-
1
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky DK. Inflammatory bowel disease. N Engl JMed 2002;347:417-429
-
(2002)
N Engl JMed
, vol.347
, pp. 417-429
-
-
Podolsky, D.K.1
-
2
-
-
0026432216
-
Inflammatory bowel disease (1
-
Podolsky DK. Inflammatory bowel disease (1). N Engl JMed 1991;325:928-937
-
(1991)
N Engl JMed
, vol.325
, pp. 928-937
-
-
Podolsky, D.K.1
-
3
-
-
85045801945
-
Controlled trial of bowel rest and nutritional support in themanagement of Crohn's disease
-
Greenberg GR, Fleming CR, Jeejeebhoy KN, et al. Controlled trial of bowel rest and nutritional support in themanagement of Crohn's disease. Am J Clin Nutr 1989;49:573-579
-
(1989)
Am J Clin Nutr
, vol.49
, pp. 573-579
-
-
Greenberg, G.R.1
Fleming, C.R.2
Jeejeebhoy, K.N.3
-
4
-
-
0031568001
-
Induction and prevention of colonic inflammation in IL- 2-deficient mice
-
Ehrhardt RO, Ludviksson BR, Gray B, et al. Induction and prevention of colonic inflammation in IL- 2-deficient mice. J Immunol 1997;158:566-573
-
(1997)
J Immunol
, vol.158
, pp. 566-573
-
-
Ehrhardt, R.O.1
Ludviksson, B.R.2
Gray, B.3
-
5
-
-
0024725379
-
Inflammatory bowel disease: Nutritional implications and treatment
-
Silk DB, Payne-James J. Inflammatory bowel disease: Nutritional implications and treatment. Proc Nutr Soc 1989;48:355-361
-
(1989)
Proc Nutr Soc
, vol.48
, pp. 355-361
-
-
Silk, D.B.1
Payne-James, J.2
-
6
-
-
0028130092
-
Mechanisms of decreased food intake during weight loss in adult Crohn's disease patients without obvious malabsorption
-
Rigaud D, Angel LA, Cerf M, et al. Mechanisms of decreased food intake during weight loss in adult Crohn's disease patients without obvious malabsorption. Am J Clin Nutr 1994;60: 775-781
-
(1994)
Am J Clin Nutr
, vol.60
, pp. 775-781
-
-
Rigaud, D.1
Angel, L.A.2
Cerf, M.3
-
8
-
-
0029552652
-
Genetic and spontaneous models of inflammatory bowel disease in rodents: Evidence for abnormalities inmucosal immune regulation
-
Powrie F, Leach MW. Genetic and spontaneous models of inflammatory bowel disease in rodents: Evidence for abnormalities inmucosal immune regulation.Ther Immunol 1995;2:115-123
-
(1995)
Ther Immunol
, vol.2
, pp. 115-123
-
-
Powrie, F.1
Leach, M.W.2
-
9
-
-
0027922467
-
Spontaneous development of inflammatory bowel disease in t cell receptormutant mice
-
Mombaerts P,Mizoguchi E, GrusbyMJ, et al. Spontaneous development of inflammatory bowel disease in T cell receptormutant mice. Cell 1993;75:274-282
-
(1993)
Cell
, vol.75
, pp. 274-282
-
-
Mombaerts, P.1
Mizoguchi, E.2
Grusby, M.J.3
-
10
-
-
0029102210
-
Severe colitis in mice with aberrant thymic selection
-
Hollander GA, Simpson SJ,Mizoguchi E, et al. Severe colitis in mice with aberrant thymic selection. Immunity 1995;3:27-38
-
(1995)
Immunity
, vol.3
, pp. 27-38
-
-
Hollander, G.A.1
Simpson, S.J.2
Mizoguchi, E.3
-
12
-
-
33747830880
-
Towards a pro-inflammatory and immunomodulatory emerging role of leptin
-
Oxford
-
Otero M, Lago R, Gomez R, et al. Towards a pro-inflammatory and immunomodulatory emerging role of leptin. Rheumatology (Oxford) 2006;45:944-950
-
(2006)
Rheumatology
, vol.45
, pp. 944-950
-
-
Otero, M.1
Lago, R.2
Gomez, R.3
-
13
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue see comments erratum appears in nature 1995mar 30;374(6521 :479
-
Zhang Y. Positional cloning of the mouse obese gene and its human homologue. [see comments erratum appears in Nature 1995Mar 30;374(6521):479]. Nature 1994;372:425-432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
-
15
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
AhimaRS, Prabakaran D,MantzorosC, et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996;382:250-252
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
-
16
-
-
0030467446
-
The OB protein (leptin) pathway - A link between adipose tissue mass and central neural networks
