Absence of leptin triggers type 1 diabetes

Nature Medicine

Volumn 20, Issue 7, 2014, Pages 705-706

  Mittendorfer, Bettina ^a   Klein, Samuel ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; GLUCOSE; GLYCEROL; INSULIN; LEPTIN;

ADIPOSE TISSUE; CORTICOTROPIN RELEASE; FATTY ACID BLOOD LEVEL; GLUCAGON BLOOD LEVEL; GLUCAGON RELEASE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLYCOGEN LIVER LEVEL; GLYCOGENOLYSIS; HUMAN; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN DEFICIENCY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULIN TREATMENT; KETOACIDOSIS; KETOGENESIS; LEPTIN DEFICIENCY; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LEPTIN; PITUITARY-ADRENAL SYSTEM;

EID: 84903935556     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3629     Document Type: Review

References (10)

1. Unger, R.H. & Cherrington, A.D. J. Clin. Invest. 122, 4-12 (2012).
2. Dabelea, D. et al. Diabetes 52, 2833-2839 (2003).
3. Purnell, J.Q., Zinman, B. & Brunzell, J.D. Circulation 127, 180-187 (2013).
4. Van Belle, T.L., Taylor, P. & von Herrath, M.G. Drug Discov. Today Dis. Models 6, 41-45 (2009).
5. Mac Gillivray, M.H. et al. Diabetes Care 5 Suppl 1, 38-47 (1982).
6. Kiess, W. et al. Eur. J. Endocrinol. 138, 501-509 (1998).
7. Perry, R.J. et al. Nat. Med. 20, 759-763 (2014).
8. Lee, Y., Wang, M.Y., Du, X.Q., Charron, M.J. & Unger, R.H. Diabetes 60, 391-397 (2011).
9. Lee, Y. et al. Proc. Natl. Acad. Sci. USA 109, 14972-14976 (2012).
10. Hanaki, K., Becker, D.J. & Arslanian, S.A. J. Clin. Endocrinol. Metab. 84, 1524-1526 (1999).