Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats

Autoimmunity

Volumn 44, Issue 2, 2011, Pages 137-148

  Kruger, Annie J ^a   Yang, Chaoxing ^a   Lipson, Kathryn L ^b   Pino, Stephen C ^a   Leif, Jean H ^a   Hogan, Christopher M ^c   Whalen, Barbara J ^c   Guberski, Dennis L ^c   Lee, Young ^d   Unger, Roger H ^d   Greiner, Dale L ^a   Rossini, Aldo A ^a   Bortell, Rita ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b WESTERN NEW ENGLAND UNIVERSITY   (United States)

^c Biomedical Research Models Inc   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

BB rat; islet transplantation; leptin; Type 1 diabetes; virus

Indexed keywords

ADENOVIRUS VECTOR; INSULIN; LEPTIN; POLYINOSINIC POLYCYTIDYLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL DESTRUCTION; CONTROLLED STUDY; DIABETIC KETOACIDOSIS; DRUG ACTIVITY; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; HYPERLEPTINEMIA; INNATE IMMUNITY; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; ISOGRAFT; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; RAT; RECURRENT DISEASE; REMISSION; SINGLE DRUG DOSE; SURVIVAL RATE;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETIC KETOACIDOSIS; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; LEPTIN; PARVOVIRIDAE INFECTIONS; PARVOVIRUS; POLY I-C; RATS; RATS, INBRED BB; TREATMENT OUTCOME;

EID: 79551569614     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.3109/08916934.2010.482116     Document Type: Article

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