-
3
-
-
0032741972
-
Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice
-
(1999)
J Clin Invest
, vol.104
, pp. 1051-1059
-
-
Howard, J.K.1
Lord, G.M.2
Matarese, G.3
Vendetti, S.4
Ghatei, M.A.5
Ritter, M.A.6
Lechler, R.I.7
Bloom, S.R.8
-
4
-
-
0033304576
-
Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 3686-3695
-
-
Ozata, M.1
Ozdemir, I.C.2
Licinio, J.3
-
7
-
-
0029776030
-
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 8374-8378
-
-
Baumann, H.1
Morella, K.K.2
White, D.W.3
Dembski, M.4
Bailon, P.S.5
Kim, H.6
Lai, C.F.7
Tartaglia, L.A.8
-
8
-
-
0030977992
-
Crystal structure of the obese protein leptin-E100
-
(1997)
Nature
, vol.387
, pp. 206-209
-
-
Zhang, F.1
Basinski, M.B.2
Beals, J.M.3
Briggs, S.L.4
Churgay, L.M.5
Clawson, D.K.6
DiMarchi, R.D.7
Furman, T.C.8
Hale, J.E.9
Hsiung, H.M.10
Schoner, B.E.11
Smith, D.P.12
Zhang, X.Y.13
Wery, J.P.14
Schevitz, R.W.15
-
10
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.H.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
De Woody, K.7
Schaible, T.F.8
Rutgeerts, P.J.9
-
12
-
-
0035910753
-
CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation in intestinal inflammation
-
(2001)
J Exp Med
, vol.193
, pp. 471-481
-
-
Suzuki, A.1
Hanada, T.2
Misuyama, K.3
Yoshida, T.4
Kamizono, S.5
Hoshino, T.6
Kubo, M.7
Yamashita, A.8
Okabe, M.9
Takeda, K.10
Akira, S.11
Matsumoto, S.12
Toyonaga, A.13
Sata, M.14
Yoshimura, A.15
-
13
-
-
0034465943
-
Interleukin 18 is a potent proliferative factor for intestinal mucosalymphocytes in Crohn's disease
-
(2000)
Gastroenterology
, vol.119
, pp. 1514-1523
-
-
Kanai, T.1
Watanabe, M.2
Okazawa, A.3
Nakamaru, K.4
Okamoto, M.5
Naganuma, M.6
Ishii, H.7
Ikeda, M.8
Kurimoto, M.9
Hibi, T.10
-
15
-
-
0029130042
-
Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR)
-
(1995)
Clin Exp Immunol
, vol.101
, pp. 428-435
-
-
Niessner, M.1
Volk, B.A.2
-
16
-
-
0031057872
-
Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease
-
(1997)
Am J Pathol
, vol.150
, pp. 823-832
-
-
Parronchi, P.1
Romagnani, P.2
Annunziato, F.3
Sampognaro, S.4
Becchio, A.5
Giannarini, L.6
Maggi, E.7
Pupilli, C.8
Tonelli, F.9
Romagnani, S.10
-
17
-
-
0033152023
-
IL-18 a novel immunoregulatory cytokine is up-regulated in Crohn's disease: Expression and localization in intestinal mucosal cells
-
(1999)
J Immunol
, vol.162
, pp. 6829-6835
-
-
Pizarro, T.T.1
Michie, M.H.2
Bentz, M.3
Woraratanadharm, J.4
Smith, M.F.J.5
Foley, E.6
Moskaluk, C.A.7
Bickston, S.J.8
Cominelli, F.9
-
20
-
-
0034795561
-
Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production
-
(2001)
Am J Physiol
, vol.281
, pp. R1264-R1273
-
-
Siegmund, B.1
Fantuzzi, G.2
Rieder, F.3
Gamboni-Robertson, F.4
Lehr, H.A.5
Hartmann, G.6
Dinarello, C.A.7
Endres, S.8
Eigler, A.9
-
21
-
-
0035210979
-
Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice
-
(2001)
Gastroenterology
, vol.121
, pp. 1372-1379
-
-
Ten Hove, T.1
Corbaz, A.2
Amitai, H.3
Aloni, S.4
Belzer, I.5
Graber, P.6
Drillenburg, P.7
Van Deventer, S.J.8
Chvatchko, Y.9
Te Velde, A.A.10
-
24
-
-
0020608619
-
T cell responses induced by the parenteral injection of antigen-modified syngeneic cells. I. Induction, characterization, and regulation of antigen-specific T helper cells involved in delayed-type hypersensitivity responses
-
(1983)
J Immunol
, vol.131
, pp. 77-85
-
-
Miller, S.D.1
Butler, L.D.2
-
26
-
-
0035193261
-
Adenosine kinase inhibitor GP515 improves experimental colitis in mice
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 99-105
-
-
Siegmund, B.1
Rieder, F.2
Albrich, S.3
Wolf, K.4
Bidlingmaier, C.5
Firestein, G.S.6
Boyle, D.7
Lehr, H.A.8
Loher, F.9
Hartmann, G.10
Endres, S.11
Eigler, A.12
-
28
-
-
18344410191
-
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo
-
(2000)
Nat Med
, vol.6
, pp. 583-588
-
-
Atreya, R.1
Mudter, J.2
Finotto, S.3
Mullberg, J.4
Jostock, T.5
Wirtz, S.6
Schutz, M.7
Bartsch, B.8
Holtmann, M.9
Becker, C.10
Strand, D.11
Czaja, J.12
Schlaak, J.F.13
Lehr, H.A.14
Autschbach, F.15
Schurmann, G.16
Nishimoto, N.17
Yoshizaki, K.18
Ito, H.19
Kishimoto, T.20
Galle, P.R.21
Rose-John, S.22
Neurath, M.F.23
more..
