Hedgehog-Gli signaling pathway inhibitors as anticancer agents

Journal of Medicinal Chemistry

Volumn 52, Issue 13, 2009, Pages 3829-3845

  Mahindroo, Neeraj ^a   Punchihewa, Chandanamali ^a   Fujii, Naoaki ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE 7 INHIBITOR; ALPHITOLIC ACID; AMINOPROLINE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZIMIDAZOLE DERIVATIVE; BETULIC ACID; BISAMIDE; COLUBRINIC ACID; CYCLOPAMINE; IPI 926; PHTHALAZINE DERIVATIVE; PHYSALIN B; PHYSALIN F; PYRAZOLINE DERIVATIVE; PYRIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; QUINAZOLINONE DERIVATIVE; QUINOXALINE DERIVATIVE; ROBOTNIKININ; SMOOTHENED PROTEIN INHIBITOR; SOLASODINE; SONIC HEDGEHOG PROTEIN; SONIC HEDGEHOG PROTEIN INHIBITOR; SULFONAMIDE; TOMATIDINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZERUMBONE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CELL; CANCER RESEARCH; CYTOTOXICITY; DRUG STRUCTURE; HUMAN; IC 50; MEDULLOBLASTOMA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; DRUG DISCOVERY; HEDGEHOG PROTEINS; HUMANS; NEOPLASMS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 67649983452     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm801420y     Document Type: Review

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