Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart

Aging Cell

Volumn 13, Issue 3, 2014, Pages 529-539

  Dai, Dao Fu ^a   Karunadharma, Pabalu P ^a   Chiao, Ying A ^a   Basisty, Nathan ^a   Crispin, David ^a   Hsieh, Edward J ^a   Chen, Tony ^a   Gu, Haiwei ^a   Djukovic, Danijel ^a   Raftery, Daniel ^a   Beyer, Richard P ^a   Maccoss, Michael J ^a   Rabinovitch, Peter S ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Caloric restriction; Cardiac aging; Dynamics; Proteomics; Rapamycin

Indexed keywords

CITRIC ACID; FATTY ACID; PROTEIN; PROTEOME; RAPAMYCIN; DEUTERIUM; LEUCINE;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; CALORIC RESTRICTION; CITRIC ACID CYCLE; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; FATTY ACID METABOLISM; FEMALE; GLYCOLYSIS; HEART; HEART VENTRICLE HYPERTROPHY; MITOCHONDRION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEOMICS; QUANTITATIVE ANALYSIS; REJUVENATION; RESPIRATORY CHAIN; UBIQUITINATION; AGE; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE; CARDIOVASCULAR DISEASE; DRUG EFFECTS; HEART VENTRICLE REMODELING; METABOLISM; PHYSIOLOGY; RANDOMIZATION;

MURINAE;

AGE FACTORS; ANIMALS; CALORIC RESTRICTION; CARDIOVASCULAR DISEASES; DEUTERIUM; FEMALE; HEART; LEUCINE; MICE; MICE, INBRED C57BL; MYOCARDIUM; PROTEOME; RANDOM ALLOCATION; SIROLIMUS; VENTRICULAR REMODELING;

EID: 84901431879     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12203     Document Type: Article

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