-
30
-
-
0035015397
-
Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure
-
(2001)
J Clin Invest
, vol.107
, pp. 1145-1152
-
-
Melnikov, V.Y.1
Ecder, T.2
Fantuzzi, G.3
Siegmund, B.4
Lucia, M.S.5
Dinarello, C.A.6
Schrier, R.W.7
Edelstein, C.L.8
-
34
-
-
0031444188
-
Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13850-13855
-
-
Zhou, Y.J.1
Hanson, E.P.2
Chen, Y.Q.3
Magnuson, K.4
Chen, M.5
Swann, P.G.6
Wange, R.L.7
Changelian, P.S.8
O'Shea, J.J.9
-
38
-
-
0033957727
-
Specific type IV phosphodiesterase inhibitor rolipram mitigates experimental colitis in mice
-
(2000)
J Pharmacol Exp Ther
, vol.292
, pp. 22-30
-
-
Hartmann, G.1
Bidlingmaier, C.2
Siegmund, B.3
Albrich, S.4
Schulze, J.5
Tschoep, K.6
Eigler, A.7
Lehr, H.A.8
Endres, S.9
-
42
-
-
0009912839
-
Phenotypic abnormalities in macrophages from leptin-deficient, obese mice
-
(1999)
Am J Physiol
, vol.276
, pp. C386-C394
-
-
Lee, F.Y.1
Li, Y.2
Yang, E.K.3
Yang, S.Q.4
Lin, H.Z.5
Trush, M.A.6
Dannenberg, A.J.7
Diehl, A.M.8
-
43
-
-
0035873418
-
Requirement for leptin in the induction and progression of autoimmune encephalomyelitis
-
(2001)
J Immunol
, vol.166
, pp. 5909-5916
-
-
Matarese, G.1
Di Giacomo, A.2
Sanna, V.3
Lord, G.M.4
Howard, J.K.5
Di Tuoro, A.6
Bloom, S.R.7
Lechler, R.8
Zappacosta, S.9
Fontana, S.10
-
44
-
-
0034998907
-
Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males
-
(2001)
Eur J Immunol
, vol.31
, pp. 1324-1332
-
-
Matarese, G.1
Sanna, V.2
Di Giacomo, A.3
Lord, G.M.4
Howard, J.K.5
Bloom, S.R.6
Lechler, R.I.7
Fontana, S.8
Zappacosta, S.9
-
53
-
-
0031821859
-
Anti-inflammatory effect of interleukin-10 in rabbit immune complex-induced colitis
-
(1998)
Scand J Gastroenterol
, vol.33
, pp. 754-758
-
-
Grool, T.A.1
Van Dullemen, H.2
Meenan, J.3
Koster, F.4
Ten Kate, F.J.5
Lebeaut, A.6
Tytgat, G.N.7
Van Deventer, S.J.8
-
54
-
-
0034714188
-
Treatment of murine colitis by Lactococcus lactis secreting interleukin-10
-
(2000)
Science
, vol.289
, pp. 1352-1355
-
-
Steidler, L.1
Hans, W.2
Schotte, L.3
Neirynck, S.4
Obermeier, F.5
Falk, W.6
Fiers, W.7
Remaut, E.8
-
57
-
-
0034659767
-
Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: Lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine
-
(2000)
J Immunol
, vol.164
, pp. 6303-6312
-
-
Andres, P.G.1
Beck, P.L.2
Mizoguchi, E.3
Mizoguchi, A.4
Bhan, A.K.5
Dawson, T.6
Kuziel, W.A.7
Maeda, N.8
MacDermott, R.P.9
Podolsky, D.K.10
Reinecker, H.C.11
-
61
-
-
0034235440
-
Activation of natural killer T cells by α-galactosylceramide in the presence of CD1d provides protection against colitis in mice
-
(2000)
Gastroenterology
, vol.119
, pp. 119-128
-
-
Saubermann, L.J.1
Beck, P.2
De Jong, Y.P.3
Pitman, R.S.4
Ryan, M.S.5
Kim, H.S.6
Exley, M.7
Snapper, S.8
Balk, S.P.9
Hagen, S.J.10
Kanauchi, O.11
Motoki, K.12
Sakai, T.13
Terhorst, C.14
Koezuka, Y.15
Podoisky, D.K.16
Blumberg, R.S.17
-
62
-
-
0030240383
-
Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha- and beta-chains of its receptor
-
(1996)
J Immunol
, vol.157
, pp. 1935-1943
-
-
Novelli, F.1
Bernabei, P.2
Ozmen, L.3
Rigamonti, L.4
Allione, A.5
Pestka, S.6
Garotta, G.7
Forni, G.8
-
65
-
-
0033214903
-
Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3
-
(1999)
Genes Dev
, vol.13
, pp. 2604-2616
-
-
Chapman, R.S.1
Lourenco, P.C.2
Tonner, E.3
Flint, D.J.4
Selbert, S.5
Takeda, K.6
Akira, S.7
Clarke, A.R.8
Watson, C.J.9
|