The role of DNA exonucleases in protecting genome stability and their impact on ageing

Age

Volumn 34, Issue 6, 2012, Pages 1317-1340

  Mason, Penelope A ^a   Cox, Lynne S ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Ageing; Aging; DNA repair; DNA replication; EXDL2; EXOG; Exonuclease; FAN1; FEN1; Mitochondria; Proofreading; WRN

Indexed keywords

DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA DIRECTED DNA POLYMERASE GAMMA; DNA EXONUCLEASE; DNA POLYMERASE; DOUBLE STRANDED DNA; ENDONUCLEASE G; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 5; EXONUCLEASE; FANCONI ANEMIA PROTEIN; FLAP ENDONUCLEASE; MRE11 PROTEIN; PROTEIN P53; PROTEIN RAD9; THREE PRIME REPAIR EXONUCLEASE 1; THREE PRIME REPAIR EXONUCLEASE 2; UNCLASSIFIED DRUG; WERNER SYNDROME PROTEIN; APEX1 PROTEIN, HUMAN; APEX2 PROTEIN, HUMAN; DNA DIRECTED DNA POLYMERASE; DNA2 PROTEIN, HUMAN; EXODEOXYRIBONUCLEASE; FEN1 PROTEIN, HUMAN; HELICASE; PHOSPHOPROTEIN; POLG PROTEIN, HUMAN; RECQ HELICASE; TREX2 PROTEIN, HUMAN; WRN PROTEIN, HUMAN;

AGING; AICARDI GOUTIERES SYNDROME; ARTICLE; ATAXIA TELANGIECTASIA; AUTOIMMUNE DISEASE; CELL METABOLISM; COCKAYNE SYNDROME; DISEASE PREDISPOSITION; DNA CLEAVAGE; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; DNA STRUCTURE; ENCEPHALITIS; ENZYME ACTIVITY; EXCISION REPAIR; FANCONI ANEMIA; GENE LOSS; GENE MUTATION; GENETIC STABILITY; HUMAN; IMMUNE DEFICIENCY; MALIGNANT NEOPLASTIC DISEASE; MISMATCH REPAIR; MITOCHONDRIAL GENOME; NIJMEGEN BREAKAGE SYNDROME; NONHUMAN; POLYMERIZATION; PREMATURE AGING; TRICHOTHIODYSTROPHY; TRINUCLEOTIDE REPEAT; WERNER SYNDROME; XERODERMA PIGMENTOSUM; ANIMAL; GENETICS; GENOMIC INSTABILITY; PHYSIOLOGY; REVIEW; TELOMERE HOMEOSTASIS;

AGING; ANIMALS; DNA DAMAGE; DNA HELICASES; DNA MISMATCH REPAIR; DNA REPAIR; DNA REPLICATION; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASES; FLAP ENDONUCLEASES; GENOMIC INSTABILITY; HUMANS; PHOSPHOPROTEINS; RECQ HELICASES; TELOMERE HOMEOSTASIS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84876459277     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-011-9306-5     Document Type: Article

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