Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

Journal of Clinical Investigation

Volumn 110, Issue 8, 2002, Pages 1093-1103

  Sadaf Farooqi, I ^a   Matarese, Giuseppe ^b   Lord, Graham M ^c   Keogh, Julia M ^a   Lawrence, Elizabeth ^d   Agwu, Chizo ^e   Sanna, Veronica ^b   Jebb, Susan A ^f   Perna, Francesco ^g   Fontana, Silvia ^b   Lechler, Robert I ^c   Depaoli, Alex M ^d   O'Rahilly, Stephen ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b CNR   (Italy)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

^d AMGEN INC   (United States)

^e SANDWELL GENERAL HOSPITAL   (United Kingdom)

^f MEDICAL RESEARCH COUNCIL   (United Kingdom)

^g UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT LEPTIN;

ARTICLE; BODY COMPOSITION; BODY FAT; BODY MASS; CASE REPORT; CHILD; CONGENITAL LEPTIN DEFICIENCY; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HORMONE DEFICIENCY; HUMAN; HUMAN CELL; HYPERINSULINEMIA; HYPERLIPIDEMIA; IMMUNE SYSTEM; LYMPHOCYTE FUNCTION; METABOLIC PARAMETERS; OBESITY; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; TREATMENT OUTCOME; WEIGHT REDUCTION;

EID: 0036800760     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200215693     Document Type: Article

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