Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes - Indication of an increased environmental pressure?

Diabetologia

Volumn 46, Issue 3, 2003, Pages 420-425

  Hermann, R ^a   Knip, M ^c   Veijola, R ^b   Simell, O ^a   Laine, A P ^d   Akerblom H K ^c   Groop, P H ^c   Forsblom, C ^c   Pettersson Fernholm, K ^c   Ilonen, J ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF OULU   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d NONE

Author keywords

Complex disease; CTLA4; Environmental factors; Genetic susceptibility; HLA DQ; HLA DR; IDDM12; IDDM2; Temporal variation; Type 1 diabetes mellitus

Indexed keywords

HLA DQ ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; CHI SQUARE TEST; CHILD; DISEASE COURSE; ENVIRONMENTAL FACTOR; FEMALE; FINLAND; FISHER EXACT TEST; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0038222568     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-003-1045-4     Document Type: Article

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