Sustained high levels of serum leptin rather than IL-6 observed in patients with postpartum thyroiditis during their first postpartum year

Endocrine

Volumn 47, Issue 2, 2014, Pages 512-518

  Guo, Huiling ^a   Liu, Xiu ^a   Li, Chenyang ^b   Li, Yushu ^a   Sang, Miao ^a   Shan, Zhongyan ^a   Teng, Weiping ^a   Guan, Haixia ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Shenyang Women Hospital   (China)

Author keywords

Autoimmune; Interleukin 6; Leptin; Postpartum thyroiditis

Indexed keywords

INTERLEUKIN 6; LEPTIN; THYROID ANTIBODY; THYROTROPIN; THYROXINE;

ADULT; ARTICLE; BODY MASS; CHINESE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HORMONE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; POSTPARTUM THYROIDITIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; RADIOIMMUNOASSAY; RETROSPECTIVE STUDY; BLOOD; PUERPERIUM;

ADULT; FEMALE; HUMANS; INTERLEUKIN-6; LEPTIN; POSTPARTUM PERIOD; POSTPARTUM THYROIDITIS; RETROSPECTIVE STUDIES;

EID: 84911002430     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-014-0176-3     Document Type: Article

References (36)

1. N. Amino, H. Mori, Y. Iwatani, O. Tanizawa, M. Kawashima, I. Tsuge, K. Ibaragi, Y. Kumahara, K. Miyai, High prevalence of transient post-partum thyrotoxicosis and hypothyroidism. N. Engl. J. Med. 306, 849–852 (1982)
2. A. Stagnaro-Green, Postpartum thyroiditis. Best Pract. Res. Clin. Endocrinol. Metab. 18, 303–316 (2004)
3. A.F. Muller, H.A. Drexhage, A. Berghout, Postpartum thyroiditis and autoimmune thyroiditis in women of 1119 childbearing age: recent insights and consequences for antenatal and postnatal care. Endocr. Rev. 22, 605–630 (2001)
4. H. Guan, C. Li, Y. Li, C. Fan, Y. Teng, Z. Shan, W. Teng, High iodine intake is a risk factor of post-partum thyroiditis: result of a survey from Shenyang, China. J. Endocrinol. Invest. 28, 876–881 (2005)
5. J.L. Kuijpens, M. De Hann-Meulman, H.L. Vader, V.J. Pop, W.M. Wiersinga, H.A. Drexhage, Cell-mediated immunity and postpartum thyroid dysfunction: a possibility for the prediction of disease? J. Clin. Endocrinol. Metab. 83, 1959–1966 (1998)
6. A. Stagnaro-Green, S.H. Roman, R.H. Cobin, el-Harazy E, Wallenstein S, Davies TF: a prospective study of lymphocyte-initiated immunosuppression in normal pregnancy: evidence of a T-cell etiology for postpartum thyroid dysfunction. J. Clin. Endocrinol. Metab. 74, 645–653 (1992)
7. Y. Zhang, R. Proenca, M. Maffei, M. Barone, L. Leopold, J.M. Friedman, Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425–432 (1994)
8. F. Zhang, M.B. Basinski, J.M. Beals, S.L. Briggs, L.M. Churgay, D.K. Clawson, R.D. DiMarchi, T.C. Furman, J.E. Hale, H.M. Hsiung, B.E. Schoner, D.P. Smith, X.Y. Zhang, J.P. Wery, R.W. Schevitz, Crystal structure of the obese protein leptin-E 100. Nature 387, 206–209 (1997)
9. C.S. Mantzoros, S.J. Moschos, Leptin: in search of role(s) in human physiology and pathophysiology. Clin. Endocrinol. (Oxf). 49, 551–567 (1998)
10. G.M. Lord, G. Matarese, J.K. Howard, R.J. Baker, S.R. Bloom, R.I. Lechler, Leptin modulates the T-cell immune responses and reverses starvation-induced immunosuppression. Nature 394, 897–901 (1998)
11. S. Barbosa Vde, J. Rêgo, N. Antônio da Silva, Possible role of adipokines in systemic lupus erythematosus and rheumatoid arthritis. Rev. Bras. Reumatol. 52, 271–287 (2012)
12. A.P. Weetman, R. Bright-Thomas, M. Freeman, Regulation of interleukin-6 release by human thyrocytes. J. Endocrinol. 127, 357–361 (1990)
13. L. Bartalena, S. Brogioni, L. Grasso, E. Martino, Increased serum interleukin-6 concentration in patients with subacute thyroiditis: relationship with concomitant changes in serum T4-binding globulin concentration. J. Endocrinol. Invest. 16, 213–218 (1993)
14. L. Bartalena, L. Grasso, S. Brogioni, F. Aghini-lombardi, L.E. Braverman, E. Martino, Serum interleukin-6 in amiodarone-induced thyrotoxicosis. J. Clin. Endocrinol. Metab. 78, 423–427 (1994)
15. M. Salvi, G. Girasole, M. Pedrazzoni, M. Passeri, N. Giuliani, R. Minelli, Increased serum concentrations of Interleukin-6 (IL-6) and soluble IL-6 receptor in patients with Graves’ disease. J. Clin. Endocrinol. Metab. 81, 2976–2979 (1996)
16. I. Celik, S. Akalin, T. Erbas, Serum levels of interleukin 6 and tumor necrosis factor-a in hyperthyroid patients before and after propylthiouracil treatment. Eur. J. Endocrinol. 132, 668–672 (1995)
