Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeres

Genes and Development

Volumn 21, Issue 17, 2007, Pages 2234-2247

  Siegl Cachedenier, Irene ^a   Muñoz, Purificación ^a   Flores, Juana M ^b   Klatt, Peter ^a   Blasco, María A ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Aging; Cancer; MMR; PMS2; Telomerase knockout mice; Telomeres

Indexed keywords

MISMATCH REPAIR PROTEIN PMS2; PROTEIN P21;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL IMMORTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; TELOMERE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; DNA MISMATCH REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; LIFE EXPECTANCY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSATELLITE INSTABILITY; NEOPLASMS, EXPERIMENTAL; PROTO-ONCOGENE PROTEINS P21(RAS); RECOMBINATION, GENETIC; TELOMERASE; TELOMERE;

MAMMALIA; MUS;

EID: 34447533257     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.430107     Document Type: Article

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