ATM-dependent Phosphorylation of Human Rad9 is Required for Ionizing Radiation-induced Checkpoint Activation

Journal of Biological Chemistry

Volumn 276, Issue 19, 2001, Pages 16580-16586

  Chen, Ming Jiu ^a   Lin, Yi Tzu ^a   Lieberman, Howard B ^b   Chen, Gang ^a,c   Lee, Eva Y H P ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; IONIZING RADIATION; PROTEINS; ULTRAVIOLET RADIATION;

HYPERPHOSPHORYLATION;

BIOCHEMISTRY;

ATM PROTEIN; DNA; HYDROXYUREA; PROTEIN RAD9; PROTEIN SERINE THREONINE KINASE; RAD51 PROTEIN; SERINE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; HYBRID PROTEIN; PHOSPHOSERINE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; DNA DAMAGE; DNA REPAIR; FIBROBLAST; HUMAN; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; SCHIZOSACCHAROMYCES POMBE; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION; ATAXIA TELANGIECTASIA; GENETICS; LUNG; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RADIATION EXPOSURE; SCHIZOSACCHAROMYCES;

ANIMALIA; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE; ATAXIA;

ATAXIA TELANGIECTASIA; CELL CYCLE; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; HUMANS; HYDROXYUREA; LUNG; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING; RECOMBINANT FUSION PROTEINS; SCHIZOSACCHAROMYCES; TUMOR SUPPRESSOR PROTEINS; ULTRAVIOLET RAYS;

EID: 0035844130     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008871200     Document Type: Article

References (75)

