SCOPUS 정보 검색 플랫폼

Volumn 8, Issue 5, 2002, Pages 500-508

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

(18) Lock, Christopher a Hermans, Guy a Pedotti, Rosetta a Brendolan, Andrea b Schadt, Eric c Garren, Hideki a Langer Gould, Annette a Strober, Samuel b Cannella, Barbara f Allard, John g Klonowski, Paul g Austin, Angela g Lad, Nagin g Kaminski, Naftali d,e Galli, Stephen J b Raine, Cedric S f Heller, Renu g Steinman, Lawrence a

a STANFORD UNIVERSITY (United States)

b STANFORD UNIVERSITY SCHOOL OF MEDICINE (United States)

c ROSETTA INPHARMATICS (United States)

d Rosetta Inpharmatics ^* (United States)

e UNIVERSITY OF CALIFORNIA (United States)

f ALBERT EINSTEIN COLLEGE OF MEDICINE (United States)

g ROCHE BIOSCIENCE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FC RECEPTOR; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 17; INTERLEUKIN 6; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CASE REPORT; CHRONICITY; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFLAMMATION; KNOCKOUT GENE; MALE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; TREATMENT OUTCOME; UNINDEXED SEQUENCE; VALIDATION PROCESS;

ACUTE DISEASE; ANIMALS; AUTOPSY; CHRONIC DISEASE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; INFLAMMATION; INTERFERON TYPE II; INTERLEUKIN-17; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MULTIPLE SCLEROSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, FC; REPRODUCIBILITY OF RESULTS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0036105484 PISSN: 10788956 EISSN: None Source Type: Journal
DOI: 10.1038/nm0502-500 Document Type: Article

Times cited : (1475)

References (43)

1
- 0002086377
- The neuropathology of multiple sclerosis
- (eds. Raine, C.S., McFarland, H.F. & Tourtelotte, W.W) (Chapman and Hall, London)
- Multiple Sclerosis: Clinical and Pathogenetic Basis
- (1997) Multiple Sclerosis: Clinical and Pathogenetic Basis , pp. 151-171
- Raine, C.S.¹

2
- 0032441150
- Cluster analysis and display of genome-wide expression patterns
- Proc. Natl. Acad. Sci. USA
- (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14863-14868
- Eisen, M.B.¹ Spellman, P.T.² Brown, P.O.³ Botstein, D.⁴

3
- 17944366528
- Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles
- Toxicol. Appl. Pharmacol.
- (2001) Toxicol. Appl. Pharmacol. , vol.175 , pp. 28-42
- Waring, J.F.¹

4
- 0034536614
- Analyzing high-density oligonucleotide gene expression array data
- J. Cell Biochem.
- (2000) J. Cell Biochem. , vol.80 , pp. 192-202
- Schadt, E.E.¹ Li, C.² Su, C.³ Wong, W.H.⁴

5
- 0035752668
- Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data
- J. Cell Biochem.
- (2001) J. Cell Biochem. , pp. 120-125
- Schadt, E.E.¹ Li, C.² Ellis, B.³ Wong, W.H.⁴

6
- 0027253487
- Isolation and characterization of a novel B cell activation gene
- J. Immunol.
- (1993) J. Immunol. , vol.150 , pp. 3895-3904
- Hong, J.X.¹ Wilson, G.L.² Fox, C.H.³ Kehrl, J.H.⁴

7
- 0026768703
- Molecular cloning of human macrophage capping protein cDNA. A unique member of the gelsolin/villin family expressed primarily in macrophages
- J. Biol. Chem.
- (1992) J. Biol. Chem. , vol.267 , pp. 16545-16552
- Dabiri, G.A.¹ Young, C.L.² Rosenbloom, J.³ Southwick, F.S.⁴

8
- 0027480450
- MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL 2
- Proc. Natl. Acad. Sci. USA
- (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3516-3520
- Kozopas, K.M.¹ Yang, T.² Buchan, H.L.³ Zhou, P.⁴ Craig, R.W.⁵

9
- 0031571093
- Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation
- Genomics
- (1997) Genomics , vol.43 , pp. 221-225
- Rehli, M.¹ Krause, S.W.² Andreesen, R.³

