-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Y. Zhang, R. Proenca, M. Maffei, M. Barone, L. Leopold, and J.M. Friedman Positional cloning of the mouse obese gene and its human homologue Nature 372 1994 425 432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0028830080
-
The adipocyte: Storage depot or node on the energy information superhighway?
-
J.S. Flier The adipocyte: storage depot or node on the energy information superhighway? Cell 80 1995 15 18
-
(1995)
Cell
, vol.80
, pp. 15-18
-
-
Flier, J.S.1
-
3
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
J.M. Friedman, and J.L. Halaas Leptin and the regulation of body weight in mammals Nature 395 1998 763 770
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
4
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
F. Chehab, M. Lim, and R. Lu Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin Nat Genet 12 1996 318 320
-
(1996)
Nat Genet
, vol.12
, pp. 318-320
-
-
Chehab, F.1
Lim, M.2
Lu, R.3
-
5
-
-
0030250892
-
A role for leptin and its cognate receptor in hematopoiesis
-
B.D. Bennett, G.P. Solar, J.Q. Yuan, J. Mathias, G.R. Thomas, and W. Matthews A role for leptin and its cognate receptor in hematopoiesis Curr Biol 6 1996 1170 1180
-
(1996)
Curr Biol
, vol.6
, pp. 1170-1180
-
-
Bennett, B.D.1
Solar, G.P.2
Yuan, J.Q.3
Mathias, J.4
Thomas, G.R.5
Matthews, W.6
-
6
-
-
0032508682
-
Biological action of leptin as an angiogenic factor
-
M.R. Sierra-Honigmann, A.K. Nath, C. Murakami, G. García-Cardeña, A. Papapetropoulos, and W.C. Sessa Biological action of leptin as an angiogenic factor Science 281 1998 1683 1686
-
(1998)
Science
, vol.281
, pp. 1683-1686
-
-
Sierra-Honigmann, M.R.1
Nath, A.K.2
Murakami, C.3
García-Cardeña, G.4
Papapetropoulos, A.5
Sessa, W.C.6
-
7
-
-
84900843530
-
Regulatory T cells, leptin and angiogenesis
-
V. Pucino, V. De Rosa, C. Procaccini, and G. Matarese Regulatory T cells, leptin and angiogenesis Chem Immunol Allergy 99 2014 155 169
-
(2014)
Chem Immunol Allergy
, vol.99
, pp. 155-169
-
-
Pucino, V.1
De Rosa, V.2
Procaccini, C.3
Matarese, G.4
-
8
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
P. Ducy, M. Amling, S. Takeda, M. Priemel, A.F. Schilling, and F.T. Beil Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass Cell 100 2000 197 207
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.F.5
Beil, F.T.6
-
9
-
-
0032701466
-
Leptin stimulates glucose uptake in C2C12 muscle cells by activation of ERK2
-
L. Berti, and S. Gammeltoft Leptin stimulates glucose uptake in C2C12 muscle cells by activation of ERK2 Mol Cell Endocrinol 157 1999 121 130
-
(1999)
Mol Cell Endocrinol
, vol.157
, pp. 121-130
-
-
Berti, L.1
Gammeltoft, S.2
-
10
-
-
0032572722
-
Leptin modulates the T-cells immune response and reverses starvation-induced immunosuppression
-
G.M. Lord, G. Matarese, J.K. Howard, R.J. Baker, S.R. Bloom, and R.I. Lechler Leptin modulates the T-cells immune response and reverses starvation-induced immunosuppression Nature 394 1998 897 901
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
Baker, R.J.4
Bloom, S.R.5
Lechler, R.I.6
-
12
-
-
0032880663
-
Decreased CD4 + lymphocyte activation and increased interleukin-4 production in peripheral blood of rheumatoid arthritis patients after acute starvation
-
D.A. Fraser, J. Thoen, J.E. Reseland, O. Førre, and J. Kjeldsen-Kragh Decreased CD4 + lymphocyte activation and increased interleukin-4 production in peripheral blood of rheumatoid arthritis patients after acute starvation Clin Rheumatol 18 1999 394 401
-
(1999)
Clin Rheumatol
, vol.18
, pp. 394-401
-
-
Fraser, D.A.1
Thoen, J.2
Reseland, J.E.3
Førre, O.4
Kjeldsen-Kragh, J.5
-
13
-
-
2442618838
-
The weight of leptin in immunity
-
A. La Cava, and G. Matarese The weight of leptin in immunity Nat Rev Immunol 4 2004 371 379
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 371-379
-
-
La Cava, A.1
Matarese, G.2
-
15
-
-
77949493588
-
Leptin and adiponectin: From energy and metabolic dysbalance to inflammation and autoimmunity
-
A. Stofkova Leptin and adiponectin: from energy and metabolic dysbalance to inflammation and autoimmunity Endocr Regul 43 2009 157 168
-
(2009)
Endocr Regul
, vol.43
, pp. 157-168
-
-
Stofkova, A.1
-
16
-
-
80052409973
-
What's new in our understanding of the role of adipokines in rheumatic diseases?
-
R. Gómez, J. Conde, M. Scotece, J.J. Gómez-Reino, F. Lago, and O. Gualillo What's new in our understanding of the role of adipokines in rheumatic diseases? Nat Rev Rheumatol 7 2011 528 536
-
(2011)
Nat Rev Rheumatol
, vol.7
, pp. 528-536
-
-
Gómez, R.1
Conde, J.2
Scotece, M.3
Gómez-Reino, J.J.4
Lago, F.5
Gualillo, O.6
-
17
-
-
0036312494
-
Leptin accelerates autoimmune diabetes in female NOD mice
-
G. Matarese, V. Sanna, R.I. Lechler, N. Sarvetnick, S. Fontana, and S. Zappacosta Leptin accelerates autoimmune diabetes in female NOD mice Diabetes 51 2002 1356 1361
-
(2002)
Diabetes
, vol.51
, pp. 1356-1361
-
-
Matarese, G.1
Sanna, V.2
Lechler, R.I.3
Sarvetnick, N.4
Fontana, S.5
Zappacosta, S.6
-
18
-
-
0035873418
-
Requirement for leptin in the induction and progression of autoimmune encephalomyelitis
-
G. Matarese, A. Di Giacomo, V. Sanna, G.M. Lord, J.K. Howard, and A. Di Tuoro Requirement for leptin in the induction and progression of autoimmune encephalomyelitis J Immunol 166 2001 5909 5916
-
(2001)
J Immunol
, vol.166
, pp. 5909-5916
-
-
Matarese, G.1
Di Giacomo, A.2
Sanna, V.3
Lord, G.M.4
Howard, J.K.5
Di Tuoro, A.6
-
19
-
-
0018861450
-
Cell-mediated immunity in genetically obese C57BL/6J (ob/ob) mice
-
R.K. Chandra Cell-mediated immunity in genetically obese C57BL/6J (ob/ob) mice Am J Clin Nutr 33 1980 13 16
-
(1980)
Am J Clin Nutr
, vol.33
, pp. 13-16
-
-
Chandra, R.K.1
-
20
-
-
0018148843
-
Impairment of cell-mediated immunity in mutation diabetic mice (db/db)
-
M.A. Mandel, and A.A. Mahmoud Impairment of cell-mediated immunity in mutation diabetic mice (db/db) J Immunol 120 1978 1375 1377
-
(1978)
J Immunol
, vol.120
, pp. 1375-1377
-
-
Mandel, M.A.1
Mahmoud, A.A.2
-
21
-
-
0033304576
-
Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
-
M. Ozata, I.C. Ozdemir, and J. Licinio Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects J Clin Endocrinol Metab 84 1999 3686 3695
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 3686-3695
-
-
Ozata, M.1
Ozdemir, I.C.2
Licinio, J.3
-
22
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
I.S. Farooqi, G. Matarese, G.M. Lord, J.M. Keogh, E. Lawrence, and C. Agwu Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency J Clin Invest 110 2002 1093 1103
-
(2002)
J Clin Invest
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
Keogh, J.M.4
Lawrence, E.5
Agwu, C.6
-
23
-
-
84874480871
-
Selective capacity of metreleptin administration to reconstitute CD4 + T-cell number in females with acquired hypoleptinemia
-
G. Matarese, C. La Rocca, H.S. Moon, J.Y. Huh, M.T. Brinkoetter, and S. Chou Selective capacity of metreleptin administration to reconstitute CD4 + T-cell number in females with acquired hypoleptinemia Proc Natl Acad Sci U S A 110 2013 E818 E827
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. E818-E827
-
-
Matarese, G.1
La Rocca, C.2
Moon, H.S.3
Huh, J.Y.4
Brinkoetter, M.T.5
Chou, S.6
-
24
-
-
0036737730
-
Peripheral but not central leptin prevents the immunosuppression associated with hypoleptinemia in rats
-
Y. Zhang, J.T. Wilsey, C.D. Frase, M.M. Matheny, B.S. Bender, and S. Zolotukhin Peripheral but not central leptin prevents the immunosuppression associated with hypoleptinemia in rats J Endocrinol 174 2002 455 461
-
(2002)
J Endocrinol
, vol.174
, pp. 455-461
-
-
Zhang, Y.1
Wilsey, J.T.2
Frase, C.D.3
Matheny, M.M.4
Bender, B.S.5
Zolotukhin, S.6
-
25
-
-
33744812000
-
Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans
-
J.L. Chan, G. Matarese, G.K. Shetty, P. Raciti, I. Kelesidis, and D. Aufiero Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans Proc Natl Acad Sci U S A 103 2006 8481 8486
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 8481-8486
-
-
Chan, J.L.1
Matarese, G.2
Shetty, G.K.3
Raciti, P.4
Kelesidis, I.5
Aufiero, D.6
-
27
-
-
0037090316
-
Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia
-
P. Mancuso, A. Gottschalk, S.M. Phare, M. Peters-Golden, N.W. Lukacs, and G.B. Huffnagle Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia J Immunol 168 2002 4018 4024
-
(2002)
J Immunol
, vol.168
, pp. 4018-4024
-
-
Mancuso, P.1
Gottschalk, A.2
Phare, S.M.3
Peters-Golden, M.4
Lukacs, N.W.5
Huffnagle, G.B.6
-
28
-
-
4143146273
-
Leptin augments alveolar macrophage leukotriene synthesis by increasing phospholipase activity and enhancing group IVC iPLA2 (cPLA2γ) protein expression
-
P. Mancuso, C. Canetti, A. Gottschalk, P.K. Tithof, and M. Peters-Golden Leptin augments alveolar macrophage leukotriene synthesis by increasing phospholipase activity and enhancing group IVC iPLA2 (cPLA2γ) protein expression Am J Physiol 287 2004 L497 L502
-
(2004)
Am J Physiol
, vol.287
, pp. L497-L502
-
-
Mancuso, P.1
Canetti, C.2
Gottschalk, A.3
Tithof, P.K.4
Peters-Golden, M.5
-
29
-
-
0031965266
-
Leptin regulates proinflammatory immune responses
-
S. Loffreda, S.Q. Yang, H.Z. Lin, C.L. Karp, M.L. Brengman, and D.J. Wang Leptin regulates proinflammatory immune responses FASEB J 12 1998 57 65
-
(1998)
FASEB J
, vol.12
, pp. 57-65
-
-
Loffreda, S.1
Yang, S.Q.2
Lin, H.Z.3
Karp, C.L.4
Brengman, M.L.5
Wang, D.J.6
-
30
-
-
0029952911
-
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells
-
T. Gainsford, T.A. Willson, D. Metcalf, E. Handman, C. McFarlane, and A. Ng Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells Proc Natl Acad Sci U S A 93 1996 14564 14568
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14564-14568
-
-
Gainsford, T.1
Willson, T.A.2
Metcalf, D.3
Handman, E.4
McFarlane, C.5
Ng, A.6
-
31
-
-
0035887941
-
High-dose leptin activates human leukocytes via receptor expression on monocytes
-
H. Zarkesh-Esfahani, G. Pockley, R.A. Metcalfe, M. Bidlingmaier, Z. Wu, and A. Ajami High-dose leptin activates human leukocytes via receptor expression on monocytes J Immunol 167 2001 4593 4599
-
(2001)
J Immunol
, vol.167
, pp. 4593-4599
-
-
Zarkesh-Esfahani, H.1
Pockley, G.2
Metcalfe, R.A.3
Bidlingmaier, M.4
Wu, Z.5
Ajami, A.6
-
32
-
-
0035109175
-
Leptin: A potential regulator of polymorphonuclear neutrophil bactericidal action?