-
Campfield LA, Smith FJ, Burn P. The OB protein (leptin) pathway - A link between adipose tissue mass and central neural networks. HormMetab Res 1996;28:619-632
-
(1996)
HormMetab Res
, vol.28
, pp. 619-632
-
-
Campfield, L.A.1
Smith, F.J.2
Burn, P.3
-
17
-
-
0030007116
-
Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction
-
Cioffi JA, Shafer AW, Zupancic TJ, et al. Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction. NatMed 1996;2:585-589
-
(1996)
NatMed
, vol.2
, pp. 585-589
-
-
Cioffi, J.A.1
Shafer, A.W.2
Zupancic, T.J.3
-
18
-
-
0029863684
-
Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters
-
Grunfeld C, Zhao C, Fuller J, et al. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. J Clin Invest 1996;97:2152-2157
-
(1996)
J Clin Invest
, vol.97
, pp. 2152-2157
-
-
Grunfeld, C.1
Zhao, C.2
Fuller, J.3
-
19
-
-
84893028178
-
In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide
-
Ning W, Dantzer R, Freund GG, et al. In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide. J Immunol 1998;160: 1393-1401
-
(1998)
J Immunol
, vol.160
, pp. 1393-1401
-
-
Ning, W.1
Dantzer, R.2
Freund, G.G.3
-
21
-
-
84893124870
-
Tumor necrosis factor increases serumleptin levels in humans
-
Kohl B, Zumbach MS, Borcea V, et al. Tumor necrosis factor increases serumleptin levels in humans. Diabetes Care 1997;20:1880-1886
-
(1997)
Diabetes Care
, vol.20
, pp. 1880-1886
-
-
Kohl, B.1
Zumbach, M.S.2
Borcea, V.3
-
22
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese genesee comments
-
Halaas JL, Friedman JM, Chait BT, et al. Weight-reducing effects of the plasma protein encoded by the obese gene. [see comments.]. Science 1995;269(5223):543-546
-
(1995)
Science
, vol.269
, Issue.5223
, pp. 543-546
-
-
Halaas, J.L.1
Friedman, J.M.2
Chait, B.T.3
-
23
-
-
0033930048
-
Leptin secretion and leptin receptor in the human stomach
-
Sobhani I, Bado A, Vissuzaine C, et al. Leptin secretion and leptin receptor in the human stomach. Gut 2000;47:178-183
-
(2000)
Gut
, vol.47
, pp. 178-183
-
-
Sobhani, I.1
Bado, A.2
Vissuzaine, C.3
-
24
-
-
0036155743
-
Leptin regulates GH gene expression and secretion and nitric oxide production in pig pituitary cells
-
BarattaM, Saleri R,Mainardi GL, et al. Leptin regulates GH gene expression and secretion and nitric oxide production in pig pituitary cells. Endocrinology 2002;143:551-557
-
(2002)
Endocrinology
, vol.143
, pp. 551-557
-
-
Baratta, M.1
Saleri, R.2
Mainardi, G.L.3
-
25
-
-
84877127863
-
Leptin-mediated regulation ofmt1-mmp localization is kif1b dependent and enhances gastric cancer cell invasion
-
Dong Z, Xu X, Du L, et al. Leptin-mediated regulation ofMT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion. Carcinogenesis 2013;34(5):974-983
-
(2013)
Carcinogenesis
, vol.34
, Issue.5
, pp. 974-983
-
-
Dong, Z.1
Xu, X.2
Du, L.3
-
26
-
-
78650807538
-
Puberty is delayed in male mice with dextran sodium sulfate colitis out of proportion to changes in food intake, body weight, and serum levels of leptin
-
Deboer MD, Li Y. Puberty is delayed in male mice with dextran sodium sulfate colitis out of proportion to changes in food intake, body weight, and serum levels of leptin. Pediatr Res 2011;69: 34-39
-
(2011)
Pediatr Res
, vol.69
, pp. 34-39
-
-
Deboer, M.D.1
Li, Y.2
-
27
-
-
0031768795
-
Elevated plasma leptin concentrations in early stages of experimental intestinal inflammation in rats
-
BarbierM, Cherbut C, Aube AC, et al. Elevated plasma leptin concentrations in early stages of experimental intestinal inflammation in rats. Gut 1998;43:783-790
-
(1998)
Gut
, vol.43
, pp. 783-790
-
-
Barbier, M.1
Cherbut, C.2
Aube, A.C.3
-
28
-
-
0031014348
-
Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels
-
Weigle DS, Duell PB, Connor WE, et al. Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels. J Clin EndocrinolMetab 1997;82:561-565
