DNA replication: Partners in the Okazaki two-step

Current Biology

Volumn 11, Issue 20, 2001, Pages

  MacNeill, Stuart A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA;

EID: 0035899864     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00500-0     Document Type: Review

References (14)

1. The DNA replication fork in eukaryotic cells
2. Characterization of the enzymatic properties of the yeast Dna2 helicase/endonuclease suggests a new model for Okazaki fragment processing
3. RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes
4. Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease
5. The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast
6. A yeast gene required for DNA replication encodes a protein with homology to DNA helicases
7. DNA2 encodes a DNA helicase essential for replication of eukaryotic chromosomes
8. A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function
9. Characterisation of Saccharomyces cerevisiae dna2 mutants suggests a role for the helicase late in S-phase
10. Dna2 of Saccharomyces cerevisiae possesses a single-stranded DNA-specific endonuclease activity that is able to act on double-stranded DNA in the presence of ATP
11. Dna2 mutants reveal interactions with DNA polymerase α and Ctf4, a Pol α accessory factor, and show that full Dna2 helicase activity is not essential for growth
12. Conserved domains in DNA repair proteins and evolution of repair systems
13. The nuclease activity of the yeast Dna2 protein, which is related to the RecB-like nucleases, is essential in vivo
14. The endonuclease activity of the yeast Dna2 enzyme is essential in vivo