Leptin levels in the acute stage of ulcerative colitis

Journal of Gastroenterology and Hepatology (Australia)

Volumn 19, Issue 4, 2004, Pages 429-432

  Tuzun, Ahmet ^a   Uygun, Ahmet ^a   Yesilova, Zeki ^a   Ozel, A Melih ^a,b   Erdil, Ahmet ^a   Yaman, Halil ^a   Bagci, Sait ^a   Gulsen, Mustafa ^a   Karaeren, Necmettin ^a   Dagalp, Kemal ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

^b Department of Biochemistry Gülhane Mil Medical Academy ^*  (United States)

Author keywords

Anorexia; Leptin; Ulcerative colitis; Weight loss

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; LEPTIN;

ACUTE DISEASE; ADULT; ALBUMIN BLOOD LEVEL; ANOREXIA; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; ERYTHROCYTE SEDIMENTATION RATE; EVALUATION; HEMOCONCENTRATION; HUMAN; LEUKOCYTE COUNT; MALE; MEASUREMENT; PATIENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; ULCERATIVE COLITIS; WEIGHT REDUCTION;

EID: 2342564361     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2003.03300.x     Document Type: Article

References (20)

1. Zhang Y, Proenca R, Maffei M et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-32.
2. Halaas JL, Gajiwala KS, Maffei M et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 1995; 269: 543-6.
3. Campfield LA, Smith FJ, Guisez Y et al. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 1995; 269: 546-9.
4. Ballinger A. Divergency of leptin response in intestinal inflammation. Gut 1999; 44: 588-9.
5. Tartaglia LA, Dembski M, Weng X et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995; 83: 1263-71.
6. Darnell JE Jr,, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264: 1415-21.
7. Hamann A, Busing B, Kausch C et al. Chronic leptin treatment does not prevent the development of obesity in transgenic mice with brown fat deficiency. Diabetologia 1997; 40: 810-15.
8. Morton NM, Emilsson V, Liu YL et al. Leptin action in intestinal cells. J. Biol. Chem. 1998; 273: 26194-201.
9. Silk DB, Payne-James J. Inflammatory bowel disease: nutritional implications and treatment. Proc. Nutr. Soc. 1989; 48: 355-61.
10. Grunfeld C, Zhao C, Fuller J et al. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. J. Clin. Invest. 1996; 97: 2152-7.
11. Sarraf P, Frederich RC, Turner EM et al. Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J. Exp. Med. 1997; 185: 171-5.
12. Janik JE, Curti BD, Considine RV et al. Interleukin 1 alpha increases serum leptin concentrations in humans. J. Clin. Endocrinol. Metab. 1997; 82: 3084-6.
13. Zumbach MS, Boehme MW, Wahl P. Tumor necrosis factor increases serum leptin levels in humans. J. Clin. Endocrinol. Metab. 1997; 82: 4080-2.
14. Rachmilewitz D. Coated mesalazine (5-aminosalicylic acid) versus sulfasalazine in the treatment of active ulcerative colitis: A randomized trial. BMJ 1989; 298: 82-6.
15. Rigaud D, Angel LA, Cerf M et al. Mechanism of decreased food intake during weight loss in adult Crohn's disease patients without obvious malabsorption. Am. J. Clin. Nutr. 1994; 60: 775-81.
16. Barbier M, Cherbut C, Aube AC et al. Elevated plasma leptin concentrations in early stages of experimental intestinal inflammation in rats. Gut 1998; 43: 783-90.
17. Tateishi H, Mitsuyama K, Toyonaga A, Tomoyose M, Tanikawa K. Role of cytokines in experimental colitis: relation to intestinal permeability. Digestion 1997;58: 271-81.
18. Neilly PJ, Gardiner KR, Kirk SJ et al. Endotoxaemia and cytokine production in experimental colitis. Br. J. Surg. 1995; 82: 1479-82.
19. Inoue S, Matsumoto T, Mizuno M, Kuroki F, Hoshika K, Shimizu M. Characterization of cytokine expression in the rectal mucosa of ulcerative colitis: correlation with disease activity. Am. J. Gastroenterol. 1999; 94: 2441-6.
20. Hoppin AG, Kaplan LM, Zurakowski D, Leichtner AM, Bousvaros A. Serum leptin in children and young adults with inflammatory bowel disease. J. Pediatr. Gastroenterol. Nutr. 1998; 26: 500-5.