WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

Nature Structural and Molecular Biology

Volumn 13, Issue 5, 2006, Pages 414-422

  Perry, J Jefferson P ^a,b   Yannone, Steven M ^b   Holden, Lauren G ^a   Hitomi, Chiharu ^a   Asaithamby, Aroumougame ^d   Han, Seungil ^b,c   Cooper, Priscilla K ^b   Chen, David J ^d   Tainer, John A ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c PFIZER INC   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; EXONUCLEASE; METAL ION;

ANIMAL CELL; ARTICLE; CHEMICAL ANALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ANIMALS; BINDING SITES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA; DNA HELICASES; HUMANS; METALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING; RECQ HELICASES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 33745084835     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb1088     Document Type: Article

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