-
F. Caldefie-Chezet, A. Poulin, A. Tridon, B. Sion, and M.P. Vasson Leptin: a potential regulator of polymorphonuclear neutrophil bactericidal action? J Leukoc Biol 69 2001 414 418
-
(2001)
J Leukoc Biol
, vol.69
, pp. 414-418
-
-
Caldefie-Chezet, F.1
Poulin, A.2
Tridon, A.3
Sion, B.4
Vasson, M.P.5
-
33
-
-
0043198155
-
Leptin regulates functional capacities of polymorphonuclear neutrophils
-
F. Caldefie-Chezet, A. Poulin, and M.P. Vasson Leptin regulates functional capacities of polymorphonuclear neutrophils Free Radic Res 37 2003 809 814
-
(2003)
Free Radic Res
, vol.37
, pp. 809-814
-
-
Caldefie-Chezet, F.1
Poulin, A.2
Vasson, M.P.3
-
34
-
-
1642525689
-
Leptin indirectly activates human neutrophils via induction of TNF-α
-
H. Zarkesh-Esfahani, A.G. Pockley, Z. Wu, P.G. Hellewell, A.P. Weetman, and R.J. Ross Leptin indirectly activates human neutrophils via induction of TNF-α J Immunol 172 2004 1809 1814
-
(2004)
J Immunol
, vol.172
, pp. 1809-1814
-
-
Zarkesh-Esfahani, H.1
Pockley, A.G.2
Wu, Z.3
Hellewell, P.G.4
Weetman, A.P.5
Ross, R.J.6
-
35
-
-
0036431034
-
Impaired natural killer (NK) cell activity in leptin receptor deficient mice: Leptin as a critical regulator in NK cell development and activation
-
Z. Tian, R. Sun, H. Wei, and B. Gao Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation Biochem Biophys Res Commun 298 2002 297 302
-
(2002)
Biochem Biophys Res Commun
, vol.298
, pp. 297-302
-
-
Tian, Z.1
Sun, R.2
Wei, H.3
Gao, B.4
-
36
-
-
0037427522
-
Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines
-
Y. Zhao, R. Sun, L. You, C. Gao, and Z. Tian Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines Biochem Biophys Res Commun 300 2003 247 252
-
(2003)
Biochem Biophys Res Commun
, vol.300
, pp. 247-252
-
-
Zhao, Y.1
Sun, R.2
You, L.3
Gao, C.4
Tian, Z.5
-
37
-
-
33744946045
-
Leptin receptor expression and signaling in lymphocytes: Kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice
-
E. Papathanassoglou, K. El-Haschimi, X.C. Li, G. Matarese, T. Strom, and C. Mantzoros Leptin receptor expression and signaling in lymphocytes: kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice J Immunol 176 2006 7745 7752
-
(2006)
J Immunol
, vol.176
, pp. 7745-7752
-
-
Papathanassoglou, E.1
El-Haschimi, K.2
Li, X.C.3
Matarese, G.4
Strom, T.5
Mantzoros, C.6
-
39
-
-
0032741972
-
Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice
-
J.K. Howard, G.M. Lord, G. Matarese, S. Vendetti, M.A. Ghatei, and M.A. Ritter Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice J Clin Invest 104 1999 1051 1059
-
(1999)
J Clin Invest
, vol.104
, pp. 1051-1059
-
-
Howard, J.K.1
Lord, G.M.2
Matarese, G.3
Vendetti, S.4
Ghatei, M.A.5
Ritter, M.A.6
-
40
-
-
33847312289
-
A key role of leptin in the control of regulatory T cell proliferation
-
V. De Rosa, C. Procaccini, G. Calì, G. Pirozzi, S. Fontana, and S. Zappacosta A key role of leptin in the control of regulatory T cell proliferation Immunity 26 2007 241 255
-
(2007)
Immunity
, vol.26
, pp. 241-255
-
-
De Rosa, V.1
Procaccini, C.2
Calì, G.3
Pirozzi, G.4
Fontana, S.5
Zappacosta, S.6
-
41
-
-
78650188983
-
An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness
-
C. Procaccini, V. De Rosa, M. Galgani, L. Abanni, G. Calì, and A. Porcellini An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness Immunity 33 2010 929 941
-
(2010)
Immunity
, vol.33
, pp. 929-941
-
-
Procaccini, C.1
De Rosa, V.2
Galgani, M.3
Abanni, L.4
Calì, G.5
Porcellini, A.6
-
42
-
-
84866168094
-
Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4 + effector T cell responses
-
C. Procaccini, V. De Rosa, M. Galgani, F. Carbone, S. Cassano, and D. Greco Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4 + effector T cell responses J Immunol 189 2012 2941 2953
-
(2012)
J Immunol
, vol.189
, pp. 2941-2953
-
-
Procaccini, C.1
De Rosa, V.2
Galgani, M.3
Carbone, F.4
Cassano, S.5
Greco, D.6
-
44
-
-
84875464349
-
Cutting edge: Leptin-induced RORγt expression in CD4 + T cells promotes Th17 responses in systemic lupus erythematosus
-
Y. Yu, Y. Liu, F.D. Shi, H. Zou, G. Matarese, and A. La Cava Cutting edge: leptin-induced RORγt expression in CD4 + T cells promotes Th17 responses in systemic lupus erythematosus J Immunol 190 2013 3054 3058
-
(2013)
J Immunol
, vol.190
, pp. 3054-3058
-
-
Yu, Y.1
Liu, Y.2
Shi, F.D.3
Zou, H.4
Matarese, G.5
La Cava, A.6
-
45
-
-
84896318533
-
Revised diagnostic criteria of multiple sclerosis
-
R. Milo, and A. Miller Revised diagnostic criteria of multiple sclerosis Autoimmun Rev 13 2014 518 524
-
(2014)
Autoimmun Rev
, vol.13
, pp. 518-524
-
-
Milo, R.1
Miller, A.2
-
46
-
-
77649237783
-
Multiple sclerosis: Geoepidemiology, genetics and the environment
-
R. Milo, and E. Kahana Multiple sclerosis: geoepidemiology, genetics and the environment Autoimmun Rev 9 2010 A387 A394
-
(2010)
Autoimmun Rev
, vol.9
, pp. A387-A394
-
-
Milo, R.1
Kahana, E.2
-
48
-
-
72049092916
-
Body size and risk of MS in two cohorts of US women
-
K.L. Munger, T. Chitnis, and A. Ascherio Body size and risk of MS in two cohorts of US women Neurology 73 2009 1543 1550
-
(2009)
Neurology
, vol.73
, pp. 1543-1550
-
-
Munger, K.L.1
Chitnis, T.2
Ascherio, A.3
-
49
-
-
84866034486
-
High body index before age 20 is associated with increased risk for multiple sclerosis men and women
-
A.K. Hedström, T. Olsson, and L. Alfredsson High body index before age 20 is associated with increased risk for multiple sclerosis men and women Mult Scler J 18 2012 1334 1336
-
(2012)
Mult Scler J
, vol.18
, pp. 1334-1336
-
-
Hedström, A.K.1
Olsson, T.2
Alfredsson, L.3
-
50
-
-
84883415327
-
Childhood body mass index and multiple sclerosis risk: A long-term cohort study
-
K.L. Munger, J. Bentzen, B. Laursen, E. Stenager, N. Koch-henriksen, and T.I.A. Sørensen Childhood body mass index and multiple sclerosis risk: a long-term cohort study Mult Scler J 19 2013 1323 1329
-
(2013)
Mult Scler J
, vol.19
, pp. 1323-1329
-
-
Munger, K.L.1
Bentzen, J.2
Laursen, B.3
Stenager, E.4
Koch-Henriksen, N.5
Sørensen, T.I.A.6
-
51
-
-
84873666865
-
Childhood obesity and risk of pediatric multiple sclerosis and clinically isolated syndrome
-
A. Langer-gould, and B.E. Beaber Childhood obesity and risk of pediatric multiple sclerosis and clinically isolated syndrome Neurology 80 2013 548 552
-
(2013)
Neurology
, vol.80
, pp. 548-552
-
-
Langer-Gould, A.1
Beaber, B.E.2
-
52
-
-
84898743030
-
Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis
-
A.K. Hedström, I. Lima Bomfim, L. Barcellos, M. Gianfrancesco, C. Schaefer, and I. Kockum Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis Neurology 82 2014 865 872
-
(2014)
Neurology
, vol.82
, pp. 865-872
-
-
Hedström, A.K.1
Lima Bomfim, I.2
Barcellos, L.3
Gianfrancesco, M.4
Schaefer, C.5
Kockum, I.6
-
53
-
-
0034998907
-
Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males
-
G. Matarese, V. Sanna, A. Di Giacomo, G.M. Lord, J.K. Howard, and S.R. Bloom Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males Eur J Immunol 31 2001 1324 1332
-
(2001)
Eur J Immunol
, vol.31
, pp. 1324-1332
-
-
Matarese, G.1
Sanna, V.2
Di Giacomo, A.3
Lord, G.M.4
Howard, J.K.5
Bloom, S.R.6
-
54
-
-
0037241113
-
Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses
-
V. Sanna, A. Di Giacomo, A. La Cava, R.I. Lechler, S. Fontana, and S. Zappacosta Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses J Clin Invest 111 2003 241 250
-
(2003)
J Clin Invest
, vol.111
, pp. 241-250
-
-
Sanna, V.1
Di Giacomo, A.2
La Cava, A.3
Lechler, R.I.4
Fontana, S.5
Zappacosta, S.6
-
55
-
-
32444449415
-
Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis
-
V. De Rosa, C. Procaccini, A. La Cava, P. Chieffi, G.F. Nicoletti, and S. Fontana Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis J Clin Invest 116 2006 447 455
-
(2006)
J Clin Invest
, vol.116
, pp. 447-455
-
-
De Rosa, V.1
Procaccini, C.2
La Cava, A.3
Chieffi, P.4
Nicoletti, G.F.5
Fontana, S.6
-
56
-
-
78650667165
-
Leptin modulates the survival of autoreactive CD4 + T cells through the nutrient/energy-sensing mammalian target of rapamycin signaling pathway
-
M. Galgani, C. Procaccini, V. De Rosa, F. Carbone, P. Chieffi, and A. La Cava Leptin modulates the survival of autoreactive CD4 + T cells through the nutrient/energy-sensing mammalian target of rapamycin signaling pathway J Immunol 185 2010 7474 7479
-
(2010)
J Immunol
, vol.185
, pp. 7474-7479
-
-
Galgani, M.1
Procaccini, C.2
De Rosa, V.3
Carbone, F.4
Chieffi, P.5
La Cava, A.6
-
57
-
-
84904099188
-
Leukocyte infiltration into spinal cord of EAE mice is attenuated by removal of endothelial leptin signaling
-
S. Ouyang, H. Hsuchou, A.J. Kastin, P.K. Mishra, Y. Wang, and W. Pan Leukocyte infiltration into spinal cord of EAE mice is attenuated by removal of endothelial leptin signaling Brain Behav Immun 40 2014 61 73
-
(2014)
Brain Behav Immun
, vol.40
, pp. 61-73
-
-
Ouyang, S.1
Hsuchou, H.2
Kastin, A.J.3
Mishra, P.K.4
Wang, Y.5
Pan, W.6
-
58
-
-
36749018195
-
The effect of disease activity on leptin, leptin receptor and suppressor of cytokine signalling-3 expression in relapsing-remitting multiple sclerosis
-
G. Frisullo, M. Mirabella, F. Angelucci, M. Caggiula, R. Morosetti, and C. Sancricca The effect of disease activity on leptin, leptin receptor and suppressor of cytokine signalling-3 expression in relapsing-remitting multiple sclerosis J Neuroimmunol 192 2007 174 183
