Identification of vitamin D3-based hedgehog pathway inhibitors that incorporate an aromatic A-ring isostere

ACS Medicinal Chemistry Letters

Volumn 4, Issue 7, 2013, Pages 590-595

  Deberardinis, Albert M ^a   Banerjee, Upasana ^a   Hadden, M Kyle ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

basal cell carcinoma; Gli; hedgehog signaling pathway; medulloblastoma; vitamin D3

Indexed keywords

COLECALCIFEROL; COLECALCIFEROL DERIVATIVE; SONIC HEDGEHOG PROTEIN; VITAMIN D RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG DESIGN; DRUG DEVELOPMENT; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MEDULLOBLASTOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; UPREGULATION;

EID: 84880165607     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml400014t     Document Type: Article

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