-
(1997)
J Clin EndocrinolMetab
, vol.82
, pp. 561-565
-
-
Weigle, D.S.1
Duell, P.B.2
Connor, W.E.3
-
29
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl JMed 1996;334:292-295
-
(1996)
N Engl JMed
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
-
30
-
-
0036257317
-
The leptin defense against wasting is abolished in the IL-2- deficient mousemodel of inflammatory bowel disease
-
Gaetke LM, Oz HS, de Villiers WJ, et al.The leptin defense against wasting is abolished in the IL-2- deficient mousemodel of inflammatory bowel disease. J Nutr 2002;132:893-896
-
(2002)
J Nutr
, vol.132
, pp. 893-896
-
-
Gaetke, L.M.1
Oz, H.S.2
De Villiers, W.J.3
-
31
-
-
2342564361
-
Leptin levels in the acute stage of ulcerative colitis
-
TuzunA,Uygun A, Yesilova Z, et al. Leptin levels in the acute stage of ulcerative colitis. JGastroenterol Hepatol 2004;19:429-432
-
(2004)
JGastroenterol Hepatol
, vol.19
, pp. 429-432
-
-
Tuzun, A.1
Uygun, A.2
Yesilova, Z.3
-
32
-
-
33645023150
-
Circulating levels of leptin, adiponectin, resistin, and ghrelin in inflammatory bowel disease
-
Karmiris K, Koutroubakis IE, Xidakis C, et al. Circulating levels of leptin, adiponectin, resistin, and ghrelin in inflammatory bowel disease. Inflamm Bowel Dis 2006;12:100-105
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 100-105
-
-
Karmiris, K.1
Koutroubakis, I.E.2
Xidakis, C.3
-
33
-
-
49549091196
-
Leptin adiponectin resistin and ghrelin-implications for inflammatory bowel disease
-
Karmiris K, Koutroubakis IE, Kouroumalis EA. Leptin, adiponectin, resistin, and ghrelin-implications for inflammatory bowel disease.Mol Nutr Food Res 2008;52:855-866
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 855-866
-
-
Karmiris, K.1
Koutroubakis, I.E.2
Kouroumalis, E.A.3
-
34
-
-
84870613773
-
Expression and release of leptin and proinflammatory cytokines in patients with ulcerative colitis and infectious diarrhea
-
Biesiada G, Czepiel J, Ptak-Belowska A, et al. Expression and release of leptin and proinflammatory cytokines in patients with ulcerative colitis and infectious diarrhea. J Physiol Pharmacol 2012;63:471-481
-
(2012)
J Physiol Pharmacol
, vol.63
, pp. 471-481
-
-
Biesiada, G.1
Czepiel, J.2
Ptak-Belowska, A.3
-
36
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, et al. Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. NatMed 1995;1:1155-1161
-
(1995)
NatMed
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
-
37
-
-
0033946980
-
Photoperiodic versus metabolic signals as determinants of seasonal anestrus in themare
-
Fitzgerald BP, McManus CJ. Photoperiodic versus metabolic signals as determinants of seasonal anestrus in themare. Biol Reprod 2000;63:335-340
-
(2000)
Biol Reprod
, vol.63
, pp. 335-340
-
-
Fitzgerald, B.P.1
Mcmanus, C.J.2
-
38
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factoralpha in human obesity and insulin resistance
-
Hotamisligil GS, Arner P, Caro JF, et al. Increased adipose tissue expression of tumor necrosis factoralpha in human obesity and insulin resistance. J Clin Invest 1995;95:2409-2415
-
(1995)
J Clin Invest
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
-
39
-
-
0028236232
-
Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease
-
Breese EJ,MichieCA,Nicholls SW, et al. Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 1994;106:1455-1466
-
(1994)
Gastroenterology
, vol.106
, pp. 1455-1466
-
-
Breese, E.J.1
Michie, C.A.2
Nicholls, S.W.3
-
40
-
-
0030451949
-
Increased production of tumour necrosis factor-apha interleukin-1 beta, and interleukin-6 by morphologically normal intestinal biopsies from patients with Crohn's disease
-
Reimund JM, Wittersheim C, Dumont S, et al. Increased production of tumour necrosis factor-apha interleukin-1 beta, and interleukin-6 by morphologically normal intestinal biopsies from patients with Crohn's disease. Gut 1996;39:684-689
