Leptin increase in multiple sclerosis associates with reduced number of CD4+CD25+ regulatory T cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 14, 2005, Pages 5150-5155

  Matarese, Giuseppe ^a,b   Carrieri, Pietro Biagio ^b   La Cava, Antonio ^c   Perna, Francesco ^b   Sanna, Veronica ^a,b   De Rosa, Veronica ^a,b   Aufiero, Daniela ^a,b   Fontana, Silvia ^a   Zappacosta, Serafino ^b  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autoimmunity; Hormones; Metabolism; Tolerance

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; LEPTIN; LEPTIN RECEPTOR; MYELIN BASIC PROTEIN; NEUTRALIZING ANTIBODY; PEPTIDE; PROTEOLIPID PROTEIN;

ADULT; ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; BLOOD LEVEL; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RELEASE; DISEASE MODEL; FEMALE; HUMAN; IMMUNOLOGICAL TOLERANCE; ITALY; MAJOR CLINICAL STUDY; MALE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; RECEPTOR UPREGULATION; RELAPSE; REMISSION; T LYMPHOCYTE;

ADULT; ANIMALS; CASE-CONTROL STUDIES; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; HUMANS; INTERFERON TYPE II; LEPTIN; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; MIDDLE AGED; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; MYELIN BASIC PROTEINS; NEUTRALIZATION TESTS; RECEPTORS, CELL SURFACE; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTE SUBSETS;

EID: 17044381726     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0408995102     Document Type: Article

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