J Public Health Med. 2000;22(4):479-485. (Pubitemid 32064892)
29. Rose G, Blackburn H, Gillum RF, Prineas RJ. Cardiovascular Survey Methods. 2nd ed. Geneva, Switzerland: World Health Organization; 1982.
30. Fox CS, Sullivan L, D'Agostino RB Sr, Wilson PW; Framingham Heart Study. The significant effect of diabetes duration on coronary heart disease mortality: the Framingham Heart Study. Diabetes Care. 2004;27(3):704-708. (Pubitemid 38280537)
31. Brun E, Nelson RG, Bennett PH, et al. Diabetes duration and cause-specific mortality in the Verona Diabetes Study. Diabetes Care. 2000;23(8):1119-1123. (Pubitemid 30616799)
32. WHO MONICA Project Principal Investigators. The World Health Organization MONICA Project (Monitoring Trends and Determinants in Cardiovascular Disease): a major international collaboration. J Clin Epidemiol. 1988;41(2):105-114 .
33. De Ferranti SD, Osganian SK. Epidemiology of paediatric metabolic syndrome and type 2 diabetes mellitus. Diab Vasc Dis Res. 2007;4(4):285-296.