-
(1996)
Gut
, vol.39
, pp. 684-689
-
-
Reimund, J.M.1
Wittersheim, C.2
Dumont, S.3
-
41
-
-
0028519015
-
Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
-
Powrie F, Leach MW, Mauze S, et al. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity 1994;1:553-562
-
(1994)
Immunity
, vol.1
, pp. 553-562
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
-
42
-
-
0031454125
-
Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes
-
Kirchgessner TG, Uysal KT, Wiesbrock SM, et al. Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. J Clin Invest 1997;100:2777-2782
-
(1997)
J Clin Invest
, vol.100
, pp. 2777-2782
-
-
Kirchgessner, T.G.1
Uysal, K.T.2
Wiesbrock, S.M.3
-
43
-
-
0344739789
-
Overexpression of leptinmRNAinmesenteric adipose tissue in inflammatory bowel diseases
-
BarbierM,Vidal H,Desreumaux P, et al. Overexpression of leptinmRNAinmesenteric adipose tissue in inflammatory bowel diseases. Gastroenterol Clin Biol 2003;27:987-991
-
(2003)
Gastroenterol Clin Biol
, vol.27
, pp. 987-991
-
-
Barbier, M.1
Vidal, H.2
Desreumaux, P.3
-
44
-
-
3042704740
-
Colonic leptin: Source of a novel proinflammatory cytokine involved in IBD
-
Sitaraman S, Liu X, Charrier L, et al. Colonic leptin: Source of a novel proinflammatory cytokine involved in IBD. FASEB J 2004;18:696-698
-
(2004)
FASEB J
, vol.18
, pp. 696-698
-
-
Sitaraman, S.1
Liu, X.2
Charrier, L.3
-
45
-
-
79955558382
-
Assessment of nutritional status and serum leptin in children with inflammatory bowel disease
-
Aurangzeb B, Leach ST, Lemberg DA, Day AS. Assessment of nutritional status and serum leptin in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2011;52:536-541
-
(2011)
J Pediatr Gastroenterol Nutr
, vol.52
, pp. 536-541
-
-
Aurangzeb, B.1
Leach, S.T.2
Lemberg, D.A.3
Day, A.S.4
-
46
-
-
21244432426
-
Impact of infliximab on serumleptin levels in patientswith Crohn's disease
-
FranchimontD, Roland S,Gustot T, et al. Impact of infliximab on serumleptin levels in patientswith Crohn's disease. J Clin EndocrinolMetab 2005;90:3510-3516
-
(2005)
J Clin EndocrinolMetab
, vol.90
, pp. 3510-3516
-
-
Franchimont, D.1
Roland, S.2
Gustot, T.3
-
47
-
-
0031926272
-
Plasma leptin in chronic inflammatory bowel disease and HIV: Implications for the pathogenesis of anorexia and weight loss
-
Ballinger A, Kelly P, Hallyburton E, et al. Plasma leptin in chronic inflammatory bowel disease and HIV: Implications for the pathogenesis of anorexia and weight loss. Clin Sci (Lond) 1998;94:479-483
-
(1998)
Clin Sci (Lond
, vol.94
, pp. 479-483
-
-
Ballinger, A.1
Kelly, P.2
Hallyburton, E.3
-
48
-
-
0032572722
-
Leptinmodulates the T-cell immune response and reverses starvation-induced immunosuppression
-
Lord GM,Matarese G, Howard JK, et al. Leptinmodulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 1998;394:897-901
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
-
49
-
-
33747799996
-
Indirect effects of leptin receptor deficiency on lymphocyte populations and immune response in db/dbmice
-
Palmer G, Aurrand-LionsM, Contassot E, et al. Indirect effects of leptin receptor deficiency on lymphocyte populations and immune response in db/dbmice. J Immunol 2006;177:2899-2907
-
(2006)
J Immunol
, vol.177
, pp. 2899-2907
-
-
Palmer, G.1
Aurrand-Lions, M.2
Contassot, E.3
-
51
-
-
0032741972
-
Leptin protectsmice fromstarvation-induced lymphoid atrophy and increases thymic cellularity in ob/obmice
-
Howard JK, Lord GM,Matarese G, et al. Leptin protectsmice fromstarvation-induced lymphoid atrophy and increases thymic cellularity in ob/obmice. J Clin Invest 1999;104:1051-1059
-
(1999)
J Clin Invest
, vol.104
, pp. 1051-1059
-
-
Howard, J.K.1
Lord, G.M.2
Matarese, G.3
-
52
-
-
0036080142
-
Leptin: A pivotal mediator of intestinal inflammation in mice
-