-
(2007)
J Neuroimmunol
, vol.192
, pp. 174-183
-
-
Frisullo, G.1
Mirabella, M.2
Angelucci, F.3
Caggiula, M.4
Morosetti, R.5
Sancricca, C.6
-
59
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
C. Lock, G. Hermans, R. Pedotti, A. Brendolan, E. Schadt, and H. Garren Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis Nat Med 8 2002 500 508
-
(2002)
Nat Med
, vol.8
, pp. 500-508
-
-
Lock, C.1
Hermans, G.2
Pedotti, R.3
Brendolan, A.4
Schadt, E.5
Garren, H.6
-
60
-
-
0038797814
-
Leptin as marker of multiple sclerosis activity in patients treated with interferon
-
A.P. Batocchi, M. Rotondi, M. Caggiula, G. Frisullo, F. Odoardi, and V. Nociti Leptin as marker of multiple sclerosis activity in patients treated with interferon- J Neuroimmunol 139 2003 150 154
-
(2003)
J Neuroimmunol
, vol.139
, pp. 150-154
-
-
Batocchi, A.P.1
Rotondi, M.2
Caggiula, M.3
Frisullo, G.4
Odoardi, F.5
Nociti, V.6
-
61
-
-
17044381726
-
Leptin increase in multiple sclerosis associates with reduced number of CD4 + CD25 + regulatory T cells
-
G. Matarese, P.B. Carrieri, A. La Cava, F. Perna, V. Sanna, and V. De Rosa Leptin increase in multiple sclerosis associates with reduced number of CD4 + CD25 + regulatory T cells Proc Natl Acad Sci U S A 102 2005 5150 5155
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5150-5155
-
-
Matarese, G.1
Carrieri, P.B.2
La Cava, A.3
Perna, F.4
Sanna, V.5
De Rosa, V.6
-
62
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
M. Feuerer, L. Herrero, D. Cipolletta, A. Naaz, J. Wong, and A. Nayer Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters Nat Med 8 2009 930 939
-
(2009)
Nat Med
, vol.8
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
-
63
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
S. Winer, Y. Chan, G. Paltser, D. Truong, H. Tsui, and J. Bahrami Normalization of obesity-associated insulin resistance through immunotherapy Nat Med 8 2009 921 929
-
(2009)
Nat Med
, vol.8
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
Truong, D.4
Tsui, H.5
Bahrami, J.6
-
64
-
-
84862986986
-
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
-
D. Cipolletta, M. Feuerer, A. Li, N. Kamei, J. Lee, and S.E. Shoelson PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells Nature 486 2012 549 553
-
(2012)
Nature
, vol.486
, pp. 549-553
-
-
Cipolletta, D.1
Feuerer, M.2
Li, A.3
Kamei, N.4
Lee, J.5
Shoelson, S.E.6
-
65
-
-
54249147709
-
Chronic calorie restriction attenuates experimental autoimmune encephalomyelitis
-
L. Piccio, J.L. Stark, and A.H. Cross Chronic calorie restriction attenuates experimental autoimmune encephalomyelitis J Leukoc Biol 8 2008 940 948
-
(2008)
J Leukoc Biol
, vol.8
, pp. 940-948
-
-
Piccio, L.1
Stark, J.L.2
Cross, A.H.3
-
66
-
-
75249094454
-
Calorie restriction and cancer prevention: Metabolic and molecular mechanisms
-
V.D. Longo, and L. Fontana Calorie restriction and cancer prevention: metabolic and molecular mechanisms Trends Pharmacol Sci 31 2010 89 98
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 89-98
-
-
Longo, V.D.1
Fontana, L.2
-
67
-
-
20144362640
-
Experimental allergic encephalomyelitis in male Lewis rats subjected to calorie restriction
-
A.I. Esquifino, P. Cano, V. Jimenez, R.A. Cutrera, and D.P. Cardinali Experimental allergic encephalomyelitis in male Lewis rats subjected to calorie restriction J Physiol Biochem 60 2004 245 252
-
(2004)
J Physiol Biochem
, vol.60
, pp. 245-252
-
-
Esquifino, A.I.1
Cano, P.2
Jimenez, V.3
Cutrera, R.A.4
Cardinali, D.P.5
-
68
-
-
33846927480
-
Immune response after experimental allergic encephalomyelitis in rats subjected to calorie restriction
-
A.I. Esquifino, P. Cano, V. Jimenez-Ortega, M.P. Fernandez-Mateos, and D.P. Cardinali Immune response after experimental allergic encephalomyelitis in rats subjected to calorie restriction J Neuroinflammation 4 2007 6
-
(2007)
J Neuroinflammation
, vol.4
, pp. 6
-
-
Esquifino, A.I.1
Cano, P.2
Jimenez-Ortega, V.3
Fernandez-Mateos, M.P.4
Cardinali, D.P.5
-
69
-
-
84886948570
-
Immunity, autoimmunity and inflammatory bowel disease
-
A. Cassinotti, P. Sarzi-Puttini, M. Fichera, Y. Shoenfeld, R. de Franchis, and S. Ardizzone Immunity, autoimmunity and inflammatory bowel disease Autoimmun Rev 13 2014 1 2
-
(2014)
Autoimmun Rev
, vol.13
, pp. 1-2
-
-
Cassinotti, A.1
Sarzi-Puttini, P.2
Fichera, M.3
Shoenfeld, Y.4
De Franchis, R.5
Ardizzone, S.6
-
71
-
-
84868207481
-
Ulcerative colitis
-
I. Ordás, L. Eckmann, M. Talamini, D.C. Baumgart, and W.J. Sandborn Ulcerative colitis Lancet 380 2012 1606 1619
-
(2012)
Lancet
, vol.380
, pp. 1606-1619
-
-
Ordás, I.1
Eckmann, L.2
Talamini, M.3
Baumgart, D.C.4
Sandborn, W.J.5
-
72
-
-
70949107842
-
Inflammatory bowel disease
-
C. Abraham, and J.H. Cho Inflammatory bowel disease N Engl J Med 361 2009 2066 2078
-
(2009)
N Engl J Med
, vol.361
, pp. 2066-2078
-
-
Abraham, C.1
Cho, J.H.2
-
74
-
-
84902656541
-
Body mass index and risk of autoimmune diseases: A study within the Danish National Birth Cohort
-
M.C. Harpsøe, S. Basit, M. Andersson, N.M. Nielsen, M. Frisch, and J. Wohlfahrt Body mass index and risk of autoimmune diseases: a study within the Danish National Birth Cohort Int J Epidemiol 2014 1 13
-
(2014)
Int J Epidemiol
, pp. 1-13
-
-
Harpsøe, M.C.1
Basit, S.2
Andersson, M.3
Nielsen, N.M.4
Frisch, M.5
Wohlfahrt, J.6
-
75
-
-
79953773560
-
Dietary intake and risk of developing inflammatory bowel disease: A systematic review of the literature
-
J.K. Hou, B. Abraham, and H. El-Serag Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature Am J Gastroenterol 106 2011 563 573
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 563-573
-
-
Hou, J.K.1
Abraham, B.2
El-Serag, H.3
-
76
-
-
78650807538
-
Puberty is delayed in male mice with dextran sodium sulfate colitis out of proportion to changes in food intake, body weight, and serum levels of leptin
-
M.D. Deboer, and Y. Li Puberty is delayed in male mice with dextran sodium sulfate colitis out of proportion to changes in food intake, body weight, and serum levels of leptin Pediatr Res 69 2011 34 39
-
(2011)
Pediatr Res
, vol.69
, pp. 34-39
-
-
Deboer, M.D.1
Li, Y.2
-
77
-
-
0031768795
-
Elevated plasma leptin concentrations in early stages of experimental intestinal inflammation in rats
-
M. Barbier, C. Cherbut, and A.C. Aube Elevated plasma leptin concentrations in early stages of experimental intestinal inflammation in rats Gut 43 1998 783 790
-
(1998)
Gut
, vol.43
, pp. 783-790
-
-
Barbier, M.1
Cherbut, C.2
Aube, A.C.3
-
78
-
-
0036080142
-
Leptin: A pivotal mediator of intestinal inflammation in mice
-
B. Siegmund, H.A. Lehr, and G. Fantuzzi Leptin: a pivotal mediator of intestinal inflammation in mice Gastroenterology 122 2002 2011 2025
-
(2002)
Gastroenterology
, vol.122
, pp. 2011-2025
-
-
Siegmund, B.1
Lehr, H.A.2
Fantuzzi, G.3
-
79
-
-
3042661014
-
Leptin receptor expression on T lymphocytes modulates chronic intestinal inflammation in mice
-
B. Siegmund, J.A. Sennello, J. Jones-Carson, and F. Gamboni- Robertson Leptin receptor expression on T lymphocytes modulates chronic intestinal inflammation in mice Gut 53 2004 965 972
-
(2004)
Gut
, vol.53
, pp. 965-972
-
-
Siegmund, B.1
Sennello, J.A.2
Jones-Carson, J.3
Gamboni- Robertson, F.4
-
80
-
-
34047130209
-
Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin deficient ob/ob mice
-
J.A. Senello, R. Fayad, M. Pini, M.E. Gove, and G. Fantuzzi Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin deficient ob/ob mice Cytokine 36 2006 261 266
-
(2006)
Cytokine
, vol.36
, pp. 261-266
-
-
Senello, J.A.1
Fayad, R.2
Pini, M.3
Gove, M.E.4
Fantuzzi, G.5
-
81
-
-
84885450444
-
The emerging role of leptin antagonist as potential therapeutic option for inflammatory bowel disease
-
U.P. Singh, N.P. Singh, H. Guan, B. Busbee, R.L. Price, and D.D. Taub The emerging role of leptin antagonist as potential therapeutic option for inflammatory bowel disease Int Rev Immunol 33 2014 23 33
-
(2014)
Int Rev Immunol
, vol.33
, pp. 23-33
-
-
Singh, U.P.1
Singh, N.P.2
Guan, H.3
Busbee, B.4
Price, R.L.5
Taub, D.D.6
-
82
-
-
0035191858
-
PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine
-
M. Buyse, F. Berlioz, S. Guilmeau, A. Tsocas, T. Voisin, and G. Péranzi PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine J Clin Invest 108 2001 1483 1494
-
(2001)
J Clin Invest
, vol.108
, pp. 1483-1494
-
-
Buyse, M.1
Berlioz, F.2
Guilmeau, S.3
Tsocas, A.4
Voisin, T.5
Péranzi, G.6
-
83
-
-
0037008676
-
Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE
-
M. Buyse, S.V. Sitaraman, X. Liu, A. Bado, and D. Merlin Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE J Biol Chem 277 2002 28182 28190
-
(2002)
J Biol Chem
, vol.277
, pp. 28182-28190
-
-
Buyse, M.1
Sitaraman, S.V.2
Liu, X.3
Bado, A.4
Merlin, D.5
-
84
-
-
0036209411
-
Crohn's disease clinical course and severity in obese patients
-
A. Blain, S. Cattan, L. Beaugerie, F. Carbonnel, J.P. Gendre, and J. Cosnes Crohn's disease clinical course and severity in obese patients Clin Nutr 21 2002 51 57
-
(2002)
Clin Nutr
, vol.21
, pp. 51-57
-
-
Blain, A.1
Cattan, S.2
Beaugerie, L.3
Carbonnel, F.4
Gendre, J.P.5
Cosnes, J.6
-
86
-
-
0036100751
-
Distribution of the long leptin receptor isoform in brush border, basolateral membrane, and cytoplasm of enterocytes
-
J. Barrenetxe, A.C. Villaro, L. Guembe, and I. Pascual Distribution of the long leptin receptor isoform in brush border, basolateral membrane, and cytoplasm of enterocytes Gut 50 2002 797 802