17. D. Teng, C. Li, Y. Teng, Y. Ouyang, Y. Li, W. Teng, Dynamic changes of IgG subtypes of thyroid peroxidase antibody in patients with postpartum thyroiditis. Gynecol. Obstet. Invest. 69, 24–29 (2010)
18. X. Shi, C. Li, Y. Li, H. Guan, C. Fan, Y. Teng, Y. Ouyang, Z. Shan, W. Teng, Circulating lymphocyte subsets and regulatory T cells in patients with postpartum thyroiditis during the first postpartum year. Clin. Exp. Med. 9, 263–267 (2009)
19. L. Siemińska, C. Wojciechowska, B. Kos-Kudła, B. Marek, D. Kajdaniuk, M. Nowak, J. Głogowska-Szelag, W. Foltyn, J. Strzelczyk, Serum concentrations of leptin, adiponectin, and interleukin-6 in postmenopausal women with Hashimoto’s thyroiditis. Endokrynol. Pol. 61, 112–116 (2010)
20. P.F. Teixeira, M.D. Cabral, N.A. Silva, D.V. Soares, V.B. Braulio, A.P. Couto, J.L. Henriques, A.J. Costa, A. Buescu, M. Vaisman, Serum leptin in overt and subclinical hypothyroidism: effect of levothyroxine treatment and relationship to menopausal status and body composition. Thyroid. 19, 443–450 (2009)
21. R. Gunaydin, T. Kaya, A. Atay, N. Olmez, A. Hur, M. Koseoglu, Serum leptin levels in rheumatoid arthritis and relationship with disease activity. South. Med. J. 99, 1078–1083 (2006)
22. D.A. Fraser, J. Thoen, J.E. Reseland, O. Forre, J. Kjeldsen-Kragh, Decreased CD4+ lymphocyte activation and increased interleukin-4 production in peripheral blood of rheumatoid arthritis patients after acute starvation. Clin. Rheumatol. 18, 394–401 (1999)
23. G. Mazziotti, A.B. Parkes, M. Lage, L.D. Premawardhana, F.F. Casanueva, J.H. Lazarus, High leptin levels in women developing postpartum thyroiditis. Clin. Endocrinol. (Oxf). 60, 208–213 (2004)
24. J.S. Flier, M. Harris, A.N. Hollenberg, Leptin, nutrition, and the thyroid: the why, the wherefore, and the wiring. J. Clin. Invest. 105, 859–861 (2000)
25. A. Oge, F. Bayraktar, F. Saygili, E. Guney, S. Demir, TSH influences serum leptin levels independent of thyroid hormones in hypothyroid and hyperthyroid patients. Endocr. J. 52, 213–217 (2005)
26. M.J. Diekman, J.A. Romijn, E. Endert, H. Sauerwein, W.M. Wiersinga, Thyroid hormones modulate serum leptin levels: observations in thyrotoxic and hypothyroid women. Thyroid. 12, 1081–1086 (1998)
27. U. Leonhardt, U. Ritzel, G. Schäfer, W. Becker, G. Ramadori, Serum leptin levels in hypo and hyperthyroidism. J. Endocrinol. 157, 75–79 (1998)
28. S. Corbetta, P. Enafaro, S. Gianbona, L. Persani, W.F. Blum, P. Beck-Peccoz, Lack of effects of circulating thyroid hormone level on serum leptin concentrations. Eur. J. Endocrinol. 137, 659–663 (1997)
29. M. Owecki, Z. El Ali, R. Wasko, E. Nikisch, A. Dziubandowska, A. Sulikowska, J. Sowiński, Circulating leptin levels are not influenced by thyroid status in hypothyroid and euthyroid women. Neuro Endocrinol. Lett. 28, 417–421 (2007)
30. J.H. Lazarus, A. Kokandi, Thyroid disease in relation to pregnancy: a decade of change. Clin. Endocrinol. (Oxf). 53, 265–278 (2000)
31. A. Kokandi, A. Parkes, L. Premawardhana, R. John, J. Lazarus, Association of postpartum thyroid dysfunction with antepartum hormonal and immunological changes. J. Clin. Endocrinol. Metab. 88, 1126–1132 (2003)
32. G. Matarese, A. La Cava, V. Sanna, G.M. Lord, R.I. Lechler, S. Fontana, S. Zappacosta, Balancing susceptibility to infection and autoimmunity: a role for leptin? Trends Immunol. 23, 182–187 (2002)
33. G. Matarese, V. Sanna, A. Di Giacomo, G.M. Lord, J.K. Howard, S.R. Bloom, R.I. Lechler, S. Fontana, S. Zappacosta, Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males. Eur. J. Immunol. 31, 1324–1332 (2001)
34. V. Sanna, A. Di Giacomo, A. La Cava, R.I. Lechler, S. Fontana, S. Zappacosta, G. Matarese, Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses. J. Clin. Invest. 111, 241–250 (2003)
35. L. Ahmad, A. Parkes, J. Lazarus, L. Bartalena, E. Martino, E. Diamond, A. Stagnaro-Green, Interleukin-6 levels are not increased in women with postpartum thyroid dysfunction. Thyroid. 8, 371–375 (1998)
36. A.B. Pedro, J.H. Romaldini, K. Takei, Changes of serum cytokines in hyperthyroid Graves’ disease patients at diagnosis and during methimazole treatment. Neuroimmunomodulation 18, 45–51 (2011)