Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury

Aging Cell

Volumn 10, Issue 4, 2011, Pages 572-583

  Kong, Yu X G ^a   van Bergen, Nicole ^a   Trounce, Ian A ^a,b   Bui, Bang V ^a   Chrysostomou, Vicki ^a   Waugh, Hayley ^a   Vingrys, Algis ^a   Crowston, Jonathan G ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b Royal Victorian Eye and Ear Hospital   (Australia)

Author keywords

Aging; Electroretinogram; Glaucoma; Mitochondria; Polymerase gamma retina

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRESS; CONTROLLED STUDY; ELECTRORETINOGRAM; GENE MUTATION; IN VIVO STUDY; INTRAOCULAR PRESSURE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; POINT MUTATION; PRIORITY JOURNAL; RETINA GANGLION CELL; RETINA INJURY; RETINA NERVE CELL;

ANIMALS; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; INTRAOCULAR PRESSURE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEURONS; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; RETINA; STRESS, PHYSIOLOGICAL;

MUS MUSCULUS;

EID: 79960323487     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2011.00690.x     Document Type: Article

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