-
(2002)
Gut
, vol.50
, pp. 797-802
-
-
Barrenetxe, J.1
Villaro, A.C.2
Guembe, L.3
Pascual, I.4
-
87
-
-
3042704740
-
Colonic leptin: Source of a novel proinflammatory cytokine involved in IBD
-
S. Sitaraman, X. Liu, L. Charrier, and L.H. Gu Colonic leptin: Source of a novel proinflammatory cytokine involved in IBD FASEB J 18 2004 696 698
-
(2004)
FASEB J
, vol.18
, pp. 696-698
-
-
Sitaraman, S.1
Liu, X.2
Charrier, L.3
Gu, L.H.4
-
88
-
-
0344739789
-
Overexpression of leptin mRNA in mesenteric adipose tissue in inflammatory bowel diseases
-
M. Barbier, H. Vidal, P. Desreumaux, and L. Dubuquoy Overexpression of leptin mRNA in mesenteric adipose tissue in inflammatory bowel diseases Gastroenterol Clin Biol 27 2003 987 991
-
(2003)
Gastroenterol Clin Biol
, vol.27
, pp. 987-991
-
-
Barbier, M.1
Vidal, H.2
Desreumaux, P.3
Dubuquoy, L.4
-
89
-
-
2342564361
-
Leptin levels in the acute stage of ulcerative colitis
-
A. Tuzun, A. Uygun, and Z. Yesilova Leptin levels in the acute stage of ulcerative colitis J Gastroenterol Hepatol 19 2004 429 432
-
(2004)
J Gastroenterol Hepatol
, vol.19
, pp. 429-432
-
-
Tuzun, A.1
Uygun, A.2
Yesilova, Z.3
-
90
-
-
33645023150
-
Circulating levels of leptin, adiponectin, resistin, and ghrelin in inflammatory bowel disease
-
K. Karmiris, I.E. Koutroubakis, and C. Xidakis Circulating levels of leptin, adiponectin, resistin, and ghrelin in inflammatory bowel disease Inflamm Bowel Dis 12 2006 100 105
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 100-105
-
-
Karmiris, K.1
Koutroubakis, I.E.2
Xidakis, C.3
-
91
-
-
49549091196
-
Leptin, adiponectin, resistin, and ghrelin - Implications for inflammatory bowel disease
-
K. Karmiris, I.E. Koutroubakis, and E.A. Kouroumalis Leptin, adiponectin, resistin, and ghrelin - implications for inflammatory bowel disease Mol Nutr Food Res 52 2008 855 866
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 855-866
-
-
Karmiris, K.1
Koutroubakis, I.E.2
Kouroumalis, E.A.3
-
92
-
-
84870613773
-
Expression and release of leptin and proinflammatory cytokines in patients with ulcerative colitis and infectious diarrhea
-
G. Biesiada, J. Czepiel, and A. Ptak-Belowska Expression and release of leptin and proinflammatory cytokines in patients with ulcerative colitis and infectious diarrhea J Physiol Pharmacol 63 2012 471 481
-
(2012)
J Physiol Pharmacol
, vol.63
, pp. 471-481
-
-
Biesiada, G.1
Czepiel, J.2
Ptak-Belowska, A.3
-
94
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
M. Maffei, J. Halaas, and E. Ravussin Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects Nat Med 1 1995 1155 1161
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
-
95
-
-
0033946980
-
Photoperiodic versus metabolic signals as determinants of seasonal anestrus in the mare
-
B.P. Fitzgerald, and C.J. McManus Photoperiodic versus metabolic signals as determinants of seasonal anestrus in the mare Biol Reprod 63 2000 335 340
-
(2000)
Biol Reprod
, vol.63
, pp. 335-340
-
-
Fitzgerald, B.P.1
McManus, C.J.2
-
96
-
-
79955558382
-
Assessment of nutritional status and serum leptin in children with inflammatory bowel disease
-
B. Aurangzeb, S.T. Leach, D.A. Lemberg, and A.S. Day Assessment of nutritional status and serum leptin in children with inflammatory bowel disease J Pediatr Gastroenterol Nutr 52 2011 536 541
-
(2011)
J Pediatr Gastroenterol Nutr
, vol.52
, pp. 536-541
-
-
Aurangzeb, B.1
Leach, S.T.2
Lemberg, D.A.3
Day, A.S.4
-
97
-
-
84875874716
-
New learnings on the pathophysiology of RA from synovial biopsies
-
C. Pitzalis, S. Kelly, and F. Humby New learnings on the pathophysiology of RA from synovial biopsies Curr Opin Rheumatol 25 2013 334 344
-
(2013)
Curr Opin Rheumatol
, vol.25
, pp. 334-344
-
-
Pitzalis, C.1
Kelly, S.2
Humby, F.3
-
98
-
-
0036616573
-
The role of neuroendocrine system in the pathogenesis of rheumatic diseases
-
R. Imrich The role of neuroendocrine system in the pathogenesis of rheumatic diseases Endocr Regul 36 2002 95 106
-
(2002)
Endocr Regul
, vol.36
, pp. 95-106
-
-
Imrich, R.1
-
99
-
-
84900858569
-
Neuro-endocrine networks controlling immune system in health and disease
-
C. Procaccini, V. Pucino, V. De Rosa, G. Marone, and G. Matarese Neuro-endocrine networks controlling immune system in health and disease Front Immunol 5 2014 1 10
-
(2014)
Front Immunol
, vol.5
, pp. 1-10
-
-
Procaccini, C.1
Pucino, V.2
De Rosa, V.3
Marone, G.4
Matarese, G.5
-
100
-
-
0037080196
-
Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis
-
N. Busso, A. So, V. Chobaz-Peclat, C. Morard, E. Martinez-Soria, and D. Talabot-Ayer Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis J Immunol 168 2002 875 882
-
(2002)
J Immunol
, vol.168
, pp. 875-882
-
-
Busso, N.1
So, A.2
Chobaz-Peclat, V.3
Morard, C.4
Martinez-Soria, E.5
Talabot-Ayer, D.6
-
101
-
-
0037332229
-
Synergistic induction of nitric oxide synthase type II: In vitro effect of leptin and interferon-gamma in human chondrocytes and ATDC5 chondrogenic cells
-
M. Otero, J.J. Gomez Reino, and O. Gualillo Synergistic induction of nitric oxide synthase type II: in vitro effect of leptin and interferon-gamma in human chondrocytes and ATDC5 chondrogenic cells Arthritis Rheum 48 2003 404 409
-
(2003)
Arthritis Rheum
, vol.48
, pp. 404-409
-
-
Otero, M.1
Gomez Reino, J.J.2
Gualillo, O.3
-
102
-
-
5444259084
-
The regulation of chondrocyte function by proinflammatory mediators: Prostaglandins and nitric oxide
-
M.B. Goldring, and F. Berenbaum The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide Clin Orthop Relat Res 427 2004 37 46
-
(2004)
Clin Orthop Relat Res
, vol.427
, pp. 37-46
-
-
Goldring, M.B.1
Berenbaum, F.2
-
103
-
-
30344486078
-
Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: Synergistic effect of leptin with interleukin-1
-
M. Otero, R. Lago, F. Lago, J.J. Reino, and O. Gualillo Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1 Arthritis Res Ther 7 2005 581 591
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 581-591
-
-
Otero, M.1
Lago, R.2
Lago, F.3
Reino, J.J.4
Gualillo, O.5
-
105
-
-
0141762514
-
Leptin consumption in the inflamed joints of patients with rheumatoid arthritis
-
M. Bokarewa, D. Bokarew, O. Hultgren, and A. Tarkowski Leptin consumption in the inflamed joints of patients with rheumatoid arthritis Ann Rheum Dis 62 2003 952 956
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 952-956
-
-
Bokarewa, M.1
Bokarew, D.2
Hultgren, O.3
Tarkowski, A.4
-
106
-
-
79951660109
-
Elevated serum levels of resistin, leptin, and adiponectin are associated with C-reactive protein and also other clinical conditions in rheumatoid arthritis
-
T. Yoshino, N. Kusunoki, N. Tanaka, K. Kaneko, Y. Kusunoki, and H. Endo Elevated serum levels of resistin, leptin, and adiponectin are associated with C-reactive protein and also other clinical conditions in rheumatoid arthritis Intern Med 50 2011 269 275
-
(2011)
Intern Med
, vol.50
, pp. 269-275
-
-
Yoshino, T.1
Kusunoki, N.2
Tanaka, N.3
Kaneko, K.4
Kusunoki, Y.5
Endo, H.6
-
107
-
-
77951613182
-
Two-year follow-up of plasma leptin and other cytokines in patients with rheumatoid arthritis
-
D. Xibille-Friedmann, C. Bustos-Bahena, S. Hernandez-Gongora, R. Burgos-Vargas, and J.L. Montiel-Hernandez Two-year follow-up of plasma leptin and other cytokines in patients with rheumatoid arthritis Ann Rheum Dis 69 2010 930 931
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 930-931
-
-
Xibille-Friedmann, D.1
Bustos-Bahena, C.2
Hernandez-Gongora, S.3
Burgos-Vargas, R.4
Montiel-Hernandez, J.L.5
-
108
-
-
77951024909
-
Adiponectin and leptin serum concentrations in patients with rheumatoid arthritis
-
B. Targonska-Stepniak, M. Dryglewska, and M. Majdan Adiponectin and leptin serum concentrations in patients with rheumatoid arthritis Rheumatol Int 30 2010 731 737
-
(2010)
Rheumatol Int
, vol.30
, pp. 731-737
-
-
Targonska-Stepniak, B.1
Dryglewska, M.2
Majdan, M.3
-
109
-
-
84869489312
-
Analysis of adipose tissues and stromal vascular cells in a murine arthritis model
-
K. Hamaguchi, A. Itabashi, Y. Kuroe, M. Nakano, E. Fujimoto, and T. Kato Analysis of adipose tissues and stromal vascular cells in a murine arthritis model Metabolism 61 2012 1687 1695
-
(2012)
Metabolism
, vol.61
, pp. 1687-1695
-
-
Hamaguchi, K.1
Itabashi, A.2
Kuroe, Y.3
Nakano, M.4
Fujimoto, E.5
Kato, T.6
-
110
-
-
33747786726
-
Changes in plasma levels of fat derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis
-
M. Otero, R. Lago, R. Gomez, F. Lago, C. Dieguez, and J.J. Gómez-Reino Changes in plasma levels of fat derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis Ann Rheum Dis 65 2006 1198 1201
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 1198-1201
-
-
Otero, M.1
Lago, R.2
Gomez, R.3
Lago, F.4
Dieguez, C.5
Gómez-Reino, J.J.6
-
111
-
-
41049083323
-
Leptin serum levels in rheumatoid arthritis patients: Relation to disease duration and activity
-
B. Targonska-Stepniak, M. Majdan, and M. Dryglewska Leptin serum levels in rheumatoid arthritis patients: relation to disease duration and activity Rheumatol Int 28 2008 585 591
-
(2008)
Rheumatol Int
, vol.28
, pp. 585-591
-
-
Targonska-Stepniak, B.1
Majdan, M.2
Dryglewska, M.3
-
112
-
-
33846304699
-
Are plasma and synovial fluid leptin levels correlated with disease activity in rheumatoid arthritis?