Siegmund B, Lehr HA, Fantuzzi G. Leptin: A pivotal mediator of intestinal inflammation in mice. Gastroenterology 2002;122:2011-2025
-
(2002)
Gastroenterology
, vol.122
, pp. 2011-2025
-
-
Siegmund, B.1
Lehr, H.A.2
Fantuzzi, G.3
-
53
-
-
0037080196
-
Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis
-
Busso N, So A, Chobaz-Peclat V, et al. Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis. J Immunol. 2002;168:875-882
-
(2002)
J Immunol
, vol.168
, pp. 875-882
-
-
Busso, N.1
So, A.2
Chobaz-Peclat, V.3
-
54
-
-
0030250892
-
A role for leptin and its cognate receptor in hematopoiesis
-
Bennett BD, Solar GP, Yuan JQ, et al. A role for leptin and its cognate receptor in hematopoiesis. Curr Biol 1996;6:1170-1180
-
(1996)
Curr Biol
, vol.6
, pp. 1170-1180
-
-
Bennett, B.D.1
Solar, G.P.2
Yuan, J.Q.3
-
55
-
-
0036697779
-
Leptin inhibits the anti-CD3-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines
-
Lord GM, Matarese G, Howard JK, et al. Leptin inhibits the anti-CD3-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines. J Leuko Biol 2002;72:330-338
-
(2002)
J Leuko Biol
, vol.72
, pp. 330-338
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
-
56
-
-
18944364947
-
Leptin promotes differentiation and survival of human dendritic cells and licenses them for Th1 priming
-
Mattioli B, Straface E, Quaranta MG, et al. Leptin promotes differentiation and survival of human dendritic cells and licenses them for Th1 priming. J Immunol 2005;174:6820-6828
-
(2005)
J Immunol
, vol.174
, pp. 6820-6828
-
-
Mattioli, B.1
Straface, E.2
Quaranta, M.G.3
-
57
-
-
34250730714
-
Leptin induces tissue factor expression in human peripheral blood mononuclear cells a possible link between obesity and cardiovascular risk?
-
Napoleone E, DI Santo A, Amore C, et al. Leptin induces tissue factor expression in human peripheral blood mononuclear cells: A possible link between obesity and cardiovascular risk? J Thromb Haemost 2007;5:1462-1468
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1462-1468
-
-
Napoleone, E.1
Di Santo, A.2
Amore, C.3
-
58
-
-
77949493588
-
Leptin and adiponectin: From energy and metabolic dysbalance to inflammation and autoimmunity
-
Stofkova A. Leptin and adiponectin: From energy and metabolic dysbalance to inflammation and autoimmunity. Endo Regulat 2009;43:157-168
-
(2009)
Endo Regulat
, vol.43
, pp. 157-168
-
-
Stofkova, A.1
-
59
-
-
1642525689
-
Leptin indirectly activates human neutrophils via induction of TNF-alpha
-
Zarkesh-Esfahani H, Pockley AG, Wu Z, et al. Leptin indirectly activates human neutrophils via induction of TNF-alpha. J Immunol 2004;172:1809-1814
-
(2004)
J Immunol
, vol.172
, pp. 1809-1814
-
-
Zarkesh-Esfahani, H.1
Pockley, A.G.2
Wu, Z.3
-
60
-
-
0034628016
-
Human leptin enhances activation and proliferation of human circulating T lymphocytes
-
Martin-Romero C, Santos-Alvarez J, Goberna R, et al. Human leptin enhances activation and proliferation of human circulating T lymphocytes. Cell Immunol 2000;199:15-24
-
(2000)
Cell Immunol
, vol.199
, pp. 15-24
-
-
Martin-Romero, C.1
Santos-Alvarez, J.2
Goberna, R.3
-
61
-
-
38549161031
-
Leptin promotes cell survival and activates Jurkat T lymphocytes by stimulation of mitogen-activated protein kinase
-
Fernandez-Riejos P, Goberna R, Sanchez-Margalet V. Leptin promotes cell survival and activates Jurkat T lymphocytes by stimulation of mitogen-activated protein kinase. Clin Exp Immunol 2008;151:505-518
-
(2008)
Clin Exp Immunol
, vol.151
, pp. 505-518
-
-
Fernandez-Riejos, P.1
Goberna, R.2
Sanchez-Margalet, V.3
-
62
-
-
0036243107
-
Leptin inhibits stress-induced apoptosis of T lymphocytes
-
Fujita Y, Murakami M, Ogawa Y, et al. Leptin inhibits stress-induced apoptosis of T lymphocytes. Clin Exp Immunol 2002;128:21-26
-
(2002)
Clin Exp Immunol
, vol.128
, pp. 21-26
-
-
Fujita, Y.1
Murakami, M.2