1. Dasika, G. K., Lin, S. C., Zhao, S., Sung, P., Tomkinson, A., and Lee, E. Y. (1999) Oncogene 18, 7883-7899
2. Elledge, S. J. (1996) Science 274, 1664-1672
3. Wang, J. Y. (1998) Curr. Opin. Cell Biol. 10, 240-247
4. Weinert, T. (1998) Cell 94, 555-558
5. Hartwell, L., Weinert, T., Kadyk, L., and Garvik, B. (1994) Cold Spring Harbor Symp. Quant. Biol. 59, 259-263
6. Lengauer, C., Kinzler, K. W., and Vogelstein, B. (1998) Nature 396, 643-649
7. Venclovas, C., and Thelen, M. P. (2000) Nucleic Acids Res. 28, 2481-2493
8. O'Connell, M. J., Walworth, N. C., and Carr, A. M. (2000) Trends Cell Biol. 10, 296-303
9. Bentley, N. J., and Carr, A. M. (1997) Biol. Chem. 378, 1267-1274
10. Stewart, E., and Enoch, T. (1996) Curr. Opin. Cell Biol. 8, 781-787
11. Rhind, N., and Russell, P. (1998) Curr. Opin. Cell Biol. 10, 749-758
12. Caspari, T., and Carr, A. M. (1999) Biochimie (Paris) 81, 173-181
13. al-Khodairy, F., and Carr, A. M. (1992) EMBO J. 11, 1343-1350
14. al-Khodairy, F., Fotou, E., Sheldrick, K. S., Griffiths, D. J., Lehmann, A. R., and Carr, A. M. (1994) Mol. Biol. Cell 5, 147-160
15. Long, K. E., Sunnerhagen, P., and Subramani, S. (1994) Gene (Amst.) 148, 155-159
16. Caspari, T., Dahlen, M., Kanter-Smoler, G., Lindsay, H. D., Hofmann, K., Papadimitriou, K., Sunnerhagen, P., and Carr, A. M. (2000) Mol. Cell. Biol. 20, 1254-1262
17. Carr, A. M. (1998) Microbiology 144, 5-11
18. Edwards, R. J., Bentley, N. J., and Carr, A. M. (1999) Nat. Cell Biol. 1, 393-398
19. Lindsay, H. D., Griffiths, D. J., Edwards, R. J., Christensen, P. U., Murray, J. M., Osman, F., Walworth, N., and Carr, A. M. (1998) Genes Dev. 12, 382-395
20. Walworth, N. C., and Bernards, R. (1996) Science 271, 353-356
21. Bentley, N. J., Holtzman, D. A., Flaggs, G., Keegan, K. S., DeMaggio, A., Ford, J. C., Hoekstra, M., and Carr, A. M. (1996) EMBO J. 15, 6641-6651
22. Bluyssen, H. A., van Os, R. I., Naus, N. C., Jaspers, I., Hoeijmakers, J. H., and de Klein, A. (1998) Genomics 54, 331-337
23. Freire, R., Murguia, J. R., Tarsounas, M., Lowndes, N. F., Moens, P. B., and Jackson, S. P. (1998) Genes Dev. 12, 2560-2573
24. Lieberman, H. B., Hopkins, K. M., Nass, M., Demetrick, D., and Davey, S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 13890-13895
25. Marathi, U. K., Dahlen, M., Sunnerhagen, P., Romero, A. V., Ramagli, L. S., Siciliano, M. J., Li, L., and Legerski, R. J. (1998) Genomics 54, 344-347
26. Parker, A. E., Van de Weyer, I., Laus, M. C., Verhasselt, P., and Luyten, W. H. (1998) J. Biol. Chem. 273, 18340-18346
27. Udell, C. M., Lee, S. K., and Davey, S. (1998) Nucleic Acids Res. 26, 3971-3976
28. Li, L., Peterson, C. A., Kanter-Smoler, G., Wei, Y. F., Ramagli, L. S., Sunnerhagen, P., Siciliano, M. J., and Legerski, R. J. (1999) Oncogene 18, 1689-1699
29. Hang, H., and Lieberman, H. B. (2000) Genomics 65, 24-33
30. St. Onge, R. P., Udell, C. M., Casselman, R., and Davey, S. (1999) Mol. Biol. Cell 10, 1985-1995
31. Volkmer, E., and Karnitz, L. M. (1999) J. Biol. Chem. 274, 567-570
32. Parker, A. E., Van de Weyer, I., Laus, M. C., Oostveen, I., Yon, J., Verhasselt, P., and Luyten, W. H. (1998) J. Biol. Chem. 273, 18332-18339
33. Bessho, T., and Sancar, A. (2000) J. Biol. Chem. 275, 7451-7454
34. Burtelow, M. A., Kaufmann, S. H., and Karnitz, L. M. (2000) J. Biol. Chem. 275, 26343-26348
35. Ahmed, S., and Hodgkin, J. (2000) Nature 403, 159-164
36. Weiss, R. S., Enoch, T., and Leder, P. (2000) Genes Dev. 14, 1886-1898
37. Gartner, A., Milstein, S., Ahmed, S., Hodgkin, J., and Hengartner, M. O. (2000) Mol. Cell 5, 435-443
38. Savitsky, K., Sfez, S., Tagle, D. A., Ziv, Y., Sartiel, A., Collins, F. S., Shiloh, Y., and Rotman, G. (1995) Hum. Mol. Genet. 4, 2025-2032
39. Lavin, M. F., and Shiloh, Y. (1997) Annu. Rev. Immunol. 15, 177-202
40. Cliby, W. A., Roberts, C. J., Cimprich, K. A., Stringer, C. M., Lamb, J. R., Schreiber, S. L., and Friend, S. H. (1998) EMBO J. 17, 159-169
41. Smith, L., Liu, S. J., Goodrich, L., Jacobson, D., Degnin, C., Bentley, N., Carr, A., Flaggs, G., Keegan, K., Hoekstra, M., and Thayer, M. J. (1998) Nat. Genet. 19, 39-46
42. Wright, J. A., Keegan, K. S., Herendeen, D. R., Bentley, N. J., Carr, A. M., Hoekstra, M. F., and Concannon, P. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7445-7450
