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Volumn 22, Issue 4, 2014, Pages 1429-1440

Design, synthesis, and evaluation of pyrrolo[2,1-f][1,2,4]triazine derivatives as novel hedgehog signaling pathway inhibitors

(9) Xin, Minhang a,b Zhang, Liandi b Tang, Feng b,c Tu, Chongxing b,c Wen, Jun b Zhao, Xinge b,c Liu, Zhaoyu b Cheng, Lingfei b,c Shen, Han b

a XI'AN JIAOTONG UNIVERSITY (China)

b Jiangsu Simcere Pharmaceutical RandD Co Ltd (China)

c Nanjing BioSciKin Co Ltd Small Molecule Drug Discovery Platform (China)

Author keywords

Hedgehog signaling pathway; Inhibitors; Novel; Pyrrolo 2,1 f 1,2,4 triazine

Indexed keywords

HEDGEHOG SIGNALING PATHWAY; INHIBITORS; NOVEL; PYRROLO[2,1-F][1,2,4]TRIAZINE;

ANIMALS; BENZAMIDES; DRUG DESIGN; HALF-LIFE; HEDGEHOG PROTEINS; INJECTIONS, INTRAVENOUS; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES;

EID: 84893729197 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.12.055 Document Type: Article

Times cited : (33)

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