10
- 0032736185
- Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis
- J. Immunol.
- (1999) J. Immunol. , vol.163 , pp. 6551-6556
- Davoust, N.¹

11
- 0026447990
- The CD59 antigen - A multifunctional molecule
- Tissue Antigens
- (1992) Tissue Antigens , vol.40 , pp. 213-220
- Walsh, L.A.¹ Tone, M.² Thiru, S.³ Waldmann, H.⁴

12
- 0025107677
- Cytokine accumulations in CSF of multiple sclerosis patients: Frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6
- Neurology
- (1990) Neurology , vol.40 , pp. 1735-1739
- Hauser, S.L.¹ Doolittle, T.H.² Lincoln, R.³ Brown, R.H.⁴ Dinarello, C.A.⁵

13
- 0025856061
- Experimental autoimmune encephalomyelitis is exacerbated by IL-1 α and suppressed by soluble IL-1 receptor
- J. Immunol.
- (1991) J. Immunol. , vol.146 , pp. 2983-2989
- Jacobs, C.A.¹

14
- 0344389016
- Interleukin- 17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
- Mult. Scler.
- (1999) Mult. Scler. , vol.5 , pp. 101-104
- Matusevicius, D.¹

15
- 0031671153
- Multiple sclerosis: Expression of molecules of the tumor necrosis factor ligand and receptor families in relationship to the demyelinated plaque
- Rev. Neurol. (Paris)
- (1998) Rev. Neurol. (Paris) , vol.154 , pp. 577-585
- Raine, C.S.¹ Bonetti, B.² Cannella, B.³

16
- 0026611673
- IL-6 and NF-IL6 in acute-phase response and viral infection
- Immunol. Rev.
- (1992) Immunol. Rev. , vol.127 , pp. 25-50
- Akira, S.¹ Kishimoto, T.²

17
- 0029411144
- Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL- 6 bioactivity in central nervous system and circulation
- Mol. Med.
- (1995) Mol. Med. , vol.1 , pp. 795-805
- Gijbels, K.¹ Brocke, S.² Abrams, J.S.³ Steinman, L.⁴

18
- 0030639621
- Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice
- J. Immunol.
- (1997) J. Immunol. , vol.158 , pp. 438-445
- Akassoglou, K.¹ Probert, L.² Kontogeorgos, G.³ Kollias, G.⁴

19
- 0033595764
- Neuronal activitydependent cell survival mediated by transcription factor MEF 2
- Science
- (1999) Science , vol.286 , pp. 785-790
- Mao, Z.¹ Bonni, A.² Xia, F.³ Nadal-Vicens, M.⁴ Greenberg, M.E.⁵

20
- 0035479008
- Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis
- J. Neuroimmunol.
- (2001) J. Neuroimmunol. , vol.119 , pp. 248-260
- Penkowa, M.¹

21
- 0033958462
- Glutamate excitotoxicity in a model of multiple sclerosis
- Nature Med.
- (2000) Nature Med. , vol.6 , pp. 67-70
- Pitt, D.¹ Werner, P.² Raine, C.S.³

22
- 0032576752
- Axonal transection in the lesions of multiple sclerosis
- N. Engl. J. Med.
- (1998) N. Engl. J. Med. , vol.338 , pp. 278-285
- Trapp, B.D.¹

23
- 0027443880
- Molecular cloning of M6: Identification of a PLP/DM 20 gene family
- Neuron
- (1993) Neuron , vol.11 , pp. 423-431
- Yan, Y.¹ Lagenaur, C.² Narayanan, V.³

24
- 0026506799
- Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β 1 integrin
- Nature
- (1992) Nature , vol.356 , pp. 63-66
- Yednock, T.A.¹

25
- 0033231305
- Assessment of the utility of animal models for MS and demyelinating disease in the design of rational therapy
- Neuron
- (1999) Neuron , vol.24 , pp. 511-514
- Steinman, L.¹

26
- 0028042424
- FcRγ chain deletion results in pleiotrophic effector cell defects
- Cell
- (1994) Cell , vol.76 , pp. 519-529
- Takai, T.¹ Li, M.² Sylvestre, D.³ Clynes, R.⁴ Ravetch, J.V.⁵

