메뉴 건너뛰기




Volumn 108, Issue 10, 2001, Pages 1483-1494

PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine

Author keywords

[No Author keywords available]

Indexed keywords

CEFALEXIN; COLCHICINE; DIPEPTIDE; GLYCYLSARCOSINE; LEPTIN; LEPTIN RECEPTOR; PEPTIDE TRANSPORTER 1; UNCLASSIFIED DRUG;

EID: 0035191858     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI13219     Document Type: Article
Times cited : (200)

References (61)
  • 2
    • 0030990091 scopus 로고    scopus 로고
    • The oligopeptide transporter (Pept-1) in human intestine: Biology, and function
    • (1997) Gastroenterology , vol.113 , pp. 332-340
    • Adibi, S.A.1
  • 3
    • 0028920129 scopus 로고
    • Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localizadon
    • (1995) J. Biol. Chem. , vol.270 , pp. 6456-6463
    • Liang, R.1
  • 4
    • 0027967880 scopus 로고
    • Expression cloning of a cDNA from rabbit small intestine related co proton-coupled transport of peptides, beta-lactam antibiotics and ACE-inhibitors
    • (1994) Pflugers Arch. , vol.429 , pp. 146-149
    • Boll, M.1
  • 5
    • 0028333611 scopus 로고
    • Expression cloning of a mammalian proton-coupled oligopeptide transporter
    • (1994) Nature , vol.368 , pp. 563-566
    • Fei, Y.J.1
  • 8
    • 0029977968 scopus 로고    scopus 로고
    • Mechanisms of the human intestinal H+-coupled oligopeptide transporter hPEPT1
    • (1996) J. Biol. Chem. , vol.271 , pp. 5430-5437
    • Mackenzie, B.1
  • 14
    • 0035011324 scopus 로고    scopus 로고
    • Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: Transport of bacterial peptides influences expression of MHC class 1 molecules
    • (2001) Gastroenterology , vol.120 , pp. 1666-1679
    • Merlin, D.1
  • 17
    • 0032933703 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of dietary regulation on rat intestinal H+/Peptide transporter PepT1
    • (1999) Gastroenterology , vol.116 , pp. 354-362
    • Shiraga, T.1
  • 23
    • 0032982247 scopus 로고    scopus 로고
    • Neural modulation of cephalexin intestinal absorption through the di- and tripeptide brush border transporter of rat jejunum in vivo
    • (1999) J. Pharmacol. Exp. Ther. , vol.288 , pp. 1037-1044
    • Berlioz, F.1
  • 26
    • 15144346706 scopus 로고    scopus 로고
    • The predominant contribution of oligopeptide transporter PepT1 to intestinal absorption of beta-lactam antibiotics in the rat small intestine
    • (1997) J. Pharm. Pharmacol. , vol.49 , pp. 796-801
    • Tamai, I.1
  • 27
  • 29
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1
  • 30
    • 2442654859 scopus 로고
    • Identification and expression cloning of a leptin receptor, OB-R
    • (1995) Cell , vol.83 , pp. 1263-1271
    • Tartaglia, L.A.1
  • 31
    • 0029073613 scopus 로고
    • Weight-reducing effects of the plasma protein encoded by the obese gene
    • (1995) Science , vol.269 , pp. 543-546
    • Halaas, J.L.1
  • 32
    • 0030866843 scopus 로고    scopus 로고
    • Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans
    • (1997) Nat. Med. , vol.3 , pp. 1029-1033
    • Masuzaki, H.1
  • 33
    • 0032552112 scopus 로고    scopus 로고
    • The stomach is a source of leptin
    • (1998) Nature , vol.394 , pp. 790-793
    • Bado, A.1
  • 34
    • 0033930048 scopus 로고    scopus 로고
    • Leptin secretion and leptin receptor in the human stomach
    • (2000) Gut , vol.47 , pp. 178-183
    • Sobhani, I.1
  • 36
    • 0022652642 scopus 로고
    • Interaction of peptide YY with rat intestinal epithelial plasma membranes: Binding of the radioiodinated peptide
    • (1986) Endocrinology , vol.118 , pp. 1910-1917
    • Laburthe, M.1
  • 37
    • 0030918156 scopus 로고    scopus 로고
    • Several receptors mediate the antisecretory effect of peptide YY, neuropeptide Y, and pancreatic polypeptide on VIP-induced fluid secretion in the rat jejunum in vivo
    • (1997) Peptides , vol.18 , pp. 551-557
    • Souli, A.1
  • 41
    • 0015160590 scopus 로고
    • Intestinal transport of dipeptides in man: Relative importance of hydrolysis and intact absorption
    • (1971) J. Clin. Invest. , vol.50 , pp. 2266-2275
    • Adibi, S.A.1
  • 43
    • 0015399657 scopus 로고
    • Comparison of intestinal absorption rates of glycine and glycylglycine in man and the effect of glucose in the perfusing fluid
    • (1972) Clin. Sci. , vol.43 , pp. 443-453
    • Cook, G.C.1
  • 44
    • 18744431873 scopus 로고    scopus 로고
    • Structure, function, and molecular modeling approaches to the study of the intestinal dipeptide transporter PepT1
    • (1998) J. Pharm. Sci. , vol.87 , pp. 1286-1291
    • Bolger, M.B.1
  • 51
    • 2442654859 scopus 로고
    • Identification and expression cloning of a leptin receptor, OB-R
    • (1995) Cell , vol.83 , pp. 1263-1271
    • Tartaglia, L.A.1
  • 52
    • 0030039272 scopus 로고    scopus 로고
    • Abnormal splicing of the leptin receptor in diabetic mice
    • (1996) Nature , vol.379 , pp. 632-635
    • Lee, G.H.1
  • 53
    • 0032429019 scopus 로고    scopus 로고
    • Differential signaling and regulation of apical vs. basolateral EGFR in polarized epithelial cells
    • (1998) Am. J. Physiol. , vol.275
    • Kuwada, S.K.1
  • 57
    • 0033542752 scopus 로고    scopus 로고
    • A src-related kinase in the brush border membranes of gastrointestinal cells is regulated by c-met
    • (1999) Exp. Cell Res. , vol.250 , pp. 86-98
    • Sunitha, I.1
  • 58
    • 0029739826 scopus 로고    scopus 로고
    • Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
    • (1996) Nat. Genet. , vol.14 , pp. 95-97
    • Vaisse, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.