Leptin serum levels are not correlated with disease activity in patients with rheumatoid arthritis

Metabolism: Clinical and Experimental

Volumn 48, Issue 6, 1999, Pages 745-748

  Anders, Hans Joachim ^a   Rihl, Markus ^b   Heufelder, Armin ^b   Loch, Oliver ^b   Schattenkirchner, Manfred ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; INTERLEUKIN 2; LEPTIN;

ADULT; AGED; ARTICLE; BODY FAT; BODY MASS; CACHEXIA; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE CLASSIFICATION; DISEASE SEVERITY; ERYTHROCYTE SEDIMENTATION RATE; FOOD INTAKE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; RADIOIMMUNOASSAY; RHEUMATOID ARTHRITIS; SCORING SYSTEM;

EID: 0033002314     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(99)90174-9     Document Type: Article

References (40)

1. Zhang Y, Proenca R, Maffei M, et al: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432, 1994
2. Masuzaki H, Ogawa Y, Isse N, et al: Human obese gene expression: Adipocyte-specific expression and regional differences in the adipose tissue. Diabetes 44:855-858, 1995
3. Jaquet D, Leger J, Levy-Marchal C, et al: Ontogeny of leptin in human fetuses and newborns: Effect of intrauterine growth retardation on serum leptin concentrations. J Clin Endocrinol Metab 83:1243-1246, 1998
4. Halaas JL, Gajiwala KS, Maffei M, et al: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546, 1995
5. Pelleymounter MA, Cullen MJ, Baker MB, et al: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543, 1995
6. Hickey MS, Israel RG, Gardiner SN, et al: Gender differences in serum leptin levels in humans. Biochem Mol Med 59:1-6, 1996
7. Hickey MS, Considine RV, Israel RG, et al: Leptin is correlated to body fat content in male distance runners. Am J Physiol 271:E938-E940, 1996
8. Considine RV, Sinha MK, Heiman ML, et al: Serum immunoreactive leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295, 1996
9. Haffner SM, Mykkanen L, Stern MP: Leptin concentrations in women in the San Antonio Heart Study: Effect of menopausal status and postmenopausal hormone replacement therapy. Am J Epidemiol 146:581-585, 1997
10. Grinspoon S, Gulick T, Askari H, et al: Serum leptin levels in women with anorexia nervosa. J Clin Endocrinol Metab 81:3861-3863, 1996
11. Maffei M, Halaas J, Ravussin E, et al: Leptin levels in human and rodent: Measurements of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161, 1995
12. Ostlund RE, Yang JW, Klein S, et al: Relation between plasma leptin concentration and body fat, gender, diet, age, and metabolic covariates. J Clin Endocrinol Metab 81:3909-3913, 1996
13. Rosenbaum M, Nicholson M, Hirsch J, et al: Effects of weight change on plasma leptin concentrations and energy expenditure. J Clin Endocrinol Metab 82:3647-3654, 1997
14. Vidal H, Auboeuf D, DeVos P, et al: The expression of ob gene is not acutely regulated by insulin and fasting in human abdominal subcutaneous adipose tissue. J Clin Invest 98:251-255, 1996
15. Sarraf P, Frederich RC, Turner EM, et al: Multiple cytokines and acute inflammation raise mouse leptin levels: Potential role in inflammatory anorexia. J Exp Med 185:171-175, 1997
16. Finck BN, Kelley KW, Dantzer R, et al: In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide. Endocrinology 139:2278-2283, 1998
17. Grunfeld C, Zhao C, Fuller J, et al: Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. A role for leptin in the anorexia of infection. J Clin Invest 97:2152-2157, 1996
18. Socher SH, Friedman A, Martinez D: Recombinant human tumor necrosis factor induces acute reductions in food intake and body weight in mice. J Exp Med 167:1957-1962, 1988
19. Janik JE, Curti BD, Considine RV, et al: Interleukin 1 alpha increases serum leptin concentrations in humans. J Clin Endocrinol Metab 82:3084-3086, 1997