-
S. Hizmetli, M. Kisa, N. Gokalp, and M.Z. Bakici Are plasma and synovial fluid leptin levels correlated with disease activity in rheumatoid arthritis? Rheumatol Int 27 2007 335 338
-
(2007)
Rheumatol Int
, vol.27
, pp. 335-338
-
-
Hizmetli, S.1
Kisa, M.2
Gokalp, N.3
Bakici, M.Z.4
-
113
-
-
33745728464
-
No change of serum levels of leptin and adiponectin during anti-tumour necrosis factor antibody treatment with adalimumab in patients with rheumatoid arthritis
-
P. Harle, P. Sarzi-Puttini, M. Cutolo, and R.H. Straub No change of serum levels of leptin and adiponectin during anti-tumour necrosis factor antibody treatment with adalimumab in patients with rheumatoid arthritis Ann Rheum Dis 65 2006 970 971
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 970-971
-
-
Harle, P.1
Sarzi-Puttini, P.2
Cutolo, M.3
Straub, R.H.4
-
114
-
-
23444462627
-
Markers of inflammation are negatively correlated with serum leptin in rheumatoid arthritis
-
C. Popa, M.G. Netea, T.R. Radstake, P.L. van Riel, P. Barrera, and J.W. van der Meer Markers of inflammation are negatively correlated with serum leptin in rheumatoid arthritis Ann Rheum Dis 64 2005 1195 1198
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 1195-1198
-
-
Popa, C.1
Netea, M.G.2
Radstake, T.R.3
Van Riel, P.L.4
Barrera, P.5
Van Der Meer, J.W.6
-
115
-
-
0033002314
-
Leptin serum levels are not correlated with disease activity in patients with rheumatoid arthritis
-
H.J. Anders, M. Rihl, A. Heufelder, O. Loch, and M. Schattenkirchner Leptin serum levels are not correlated with disease activity in patients with rheumatoid arthritis Metabolism 48 1999 745 748
-
(1999)
Metabolism
, vol.48
, pp. 745-748
-
-
Anders, H.J.1
Rihl, M.2
Heufelder, A.3
Loch, O.4
Schattenkirchner, M.5
-
116
-
-
67349188090
-
Serum and synovial fluid leptin levels and markers of inflammation in rheumatoid arthritis
-
A. Seven, S. Guzel, M. Aslan, and V. Hamuryudan Serum and synovial fluid leptin levels and markers of inflammation in rheumatoid arthritis Rheumatol Int 29 2009 743 747
-
(2009)
Rheumatol Int
, vol.29
, pp. 743-747
-
-
Seven, A.1
Guzel, S.2
Aslan, M.3
Hamuryudan, V.4
-
117
-
-
80051474980
-
Association of circulating adiponectin levels with progression of radiographic joint destruction in rheumatoid arthritis
-
J.T. Giles, D.M. van der Heijde, and J.M. Bathon Association of circulating adiponectin levels with progression of radiographic joint destruction in rheumatoid arthritis Ann Rheum Dis 70 2011 1562 1568
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1562-1568
-
-
Giles, J.T.1
Van Der Heijde, D.M.2
Bathon, J.M.3
-
118
-
-
69749093928
-
Adiponectin is a mediator of the inverse association of adiposity with radiographic damage in rheumatoid arthritis
-
J.T. Giles, M. Allison, C.O. Bingham III, W.M. Scott Jr.; and J.M. Bathon Adiponectin is a mediator of the inverse association of adiposity with radiographic damage in rheumatoid arthritis Arthritis Rheum 61 2009 1248 1256
-
(2009)
Arthritis Rheum
, vol.61
, pp. 1248-1256
-
-
Giles, J.T.1
Allison, M.2
Bingham, C.O.3
Scott, Jr.W.M.4
Bathon, J.M.5
-
119
-
-
33750283745
-
Serum leptin levels in rheumatoid arthritis and relationship with disease activity
-
R. Gunaydin, T. Kaya, A. Atay, N. Olmez, A. Hur, and M. Koseoglu Serum leptin levels in rheumatoid arthritis and relationship with disease activity South Med J 99 2006 1078 1083
-
(2006)
South Med J
, vol.99
, pp. 1078-1083
-
-
Gunaydin, R.1
Kaya, T.2
Atay, A.3
Olmez, N.4
Hur, A.5
Koseoglu, M.6
-
121
-
-
84877821946
-
Emerging and critical issues in the pathogenesis of lupus
-
M. Gatto, M. Zen, A. Ghirardello, S. Bettio, N. Bassi, and L. Iaccarino Emerging and critical issues in the pathogenesis of lupus Autoimmun Rev 12 2013 523 536
-
(2013)
Autoimmun Rev
, vol.12
, pp. 523-536
-
-
Gatto, M.1
Zen, M.2
Ghirardello, A.3
Bettio, S.4
Bassi, N.5
Iaccarino, L.6
-
122
-
-
0036954540
-
Triggers for antichromatin autoantibody production in SLE
-
J.W. Dieker, J. van der Vlag, and J.H. Berden Triggers for antichromatin autoantibody production in SLE Lupus 11 2002 856 864
-
(2002)
Lupus
, vol.11
, pp. 856-864
-
-
Dieker, J.W.1
Van Der Vlag, J.2
Berden, J.H.3
-
123
-
-
40049093765
-
Systemic lupus erythematosus
-
A. Rahman, and D.A. Isenberg Systemic lupus erythematosus N Engl J Med 358 2008 929 939
-
(2008)
N Engl J Med
, vol.358
, pp. 929-939
-
-
Rahman, A.1
Isenberg, D.A.2
-
124
-
-
67650644583
-
Adipocytokines in systemic lupus erythematosus: Relationship to inflammation, insulin resistance and coronary atherosclerosis
-
C.P. Chung, A.G. Long, J.F. Solus, Y.H. Rho, A. Oeser, and P. Raggi Adipocytokines in systemic lupus erythematosus: relationship to inflammation, insulin resistance and coronary atherosclerosis Lupus 18 2009 799 806
-
(2009)
Lupus
, vol.18
, pp. 799-806
-
-
Chung, C.P.1
Long, A.G.2
Solus, J.F.3
Rho, Y.H.4
Oeser, A.5
Raggi, P.6
-
125
-
-
33746772745
-
Altered levels of adipocytokines in association with insulin resistance in patients with systemic lupus erythematosus
-
K.E. Sada, Y. Yamasaki, M. Maruyama, H. Sugiyama, M. Yamamura, and Y. Maeshima Altered levels of adipocytokines in association with insulin resistance in patients with systemic lupus erythematosus J Rheumatol 33 2006 1545 1552
-
(2006)
J Rheumatol
, vol.33
, pp. 1545-1552
-
-
Sada, K.E.1
Yamasaki, Y.2
Maruyama, M.3
Sugiyama, H.4
Yamamura, M.5
Maeshima, Y.6
-
126
-
-
31644441277
-
Plasma, urine, and renal expression of adiponectin in human systemic lupus erythematosus
-
B.H. Rovin, H. Song, L.A. Hebert, T. Nadasdy, G. Nadasdy, and D.J. Birmingham Plasma, urine, and renal expression of adiponectin in human systemic lupus erythematosus Kidney Int 68 2005 1825 1833
-
(2005)
Kidney Int
, vol.68
, pp. 1825-1833
-
-
Rovin, B.H.1
Song, H.2
Hebert, L.A.3
Nadasdy, T.4
Nadasdy, G.5
Birmingham, D.J.6
-
127
-
-
34347389223
-
Leptin in autoimmunity: Many questions, some answers
-
G. Matarese, E.H. Leiter, and A. La Cava Leptin in autoimmunity: many questions, some answers Tissue Antigens 70 2007 87 95
-
(2007)
Tissue Antigens
, vol.70
, pp. 87-95
-
-
Matarese, G.1
Leiter, E.H.2
La Cava, A.3
-
128
-
-
80051471532
-
High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids
-
M. McMahon, B.J. Skaggs, L. Sahakian, J. Grossman, J. FitzGerald, and N. Ragavendra High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids Ann Rheum Dis 70 2011 1619 1624
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1619-1624
-
-
McMahon, M.1
Skaggs, B.J.2
Sahakian, L.3
Grossman, J.4
Fitzgerald, J.5
Ragavendra, N.6
-
129
-
-
0036036625
-
Serum leptin levels in women with systemic lupus erythematosus
-
A. Garcia-Gonzalez, L. Gonzalez-Lopez, I.C. Valera-Gonzalez, E.G. Cardona-Muñoz, M. Salazar-Paramo, and M. González-Ortiz Serum leptin levels in women with systemic lupus erythematosus Rheumatol Int 22 2002 138 141
-
(2002)
Rheumatol Int
, vol.22
, pp. 138-141
-
-
Garcia-Gonzalez, A.1
Gonzalez-Lopez, L.2
Valera-Gonzalez, I.C.3
Cardona-Muñoz, E.G.4
Salazar-Paramo, M.5
González-Ortiz, M.6
-
131
-
-
64849109200
-
Adipokines and systemic lupus erythematosus: Relationship with, metabolic syndrome and cardiovascular disease risk factors
-
M. Vadacca, D. Margiotta, A. Rigon, F. Cacciapaglia, G. Coppolino, and A. Amoroso Adipokines and systemic lupus erythematosus: relationship with, metabolic syndrome and cardiovascular disease risk factors J Rheumatol 36 2009 295 297
-
(2009)
J Rheumatol
, vol.36
, pp. 295-297
-
-
Vadacca, M.1
Margiotta, D.2
Rigon, A.3
Cacciapaglia, F.4
Coppolino, G.5
Amoroso, A.6
-
132
-
-
84896932139
-
Association between leptin and systemic lupus erythematosus
-
W.D. Xu, M. Zhang, Y.J. Zhang, S.S. Liu, H.F. Pan, and D.Q. Ye Association between leptin and systemic lupus erythematosus Rheumatol Int 34 2014 559 563
-
(2014)
Rheumatol Int
, vol.34
, pp. 559-563
-
-
Xu, W.D.1
Zhang, M.2
Zhang, Y.J.3
Liu, S.S.4
Pan, H.F.5
Ye, D.Q.6
-
133
-
-
84863135746
-
Fasting-induced hypoletinemia expands functional regulatory T cells in systemic lupus erythematosus
-
