Structure–activity relationships and mechanism of action of small molecule smoothened modulators discovered by high-throughput screening and rational design

Topics in Medicinal Chemistry

Volumn 16, Issue , 2015, Pages 43-108

  Manetti, Fabrizio ^a   Taddei, Maurizio ^a   Petricci, Elena ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

Hedgehog signaling; Hit to lead compound optimization; Small molecule; Smoothened antagonists and agonists; Structure activity relationships; Synthesis

Indexed keywords

EID: 84934285063     PISSN: 18622461     EISSN: 1862247X     Source Type: Book Series    
DOI: 10.1007/7355_2014_61     Document Type: Article

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