43. Matsuoka, S., Huang, M., and Elledge, S. J. (1998) Science 282, 1893-1897
44. Liu, Q., Guntuku, S., Cui, X. S., Matsuoka, S., Cortez, D., Tamai, K., Luo, G., Carattini-Rivera, S., DeMayo, F., Bradley, A., Donehower, L. A., and Elledge, S. J. (2000) Genes Dev. 14, 1448-1459
45. Furnari, B., Rhind, N., and Russell, P. (1997) Science 277, 1495-1497
46. Peng, C. Y., Graves, P. R., Thoma, R. S., Wu, Z., Shaw, A. S., and Piwnica-Worms, H. (1997) Science 277, 1501-1505
47. Sanchez, Y., Wong, C., Thoma, R. S., Richman, R., Wu, Z., Piwnica-Worms, H., and Elledge, S. J. (1997) Science 277, 1497-1501
48. Den Haese, G. J., Walworth, N., Carr, A. M., and Gould, K. L. (1995) Mol. Biol. Cell 6, 371-385
49. Banin, S., Moyal, L., Shieh, S., Taya, Y., Anderson, C. W., Chessa, L., Smorodinsky, N. I., Prives, C., Reiss, Y., Shiloh, Y., and Ziv, Y. (1998) Science 281, 1674-1677
50. Canman, C. E., Lim, D. S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B., and Siliciano, J. D. (1998) Science 281, 1677-1679
51. Cortez, D., Wang, Y., Qin, J., and Elledge, S. J. (1999) Science 286, 1162-1166
52. Gatei, M., Scott, S. P., Filippovitch, I., Soronika, N., Lavin, M. F., Weber, B., and Khanna, K. K. (2000) Cancer Res. 60, 3299-3304
53. Gatei, M., Young, D., Cerosaletti, K. M., Desai-Mehta, A., Spring, K., Kozlov, S., Lavin, M. F., Gatti, R. A., Concannon, P., and Khanna, K. (2000) Nat. Genet. 25, 115-119
54. Lim, D. S., Kim, S. T., Xu, B., Maser, R. S., Lin, J., Petrini, J. H., and Kastan, M. B. (2000) Nature 404, 613-617
55. Zhao, S., Weng, Y. C., Yuan, S. S., Lin, Y. T., Hsu, H. C., Lin, S. C., Gerbino, E., Song, M. H., Zdzienicka, M. Z., Gatti, R. A., Shay, J. W., Ziv, Y., Shiloh, Y., and Lee, E. Y. (2000) Nature 405, 473-477
56. Harlow, E., and Lane, D. (1999) Using Antibodies, A Laboratory Manual (Edward, H., ed) Cold Spring Harbor Laboratory Press, New York
57. Chen, G., Yuan, S. S., Liu, W., Xu, Y., Trujillo, K., Song, B., Cong, F., Goff, S. P., Wu, Y., Arlinghaus, R., Baltimore, D., Gasser, P. J., Park, M. S., Sung, P., and Lee, E. Y. (1999) J. Biol. Chem. 274, 12748-12752
58. Ziv, Y., Banin, S., Lim, D. S., Canman, C. E., Kastan, M. B., and Shiloh, Y. (2000) Methods Mol. Biol. 99, 99-108
59. Kraakman-van der Zwet, M., Overkamp, W. J., Friedl, A. A., Klein, B., Verhaegh, G. W., Jaspers, N. G., Midro, A. T., Eckardt-Schupp, F., Lohman, P. H., and Zdzienicka, M. Z. (1999) Mutat. Res. 434, 17-27
60. Chen, P. L., Scully, P., Shew, J. Y., Wang, J. Y., and Lee, W. H. (1989) Cell 58, 1193-1198
61. Longhese, M. P., Paciotti, V., Fraschini, R., Zaccarini, R., Plevani, P., and Lucchini, G. (1997) EMBO J. 16, 5216-5226
62. O'Neill, T., Dwyer, A. J., Ziv, Y., Chan, D. W., Lees-Miller, S. P., Abraham, R. H., Lai, J. H., Hill, D., Shiloh, Y., Cantley, L. C., and Rathbun, G. A. (2000) J. Biol. Chem. 275, 22719-22727
63. Kim, S. T., Lim, D. S., Canman, C. E., and Kastan, M. B. (1999) J. Biol. Chem. 274, 37538-37543
64. Komatsu, K., Miyashita, T., Hang, H., Hopkins, K. M., Zheng, W., Cuddeback, S., Yamada, M., Lieberman, H. B., and Wang, H. G. (2000) Nat. Cell Biol. 2, 1-6
65. Chehab, N. H., Malikzay, A., Stavridi, E. S., and Halazonetis, T. D. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 13777-13782
66. Lakin, N. D., Hann, B. C., and Jackson, S. P. (1999) Oncogene 18, 3989-3995
67. Tibbetts, R. S., Brumbaugh, K. M., Williams, J. M., Sarkaria, J. N., Cliby, W. A., Shieh, S. Y., Taya, Y., Prives, C., and Abraham, R. T. (1999) Genes Dev. 13, 152-157
68. Caspari, T. (2000) Curr. Biol. 10, R315-R317
69. Hirao, A., Kong, Y. Y., Matsuoka, S., Wakeham, A., Ruland, J., Yoshida, H., Liu, D., Elledge, S. J., and Mak, T. W. (2000) Science 287, 1824-1827
70. Shieh, S. Y., Ahn, J., Tamai, K., Taya, Y., and Prives, C. (2000) Genes Dev. 14, 289-300
71. Chehab, N. H., Malikzay, A., Appel, M., and Halazonetis, T. D. (2000) Genes Dev. 14, 278-288
72. Paciotti, V., Lucchini, G., Plevani, P., and Longhese, M. P. (1998) EMBO J. 17, 4199-4209
73. Aboussekhra, A., Vialard, J. E., Morrison, D. E., de la Torre-Ruiz, M. A., Cernakova, L., Fabre, F., and Lowndes, N. F. (1996) EMBO J. 15, 3912-3922
74. Kiser, G. L., and Weinert, T. A. (1996) Mol. Biol. Cell 7, 703-718
75. Bashkirov, V. I., King, J. S., Bashkirova, E. V., Schmuckli-Maurer, J., and Heyer, W. D. (2000) Mol. Cell. Biol. 20, 4393-4404