Y. Liu, Y. Yu, G. Matarese, and A. La Cava Fasting-induced hypoletinemia expands functional regulatory T cells in systemic lupus erythematosus J Immunol 188 2013 2070 2073
-
(2013)
J Immunol
, vol.188
, pp. 2070-2073
-
-
Liu, Y.1
Yu, Y.2
Matarese, G.3
La Cava, A.4
-
134
-
-
84893362864
-
Deficient leptin signalling ameliorates systemic lupus erythematosus lesions in MRL/Mp - Faslpr mice
-
Y. Fujita, T. Fujii, T. Mimori, T. Sato, T. Nakamura, and H. Iwao Deficient leptin signalling ameliorates systemic lupus erythematosus lesions in MRL/Mp - Faslpr mice J Immunol 192 2014 979 984
-
(2014)
J Immunol
, vol.192
, pp. 979-984
-
-
Fujita, Y.1
Fujii, T.2
Mimori, T.3
Sato, T.4
Nakamura, T.5
Iwao, H.6
-
135
-
-
84888030086
-
Leptin promotes lupus T-cell autoimmunity
-
G. Amarilyo, N. Iikuni, F.D. Shi, A. Liu, G. Matarese, and A. La Cava Leptin promotes lupus T-cell autoimmunity Clin Immunol 149 2013 530 533
-
(2013)
Clin Immunol
, vol.149
, pp. 530-533
-
-
Amarilyo, G.1
Iikuni, N.2
Shi, F.D.3
Liu, A.4
Matarese, G.5
La Cava, A.6
-
136
-
-
84896491806
-
The many faces of diabetes: A disease with increasing heterogeneity
-
T. Tuomi, N. Santoro, S. Caprio, M. Cai, J. Weng, and L. Groop The many faces of diabetes: a disease with increasing heterogeneity Lancet 383 2014 1084 1094
-
(2014)
Lancet
, vol.383
, pp. 1084-1094
-
-
Tuomi, T.1
Santoro, N.2
Caprio, S.3
Cai, M.4
Weng, J.5
Groop, L.6
-
137
-
-
84896313869
-
Diagnosis and classification of autoimmune diabetes mellitus
-
S. Canivell, and R. Gomis Diagnosis and classification of autoimmune diabetes mellitus Autoimmun Rev 13 2014 403 407
-
(2014)
Autoimmun Rev
, vol.13
, pp. 403-407
-
-
Canivell, S.1
Gomis, R.2
-
138
-
-
67049159857
-
Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: A multicentre prospective registration study
-
C.C. Patterson, G.G. Dahlquist, E. Gyürüs, A. Green, and G. Soltész Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study Lancet 373 2009 2027 2033
-
(2009)
Lancet
, vol.373
, pp. 2027-2033
-
-
Patterson, C.C.1
Dahlquist, G.G.2
Gyürüs, E.3
Green, A.4
Soltész, G.5
-
139
-
-
79959409408
-
Efficacy of metreleptin in obese patients with type 2 diabetes: Cellular and molecular pathways underlying leptin tolerance
-
H.S. Moon, G. Matarese, A.M. Brennan, J.P. Chamberland, X. Liu, and C.G. Fiorenza Efficacy of metreleptin in obese patients with type 2 diabetes: cellular and molecular pathways underlying leptin tolerance Diabetes 60 2011 1647 1656
-
(2011)
Diabetes
, vol.60
, pp. 1647-1656
-
-
Moon, H.S.1
Matarese, G.2
Brennan, A.M.3
Chamberland, J.P.4
Liu, X.5
Fiorenza, C.G.6
-
140
-
-
33644781754
-
Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis
-
C.H. Lee, Y.G. Chen, J. Chen, P.C. Reifsnyder, D.V. Serreze, and M. Clare-Salzler Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis Diabetes 55 2006 171 178
-
(2006)
Diabetes
, vol.55
, pp. 171-178
-
-
Lee, C.H.1
Chen, Y.G.2
Chen, J.3
Reifsnyder, P.C.4
Serreze, D.V.5
Clare-Salzler, M.6
-
141
-
-
24144432204
-
Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis
-
C.H. Lee, P.C. Reifsnyder, J.K. Naggert, C. Wasserfall, M.A. Atkinson, and J. Chen Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis Diabetes 54 2005 2525 2532
-
(2005)
Diabetes
, vol.54
, pp. 2525-2532
-
-
Lee, C.H.1
Reifsnyder, P.C.2
Naggert, J.K.3
Wasserfall, C.4
Atkinson, M.A.5
Chen, J.6
-
142
-
-
74549140993
-
Prevalence and trends in obesity among US adults, 1999-2008
-
K.M. Flegal, M.D. Carroll, C.L. Ogden, and L.R. Curtin Prevalence and trends in obesity among US adults, 1999-2008 JAMA 303 2010 235 241
-
(2010)
JAMA
, vol.303
, pp. 235-241
-
-
Flegal, K.M.1
Carroll, M.D.2
Ogden, C.L.3
Curtin, L.R.4
-
143
-
-
0034932098
-
The accelerator hypothesis: Weight gain as the missing link between type i and type II diabetes
-
T.J. Wilkin The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes Diabetologia 44 2001 914 922
-
(2001)
Diabetologia
, vol.44
, pp. 914-922
-
-
Wilkin, T.J.1
-
144
-
-
0027976643
-
A high weight gain in early life is associated with an increased risk of type 1 (insulin-dependent) diabetes
-
C. Johansson, U. Samuelsson, and J. Ludvigsson A high weight gain in early life is associated with an increased risk of type 1 (insulin-dependent) diabetes Diabetologia 37 1994 91 94
-
(1994)
Diabetologia
, vol.37
, pp. 91-94
-
-
Johansson, C.1
Samuelsson, U.2
Ludvigsson, J.3
-
145
-
-
0028060360
-
High juvenile body weight and low insulin levels as markers preceding early diabetes in the BB rat
-
C.R. Pedersen, T. Bock, S.V. Hansen, M.W. Hansen, and K. Buschard High juvenile body weight and low insulin levels as markers preceding early diabetes in the BB rat Autoimmunity 17 1994 261 269
-
(1994)
Autoimmunity
, vol.17
, pp. 261-269
-
-
Pedersen, C.R.1
Bock, T.2
Hansen, S.V.3
Hansen, M.W.4
Buschard, K.5
-
146
-
-
34147130286
-
In utero undernutrition reduces diabetes incidence in non-obese diabetic mice
-
A. Oge, E. Isganaitis, J. Jimenez-Chillaron, C. Reamer, R. Faucette, and K. Barry In utero undernutrition reduces diabetes incidence in non-obese diabetic mice Diabetologia 50 2007 1099 1108
-
(2007)
Diabetologia
, vol.50
, pp. 1099-1108
-
-
Oge, A.1
Isganaitis, E.2
Jimenez-Chillaron, J.3
Reamer, C.4
Faucette, R.5
Barry, K.6
-
147
-
-
0033660085
-
Obesity, increased linear growth, and risk of type 1 diabetes in children
-
E. Hypponen, S.M. Virtanen, M.G. Kenward, M. Knip, and H.K. Akerblom Obesity, increased linear growth, and risk of type 1 diabetes in children Diabetes Care 23 2000 1755 1760
-
(2000)
Diabetes Care
, vol.23
, pp. 1755-1760
-
-
Hypponen, E.1
Virtanen, S.M.2
Kenward, M.G.3
Knip, M.4
Akerblom, H.K.5
-
148
-
-
0034686954
-
Association between infant growth before onset of juvenile type-1 diabetes and autoantibodies to IA-2
-
G.J. Bruining Association between infant growth before onset of juvenile type-1 diabetes and autoantibodies to IA-2 Lancet 356 2000 655 656
-
(2000)
Lancet
, vol.356
, pp. 655-656
-
-
Bruining, G.J.1
-
149
-
-
0141446269
-
Testing the accelerator hypothesis: The relationship between body mass and age at diagnosis of type 1 diabetes
-
M. Kibirige, B. Metcalf, R. Renuka, and T.J. Wilkin Testing the accelerator hypothesis: the relationship between body mass and age at diagnosis of type 1 diabetes Diabetes Care 26 2003 2865 2870
-
(2003)
Diabetes Care
, vol.26
, pp. 2865-2870
-
-
Kibirige, M.1
Metcalf, B.2
Renuka, R.3
Wilkin, T.J.4
-
150
-
-
13444304163
-
Increasing body weight predicts the earlier onset of insulin-dependant diabetes in childhood: Testing the "accelerator hypothesis"
-
P. Betts, J. Mulligan, P. Ward, B. Smith, and T.J. Wilkin Increasing body weight predicts the earlier onset of insulin-dependant diabetes in childhood: testing the "accelerator hypothesis" Diabet Med 22 2005 144 151
-
(2005)
Diabet Med
, vol.22
, pp. 144-151
-
-
Betts, P.1
Mulligan, J.2
Ward, P.3
Smith, B.4
Wilkin, T.J.5
-
151
-
-
28444458516
-
The "accelerator hypothesis": Relationship between weight, height, body mass index and age at diagnosis in a large cohort of 9248 German and Austrian children with type 1 diabetes mellitus
-
I. Knerr, J. Wolf, T. Reinehr, R. Stachow, M. Grabert, and E. Schober The "accelerator hypothesis": relationship between weight, height, body mass index and age at diagnosis in a large cohort of 9248 German and Austrian children with type 1 diabetes mellitus Diabetologia 48 2005 2501 2504
-
(2005)
Diabetologia
, vol.48
, pp. 2501-2504
-
-
Knerr, I.1
Wolf, J.2
Reinehr, T.3
Stachow, R.4
Grabert, M.5
Schober, E.6
-
152
-
-
30044444444
-
Higher body weight is associated with earlier onset of type 1 diabetes in children: Confirming the "accelerator Hypothesis"
-
O. Kordonouri, and R. Hartmann Higher body weight is associated with earlier onset of type 1 diabetes in children: confirming the "Accelerator Hypothesis" Diabet Med 22 2005 1783 1784
-
(2005)
Diabet Med
, vol.22
, pp. 1783-1784
-
-
Kordonouri, O.1
Hartmann, R.2
-
153
-
-
0038222568
-
Temporal changes in the frequencies of HLA genotypes in patients with type i diabetes - Indication of an increased environmental pressure?