20. Zumbach MS, Boehme MW, Wahl P, et al: Tumor necrosis factor increases serum leptin levels in humans. J Clin Endocrinol Metab 82:4080-4082, 1997
21. Bornstein SR, Licino J, Tauchnitz R, et al: Plasma leptin levels are increased in survivors of acute sepsis: Associated loss of diurnal rhythm in cortisol and leptin secretion. J Clin Endocrinol Metab 83:280-283, 1998
22. Stratton RJ, Dewit O, Crowe E, et al: Plasma leptin, energy intake and hunger following total hip replacement surgery. Clin Sei 93:113-117, 1997
23. Grunfeld C, Pang M, Shigenaga JK, et al: Serum leptin levels in the acquired immunodeficiency syndrome. J Clin Endocrinol Metab 81:4342-4346, 1996
24. Hoppin AG, Kaplan LM, Zurakowski D, et al: Serum leptin in children and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 26:500-505, 1998
25. Simons JP, Schols AM, Campfield LA, et al: Plasma concentration of total leptin and human lung cancer-associated cachexia. Clin Sci Colch 93:273-277, 1997
26. Yaresheski KE, Zachwieja JJ, Horgan MM, et al: Serum leptin concentrations in human immunodeficiency virus-infected men with low adiposity. Metabolism 46:303-305, 1997
27. Altomonte L, Zoli A, Mirone L, et al: Serum levels of interleukin-1β, tumor necrosis factor-α and interleukin-2 in rheumatoid arthritis. Correlation with disease activity. Clin Rheumatol 11:202-205, 1992
28. Badolato R, Oppenheim JJ: Role of cytokines, acute phase proteins, and chemokines in the progression of rheumatoid arthritis. Semin Arthritis Rheum 26:526-538, 1996
29. Vreugdenhil G, Lowenberg B, Van Eijk HG, et al: Tumor necrosis factor alpha is associated with disease activity and the degree of anemia in patients with rheumatoid arthritis. Eur J Clin Invest 22:488-493, 1992
30. Roubenoff R, Roubenoff RA, Ward LM, et al: Rheumatoid cachexia: Depletion of lean body mass in rheumatoid arthritis. Possible association with tumor necrosis factor. J Rheumatol 19:1505-1510, 1992
31. van der Heijde DM, van't Hof MA, van Riel PL, et al: Development of Disease Activity Score based on judgement in clinical practice by rheumatologists. J Rheumatol 20:579-581, 1993
32. Segal KR, Van Loan M, Fitzgerald PI, et al: Lean body mass estimation by bioelectrical impedance analysis: A four sites cross-validation study. Am J Clin Nutr 47:7-14, 1988
33. Heitmann BL, Kondrup J, Engelhart M, et al: Changes in fat-free body mass in overweight patients with rheumatoid arthritis on a weight reducing regimen. A comparison of eight different body composition methods. Int J Obes Relat Metab Disord 18:812-819, 1994
34. Moshyedi AK, Josephs MD, Abdalla EK, et al: Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha. Infect Immun 66:1800-1802, 1998
35. Lorenz HM, Antoni C, Valerius T, et al: In vivo blockade of TNF-alpha by intravenous infusion of a chimeric monoclonal TNF-alpha antibody in patients with rheumatoid arthritis. J Immunol 156:1646-1653, 1996
36. Moreland LW, Baumgartner SW, Schiff MH, et al: Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 337:141-147, 1997
37. Granowitz EV: Transforming growth factor-beta enhances and proinflammatory cytokines inhibit ob gene expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun 240:382-385, 1997
38. Yamaguchi M, Murakami T, Tomimatsu T, et al: Autocrine inhibition of leptin production by tumor necrosis factor-alpha (TNF-alpha) through TNF-alpha type-1 receptor in vitro. Biochem Biophys Res Commun 244:30-34, 1998
39. Cizza G, Lotsikas AJ, Licinio J, et al: Plasma leptin levels do not change in patients with Cushing's disease shortly after correction of hypercortisolism. J Clin Endocrinol Metab 82:2747-2750, 1997
40. Danis VA, Franic GM, Rathjen DA, et al: Circulating cytokine levels in patients with rheumatoid arthritis: Results of a double blind trial with sulphasalazine. Ann Rheum Dis 51:946-950, 1992