27
- 0030897232
- Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and FcγRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis
- J. Clin. Invest.
- (1997) J. Clin. Invest. , vol.99 , pp. 901-914
- Miyajima, I.¹

28
- 0035910392
- Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor
- Science
- (2001) Science , vol.291 , pp. 484-486
- Samuelsson, A.¹ Towers, T.L.² Ravetch, J.V.³

29
- 0028293458
- Intravenous immunoglobulin treatment of experimental T cellmediated autoimmune disease. Upregulation of T-cell proliferation and downregulation of tumor necrosis factor α secretion
- J. Clin. Invest.
- (1994) J. Clin. Invest. , vol.93 , pp. 600-605
- Achiron, A.¹

30
- 0030961031
- Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2-restricted T-cell clones from multiple sclerosis patients. Identity of key contact residues in the B-cell and T-cell epitopes
- J. Clin. Invest.
- (1997) J. Clin. Invest. , vol.100 , pp. 1114-1122
- Wucherpfennig, K.W.¹

31
- 0028864784
- Fine specificity of the antibody response to myelin basic protein in the central nervous system in multiple sclerosis: The minimal B-cell epitope and a model of its features
- Proc. Natl. Acad. Sci. USA
- (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11061-11065
- Warren, K.G.¹ Catz, I.² Steinman, L.³

32
- 0032950794
- Identification of autoantibodies associated with myelin damage in multiple sclerosis
- Nature Med.
- (1999) Nature Med. , vol.5 , pp. 170-175
- Genain, C.P.¹ Cannella, B.² Hauser, S.L.³ Raine, C.S.⁴

33
- 0032882174
- Analysis of gene expression in mutiple sclerosis lesions using cDNA microarrays
- Ann. Neural.
- (1999) Ann. Neural. , vol.46 , pp. 425-428
- Whitney, L.W.¹

34
- 0024325672
- Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy
- Cell
- (1989) Cell , vol.59 , pp. 247-255
- Wraith, D.C.¹ Smilek, D.E.² Mitchell, D.J.³ Steinman, L.⁴ McDevitt, H.O.⁵

35
- 0035286208
- An unexpected version of horror autotoxicus: Anaphylactic shock to a self-peptide
- Nature Immunol.
- (2001) Nature Immunol. , vol.2 , pp. 216-222
- Pedotti, R.¹

36
- 0342906187
- Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
- Ann. Neurol.
- (2000) Ann. Neurol. , vol.47 , pp. 707-717
- Lucchinetti, C.¹

37
- 0009573338
- A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex
- The Multiple Sclerosis Genetics Group
- Nature Genet.
- (1996) Nature Genet. , vol.13 , pp. 469-471
- Haines, J.L.¹

38
- 15844366743
- A full genome search in multiple sclerosis
- Nature Genet.
- (1996) Nature Genet. , vol.13 , pp. 472-476
- Ebers, G.C.¹

39
- 15844368830
- A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22
- Nature Genet.
- (1996) Nature Genet. , vol.13 , pp. 464-468
- Sawcer, S.¹

40
- 0037083294
- G-CSF therapy of ongoing experimental allergic encephalomyelitis via chemokine- and cytokine-based immune deviation
- J. Immunol.
- (2002) J. Immunol. , vol.168 , pp. 2011-2019
- Zavala, F.¹

41
- 0035873418
- Requirement for leptin in the induction and progression of autoimmune encephalomyelitis
- J. Immunol.
- (2001) J. Immunol. , vol.166 , pp. 5909-5916
- Matarese, G.¹

42
- 0026800892
- The cloning of a family of genes that encode the melanocortin receptors
- Science
- (1992) Science , vol.257 , pp. 1248-1251
- Mountjoy, K.G.¹ Robbins, L.S.² Mortrud, M.T.³ Cone, R.D.⁴

43
- 0031570394
- Stress and autoimmunity: The neuropeptides corticotropin-releasing factor and urocortin suppress encephalomyelitis via effects on both the hypothalamic-pituitary-adrenal axis and the immune system
- J. Immunol.
- (1997) J. Immunol. , vol.158 , pp. 5751-5756
- Poliak, S.¹

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