Ogawa, Y.3
-
63
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
Farooqi IS, Matarese G, Lord GM, et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 2002;110:1093-1103
-
(2002)
J Clin Invest
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
-
64
-
-
33847312289
-
A key role of leptin in the control of regulatory T cell proliferation
-
De Rosa V, Procaccini C, Cali G, et al. A key role of leptin in the control of regulatory T cell proliferation. Immunity 2007;26:241-255
-
(2007)
Immunity
, vol.26
, pp. 241-255
-
-
De Rosa, V.1
Procaccini, C.2
Cali, G.3
-
65
-
-
33847288844
-
The leptin connection: Regulatory T cells and autoimmunity
-
Hasenkrug KJ. The leptin connection: Regulatory T cells and autoimmunity. Immunity 2007;26:143-145
-
(2007)
Immunity
, vol.26
, pp. 143-145
-
-
Hasenkrug, K.J.1
-
66
-
-
17044381726
-
Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25+ regulatory T cells
-
Matarese G, Carrieri PB, La Cava A, et al. Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25+ regulatory T cells. Proc Natl Acad Sci USA 2005;102:5150-5155
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5150-5155
-
-
Matarese, G.1
Carrieri, P.B.2
La Cava, A.3
-
67
-
-
16244379546
-
Regulatory T cells and intestinal homeostasis
-
Coombes JL, Robinson NJ, Maloy KJ, et al. Regulatory T cells and intestinal homeostasis. Immunol Rev 2005;204:184-194
-
(2005)
Immunol Rev
, vol.204
, pp. 184-194
-
-
Coombes, J.L.1
Robinson, N.J.2
Maloy, K.J.3
-
68
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S,MalmstromV, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 2000;192:295-302
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
69
-
-
0037446531
-
Cutting edge: Cure of colitis by CD4+CD25+ regulatory T cells
-
Mottet C, Uhlig HH, Powrie F. Cutting edge: Cure of colitis by CD4+CD25+ regulatory T cells. J Immunol 2003;170:3939-3943
-
(2003)
J Immunol
, vol.170
, pp. 3939-3943
-
-
Mottet, C.1
Uhlig, H.H.2
Powrie, F.3
-
70
-
-
0035873418
-
Requirement for leptin in the induction and progression of autoimmune encephalomyelitis
-
Matarese G, Di Giacomo A, Sanna V, et al. Requirement for leptin in the induction and progression of autoimmune encephalomyelitis. J Immunol 2001;166:5909-5916
-
(2001)
J Immunol
, vol.166
, pp. 5909-5916
-
-
Matarese, G.1
Di Giacomo, A.2
Sanna, V.3
-
71
-
-
77951433369
-
Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis
-
Klingenberg R, Lebens M, Hermansson A, et al. Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis. Arterioscler Thromb Vasc Biol 2010;30:946-952
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 946-952
-
-
Klingenberg, R.1
Lebens, M.2
Hermansson, A.3
-
72
-
-
3242657477
-
Leptin: Linking adipocytemetabolismwith cardiovascular and autoimmune diseases
-
Peelman F,Waelput W, Iserentant H, et al. Leptin: Linking adipocytemetabolismwith cardiovascular and autoimmune diseases. Prog Lip Res 2004;43:283-301
-
(2004)
Prog Lip Res
, vol.43
, pp. 283-301
-
-
Peelman, F.1
Waelput, W.2
Iserentant, H.3
-
73
-
-
2342439732
-
Leptin signaling in the central nervous system and the periphery
-
Bjorbaek C, Kahn BB. Leptin signaling in the central nervous system and the periphery. Rec Prog HormRes 2004;59:305-331
-
(2004)
Rec Prog HormRes
, vol.59
, pp. 305-331
-
-
Bjorbaek, C.1
Kahn, B.B.2
-
74
-
-
33750043782
-
Development of leptin antagonists and their potential use in experimental biology and medicine
-
Gertler A. Development of leptin antagonists and their potential use in experimental biology and medicine. Tren EndocrinolMetab 2006;17:372-378
-
(2006)
Tren EndocrinolMetab
, vol.17
, pp. 372-378
-
-
Gertler, A.1
-
75
-
-
0033304576
-
Humanleptindeficiency causedby amissensemutation:multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects.[see comment][erratum appears in j clin endocrinol metab 2000
-
Jan;85(1):416].