-
R. Hermann, M. Knip, and R. Veijola Temporal changes in the frequencies of HLA genotypes in patients with type I diabetes - indication of an increased environmental pressure? Diabetologia 46 2003 420 425
-
(2003)
Diabetologia
, vol.46
, pp. 420-425
-
-
Hermann, R.1
Knip, M.2
Veijola, R.3
-
154
-
-
34548431028
-
Role of insulin resistance in predicting progression to type 1 diabetes
-
P. Xu, J.P. Krischer, D. Cuthbertson, C. Greenbaum, and J.P. Palmer Role of insulin resistance in predicting progression to type 1 diabetes Diabetes Care 30 2007 2314 2320
-
(2007)
Diabetes Care
, vol.30
, pp. 2314-2320
-
-
Xu, P.1
Krischer, J.P.2
Cuthbertson, D.3
Greenbaum, C.4
Palmer, J.P.5
-
156
-
-
11144298970
-
Insulin resistance is a risk factor for progression to type 1 diabetes
-
S. Fourlanos, P. Narendran, G.B. Byrnes, P.G. Colman, and L.C. Harrison Insulin resistance is a risk factor for progression to type 1 diabetes Diabetologia 47 2004 1661 1667
-
(2004)
Diabetologia
, vol.47
, pp. 1661-1667
-
-
Fourlanos, S.1
Narendran, P.2
Byrnes, G.B.3
Colman, P.G.4
Harrison, L.C.5
-
157
-
-
19944361859
-
No evidence for genetically determined alteration in insulin secretion or sensitivity predisposing to type 1 diabetes: A study of identical twins
-
M.I. Hawa, R. Bonfanti, C. Valeri, M. Delli Castelli, H. Beyan, and R.D. Leslie No evidence for genetically determined alteration in insulin secretion or sensitivity predisposing to type 1 diabetes: a study of identical twins Diabetes Care 28 2005 1415 1418
-
(2005)
Diabetes Care
, vol.28
, pp. 1415-1418
-
-
Hawa, M.I.1
Bonfanti, R.2
Valeri, C.3
Delli Castelli, M.4
Beyan, H.5
Leslie, R.D.6
-
158
-
-
84903935556
-
Absence of leptin triggers type 1 diabetes
-
B. Mittendorfer, and S. Klein Absence of leptin triggers type 1 diabetes Nat Med 20 2014 705 706
-
(2014)
Nat Med
, vol.20
, pp. 705-706
-
-
Mittendorfer, B.1
Klein, S.2
-
159
-
-
84904000735
-
Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis
-
R.J. Perry, X.M. Zhang, D. Zhang, N. Kumashiro, J.P. Camporez, and G.W. Cline Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis Nat Med 20 2014 759 763
-
(2014)
Nat Med
, vol.20
, pp. 759-763
-
-
Perry, R.J.1
Zhang, X.M.2
Zhang, D.3
Kumashiro, N.4
Camporez, J.P.5
Cline, G.W.6
-
160
-
-
52949140814
-
Making insulin-deficient type 1 diabetic rodents thrive without insulin
-
X. Yu, B.H. Park, M.Y. Wang, Z.V. Wang, and R.H. Unger Making insulin-deficient type 1 diabetic rodents thrive without insulin Proc Natl Acad Sci U S A 105 2008 14070 14075
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14070-14075
-
-
Yu, X.1
Park, B.H.2
Wang, M.Y.3
Wang, Z.V.4
Unger, R.H.5
-
161
-
-
77950373635
-
Leptin therapy in insulin-deficient type i diabetes
-
M.Y. Wang, L. Chen, G.O. Clark, Y. Lee, R.D. Stevens, and O.R. Ilkayeva Leptin therapy in insulin-deficient type I diabetes Proc Natl Acad Sci U S A 107 2010 4813 4819
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4813-4819
-
-
Wang, M.Y.1
Chen, L.2
Clark, G.O.3
Lee, Y.4
Stevens, R.D.5
Ilkayeva, O.R.6
-
162
-
-
79551569614
-
Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats
-
A.J. Kruger, C. Yang, K.L. Lipson, S.C. Pino, J.H. Leif, and C.M. Hogan Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats Autoimmunity 44 2011 137 148
-
(2011)
Autoimmunity
, vol.44
, pp. 137-148
-
-
Kruger, A.J.1
Yang, C.2
Lipson, K.L.3
Pino, S.C.4
Leif, J.H.5
Hogan, C.M.6
-
163
-
-
80052900602
-
Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice
-
M. Naito, J. Fujikura, K. Ebihara, F. Miyanaga, H. Yokoi, and T. Kusakabe Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice Diabetes 60 2011 2265 2273
-
(2011)
Diabetes
, vol.60
, pp. 2265-2273
-
-
Naito, M.1
Fujikura, J.2
Ebihara, K.3
Miyanaga, F.4
Yokoi, H.5
Kusakabe, T.6
-
165
-
-
79953000642
-
Psoriatic arthritis: Update on pathophysiology, assessment and management
-
P.J. Mease Psoriatic arthritis: update on pathophysiology, assessment and management Ann Rheum Dis 70 Suppl. 1 2011 i77 i84
-
(2011)
Ann Rheum Dis
, vol.70
, pp. i77-i84
-
-
Mease, P.J.1
-
166
-
-
77950150415
-
Psoriasis and body mass index
-
J. Hercogová, F. Ricceri, L. Tripo, T. Lotti, and F. Prignano Psoriasis and body mass index Dermatol Ther 23 2010 152 154
-
(2010)
Dermatol Ther
, vol.23
, pp. 152-154
-
-
Hercogová, J.1
Ricceri, F.2
Tripo, L.3
Lotti, T.4
Prignano, F.5
-
167
-
-
22144490239
-
Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: Results from an Italian case control study
-
L. Naldi, L. Chatenoud, D. Linder, A. Belloni Fortina, and A. Peserico Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian case control study J Invest Dermatol 125 2005 61 67
-
(2005)
J Invest Dermatol
, vol.125
, pp. 61-67
-
-
Naldi, L.1
Chatenoud, L.2
Linder, D.3
Belloni Fortina, A.4
Peserico, A.5
-
169
-
-
84879241693
-
Leptin levels in patients with psoriasis: A meta-analysis
-
K.J. Zhu, C. Zhang, M. Li, C.Y. Zhu, G. Shi, and Y.M. Fan Leptin levels in patients with psoriasis: a meta-analysis Clin Exp Dermatol 38 2013 478 483
-
(2013)
Clin Exp Dermatol
, vol.38
, pp. 478-483
-
-
Zhu, K.J.1
Zhang, C.2
Li, M.3
Zhu, C.Y.4
Shi, G.5
Fan, Y.M.6
-
170
-
-
33845426317
-
What are subcutaneous adipocytes really good for?
-
J. Klein, P.A. Permana, and M. Owecki What are subcutaneous adipocytes really good for? Exp Dermatol 16 2007 45 70
-
(2007)
Exp Dermatol
, vol.16
, pp. 45-70
-
-
Klein, J.1
Permana, P.A.2
Owecki, M.3
-
171
-
-
0033862589
-
Leptin enhances wound reepithelialization and constitutes a direct function of leptin in skin repair
-
S. Frank, B. Stallmeyer, H. Kämpfer, N. Kolb, and J. Pfeilschifter Leptin enhances wound reepithelialization and constitutes a direct function of leptin in skin repair J Clin Invest 106 2000 501 509
-
(2000)
J Clin Invest
, vol.106
, pp. 501-509
-
-
Frank, S.1
Stallmeyer, B.2
Kämpfer, H.3
Kolb, N.4
Pfeilschifter, J.5
-
172
-
-
0034852245
-
Expression of leptin (Ob) and leptin receptor (Ob-R) in human fibroblasts: Regulation of leptin secretion by insulin
-
A. Glasow, W. Kiess, U. Anderegg, A. Berthold, A. Bottner, and J. Kratzsch Expression of leptin (Ob) and leptin receptor (Ob-R) in human fibroblasts: regulation of leptin secretion by insulin J Clin Endocrinol Metab 86 2001 4472 4479
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4472-4479
-
-
Glasow, A.1
Kiess, W.2
Anderegg, U.3
Berthold, A.4
Bottner, A.5
Kratzsch, J.6
-
173
-
-
0034946908
-
A novel keratinocyte mitogen: Regulation of leptin and its functional receptor in skin repair
-
B. Stallmeyer, H. Kàmpfer, M. Podda, R. Kaufmann, J. Pfeilschifter, and S. Frank A novel keratinocyte mitogen: regulation of leptin and its functional receptor in skin repair J Invest Dermatol 117 1 2001 98 105
-
(2001)
J Invest Dermatol
, vol.117
, Issue.1
, pp. 98-105
-
-
Stallmeyer, B.1
Kàmpfer, H.2
Podda, M.3
Kaufmann, R.4
Pfeilschifter, J.5
Frank, S.6
-
174
-
-
84924020511
-
Relationships between adipose tissue and psoriasis, with or without arthritis
-
E. Toussirot, F. Aubin, and G. Dumoulin Relationships between adipose tissue and psoriasis, with or without arthritis Front Immunol 5 2014 368
-
(2014)
Front Immunol
, vol.5
, pp. 368
-
-
Toussirot, E.1
Aubin, F.2
Dumoulin, G.3
-
175
-
-
42049121958
-
Psoriasis is associated with increased levels of serum leptin
-
Y. Wang, J. Chen, Y. Zhao, L. Geng, F. Song, and H.D. Chen Psoriasis is associated with increased levels of serum leptin Br J Dermatol 158 5 2008 1134 1135
-
(2008)
Br J Dermatol
, vol.158
, Issue.5
, pp. 1134-1135
-
-
Wang, Y.1
Chen, J.2
Zhao, Y.3
Geng, L.4
Song, F.5
Chen, H.D.6
-
176
-
-
47549113861
-
Obesity in psoriasis: Leptin and resistin as mediators of cutaneous inflammation
-
A. Johnston, S. Arnadottir, J.E. Gudjonsson, A. Aphale, A.A. Sigmarsdottir, and S.I. Gunnarsson Obesity in psoriasis: leptin and resistin as mediators of cutaneous inflammation Br J Dermatol 159 2008 342 350
-
(2008)
Br J Dermatol
, vol.159
, pp. 342-350
-
-
Johnston, A.1
Arnadottir, S.2
Gudjonsson, J.E.3
Aphale, A.4
Sigmarsdottir, A.A.5
Gunnarsson, S.I.6
-
177
-
-
51849121583
-
Serum leptin levels, skin leptin and leptin receptor expression in psoriasis
-
A.A. Cerman, S. Bozkurt, A. Sav, A. Tulunay, M.O. Elbaşi, and T. Ergun Serum leptin levels, skin leptin and leptin receptor expression in psoriasis Br J Dermatol 159 2008 820 826
-
(2008)
Br J Dermatol
, vol.159
, pp. 820-826
-
-
Cerman, A.A.1
Bozkurt, S.2
Sav, A.3
Tulunay, A.4
Elbaşi, M.O.5
Ergun, T.6
-
178
-
-
54249085479
-
