Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

Nature

Volumn 484, Issue 7392, 2012, Pages 125-129

  Firestone, Ari J ^a   Weinger, Joshua S ^b   Maldonado, Maria ^b   Barlan, Kari ^c   Langston, Lance D ^b   O'Donnell, Michael ^b   Gelfand, Vladimir I ^c   Kapoor, Tarun M ^b   Chen, James K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE INHIBITOR; ADENOSINE TRIPHOSPHATE; ALPHA TUBULIN; CILIOBREVIN; DNA; DYNEIN ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

CELL ORGANELLE; INHIBITOR; MOLECULAR ANALYSIS; MOTILITY; PERMEABILITY; PROTEIN; TIMESCALE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL ORGANELLE; CENTROMERE; CONTROLLED STUDY; CYTOPLASM; DNA REPLICATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; EUKARYOTIC FLAGELLUM; MELANOSOME; MEMBRANE FUSION; MEMBRANE TRANSPORT; MICROTUBULE; MITOSIS SPINDLE; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROTEIN TRANSPORT;

ANIMALS; CATTLE; CILIA; CYTOPLASM; CYTOPLASMIC DYNEINS; ENZYME INHIBITORS; HEDGEHOG PROTEINS; KINETOCHORES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MELANOSOMES; MICE; MICROTUBULES; MITOTIC SPINDLE APPARATUS; MOLECULAR WEIGHT; MOVEMENT; NIH 3T3 CELLS; PEROXISOMES; PROTEIN TRANSPORT; QUINAZOLINONES; SIGNAL TRANSDUCTION;

ERINACEIDAE;

EID: 84862814996     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10936     Document Type: Article

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