-
OzataM,Ozdemir IC, Licinio J.Humanleptindeficiency causedby amissensemutation:multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects.[see comment][erratum appears in J Clin Endocrinol Metab 2000 Jan;85(1):416]. J Clin EndocrinolMetab 1999;84:3686-3695
-
(1999)
J Clin EndocrinolMetab
, vol.84
, pp. 3686-3695
-
-
Ozata, M.1
Ozdemir, I.C.2
Licinio, J.3
-
76
-
-
0037371715
-
Leptin mediates Clostridium difficile toxin A-induced enteritis in mice
-
Mykoniatis A, Anton PM,WlkM, et al. Leptin mediates Clostridium difficile toxin A-induced enteritis in mice. Gastroenterology 2003;124:683-691
-
(2003)
Gastroenterology
, vol.124
, pp. 683-691
-
-
Mykoniatis, A.1
Anton, P.M.2
Wlk, M.3
-
77
-
-
80051551943
-
Toward understanding the role of leptin and leptin receptor antagonism in preclinical models of rheumatoid arthritis
-
Otvos L, Jr., Shao WH, Vanniasinghe AS, et al. Toward understanding the role of leptin and leptin receptor antagonism in preclinical models of rheumatoid arthritis. Peptides 2011;32: 1567-1574
-
(2011)
Peptides
, vol.32
, pp. 1567-1574
-
-
Otvos Jr., L.1
Shao, W.H.2
Vanniasinghe, A.S.3
-
78
-
-
0034998907
-
Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males
-
Matarese G, Sanna V, Di Giacomo A, et al. Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males. Euro J Immunol 2001;31:1324-1332
-
(2001)
Euro J Immunol
, vol.31
, pp. 1324-1332
-
-
Matarese, G.1
Sanna, V.2
Di Giacomo, A.3
-
80
-
-
80055092164
-
Polymorphisms in genes encoding leptin ghrelin and their receptors in germanmultiple sclerosis patients
-
Rey LK, Wieczorek S, Akkad DA, et al. Polymorphisms in genes encoding leptin, ghrelin and their receptors in Germanmultiple sclerosis patients.Mol Cell Probes 2011;25:255-259
-
(2011)
Mol Cell Probes
, vol.25
, pp. 255-259
-
-
Rey, L.K.1
Wieczorek, S.2
Akkad, D.A.3
-
81
-
-
0036312494
-
Leptin accelerates autoimmune diabetes in femaleNODmice
-
Matarese G, Sanna V, Lechler RI, et al. Leptin accelerates autoimmune diabetes in femaleNODmice. Diabetes 2002;51:1356-1361
-
(2002)
Diabetes
, vol.51
, pp. 1356-1361
-
-
Matarese, G.1
Sanna, V.2
Lechler, R.I.3
-
82
-
-
79951502581
-
Restricted leptin antagonism as a therapeutic approach to treatment of autoimmune diseases
-
Babaei A, Zarkesh-Esfahani SH, Bahrami E, Ross RJ. Restricted leptin antagonism as a therapeutic approach to treatment of autoimmune diseases. Hormones (Athens) 2011;10:16-26
-
(2011)
Hormones (Athens
, vol.10
, pp. 16-26
-
-
Babaei, A.1
Zarkesh-Esfahani, S.H.2
Bahrami, E.3
Ross, R.J.4
-
83
-
-
84877157102
-
Leptin receptor antagonist treatment ameliorates the effects of long-term maternal hypoxia on adrenal expression of key steroidogenic genes in the ovine fetus
-
Ducsay CA, Furuta K, Vargas VE, et al. Leptin receptor antagonist treatment ameliorates the effects of long-term maternal hypoxia on adrenal expression of key steroidogenic genes in the ovine fetus. Am J Physiol Regul Integr Comp Physiol 2013;304:R435-R442
-
(2013)
Am J Physiol Regul Integr Comp Physiol
, vol.304
-
-
Ducsay, C.A.1
Furuta, K.2
Vargas, V.E.3
-
84
-
-
0034115688
-
Probiotics in infective diarrhoea and inflammatory bowel diseases ultrasonographic findings in Crohn's disease [letter; Comment
-
Gionchetti P, Rizzello F, Venturi A, et al. Probiotics in infective diarrhoea and inflammatory bowel diseases ultrasonographic findings in Crohn's disease. [letter; comment.]. J Gastroenterol Hepatolo 2000;15:489-493