Plasma adiponectin and leptin levels in Japanese patients with psoriasis
-
H. Takahashi, H. Tsuji, and I. Takahashi Plasma adiponectin and leptin levels in Japanese patients with psoriasis Br J Dermatol 159 2008 1207 1208
-
(2008)
Br J Dermatol
, vol.159
, pp. 1207-1208
-
-
Takahashi, H.1
Tsuji, H.2
Takahashi, I.3
-
179
-
-
58049198305
-
Psoriasis independently associated with hyperleptinemia contributing to metabolic syndrome
-
Y.J. Chen, C.Y. Wu, J.L. Shen, S.Y. Chu, C.K. Chen, and Y.T. Chang Psoriasis independently associated with hyperleptinemia contributing to metabolic syndrome Arch Dermatol 144 2008 1571 1575
-
(2008)
Arch Dermatol
, vol.144
, pp. 1571-1575
-
-
Chen, Y.J.1
Wu, C.Y.2
Shen, J.L.3
Chu, S.Y.4
Chen, C.K.5
Chang, Y.T.6
-
180
-
-
84867403047
-
The incidence and prevalence of thyroid autoimmunity
-
D.S.A. McLeod, and D.S. Cooper The incidence and prevalence of thyroid autoimmunity Endocrine 42 2012 252 265
-
(2012)
Endocrine
, vol.42
, pp. 252-265
-
-
McLeod, D.S.A.1
Cooper, D.S.2
-
181
-
-
66749185880
-
Clinical review: Prevalence and incidence of endocrine and metabolic disorders in the United States: A comprehensive review
-
S.H. Golden, K.A. Robinson, I. Saldanha, B. Anton, and P.W. Ladenson Clinical review: prevalence and incidence of endocrine and metabolic disorders in the United States: a comprehensive review J Clin Endocrinol Metab 94 2009 1853 1878
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1853-1878
-
-
Golden, S.H.1
Robinson, K.A.2
Saldanha, I.3
Anton, B.4
Ladenson, P.W.5
-
182
-
-
80052703117
-
The epidemiology of thyroid disease
-
M.P.J. Vanderpump The epidemiology of thyroid disease Br Med Bull 99 2011 39 51
-
(2011)
Br Med Bull
, vol.99
, pp. 39-51
-
-
Vanderpump, M.P.J.1
-
183
-
-
84896319312
-
Hashimoto thyroiditis: Clinical and diagnostic criteria
-
P. Caturegli, A. De Remigis, and N.R. Rose Hashimoto thyroiditis: clinical and diagnostic criteria Autoimmun Rev 13 2014 391 397
-
(2014)
Autoimmun Rev
, vol.13
, pp. 391-397
-
-
Caturegli, P.1
De Remigis, A.2
Rose, N.R.3
-
184
-
-
71649099616
-
Environmental triggers of autoimmune thyroiditis
-
C.L. Burek, and M.V. Talor Environmental triggers of autoimmune thyroiditis J Autoimmun 33 2009 183 189
-
(2009)
J Autoimmun
, vol.33
, pp. 183-189
-
-
Burek, C.L.1
Talor, M.V.2
-
185
-
-
84876249699
-
An overview of the pathogenesis of thyroid autoimmunity
-
G. Cogni, and L. Chiovato An overview of the pathogenesis of thyroid autoimmunity Hormones (Athens) 12 2013 19 29
-
(2013)
Hormones (Athens)
, vol.12
, pp. 19-29
-
-
Cogni, G.1
Chiovato, L.2
-
186
-
-
41549160725
-
Relations of thyroid function to body weight: Cross-sectional and longitudinal observations in a community-based sample
-
C.S. Fox, M.J. Pencina, R.B. D'Agostino, J.M. Murabito, E.W. Seely, and E.N. Pearce Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample Arch Intern Med 168 2008 587 592
-
(2008)
Arch Intern Med
, vol.168
, pp. 587-592
-
-
Fox, C.S.1
Pencina, M.J.2
D'Agostino, R.B.3
Murabito, J.M.4
Seely, E.W.5
Pearce, E.N.6
-
188
-
-
84911002430
-
Sustained high levels of serum leptin rather than IL-6 observed in patients with postpartum thyroiditis during their first postpartum year
-
H. Guo, X. Liu, C. Li, Y. Li, M. Sang, and Z. Shan Sustained high levels of serum leptin rather than IL-6 observed in patients with postpartum thyroiditis during their first postpartum year Endocrine 2014 10.1007/s12020-014-0176-3
-
(2014)
Endocrine
-
-
Guo, H.1
Liu, X.2
Li, C.3
Li, Y.4
Sang, M.5
Shan, Z.6
-
189
-
-
0033829574
-
Thyroid hormones influence serum leptin levels in patients with Graves' disease during suppression of beta-adrenergic receptors
-
N. Sera, N. Yokoyama, Y. Abe, A. Ide, M. Imaizumi, and T. Usa Thyroid hormones influence serum leptin levels in patients with Graves' disease during suppression of beta-adrenergic receptors Thyroid 10 2000 641 646
-
(2000)
Thyroid
, vol.10
, pp. 641-646
-
-
Sera, N.1
Yokoyama, N.2
Abe, Y.3
Ide, A.4
Imaizumi, M.5
Usa, T.6
-
190
-
-
0035044152
-
Induction of leptin expression in orbital preadipocyte fibroblasts
-
D.Z. Erickson, D.A. Harteneck, B.J. Erickson, C.M. Dutton, and R.S. Bahn Induction of leptin expression in orbital preadipocyte fibroblasts Thyroid 11 2001 221 226
-
(2001)
Thyroid
, vol.11
, pp. 221-226
-
-
Erickson, D.Z.1
Harteneck, D.A.2
Erickson, B.J.3
Dutton, C.M.4
Bahn, R.S.5
-
191
-
-
67650381823
-
Serum leptin in overt and subclinical hypothyroidism: Effect of levothyroxine treatment and relationship to menopausal status and body composition
-
P.F. Teixeira, M.D. Cabral, N.A. Silva, D.V. Soares, V.B. Braulio, and A.P. Couto Serum leptin in overt and subclinical hypothyroidism: effect of levothyroxine treatment and relationship to menopausal status and body composition Thyroid 19 2009 443 450
-
(2009)
Thyroid
, vol.19
, pp. 443-450
-
-
Teixeira, P.F.1
Cabral, M.D.2
Silva, N.A.3
Soares, D.V.4
Braulio, V.B.5
Couto, A.P.6
-
192
-
-
77955347038
-
Investigations of thyroid hormones and antibodies in obesity: Leptin levels are associated with thyroid
-
P. Marzullo, A. Minocci, M.A. Tagliaferri, G. Guzzaloni, A. Di Blasio, and C. De Medici Investigations of thyroid hormones and antibodies in obesity: leptin levels are associated with thyroid J Clin Endocrinol Metab 95 2014 3965 3972
-
(2014)
J Clin Endocrinol Metab
, vol.95
, pp. 3965-3972
-
-
Marzullo, P.1
Minocci, A.2
Tagliaferri, M.A.3
Guzzaloni, G.4
Di Blasio, A.5
De Medici, C.6
-
193
-
-
84876248594
-
Childhood weight gain and thyroid autoimmunity at age 60-64 years: The 1946 British Birth Cohort Study
-
K.K. Ong, D. Kuh, M. Pierce, and J.A. Franklyn Childhood weight gain and thyroid autoimmunity at age 60-64 years: the 1946 British Birth Cohort Study J Clin Endocrinol Metab 98 2014 1435 1442
-
(2014)
J Clin Endocrinol Metab
, vol.98
, pp. 1435-1442
-
-
Ong, K.K.1
Kuh, D.2
Pierce, M.3
Franklyn, J.A.4
-
194
-
-
84870475160
-
T cell-derived leptin contributes to increased frequency of T helper type 17 cells in female patients with Hashimoto's thyroiditis
-
S. Wang, S.E. Baidoo, Y. Liu, C. Zhu, J. Tian, and J. Ma T cell-derived leptin contributes to increased frequency of T helper type 17 cells in female patients with Hashimoto's thyroiditis Clin Exp Immunol 171 2012 63 68
-
(2012)
Clin Exp Immunol
, vol.171
, pp. 63-68
-
-
Wang, S.1
Baidoo, S.E.2
Liu, Y.3
Zhu, C.4
Tian, J.5
Ma, J.6
-
195
-
-
76149084482
-
Increased circulating pro-inflammatory cytokines and Th17 lymphocytes in Hashimoto's thyroiditis
-
N. Figueroa-Vega, M. Alfonso-Pérez, I. Benedicto, F. Sánchez-Madrid, R. González- Amaro, and M. Marazuela Increased circulating pro-inflammatory cytokines and Th17 lymphocytes in Hashimoto's thyroiditis J Clin Endocrinol Metab 95 2010 953 962
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 953-962
-
-
Figueroa-Vega, N.1
Alfonso-Pérez, M.2
Benedicto, I.3
Sánchez-Madrid, F.4
González- Amaro, R.5
Marazuela, M.6
-
196
-
-
77955298749
-
Differentiation imbalance of Th1/Th17 in peripheral blood mononuclear cells might contribute to pathogenesis of Hashimoto's thyroiditis
-
Y. Shi, H. Wang, Z. Su, J. Chen, Y. Xue, and S. Wang Differentiation imbalance of Th1/Th17 in peripheral blood mononuclear cells might contribute to pathogenesis of Hashimoto's thyroiditis Scand J Immunol 72 2010 250 255
-
(2010)
Scand J Immunol
, vol.72
, pp. 250-255
-
-
Shi, Y.1
Wang, H.2
Su, Z.3
Chen, J.4
Xue, Y.5
Wang, S.6
-
197
-
-
34047155003
-
Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
-
L. Fontana, J.C. Eagon, M.E. Trujillo, P.E. Scherer, and S. Klein Visceral fat adipokine secretion is associated with systemic inflammation in obese humans Diabetes 56 2007 1010 1013
-
(2007)
Diabetes
, vol.56
, pp. 1010-1013
-
-
Fontana, L.1
Eagon, J.C.2
Trujillo, M.E.3
Scherer, P.E.4
Klein, S.5
-
198
-
-
79957480178
-
Obesity and susceptibility to autoimmune diseases
-
C. Procaccini, F. Carbone, M. Galgani, C. La Rocca, V. De Rosa, and S. Cassano Obesity and susceptibility to autoimmune diseases Expert Rev Clin Immunol 7 2011 287 294
-
(2011)
Expert Rev Clin Immunol
, vol.7
, pp. 287-294
-
-
Procaccini, C.1
Carbone, F.2
Galgani, M.3
La Rocca, C.4
De Rosa, V.5
Cassano, S.6
-
199
-
-
33748992313
-
Adipocytokines: Mediators linking adipose tissue, inflammation and immunity
-
H. Tilg, and A.R. Moschen Adipocytokines: mediators linking adipose tissue, inflammation and immunity Nat Rev Immunol 6 2006 772 783
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 772-783
-
-
Tilg, H.1
Moschen, A.R.2
|