-
(2000)
J Gastroenterol Hepatolo
, vol.15
, pp. 489-493
-
-
Gionchetti, P.1
Rizzello, F.2
Venturi, A.3
-
85
-
-
0041845066
-
Inhibition of IFN-gamma-inducible protein-10 abrogates colitis in IL-10 (/) mice
-
Singh UP, Singh S, Taub DD, Lillard JW, Jr. Inhibition of IFN-gamma-inducible protein-10 abrogates colitis in IL-10 (/) mice. J Immunol 2003;171:1401-1406
-
(2003)
J Immunol
, vol.171
, pp. 1401-1406
-
-
Singh, U.P.1
Singh, S.2
Taub, D.D.3
Lillard Jr., J.W.4
-
86
-
-
33646107384
-
Large-scale preparation of biologically active mouse and rat leptins and their L39A/D40A/F41Amuteinswhich act as potent antagonists
-
Salomon G, Niv-Spector L, Gussakovsky EE, Gertler A. Large-scale preparation of biologically active mouse and rat leptins and their L39A/D40A/F41Amuteinswhich act as potent antagonists. Prote Exp Purifica 2006;47:128-136
-
(2006)
Prote Exp Purifica
, vol.47
, pp. 128-136
-
-
Salomon, G.1
Niv-Spector, L.2
Gussakovsky, E.E.3
Gertler, A.4
-
87
-
-
33746093293
-
An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1
-
Rajapurohitam V, Javadov S, Purdham DM, et al. An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1. J Mol Cell Cardiol 2006;41:265-274
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 265-274
-
-
Rajapurohitam, V.1
Javadov, S.2
Purdham, D.M.3
-
88
-
-
33846446839
-
Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent
-
Zhang J, Matheny KM, Tumer N, et al. Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent. Am J Physiol Regul Integr Comp Physiol 2007;292(2):R868-R874
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.292
, Issue.2
-
-
Zhang, J.1
Matheny, K.M.2
Tumer, N.3
-
89
-
-
12744273119
-
Luminal leptin induces rapid inhibition of active intestinal absorption of glucosemediated by sodium-glucose cotransporter 1
-
Ducroc R, Guilmeau S, Akasbi K, et al. Luminal leptin induces rapid inhibition of active intestinal absorption of glucosemediated by sodium-glucose cotransporter 1. Diabetes 2005;54:348-354
-
(2005)
Diabetes
, vol.54
, pp. 348-354
-
-
Ducroc, R.1
Guilmeau, S.2
Akasbi, K.3
-
90
-
-
33751504916
-
Prolactin affects leptin action in the bovine mammary gland via themammary fat pad
-
Feuermann Y, Mabjeesh SJ, Niv-Spector L, et al. Prolactin affects leptin action in the bovine mammary gland via themammary fat pad. J Endocrinol 2006;191:407-413
-
(2006)
J Endocrinol
, vol.191
, pp. 407-413
-
-
Feuermann, Y.1
Mabjeesh, S.J.2
Niv-Spector, L.3
-
91
-
-
84893121244
-
Pegylated leptin antagonist ameliorates colitis by inducing regulatoryT cells (Tregs) partially mediated byTGF-beta induction
-
162.4-4 (Abstract
-
Singh UP, Singh N, Singh B, et al. Pegylated leptin antagonist ameliorates colitis by inducing regulatoryT cells (Tregs) partially mediated byTGF-beta induction. J Immunol 2011;186:162.4-4 (Abstract
-
(2011)
J Immunol
, vol.186
-
-
Singh, U.P.1
Singh, N.2
Singh, B.3
-
92
-
-
84885912790
-
Leptin antagonist ameliorates chronic colitis in il-10 mice
-
S0171-2985 doi: 10.1016/j.imbio.2013.04.020. [Epub ahead of print]
-
Singh UP, Singh NP, Guan H, et al. Leptin antagonist ameliorates chronic colitis in IL-10/ mice. Immunobiology 2013; S0171-2985 (13) 00095-8. doi: 10.1016/j.imbio.2013.04.020. [Epub ahead of print].
-
(2013)
Immunobiology
, vol.13
, pp. 00095-00098
-
-
Singh, U.P.1
Singh, N.P.2
Guan, H.3
|